KEGG   Mus musculus (house mouse): 19014
Entry
19014             CDS       T01002                                 
Symbol
Med1, CRSP210, DRIP205, PBP, Pparbp, TRAP220, TRIP-2, l11Jus15
Name
(RefSeq) mediator complex subunit 1
  KO
K15144  mediator of RNA polymerase II transcription subunit 1
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu01522  Endocrine resistance
mmu04919  Thyroid hormone signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    19014 (Med1)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    19014 (Med1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mmu03021]
    19014 (Med1)
Transcription machinery [BR:mmu03021]
 Eukaryotic type
  RNA polymerase II system
   Mediator complex
    Middle
     19014 (Med1)
SSDB
Motif
Pfam: Med1 DUF34_NIF3
Other DBs
NCBI-GeneID: 19014
NCBI-ProteinID: NP_001073587
MGI: 1100846
Ensembl: ENSMUSG00000018160
UniProt: Q925J9
Structure
Position
11:complement(98042980..98084121)
AA seq 1575 aa
MKAQGETEDSERLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVS
CLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQL
CDVKVAHHGENPVSCPELVQQLREKNFEEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL
EQDLSKMAIMYWKATNAAPLDKILHGSVGYLTPRSGGHLMNMKYYASPSDLLDDKTASPI
ILHEKNVPRSLGMNASVTIEGTSAMYKLPIAPLIMGSHPADNKWTPSFSAVTSANSVDLP
ACFFLKFPQPIPVSKAFVQKLQNCTGIPLFETPPTYLPLYELITQFELSKDPDPLPLNHN
MRFYAALPGQQHCYFLNKDAPLPDGQSLQGTLVSKITFQHPGRVPLILNMIRHQVAYNTL
IGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLY
KGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNL
PPASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQ
NPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTL
YGSSPLERQNSSSGSPRMEMCSGSNKAKKKKSSRVPPDKPKHQTEDDFQRELFSMDVDSQ
NPMFDVSMTADALDTPHITPAPSQCSTPPATYPQPVSHPQPSIQRMVRLSSSDSIGPDVT
DILSDIAEEASKLPSTSDDCPPIGTPVRDSSSSGHSQSALFDSDVFQTNNNENPYTDPAD
LIADAAGSPNSDSPTNHFFPDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFAS
QALNTLGMPMLGGDNGEPKFKGSSQADTVDFSIISVAGKALGAADLMEHHSGSQSPLLTT
GELGKEKTQKRVKEGNGTGASSGSGPGSDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGK
SPSHSSSNRPFTPPTSTGGSKSPGSSGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSH
SQYTSSGSVSSSGSKSHHSHSSSSSSLASASTSGKVKSSKSEGSSSSKLSGSMYASQGSS
GSSQSKNSSQTGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSISKPNISPSHSRP
PGGSDKLASPMKPVPGTPPSSKAKSPISSGSSGSHVSGTSSSSGMKSSSGSASSGSVSQK
TPPASNSCTPSSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSG
PGGEDPIDSQMGASTNSSNHPMSSKHNTSGGEFQSKREKSDKDKSKVSASGGSVDSSKKT
SESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESGGDGLRPQIASSKNYGSPLISG
STPKHERGSPSHSKSPAYTPQNVDSESESGSSIAERSYQNSPSSEDGIRPLPEYSTEKHK
KHKKEKKKVRDKDRDKKKSHSMKPENWSKSPISSDPTASVTNNPILSADRPSRLSPDFMI
GEEDDDLMDVALIGN
NT seq 4728 nt   +upstreamnt  +downstreamnt
atgaaggctcagggggaaaccgaggactcagagaggctgagtaagatgagctccctcctg
gaacggctccatgcaaaatttaaccagaacagaccttggagtgaaaccattaagcttgtg
cgtcaagtaatggagaagagggtcgtaatgagttctggagggcatcagcatttggtcagc
tgtttggagacattgcagaaggctctcaaagtaacatctttgccagcaatgactgatcgt
ttggaatctatagccagacagaatggactgggctctcacctcagtgccagtggcactgag
tgttacatcacgtcagatatgttctatgtggaagtgcagttagatcctgcaggacagctt
tgtgatgtcaaagtggctcaccatggggagaatcctgtgagctgtccagagcttgtacag
cagttaagggaaaagaattttgaggaattttccaagcatcttaagggtcttgttaatctg
tataatctcccaggggacaacaaactgaagactaaaatgtatctggctctccaatcctta
gaacaggacctttctaaaatggctattatgtactggaaggcaaccaacgccgctcccttg
gataagattcttcatggaagtgttggttatctcaccccgcggagtgggggtcatttaatg
aatatgaaatactatgcctctccatctgacctgctggatgataagactgcctctcctatc
attttgcatgaaaagaatgttcctcggtctttgggaatgaatgcctcagtgacaattgaa
ggaacctctgctatgtacaaactcccaattgccccattaattatggggtcacacccagct
gacaacaaatggaccccttctttctccgcagtcactagtgccaacagtgttgatcttcct
gcgtgtttcttcttgaaatttccccagccaattccagtatctaaagcatttgttcagaaa
ctgcaaaattgcacaggaatcccgttgtttgagactccgcccacttacctgcccctgtat
gaactcatcactcagtttgagctgtcaaaggatcctgaccctttacctttgaatcacaac
atgcgattttacgctgctcttccaggtcagcagcactgctattttctcaataaagatgct
cctcttcctgatggtcagagcctgcagggaacactggtcagcaaaatcaccttccagcac
cctggccgagttcctcttatcttgaatatgatcagacaccaagtggcctataacactcta
attggaagctgtgtcaaaagaactattttaaaagaagattctcctgggctcctccagttt
gaagtgtgtcctctctcagaatctcgcttcagtgtatcttttcagcaccctgtgaatgac
tcccttgtgtgtgtggtgatggatgtgcaagactcaacacatgtgagctgtaaactctac
aaggggctgtcagatgcactaatctgtacagacgacttcattgccaaagttgttcaaaga
tgtatgtccattcctgtgacgatgagggctattcggaggaaggctgaaaccatacaggct
gacaccccagcactgtctctcattgcagagacagttgaagacatggtgaaaaagaacctg
cccccggctagcagcccagggtatggcatgaccacaggcaacaacccaatgagtggtacc
actacaccaaccaacacctttccggggggtcccattaccaccttgtttaatatgagcatg
agcatcaaagatcggcatgagtcggtgggccatggggaggacttcagcaaggtgtctcag
aacccaattcttaccagtttgttgcaaatcacagggaacggggggtctaccattggctcg
agtccgacccctcctcatcacacgccgccacctgtctcttcgatggccggcaacaccaag
aaccacccgatgctcatgaaccttcttaaagataaccctgcccaggatttctcaaccctt
tatggaagcagccctttagaaaggcagaactcctcttccggatcaccccggatggaaatg
tgctcggggagcaacaaggccaagaagaagaagtcgtcaagagtcccacctgacaaaccc
aagcaccagactgaagacgatttccagagggagctcttttccatggatgtcgactcacag
aaccctatgtttgacgtcagcatgaccgctgacgcgctggatacacctcatatcacccca
gctccaagccagtgtagcactcccccagcaacgtacccacagccagtgtctcacccccag
cccagtattcagaggatggtccgactgtccagttcagacagcattggcccagatgtaact
gatattctttcagatattgccgaagaagcttcaaagcttcccagcacgagtgatgactgc
ccaccaattggcacccctgttcgagattcctcaagttctgggcattctcagagtgccctc
tttgattctgatgtctttcaaactaataataatgaaaatccatacactgatccagctgac
cttattgcagatgctgctggaagccccaatagtgattctcctaccaatcattttttccct
gatggagtagatttcaatcctgatttgttgaacagccaaagccaaagtggttttggagag
gagtattttgatgaaagtagtcagagtggggataatgatgatttcaaaggatttgcatct
caggcattaaatacattggggatgccaatgcttggaggtgacaatggggagccaaaattt
aagggcagcagccaggctgacacggtggacttcagtattatatcagtagccggtaaggct
ttgggtgctgcagatctgatggagcaccacagtgggagtcagagtcctttactgaccact
ggagaattagggaaagaaaaaactcaaaagagggtgaaggaaggcaacggcacaggtgct
agcagtggatcaggtccagggtcagacagcaagccaggcaagcgcagccgcactccctcc
aatgatgggaagagcaaggataagcctccaaagcggaagaaggcagacactgaggggaag
tccccatctcacagttcttctaatagacctttcaccccacctaccagcacgggtgggtcc
aaatccccaggcagttcaggacgatctcagacgcccccaggtgttgccaccccgcccatt
cccaagattaccattcagattcctaaagggacagtgatggtgggcaagccctcctctcac
agtcagtacactagcagtggttctgtgtcttcctctggcagcaaaagccaccatagtcat
tcttcctcctcctcttccttagcttctgcttccacctcaggcaaggtgaaaagcagtaaa
tctgaaggctcatcaagttccaagctcagtggcagtatgtatgctagccaagggtcttct
ggatccagccagtccaaaaattcatctcagactggggggaagccaggctcctctcccatt
accaaacatggactgagcagtgggtccagcagtaccaagatgaaacctcaaggcaagcca
tcctcccttatgaacccttctataagtaagccaaacatatccccttcccattcaaggcct
cccggaggctcagataagcttgcctctccaatgaagcctgttcctggaacccccccatcc
tctaaagccaagtcccctatcagttcaggttccagtggttctcatgtgtcaggaactagt
tcaagctctggtatgaagtcatcttcagggtcagcatcctcaggctcagtgtctcaaaaa
acccctccagcatctaattcttgtacaccatcttcctcttcgttttcctcaagtggttct
tccatgtcatcctctcagaatcaacatggcagttccaaagggaaatctcccagtaggaat
aagaagccttccttgacagctgtcatagataaattgaagcatggggtggttaccagtggg
cctgggggtgaggatccaatagacagtcagatgggcgcaagcacaaattcttctaaccat
cccatgtcctccaaacataacacgtcaggaggggagttccagagcaaacgtgagaaaagt
gataaagacaaatccaaggtctctgcttctggggggtcagtggattcctctaagaagact
tcagagtcaaaaaatgtggggagcacgggggtggcaaaaatcattatcagcaagcacgac
ggaggctccccgagcatcaaagccaaagtgacgctacagaaacctggagaaagtggtgga
gatgggctcaggccacagatagcctcatcaaagaactatggctctccacttatcagtggt
tccactccaaagcacgaacggggttctcccagccacagtaagtcgccagcatatacacca
cagaatgtggacagtgaaagtgagtcaggctcctccatagcagagagatcctaccagaac
agtcccagctcagaggatggtatccgaccacttccagagtacagcactgagaagcataag
aagcacaaaaaggaaaagaagaaagtcagagacaaagacagagacaagaagaagtctcac
agcatgaagccagagaactggtcgaaatcccccatttcttcagatccgacggcgtctgtg
acaaataaccctatcttatctgcagacaggccttctaggctcagccctgacttcatgatt
ggggaggaagatgatgatctcatggatgtggccctgattggcaattag

  All links  
Gene (40)   
   RefGene (35)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (40)   
   RefSeq(nuc) (10)   
   GenBank (15)   
   EMBL (15)   
3D Structure (3)   
   PDB (3)   
Protein domain (2)   
   Pfam (2)   
All databases (94)   

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