KEGG   Mus musculus (mouse): 18976
Entry
18976             CDS       T01002                                 

Gene name
Pomc, ACT, ACTH, BE, Beta-LPH, Clip, Gamma-LPH, Npp, PO, Pomc-1, Pomc1, alp, alph, alpha-MSH, alphaMSH, beta-M, beta-MSH, gamma-, gamma-MSH
Definition
(RefSeq) pro-opiomelanocortin-alpha
  KO
K05228  proopiomelanocortin
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04024  cAMP signaling pathway
mmu04080  Neuroactive ligand-receptor interaction
mmu04915  Estrogen signaling pathway
mmu04916  Melanogenesis
mmu04920  Adipocytokine signaling pathway
mmu04925  Aldosterone synthesis and secretion
mmu04927  Cortisol synthesis and secretion
mmu04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    18976 (Pomc)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    18976 (Pomc)
 09150 Organismal Systems
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    18976 (Pomc)
   04915 Estrogen signaling pathway
    18976 (Pomc)
   04916 Melanogenesis
    18976 (Pomc)
   04925 Aldosterone synthesis and secretion
    18976 (Pomc)
   04927 Cortisol synthesis and secretion
    18976 (Pomc)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    18976 (Pomc)
SSDB
Motif
Pfam: ACTH_domain NPP Op_neuropeptide
Other DBs
NCBI-GeneID: 18976
NCBI-ProteinID: NP_001265510
MGI: 97742
Ensembl: ENSMUSG00000020660
UniProt: P01193
Position
12 A1.1; 12 1.99 cM
AA seq 235 aa
MPRFCYSRSGALLLALLLQTSIDVWSWCLESSQCQDLTTESNLLACIRACKLDLSLETPV
FPGNGDEQPLTENPRKYVMGHFRWDRFGPRNSSSAGSAAQRRAEEEAVWGDGSPEPSPRE
GKRSYSMEHFRWGKPVGKKRRPVKVYPNVAENESAEAFPLEFKRELEGERPLGLEQVLES
DAEKDDGPYRVEHFRWSNPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ
NT seq 708 nt   +upstreamnt  +downstreamnt
atgccgagattctgctacagtcgctcaggggccctgttgctggccctcctgcttcagacc
tccatagatgtgtggagctggtgcctggagagcagccagtgccaggacctcaccacggag
agcaacctgctggcttgcatccgggcttgcaaactcgacctctcgctggagacgcccgtg
tttcctggcaacggagatgaacagcccctgactgaaaacccccggaagtacgtcatgggt
cacttccgctgggaccgcttcggccccaggaacagcagcagtgctggcagcgcggcgcag
aggcgtgcggaggaagaggcggtgtggggagatggcagtccagagccgagtccacgcgag
ggcaagcgctcctactccatggagcacttccgctggggcaagccggtgggcaagaaacgg
cgcccggtgaaggtgtaccccaacgttgctgagaacgagtcggcggaggcctttccccta
gagttcaagagggagctggaaggcgagcggccattaggcttggagcaggtcctggagtcc
gacgcggagaaggacgacgggccctaccgggtggagcacttccgctggagcaacccgccc
aaggacaagcgttacggtggcttcatgacctccgagaagagccagacgcccctggtgacg
ctcttcaagaacgccatcatcaagaacgcgcacaagaagggccagtga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (39)   
   RefSeq(nuc) (5)   
   GenBank (17)   
   EMBL (17)   
Protein domain (3)   
   Pfam (3)   
All databases (72)   

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