KEGG   Mus musculus (mouse): 18019
Entry
18019             CDS       T01002                                 

Gene name
Nfatc2, AI607462, NF, NF-ATc2, NF-ATp, NFA, NFAT1, NFAT1-D, Nfatp
Definition
(RefSeq) nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
  KO
K17332  nuclear factor of activated T-cells, cytoplasmic 2
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04022  cGMP-PKG signaling pathway
mmu04218  Cellular senescence
mmu04310  Wnt signaling pathway
mmu04360  Axon guidance
mmu04370  VEGF signaling pathway
mmu04380  Osteoclast differentiation
mmu04625  C-type lectin receptor signaling pathway
mmu04650  Natural killer cell mediated cytotoxicity
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04660  T cell receptor signaling pathway
mmu04662  B cell receptor signaling pathway
mmu04921  Oxytocin signaling pathway
mmu05135  Yersinia infection
mmu05161  Hepatitis B
mmu05163  Human cytomegalovirus infection
mmu05166  Human T-cell leukemia virus 1 infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    18019 (Nfatc2)
   04370 VEGF signaling pathway
    18019 (Nfatc2)
   04022 cGMP-PKG signaling pathway
    18019 (Nfatc2)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    18019 (Nfatc2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    18019 (Nfatc2)
   04650 Natural killer cell mediated cytotoxicity
    18019 (Nfatc2)
   04660 T cell receptor signaling pathway
    18019 (Nfatc2)
   04658 Th1 and Th2 cell differentiation
    18019 (Nfatc2)
   04659 Th17 cell differentiation
    18019 (Nfatc2)
   04662 B cell receptor signaling pathway
    18019 (Nfatc2)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    18019 (Nfatc2)
  09158 Development and regeneration
   04360 Axon guidance
    18019 (Nfatc2)
   04380 Osteoclast differentiation
    18019 (Nfatc2)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    18019 (Nfatc2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    18019 (Nfatc2)
   05170 Human immunodeficiency virus 1 infection
    18019 (Nfatc2)
   05161 Hepatitis B
    18019 (Nfatc2)
   05163 Human cytomegalovirus infection
    18019 (Nfatc2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    18019 (Nfatc2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    18019 (Nfatc2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    18019 (Nfatc2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    18019 (Nfatc2)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) NF-AT
    18019 (Nfatc2)
SSDB
Motif
Pfam: RHD_dimer RHD_DNA_bind TIG
Other DBs
NCBI-GeneID: 18019
NCBI-ProteinID: NP_035029
MGI: 102463
Ensembl: ENSMUSG00000027544
Vega: OTTMUSG00000016052
UniProt: Q60591 B5B2P6
Position
2 H3; 2 88.91 cM
AA seq 927 aa
MDVPEPQPDPDGGDGPGHEPGGSPQDELDFSILFDYDYLNPIEEEPIAHKAISSPSGLAY
PDDVLDYGLKPCNPLASLSGEPPGRFGEPDSIGFQNFLSPVKPAGASGPSPRIEITPSHE
LMQAGGALRGRDAGLSPEQPALALAGVAASPRFTLPVPGYEGYREPLCLSPASSGSSASF
ISDTFSPYTSPCVSPNNAGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPV
PRPASRSSSPGAKRRHSCAEALVAPLPAASPQRSRSPSPQPSPHVALQDDSIPAGYPPTA
GSAVLMDALNTLATDSPCGIPSKIWKTSPDPTPVSTAPSKAGLARHIYPTVEFLGPCEQE
ERRNSAPESILLVPPTWPKQLVPAIPICSIPVTASLPPLEWPLSNQSGSYELRIEVQPKP
HHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHR
ITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRK
NTRVRLVFRVHVPEPSGRIVSLQAASNPIECSQRSAHELPMVERQDMDSCLVYGGQQMIL
TGQNFTAESKVVFMEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRVPVKVNF
YVINGKRKRSQPQHFTYHPVPAIKTEPSDEYEPSLICSPAHGGLGSQPYYPQHPMLAESP
SCLVATMAPCQQFRSGLSSPDARYQQQSPAAALYQRSKSLSPGLLGYQQPSLLAAPLGLA
DAHRSVLVHAGSQGQGQGSTLPHTSSASQQASPVIHYSPTNQQLRGGGHQEFQHIMYCEN
FGPSSARPGPPPINQGQRLSPGAYPTVIQQQTAPSQRAAKNGPSDQKEALPTGVTVKQEQ
NLDQTYLDDVNEIIRKEFSGPPSRNQT
NT seq 2784 nt   +upstreamnt  +downstreamnt
atggacgtcccggagccgcagcccgaccccgatggcggggacggccccggccacgagccc
gggggcagtccccaagacgagctggacttttccatcctcttcgattatgactatctgaac
cctatcgaagaagaaccgatcgcacataaggccatcagctcaccctccggactcgcatac
ccggatgatgtcctggactatggcctcaagccatgcaacccccttgccagtctctctggc
gagccccctggccggttcggagagccggatagtatagggttccagaactttctgagcccg
gtcaagccagcaggggcttcgggcccgagccctcggatcgagatcactccatcccacgaa
ctgatgcaggcagggggggccctccgtgggagagacgccggcctgtcccccgagcagccg
gccctggccctggccggcgtggccgccagcccgaggttcacactgcccgtgcccggctac
gagggctaccgcgagccgctttgcttgagccccgctagcagcggctcctctgccagcttc
atttctgacaccttctccccctacacctcgccctgcgtctcacccaataacgccgggccc
gacgacctgtgtccccagtttcaaaacatccctgctcattattcccccagaacctctcca
ataatgtcacctcgaaccagcctcgccgaggacagctgcctgggccgacactcgcccgtg
ccccgtccggcatcccgctcctcctcacccggtgccaagcggaggcattcgtgcgcagag
gctttggttgctcctctgcccgcagcctcaccccagcgctcccggagcccctcgccacag
ccctcgcctcacgtggcactgcaggacgacagcatccccgctgggtacccccccacggcc
ggctctgctgttctcatggatgccctcaacaccctggccaccgactcgccctgcgggatc
ccctccaagatatggaagaccagtcctgacccgacgcctgtgtccaccgctccgtccaag
gctggcctggcccgccacatctaccctactgtggagttcctggggccatgtgagcaggag
gagaggaggaattccgctccagagtccatcctgctggtaccacctacttggcccaagcag
ttggtgccggccattcccatctgcagcatccctgtgactgcatccctcccaccactcgag
tggccactctccaatcagtcgggctcctatgagctacggattgaggtccaacccaagccc
catcaccgggcccactatgagacggagggcagccgtggcgctgtcaaagccccaacagga
ggacaccctgtggtgcagctccacggctacatggagaacaagcctctggggcttcagatc
ttcattgggacagcagatgagaggatccttaagccgcacgccttctaccaagtacacagg
atcactgggaaaacggtcaccaccacgagctatgagaagatcgtaggcaacaccaaggtc
ctggagatccccctggagccaaagaacaacatgagagccaccatcgactgtgcaggcatc
ctgaagctccgaaacgctgacatcgagctgcggaagggcgagacggacatcggcaggaag
aacacgcgtgtgcgcctggtgttccgcgtgcacgtcccagagcccagtgggcgcatcgtc
tccctgcaggctgcgtccaaccccatcgagtgctctcagcgctctgcccacgagctgccc
atggtggagagacaagacatggacagctgcctggtctacgggggccagcagatgatcctc
acgggccagaacttcacagcggagtccaaggttgtgttcatggagaagactacagatggg
cagcagatttgggagatggaagctacggtggataaagacaagagccagcctaacatgctt
tttgttgagatccccgagtatcggaacaagcacatccgcgtgcccgtgaaagtcaacttc
tacgtcatcaacggaaagaggaaacgaagtcagccacagcactttacctaccacccagtc
cctgccatcaagacagagcccagcgatgagtatgaaccatctttgatctgcagccccgcc
catggaggcctggggagccagccatattacccacagcacccaatgctggccgagtccccc
tcctgccttgtggctaccatggccccctgccaacagttccgctcggggctctcatccccc
gatgctcgctaccaacagcagagccccgcagctgccctctaccagagaagcaagagcctg
agtcccggcctgctgggctaccagcagccgtccctcctggcagcacccttgggtctggct
gatgcccaccgctctgtgctggtgcatgctggttctcaggggcaggggcagggctccacc
ctgccacacacatcctcggccagccagcaggcctcacccgtgatccactactcacccacc
aaccagcagcttcgcggtgggggtcaccaggagttccagcatatcatgtactgtgaaaac
ttcggccccagctctgccaggcctggcccgcctcccatcaaccaaggtcagaggctgagc
ccgggcgcctaccccacagtcatccaacaacagactgccccgagccaaagagctgccaaa
aacggacccagtgaccagaaggaagctctgcccacgggagtgaccgtcaaacaggaacag
aacctggaccagacctacctggatgacgttaatgaaatcatcaggaaggagttttcagga
cctccctcccgaaatcagacctag

DBGET integrated database retrieval system