KEGG   Mus musculus (house mouse): 17342
Entry
17342             CDS       T01002                                 
Symbol
Mitf, BCC2, Bhlhe32, Gsfbcc2, Vitiligo, Wh, bw, mi, vit
Name
(RefSeq) microphthalmia-associated transcription factor isoform 1
  KO
K09455  microphthalmia-associated transcription factor
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04137  Mitophagy - animal
mmu04142  Lysosome biogenesis
mmu04380  Osteoclast differentiation
mmu04916  Melanogenesis
mmu05200  Pathways in cancer
mmu05202  Transcriptional misregulation in cancer
mmu05218  Melanoma
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome biogenesis
    17342 (Mitf)
   04137 Mitophagy - animal
    17342 (Mitf)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    17342 (Mitf)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    17342 (Mitf)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    17342 (Mitf)
   05202 Transcriptional misregulation in cancer
    17342 (Mitf)
  09162 Cancer: specific types
   05218 Melanoma
    17342 (Mitf)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    17342 (Mitf)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Ubiquitous bHLH-ZIP factors
    17342 (Mitf)
SSDB
Motif
Pfam: MITF_TFEB_C_3_N DUF3371 HLH bHLH_IRO3 DUF726
Other DBs
NCBI-GeneID: 17342
NCBI-ProteinID: NP_001106669
MGI: 104554
Ensembl: ENSMUSG00000035158
UniProt: Q08874
Structure
Position
6:97783966..97998321
AA seq 526 aa
MQSESGIVADFEVGEEFHEEPKTYYELKSQPLKSSSSAEHSGASKPPLSSSTMTSRILLR
QQLMREQMQEQERREQQQKLQAAQFMQQRVAVSQTPAINVSVPTTLPSATQVPMEVLKVQ
THLENPTKYHIQQAQRHQVKQYLSTTLANKHASQVLSSPCPNQPGDHAMPPVPGSSAPNS
PMAMLTLNSNCEKEAFYKFEEQSRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE
ILGLMDPALQMANTLPVSGNLIDLYSNQGLPPPGLTISNSCPANLPNIKRELTACIFPTE
SEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDY
IRKLQREQQRAKDLENRQKKLEHANRHLLLRVQELEMQARAHGLSLIPSTGLCSPDLVNR
IIKQEPVLENCSQELVQHQADLTCTTTLDLTDGTITFTNNLGTMPESSPAYSIPRKMGSN
LEDILMDDALSPVGVTDPLLSSVSPGASKTSSRRSSMSAEETEHAC
NT seq 1581 nt   +upstreamnt  +downstreamnt
atgcagtccgaatcgggaatcgtggcggatttcgaagtcggggaggagtttcacgaagaa
cccaaaacctattacgaactcaaaagtcaacctctgaagagcagcagttctgcagagcat
tctggggcctccaagcctccgttaagctcctccactatgacatcacgcatcttgctacgc
cagcaactcatgcgtgagcagatgcaggagcaggagcgcagggagcagcagcagaagctg
caggcagcccagttcatgcaacagagagtggccgtgagtcagacaccagccataaacgtc
agcgtgcccaccacccttccctctgccacccaggtgccgatggaagtccttaaggtgcag
acccacctggaaaaccccaccaagtaccacatacagcaagctcagaggcaccaggtaaag
cagtacctttctaccactttagcaaataaacatgccagccaagtcctgagctcaccatgt
ccaaaccagcctggcgaccatgccatgccaccagtgccggggagcagcgcacccaacagc
cctatggctatgctcactcttaactccaactgtgaaaaagaggcattttataagtttgag
gagcagagcagggcagagagtgagtgcccaggtatgaacacgcactctcgagcgtcgtgc
atgcagatggatgatgtaattgatgacatcatcagcctggaatcaagttataatgaagaa
attttgggcttgatggatccggccttgcaaatggcaaatacgttacccgtctctggaaac
ttgatcgacctctacagcaaccagggcctgccaccgccaggccttaccatcagcaactcc
tgtccagccaaccttcccaacataaaaagggagctcacagcgtgtattttccccacagag
tctgaagcaagagcattggctaaagagaggcagaaaaaggacaatcacaacttgattgaa
cgaagaagaagatttaacataaacgaccgcattaaggagctaggtactctgatccccaag
tcaaatgatccagacatgcggtggaacaagggaaccattctcaaggcctctgtggactac
atccggaagttgcaacgggaacagcaacgagctaaggaccttgaaaaccgacagaagaag
ctggagcatgcgaaccggcacctgctgctcagagtacaggagctggagatgcaggctaga
gcgcatggactttcccttatcccatccaccggtctctgctcgcctgatctggtgaatcgg
atcatcaagcaagaaccagttcttgagaactgcagccaggaacttgtacagcaccaggca
gacctgacatgtacgacaactctggatctcacggacggtaccatcacctttaccaacaac
ctcggcaccatgccggagagcagcccggcctacagcatccccaggaagatgggctccaac
ttggaagacatcctgatggacgatgccctctcacctgttggagtcaccgacccactgctg
tcatcagtgtcgccaggagcttcaaaaacaagcagccggaggagcagtatgagcgcagaa
gaaacggagcatgcgtgttag

  All links  
Gene (10)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (26)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (64)   
   RefSeq(nuc) (24)   
   GenBank (20)   
   EMBL (20)   
3D Structure (5)   
   PDB (5)   
Protein domain (5)   
   Pfam (5)   
All databases (110)   

Download RDF
DBGET integrated database retrieval system