KEGG   Mus musculus (mouse): 18802Help
Entry
18802             CDS       T01002                                 

Gene name
Plcd4, 4921507K24Rik
Definition
(RefSeq) phospholipase C, delta 4
  KO
K05857  phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00562  Inositol phosphate metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04070  Phosphatidylinositol signaling system
mmu04919  Thyroid hormone signaling pathway
mmu04933  AGE-RAGE signaling pathway in diabetic complications
Module
mmu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    18802 (Plcd4)
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    18802 (Plcd4)
   04070 Phosphatidylinositol signaling system
    18802 (Plcd4)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    18802 (Plcd4)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    18802 (Plcd4)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     18802 (Plcd4)
Membrane trafficking [BR:mmu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    18802 (Plcd4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    18802 (Plcd4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PI-PLC-X PI-PLC-Y EF-hand_like C2 EF-hand_10 PH EF-hand_7 EF-hand_6 PH_12 EF-hand_1 EF-hand_5 GDPD Wap1
Motif
Other DBs
NCBI-GeneID: 18802
NCBI-ProteinID: NP_683739
MGI: 107469
Ensembl: ENSMUSG00000026173
Vega: OTTMUSG00000021578
UniProt: Q8K3R3
Position
1 C3; 1 38.54 cM
AA seq 807 aa AA seqDB search
MTSQIQDLLATDQDLLLMQEGTMMRKVRTKSWKKLRYFRLQNDGMTVWHGSQPESMPKPT
FSISDVERIRKGQDSELLRYLVEEFPLEQGFTVVFHGRRPNLDLVANSVEEAQIWMRGLQ
LLVDLVASMDHQEQMDQMLNEWFQQADRNQDGRMSFREAQRLLLLMNVEMDEEYAFSLFQ
EADVTQSDDLGSEEFVQFYKALTKRTEIEEIFEDFSSDKQKLTLLEFVDFLRKEQKEKDH
APDLALELIDRYEPSENGRLLHVLSKDGFLKYLCSKDGNIFNSDCLPIYQDMTQPLSHYY
INSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYHGHTLTSRILF
KDVLATLAQYAFQSSDYPLILSLENHCTWEQQRTMAHHLTEILGEQLLRNTLEGLLVDSM
PSPEQLRGKILVKGKKLRTIEVDKEEEEEEEEEELEKDEGPDLDPASPELDTQPQPETQG
QAAGNKKERKKKVMKCPMSCLLICGHVMAQAPSSIPESILLSKQFLLLSSTTIMCPDLSA
LVVYLRTVPFCSFTHSKENYHIYDISSFSESKAKNLIKEAGNEFVQHNARQLCRVYPSGL
RTDSSNFNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGGSGYVLKPEFLRDTQSSF
NPERPISLYKAQILVVQVISGQQLPKVDKTKETTVVDPLVKVELYGVPEDTKEQETSHVE
NNGINPYWGETFYFRLQVPELAMLRFVVKDYSRKSRNNFIGQYTLPWTCMKQGYRHVSLL
SRDGTSLNPASIFVYTCMQEDLDMDEP
NT seq 2424 nt NT seq  +upstreamnt  +downstreamnt
atgacatctcagattcaagacctactagccactgatcaggacctgctgctgatgcaagaa
ggcacaatgatgcgcaaggtgaggaccaaaagctggaagaagctaagatacttcagactt
cagaatgacggcatgacagtctggcatggaagtcaaccagaaagcatgcccaagcccact
ttttcgatctctgatgtggagaggatacgtaaggggcaggattctgagttgttgcgctat
ctggtggaggagtttcccctggagcaagggttcaccgttgtctttcatgggcgccgcccc
aacctggacctagtggccaacagtgttgaagaggcccagatttggatgcgaggactccag
ctgttggtggatcttgttgccagcatggaccaccaggagcaaatggatcaaatgttgaat
gagtggttccagcaagcagacagaaaccaggatggccggatgagtttcagagaagctcaa
cggctgctgcttctgatgaacgtggaaatggatgaagagtacgccttcagtcttttccag
gaggcagatgttacccagtctgatgatctggggtcggaagaatttgtacagttctataag
gccctgactaagcgcactgagattgaagaaatatttgaggacttctcatctgacaaacag
aagctgaccttgctggaatttgtggatttccttagaaaggaacagaaagaaaaagaccat
gctcctgacctcgctctggaactcattgaccgctatgagccttctgagaatggccgattg
ctgcatgtgctgagcaaggatggcttcctcaagtacctctgctcgaaggatggaaacatc
ttcaacagtgactgcctccctatctaccaggatatgactcagcctctgagccactactac
attaactcttctcacaacacctacctagtgggggaccagctttgcggccagagcagcgtt
gaaggatacatacgggccttgaaacgggggtgccgctgtgtggaggtggacacgtgggat
ggacctgatggagagcctgttgtttatcatgggcataccctgacctctcgcatcctattc
aaagatgtgttggcaactctcgcgcaatatgccttccagtcatcagactaccctctcatc
ttgtctctggaaaaccactgcacctgggaacagcagaggaccatggcacaccatctgacc
gagatcctgggagagcagctgctgaggaacaccctagagggattgctggttgacagcatg
ccctcgccagagcagcttcgggggaagatcttggtgaaaggaaagaagttaagaacaatt
gaagttgacaaggaagaagaagaagaagaagaagaagaagagctggagaaagatgagggg
ccagatctggacccagcctcccctgagttggacactcaacctcagcctgagacccagggg
caggccgctgggaacaagaaggagaggaagaagaaggttatgaagtgtccgatgtcttgt
ctgcttatctgtggtcatgttatggcccaggctcctagttccattcctgagtccattctc
ttgtcaaagcagtttcttctcctgagttccacaaccatcatgtgcccagacctatctgcc
ctggttgtctacttgaggactgtccccttctgcagcttcactcattccaaagaaaactac
cacatctatgacatttcatccttttctgagtccaaggccaagaacctcatcaaggaggca
ggcaacgagtttgtacagcacaatgccagacagttatgccgcgtgtatcccagtggtctg
aggacagattcatccaactttaacccccaggaacactggaatgtaggctgccagatggtg
gctatgaatatgcagactgcaggaagtgcaatggatatctgtgatgggctcttccgccag
aatggtggctctggctatgtgctgaagccagaattcctgagagatacccagagttcattc
aatcctgagaggccaattagtctttataaggcccagatccttgtagtccaggtgatcagt
ggccaacaactccccaaagtggataaaaccaaagagacaaccgttgtggatccactggtg
aaagtagagctctatggtgttcctgaagacacaaaggagcaagagaccagccatgtggag
aacaatggtattaatccatactggggggagactttctatttccggctccaggtacctgaa
cttgctatgttgcgttttgtggtaaaggattatagcaggaaatcccgaaataactttatt
ggccaatacaccctaccttggacctgtatgaaacaaggctaccgacatgtatccttgctc
tccagagatggcactagcctcaatccagcttccatctttgtatacacctgcatgcaggaa
gacctggatatggatgagccctga

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