Entry |
|
Gene name |
Prkaca, C, P, PKCD, Pk, Pkaca
|
Definition |
(RefSeq) protein kinase, cAMP dependent, catalytic, alpha
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KO |
|
Organism |
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Pathway |
mmu04213 | Longevity regulating pathway - multiple species |
mmu04261 | Adrenergic signaling in cardiomyocytes |
mmu04270 | Vascular smooth muscle contraction |
mmu04723 | Retrograde endocannabinoid signaling |
mmu04750 | Inflammatory mediator regulation of TRP channels |
mmu04914 | Progesterone-mediated oocyte maturation |
mmu04919 | Thyroid hormone signaling pathway |
mmu04923 | Regulation of lipolysis in adipocytes |
mmu04925 | Aldosterone synthesis and secretion |
mmu04927 | Cortisol synthesis and secretion |
mmu04928 | Parathyroid hormone synthesis, secretion and action |
mmu04935 | Growth hormone synthesis, secretion and action |
mmu04961 | Endocrine and other factor-regulated calcium reabsorption |
mmu04962 | Vasopressin-regulated water reabsorption |
mmu05163 | Human cytomegalovirus infection |
mmu05166 | Human T-cell leukemia virus 1 infection |
|
Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
18747 (Prkaca)
04014 Ras signaling pathway
18747 (Prkaca)
04310 Wnt signaling pathway
18747 (Prkaca)
04340 Hedgehog signaling pathway
18747 (Prkaca)
04371 Apelin signaling pathway
18747 (Prkaca)
04020 Calcium signaling pathway
18747 (Prkaca)
04024 cAMP signaling pathway
18747 (Prkaca)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
18747 (Prkaca)
09143 Cell growth and death
04114 Oocyte meiosis
18747 (Prkaca)
09144 Cellular community - eukaryotes
04530 Tight junction
18747 (Prkaca)
04540 Gap junction
18747 (Prkaca)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
18747 (Prkaca)
04062 Chemokine signaling pathway
18747 (Prkaca)
09152 Endocrine system
04911 Insulin secretion
18747 (Prkaca)
04910 Insulin signaling pathway
18747 (Prkaca)
04922 Glucagon signaling pathway
18747 (Prkaca)
04923 Regulation of lipolysis in adipocytes
18747 (Prkaca)
04912 GnRH signaling pathway
18747 (Prkaca)
04913 Ovarian steroidogenesis
18747 (Prkaca)
04915 Estrogen signaling pathway
18747 (Prkaca)
04914 Progesterone-mediated oocyte maturation
18747 (Prkaca)
04921 Oxytocin signaling pathway
18747 (Prkaca)
04926 Relaxin signaling pathway
18747 (Prkaca)
04935 Growth hormone synthesis, secretion and action
18747 (Prkaca)
04918 Thyroid hormone synthesis
18747 (Prkaca)
04919 Thyroid hormone signaling pathway
18747 (Prkaca)
04928 Parathyroid hormone synthesis, secretion and action
18747 (Prkaca)
04916 Melanogenesis
18747 (Prkaca)
04924 Renin secretion
18747 (Prkaca)
04925 Aldosterone synthesis and secretion
18747 (Prkaca)
04927 Cortisol synthesis and secretion
18747 (Prkaca)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
18747 (Prkaca)
04270 Vascular smooth muscle contraction
18747 (Prkaca)
09154 Digestive system
04970 Salivary secretion
18747 (Prkaca)
04971 Gastric acid secretion
18747 (Prkaca)
04976 Bile secretion
18747 (Prkaca)
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
18747 (Prkaca)
04961 Endocrine and other factor-regulated calcium reabsorption
18747 (Prkaca)
09156 Nervous system
04724 Glutamatergic synapse
18747 (Prkaca)
04727 GABAergic synapse
18747 (Prkaca)
04725 Cholinergic synapse
18747 (Prkaca)
04728 Dopaminergic synapse
18747 (Prkaca)
04726 Serotonergic synapse
18747 (Prkaca)
04720 Long-term potentiation
18747 (Prkaca)
04723 Retrograde endocannabinoid signaling
18747 (Prkaca)
09157 Sensory system
04740 Olfactory transduction
18747 (Prkaca)
04742 Taste transduction
18747 (Prkaca)
04750 Inflammatory mediator regulation of TRP channels
18747 (Prkaca)
09149 Aging
04211 Longevity regulating pathway
18747 (Prkaca)
04213 Longevity regulating pathway - multiple species
18747 (Prkaca)
09159 Environmental adaptation
04713 Circadian entrainment
18747 (Prkaca)
04714 Thermogenesis
18747 (Prkaca)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
18747 (Prkaca)
05205 Proteoglycans in cancer
18747 (Prkaca)
05203 Viral carcinogenesis
18747 (Prkaca)
09164 Neurodegenerative disease
05012 Parkinson disease
18747 (Prkaca)
05020 Prion disease
18747 (Prkaca)
09165 Substance dependence
05030 Cocaine addiction
18747 (Prkaca)
05031 Amphetamine addiction
18747 (Prkaca)
05032 Morphine addiction
18747 (Prkaca)
05034 Alcoholism
18747 (Prkaca)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
18747 (Prkaca)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
18747 (Prkaca)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
18747 (Prkaca)
05163 Human cytomegalovirus infection
18747 (Prkaca)
05165 Human papillomavirus infection
18747 (Prkaca)
09174 Infectious disease: parasitic
05146 Amoebiasis
18747 (Prkaca)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
18747 (Prkaca)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:mmu01001]
18747 (Prkaca)
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:mmu03019]
18747 (Prkaca)
03036 Chromosome and associated proteins [BR:mmu03036]
18747 (Prkaca)
Enzymes [BR:mmu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.11 cAMP-dependent protein kinase
18747 (Prkaca)
Protein kinases [BR:mmu01001]
Serine/threonine kinases: AGC group
PKA family
18747 (Prkaca)
Messenger RNA biogenesis [BR:mmu03019]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
18747 (Prkaca)
Chromosome and associated proteins [BR:mmu03036]
Eukaryotic type
Centrosome formation and ciliogenesis proteins
Kinases and associated factors
18747 (Prkaca)
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SSDB |
|
Motif |
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Other DBs |
|
Structure |
PDB: |
Position |
8; 8 C2
|
AA seq |
351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVML
VKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF |
NT seq |
1056 nt +upstreamnt +downstreamnt
atgggcaacgccgccgccgccaagaagggcagcgagcaggagagcgtgaaagagttccta
gccaaagccaaggaagatttcctgaaaaaatgggagaccccttctcagaatacagcccag
ttggatcagtttgatagaatcaagacccttggcaccggctcctttgggcgagtgatgctg
gtgaagcacaaggagagtgggaaccactacgccatgaagatcttagacaagcagaaggtg
gtgaagctaaagcagatcgagcacactctgaatgagaagcgcatcctgcaggccgtcaac
ttcccgttcctggtcaaacttgaattctccttcaaggacaactcaaacctgtacatggtc
atggagtatgtagctggtggcgagatgttctcccacctacggcggattggaaggttcagc
gagccccatgcccgtttctacgcggcgcagatcgtcctgacctttgagtatctgcactcc
ctggacctcatctaccgggacctgaagcccgagaatcttctcatcgaccagcagggctat
attcaggtgacagacttcggttttgccaagcgtgtgaaaggccgtacttggaccttgtgt
gggacccctgagtacttggcccccgagattatcctgagcaaaggctacaacaaggctgtg
gactggtgggctctcggagtcctcatctacgagatggctgctggttacccacccttcttc
gctgaccagcctatccagatctatgagaaaatcgtctctgggaaggtgcggttcccatcc
cacttcagctctgacttgaaggacctgctgcggaaccttctgcaggtggatctcaccaag
cgctttgggaacctcaagaacggggtcaatgacatcaagaaccacaagtggtttgccacg
actgactggattgccatctatcagagaaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacgagtaactttgacgactatgaggaggaagagatccgggtctccatc
aatgagaagtgtggcaaggagtttactgagttttag |