KEGG   Mus musculus (mouse): 18597
Entry
18597             CDS       T01002                                 

Gene name
Pdha1, Pdha, Pdha-1
Definition
(RefSeq) pyruvate dehydrogenase E1 alpha 1
  KO
K00161  pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00020  Citrate cycle (TCA cycle)
mmu00620  Pyruvate metabolism
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu04066  HIF-1 signaling pathway
mmu04922  Glucagon signaling pathway
mmu05230  Central carbon metabolism in cancer
mmu05415  Diabetic cardiomyopathy
Module
mmu_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    18597 (Pdha1)
   00020 Citrate cycle (TCA cycle)
    18597 (Pdha1)
   00620 Pyruvate metabolism
    18597 (Pdha1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    18597 (Pdha1)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    18597 (Pdha1)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    18597 (Pdha1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    18597 (Pdha1)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     18597 (Pdha1)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-GeneID: 18597
NCBI-ProteinID: NP_032836
MGI: 97532
Ensembl: ENSMUSG00000031299
Vega: OTTMUSG00000019453
UniProt: P35486 Q3UFJ3
Position
X F4; X 73.95 cM
AA seq 390 aa
MRKMLAAVSRVLAGSAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgaggaagatgcttgccgctgtatcccgcgtgttggcaggctctgcgcagaagccggca
agccgagtgctggttgcttcccgtaattttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccccccagtcaccacagtgctcaccagagaggat
gggctcaagtactacaggatgatgcagactgtgcgccggatggagctaaaggcggatcag
ctgtataagcagaaaatcattcgtggtttctgtcacttgtgtgatggtcaggaagcctgc
tgcgtgggcctggaggctggcataaaccctacggaccacctcatcactgcctatcgagca
catggcttcaccttcactcggggcctgcctgtgcgagcaattcttgcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggcgggtcaatgcacatgtacgccaagaacttc
tatggaggcaacggcatcgttggagctcaggtgcccctgggagcaggaattgccctggcc
tgcaagtacaatggaaaagatgaggtctgtttgacattatacggcgatggtgctgctaat
cagggtcagatctttgaagcttacaatatggcagcactgtggaaattaccttgcattttt
atctgtgagaacaaccgctatggcatggggacgtctgttgagagagcagcagccagcacg
gactactacaaaagaggagattttattcctggactcagggtagatggaatggatatcttg
tgcgtccgagaggcaacaaagtttgcggctgcctattgcaggtctggtaaggggcccatc
ctgatggagctccagacttaccgctaccatggacacagcatgagtgaccctggagtaagc
taccgcactcgagaagaaatccaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatcttgcaagtgttgaagaattaaaggagattgatgtg
gaagtgaggaaagaaatcgaggatgctgcccagtttgccacggctgatcctgagcccccg
ttggaggaactaggctatcacatctacagcagtgatcctccctttgaagtgcgtggtgcc
aaccagtggatcaagtttaagtcagtcagttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (31)   
   RefSeq(nuc) (1)   
   GenBank (15)   
   EMBL (15)   
Protein domain (3)   
   Pfam (3)   
All databases (85)   

Download RDF
KEGG   Mus musculus (mouse): 18598
Entry
18598             CDS       T01002                                 

Gene name
Pdha2, Pd, Pdhal
Definition
(RefSeq) pyruvate dehydrogenase E1 alpha 2
  KO
K00161  pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00020  Citrate cycle (TCA cycle)
mmu00620  Pyruvate metabolism
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu04066  HIF-1 signaling pathway
mmu04922  Glucagon signaling pathway
mmu05230  Central carbon metabolism in cancer
mmu05415  Diabetic cardiomyopathy
Module
mmu_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    18598 (Pdha2)
   00020 Citrate cycle (TCA cycle)
    18598 (Pdha2)
   00620 Pyruvate metabolism
    18598 (Pdha2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    18598 (Pdha2)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    18598 (Pdha2)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    18598 (Pdha2)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    18598 (Pdha2)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     18598 (Pdha2)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-GeneID: 18598
NCBI-ProteinID: NP_032837
MGI: 97533
Ensembl: ENSMUSG00000047674
Vega: OTTMUSG00000053679
UniProt: P35487
Position
3; 3 H1
AA seq 391 aa
MRKMLTAVLSHVFSGMVQKPALRGLLSSLKFSNDATCDIKKCDLYRLEEGPPTSTVLTRA
EALKYYRTMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGFCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYGKNFYGGNGIVGAQVPLGAGVAF
ACKYLKNGQVCLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNLYGMGTSNERSAAS
TDYHKKGFIIPGLRVNGMDILCVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGI
SYRSREEVHNVRSKSDPIMLLRERIISNNLSNIEELKEIDADVKKEVEDAAQFATTDPEP
AVEDIANYLYHQDPPFEVRGAHKWLKYKSHS
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgaggaaaatgctgaccgctgtgctgtctcacgtattttcgggaatggtccaaaagcca
gctctcagaggactgctgtcatctctgaagttctccaacgacgccacctgtgacattaag
aaatgtgacctgtaccggctggaggagggcccaccgacctccaccgtgctcacccgagcc
gaggccctcaagtactaccggaccatgcaggtaattcggcgcatggagttgaaggccgac
cagctgtataagcagaaattcatccgtggtttctgtcacctgtgtgatgggcaggaagcc
tgctgcgtggggctggaggcagggataaatcccacggatcacgtcatcacgtcctaccgg
gctcatggcttctgctacacgcgaggactgtccgtgaagtccattctcgccgagctgact
ggacgcaaaggaggctgtgctaaaggcaagggaggctccatgcacatgtacggcaagaac
ttctacggtggcaatggcattgttggggcccaggtacccctgggagctggtgtggctttt
gcctgtaaatacctgaagaatggtcaggtctgcttggctttgtacggcgatggtgcggct
aaccaagggcaggtattcgaagcatacaatatgtcagccttgtggaaattaccctgtgtt
ttcatctgtgagaataacctctatggaatgggaacctccaacgagagatcagcagccagt
actgattaccacaagaaaggttttattatccccggactgagggtgaatgggatggatatt
ctctgtgttcgggaggcaaccaagtttgcagctgatcactgcagatctggaaaggggccc
attgtgatggagctgcagacctaccgttatcatggacacagtatgagcgacccagggatc
agttatcgttcacgagaagaagttcataacgtgagaagtaagagtgatcctataatgctg
ctccgagagagaattatcagcaacaacctcagcaatattgaagaattgaaagaaattgat
gcagatgtgaagaaagaggtggaggacgcagctcagtttgctacgactgatccagaacca
gctgtggaagatatagccaattacctctaccaccaagatccaccttttgaagtccgtggt
gcacataagtggctcaagtataagtcccacagttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (3)   
   Pfam (3)   
All databases (54)   

Download RDF
KEGG   Mus musculus (mouse): 68263
Entry
68263             CDS       T01002                                 

Gene name
Pdhb, 2610103L06Rik, AL024199, C81408
Definition
(RefSeq) pyruvate dehydrogenase (lipoamide) beta
  KO
K00162  pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00020  Citrate cycle (TCA cycle)
mmu00620  Pyruvate metabolism
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu04066  HIF-1 signaling pathway
mmu04922  Glucagon signaling pathway
mmu05230  Central carbon metabolism in cancer
mmu05415  Diabetic cardiomyopathy
Module
mmu_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    68263 (Pdhb)
   00020 Citrate cycle (TCA cycle)
    68263 (Pdhb)
   00620 Pyruvate metabolism
    68263 (Pdhb)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    68263 (Pdhb)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    68263 (Pdhb)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    68263 (Pdhb)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    68263 (Pdhb)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     68263 (Pdhb)
SSDB
Motif
Pfam: Transket_pyr Transketolase_C
Other DBs
NCBI-GeneID: 68263
NCBI-ProteinID: NP_077183
MGI: 1915513
Ensembl: ENSMUSG00000021748
UniProt: Q9D051
Position
14; 14 A1
AA seq 359 aa
MAVVAGLVRGPLRQASGLLKRRFHRSAPAAVQLTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSAGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVMLENELMYGVAFELPAEAQSKDFLIPIGKAKIERQGTHITVV
AHSRPVGHCLEAAAVLSKEGIECEVINLRTIRPMDIEAIEASVMKTNHLVTVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKVLEDNSVPQVKDIIFAVKKTLNI
NT seq 1080 nt   +upstreamnt  +downstreamnt
atggcggtggtggctggtctggtgcggggacccttgcggcaggcttccgggctgctgaag
aggcgttttcaccgctcggcgcccgcagcggtgcagttgacagttcgtgaagctattaat
caaggtatggatgaagaactagaaagagatgaaaaagtttttctgcttggggaagaagtt
gcccagtatgacggtgcatacaaggttagcagaggcctgtggaagaaatacggtgacaag
aggatcatcgacacccccatctcagagatgggctttgctggaattgctgttggtgcagct
atggctgggttgcggcccatctgtgaatttatgaccttcaatttctctatgcaagctatt
gaccaggttataaactcagctgccaagacttactatatgtccgctggccttcagcctgtg
cccatagtattcagggggcccaatggcgcctcagcaggtgtagctgctcagcactcgcaa
tgctttgctgcatggtatgggcactgcccaggtttaaaagtggtcagcccctggaattcc
gaggatgcaaaaggacttattaaatcggccattcgtgataataacccagtggtaatgcta
gaaaatgaactgatgtatggagttgcatttgaacttcctgcagaagctcagtcaaaagat
ttcctgattcctattggaaaagccaaaattgaaaggcaagggacccacatcactgtagtt
gcccattcaagaccagtgggccactgcctagaagctgcagctgtattgtctaaggaggga
attgaatgtgaggtaataaatctgcgcaccatcagaccaatggacatcgaagccatagaa
gccagtgtgatgaagacaaatcatctcgtgactgtggaaggaggctggccacaatttgga
gtaggagctgagatttgtgccagaattatggaaggccctgcattcaacttccttgatgcc
cctgccgtgcgtgtcactggtgctgatgtccctatgccttacgcaaaggtcctagaagac
aactccgtacctcaggtcaaagacatcatatttgcagtaaagaagactctgaacatctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (34)   
   RefSeq(nuc) (2)   
   GenBank (16)   
   EMBL (16)   
Protein domain (2)   
   Pfam (2)   
All databases (78)   

Download RDF
DBGET integrated database retrieval system