KEGG   Mus musculus (house mouse): 18222
Entry
18222             CDS       T01002                                 
Symbol
Numb, Nb
Name
(RefSeq) protein numb homolog isoform 1
  KO
K06057  numb
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04330  Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    18222 (Numb)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    18222 (Numb)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   LDLR adaptor proteins
    18222 (Numb)
SSDB
Motif
Pfam: PID NumbF PTB PID_2
Other DBs
NCBI-GeneID: 18222
NCBI-ProteinID: NP_001129547
MGI: 107423
Ensembl: ENSMUSG00000021224
UniProt: Q9QZS3
Structure
Position
12:complement(83840808..83968708)
AA seq 653 aa
MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD
RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA
TFDASRTTFTREGSFRVTTATEQAEREEIMKQLQDAKKAETDKTVVGPSVAPGNTAPSPS
SPTSPTPDGTASSEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE
LPSTMQRKTDFPIKNTVPEVEGEAESISSLCSQITSAFSTPSEDPFSSAPMTKPVTLVAP
QSPVLQANGTDSASHVLTAKPANTALAHVAMPVRETNPWAHVPDAANKEIAAIHPGTEWG
QSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQVSAAPLQPVLQPPPPAAIAPP
APPFQGHAFLTSQPVPVGVVPPLQPAFVPTQSYPVANGMPYPASNVPVVGITPSQMVANV
FGTAGHPQTTHPHQSPSLAKQQTFPQYETSSATTSPFFKPPAQHLNGSAAFNGVDNGGLA
SGNRHAEVPPGTCPVDPFEAQWAALESKSKQRTNPSPTNPFSSDLQKTFEIEL
NT seq 1962 nt   +upstreamnt  +downstreamnt
atgaacaaactacggcaaagcttcaggagaaagaaagacgtttatgtcccagaggccagc
cgtccacatcagtggcagacagatgaagaaggagtccgcactggaaagtgtagcttccca
gttaagtacctcggccacgtagaagttgatgagtcaagaggaatgcacatctgtgaagat
gccgtaaagagattgaaagctgaaaggaagttcttcaaaggcttctttggaaaaacggga
aagaaagcagtgaaggccgttctgtgggtgtcagcggatgggctcagagttgtggacgag
aaaactaaggacctcatagttgaccagacaatagaaaaagtttccttctgtgccccagat
aggaactttgacagagccttttcttacatatgtcgtgatggcaccactcggcgatggatc
tgtcattgtttcatggctgtcaaagacacgggggaaagactgagccacgccgtgggctgt
gcttttgcagcctgtttagagcgtaaacagaagcgggagaaggagtgtggcgtcactgct
acttttgatgccagtagaaccactttcacaagagaaggatcattccgtgtcacaactgcc
actgagcaagccgaaagagaggagatcatgaaacagttgcaagatgccaagaaagctgag
acagacaagacagttgttggtccatcagtggctcctggcaacactgctccatccccatcc
tctcccacctctcccactccggatggcactgcatcttcagagatgaacaatccccatgct
atcccacgccggcatgcaccaattgaacagcttgctcgtcaaggctctttccggggattt
cctgctcttagccagaagatgtcaccctttaaacgccagctgtccctacgcatcaatgag
ttgccttccactatgcagaggaagaccgatttcccaataaaaaacacagtgcccgaggtg
gaaggagaggccgagagcatcagctccttgtgttcccagatcaccagtgccttcagcacg
ccctctgaggaccccttctcctccgccccaatgaccaaaccagtgacattggtggcacca
cagtctcctgtgttacaagctaatggcactgactcagcctcccatgtgcttactgctaag
ccagccaatactgctctagcacacgtagcaatgcctgtccgtgaaaccaacccctgggcc
catgtccctgatgctgctaacaaggaaattgcagccatacatccggggactgagtggggt
cagtcttctggtgctgcctctccaggtctcttccaggctggtcacagacgcactccctct
gaagctgaccgctggttagaagaagtgtcaaagagtgtgcgggcccagcagcctcaggtc
tcagctgcccctctgcagccagttctccagccgcctccgcccgccgccattgcccctcca
gcacctcctttccaaggacatgccttcctcacgtcccagcctgtgcccgtgggtgtggtc
ccacccctacaaccagcctttgtccctacccagtcctaccctgtggccaacgggatgccc
tacccagcctctaatgtgcctgtagtgggcatcaccccatcccagatggtagccaatgtg
tttggcactgcaggccaccctcagacaactcatccacatcagtcgccaagcctggccaag
cagcagacattccctcaatatgagacaagtagtgctaccaccagtcccttctttaagcct
cctgctcagcacctcaatggttctgcagctttcaatggtgtagacaatggtgggctagcc
tcaggaaacaggcatgcagaagtccctccaggcacctgcccagtggatcctttcgaagct
cagtgggccgcactagaaagcaagtccaagcagcgtacaaatccttctcctaccaaccct
ttctccagtgacttacagaaaacatttgaaatagaactttag

  All links  
Gene (14)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (36)   
   RefSeq(nuc) (14)   
   GenBank (11)   
   EMBL (11)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   Pfam (4)   
All databases (70)   

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