KEGG   Mus musculus (house mouse): 17888
Entry
17888             CDS       T01002                                 
Symbol
Myh6, A830009F23Rik, Myhc-a, Myhca, alpha-MHC, alphaMHC
Name
(RefSeq) myosin-6
  KO
K17751  myosin heavy chain 6/7
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04022  cGMP-PKG signaling pathway
mmu04260  Cardiac muscle contraction
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04814  Motor proteins
mmu04820  Cytoskeleton in muscle cells
mmu04919  Thyroid hormone signaling pathway
mmu05410  Hypertrophic cardiomyopathy
mmu05414  Dilated cardiomyopathy
mmu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    17888 (Myh6)
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    17888 (Myh6)
   04820 Cytoskeleton in muscle cells
    17888 (Myh6)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    17888 (Myh6)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    17888 (Myh6)
   04261 Adrenergic signaling in cardiomyocytes
    17888 (Myh6)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    17888 (Myh6)
   05414 Dilated cardiomyopathy
    17888 (Myh6)
   05416 Viral myocarditis
    17888 (Myh6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:mmu04812]
    17888 (Myh6)
Cytoskeleton proteins [BR:mmu04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     17888 (Myh6)
SSDB
Motif
Pfam: Myosin_head Myosin_tail_1 Myosin_N FKBP15 Rod_CreS CCDC39 CEP135_TSGA10_CC Filament IQ NPHP3_N DUF3851 AAA_22
Other DBs
NCBI-GeneID: 17888
NCBI-ProteinID: NP_001157643
MGI: 97255
Ensembl: ENSMUSG00000040752
UniProt: Q02566 B2RQQ1
Structure
Position
14:complement(55179378..55205553)
AA seq 1938 aa
MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEYVKAKVVSREGGKVT
AETENGKTVTIKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGL
FCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES
GAGKTVNTKRVIQYFASIAAIGDRSKKENPNANKGTLEDQIIQANPALEAFGNAKTVRND
NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD
MLLVTNNPYDYAFVSQGEVSVASIDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHY
GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ
VYYSIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECM
FPKASDMTFKAKLYDNHLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNIMGWLEKNKD
PLNETVVGLYQKSSLKLMATLFSTYASADTGDSGKGKGGKKKGSSFQTVSALHRENLNKL
MTNLKTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF
RQRYRILNPAAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD
ERLSRIITRIQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP
LLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL
NDAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE
LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN
TLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE
KLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD
LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD
SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE
YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ
LEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETD
AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA
AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF
KRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKI
LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKM
EGDLNEMEIQLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVERRN
NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ
TEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD
EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK
KNLMRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN
KLRAKSRDIGAKKMHDEE
NT seq 5817 nt   +upstreamnt  +downstreamnt
atgacggacgcccagatggctgacttcggggcagcagcccagtacctccgaaagtcagag
aaggaacgcctagaggcccagacccggccctttgacatccgcacggagtgcttcgtgcct
gatgacaaggaggagtatgttaaggccaaggtcgtgtcccgggaagggggcaaagtcact
gcggaaactgaaaacggaaagacggtgaccataaaggaggaccaggtgatgcagcagaac
ccacccaagttcgacaagatcgaggacatggccatgctgaccttcctgcacgagccggct
gtgctgtacaacctcaaggagcgctacgcggcctggatgatctatacctactcaggcctc
ttctgcgtcaccgtcaacccctataagtggctgcctgtgtacaatgcggaagtggtggcc
gcctaccggggcaagaagaggagcgaggcccctcctcacatcttctccatctctgacaac
gcctatcagtacatgctgacagatcgggagaatcagtccatcctcatcaccggagaatcc
ggagcggggaagactgtgaacacaaaacgtgtcatccagtactttgccagcattgcagcc
ataggggaccgtagcaagaaggaaaatcctaatgcaaacaagggcaccctggaggaccag
attatccaggctaaccccgctctggaggccttcggcaacgccaagactgtccggaatgac
aactcctcccgctttgggaaattcatcaggatccactttggagctactggaaagctggct
tctgcagacatagagacctaccttctggagaagtcccgggtgatcttccagctaaaggct
gagaggaactaccacatcttctaccagatcctgtccaacaagaagccggagctgctggac
atgctgctggtcaccaacaacccatacgactacgccttcgtctctcagggagaggtgtcc
gtggcctccattgatgactctgaggagctcttggccactgatagtgcctttgatgtgctg
agcttcacggcagaggagaaggctggtgtctacaagctgacaggggccatcatgcactac
ggaaacatgaagttcaagcagaagcagcgggaggagcaggcggagcctgatggcacagaa
gatgctgacaaatctgcctaccttatggggctgaactcagctgacctgctcaagggcctg
tgtcaccctcgggtgaaggtggggaacgagtatgtcaccaaggggcagagtgtacagcaa
gtgtactattccatcggggcactggccaagtcagtgtacgagaagatgttcaactggatg
gtgacacgcatcaacgcaaccctggagaccaagcagccgcgccagtacttcataggtgtc
ctggacattgccggctttgagatcttcgatttcaacagctttgagcagctgtgcatcaac
ttcaccaatgagaagctgcagcagttcttcaaccaccacatgttcgtgctggagcaggag
gagtacaagaaggagggcattgagtgggagtttatcgacttcggcatggacctgcaggcc
tgcatcgacctcatcgagaagcccatgggcatcatgtccatcctcgaggaggagtgcatg
ttccccaaggcctcagacatgaccttcaaggccaagctgtatgacaaccacctgggcaaa
tccaacaacttccagaagcctcgcaatgtcaaggggaagcaggaagcccacttctccttg
gtccactatgctggcaccgtggactacaacattatgggctggctggaaaagaacaaggac
ccactcaatgagacggtggtgggtttgtaccagaagtcctccctcaagctcatggctaca
ctcttctctacctatgcttctgctgataccggtgacagtggtaaaggcaaaggaggcaag
aagaaaggctcatccttccaaacagtgtctgctctccaccgggaaaatctgaacaagctg
atgacaaacctgaagaccacccaccctcactttgtgcgctgcatcattcccaacgagcga
aaggctccaggggtgatggacaaccccctggtcatgcaccagctgcgatgcaatggcgtg
ctggagggtatccgcatctgcaggaagggcttccccaaccgcattctctatggggacttc
cggcagaggtatcgcatcctgaacccagcagccatccctgaggggcaattcattgatagc
aggaaaggggctgagaaactgctgggctccctggacattgaccacaaccaatacaagttt
ggccacaccaaggtgttcttcaaggcgggcctgctggggctgctcgaggagatgcgagat
gagaggctgagccgtatcatcaccagaatccaggcccaggcccgagggcagctcatgcgc
attgagttcaagaagatagtggaacgcagggatgccctgctggttatccagtggaacatt
cgggccttcatgggggtcaagaattggccatggatgaagctctacttcaagatcaaaccg
ctgctgaagagcgcagagacggagaaggagatggccaacatgaaggaggagtttgggcga
gtcaaagatgcactggagaagtctgaggctcgccgcaaggagctggaggagaagatggtg
tccctgctgcaggagaagaatgacctacagctccaagtgcaggcggaacaagacaacctc
aatgatgcagaggagcgctgtgaccagctgatcaagaacaagatccagctggaggccaag
gtgaaggagatgaccgagaggctggaggacgaggaggagatgaacgccgagctcactgcc
aagaagcgcaagctggaagatgagtgctcagagctcaagaaggatattgatgacctggag
ctgacgctggccaaggtggaaaaggaaaagcatgcaacagagaacaaggttaaaaaccta
acagaggagatggctgggctggatgaaatcattgccaagctgaccaaagagaagaaagct
ctgcaagaagcccaccagcaagccctcgatgacctgcaggctgaagaagacaaggtcaac
acgctgaccaagtccaaagtcaagctggagcagcaggtggatgatctggagggatccctg
gagcaggagaagaaagtgcgcatggacctagagcgagccaagcggaagctggagggagac
ctgaagctgacccaggagagcatcatggacctggagaatgacaagcttcagctggaagaa
aagctcaagaagaaagagttcgacatcagtcagcagaacagtaaaattgaggacgagcag
gccctggctcttcagctgcagaagaaactgaaggaaaaccaggcacgcatcgaggagctg
gaggaggagctggaggcagagcgcacagcccgggctaaggtggagaagctgcgctctgac
ctgtcccgggagctggaggagatcagtgagaggctggaggaggcaggcggggccacatcc
gtgcagatagagatgaataagaagcgcgaggccgagttccagaagatgcggcgggacctg
gaggaggccacgctgcagcacgaggccacggcggcggccctgcgcaagaagcatgctgac
agcgtggcggagctgggcgagcagatcgacaacctccagcgggtgaagcagaagctggag
aaagagaagagcgagttcaagctggagctggatgacgtcacctccaacatggagcagatc
atcaaggccaaggccaacctggagaaagtgtcccggacactggaggaccaggccaatgag
taccgcgtgaagctggaagaagcccagcgctccctcaatgacttcaccacacagcgagcc
aagctgcagacagagaacggggagttggctaggcaactggaagaaaaggaggcattgatt
tcccagctgacccgaggcaagctctcctacacccagcagatggaggacctcaagaggcaa
ctggaggaggaaggcaaggccaagaacgccctggcccacgcactgcaatcatcccggcat
gactgtgacctgctgagggaacagtatgaagaagaaatggaggccaaggctgagctacag
cgtgtcctgtccaaggccaactcagaggtggcccagtggaggaccaagtatgagacggat
gccatacagaggacggaggagctggaggaagccaagaagaagctggctcagaggctgcag
gatgcagaggaggcagtggaggccgtcaacgccaagtgttcctccctggagaagaccaag
cacaggctgcagaatgagatcgaggacctgatggtggacgtggagcgctccaatgccgcc
gccgcagccctggacaagaagcagaggaactttgacaagatcctggctgagtggaagcag
aagtatgaggagtcgcagtcagagctggagtcttcccagaaggaggcgcgctccctgagc
acagagctcttcaagctcaagaacgcctatgaggagtctctggagcacctggagaccttc
aagcgggagaacaagaacctccaggaggagatctcagacctgactgaacagctgggagaa
ggggggaaaaacgtgcacgagctggagaagatccgcaaacagctggaggtggagaagctg
gagctgcagtcagccctggaggaggctgaggcctccctggagcacgaggagggcaagatc
ctccgtgcccagctggagttcaaccagatcaaggcagagatcgaaaggaagctggcagag
aaggatgaggagatggagcaggccaagcgcaaccacctgcggatggtggactccctgcag
acctccctggatgcggagacacgcagccgcaatgaggccctgcgggtgaagaagaagatg
gagggcgacctcaacgagatggagatccagctcagccaggccaatagaatagcctcagag
gcacagaaacacctgaagaattctcaagctcacttgaaggacacccagctccagctggat
gatgctgtccatgccaatgacgacctgaaggagaacatcgccatcgtggaacggcgcaac
aacctgctgcaggcggagctggaggagctgcgggctgtggtggagcagacggagcggtct
cggaagctggcagagcaggagctgattgagaccagcgagcgggtgcagctgctgcactcg
cagaacaccagcctcatcaaccagaagaagaagatggagtcagacctgacccaactccag
acagaagtagaggaggcagtgcaggagtgtaggaacgcagaggagaaggccaagaaggcc
atcacagatgccgcaatgatggctgaggagctgaagaaggagcaggacaccagcgcccac
ctggagcgcatgaagaagaacatggagcagaccatcaaggacttgcagcaccgtctggac
gaggcagagcagatcgccctcaagggcggcaagaagcagctgcagaagctggaggcccgg
gtccgggagctggagaatgagctggaggctgagcagaagcgcaatgcagagtcggtgaag
ggcatgaggaagagcgagcggcgcatcaaggagctcacctaccagacagaggaagacaag
aagaacttaatgcggctgcaggacctggtggacaagctacagttgaaggtgaaggcctac
aagcgccaggctgaggaggcggaggagcaggccaacaccaacctgtccaagttccgcaag
gtgcagcacgagctggatgaggcggaggagagggcggacatcgccgagtcccaggtcaac
aagctgcgggccaagagccgggacattggtgccaagaagatgcacgacgaggaataa

  All links  
Gene (26)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (41)   
   RefSeq(nuc) (5)   
   GenBank (18)   
   EMBL (18)   
3D Structure (4)   
   PDB (4)   
Protein domain (12)   
   Pfam (12)   
All databases (91)   

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