Entry |
|
Gene name |
Psma1, C2, HC2, Pro, Pros-30, alpha-type
|
Definition |
(RefSeq) proteasome subunit alpha 1
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KO |
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Organism |
|
Pathway |
mmu05022 | Pathways of neurodegeneration - multiple diseases |
|
Brite |
KEGG Orthology (KO) [BR:mmu00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03050 Proteasome
26440 (Psma1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
26440 (Psma1)
05012 Parkinson disease
26440 (Psma1)
05014 Amyotrophic lateral sclerosis
26440 (Psma1)
05016 Huntington disease
26440 (Psma1)
05017 Spinocerebellar ataxia
26440 (Psma1)
05020 Prion disease
26440 (Psma1)
05022 Pathways of neurodegeneration - multiple diseases
26440 (Psma1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:mmu01002]
26440 (Psma1)
09182 Protein families: genetic information processing
03051 Proteasome [BR:mmu03051]
26440 (Psma1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:mmu04147]
26440 (Psma1)
Enzymes [BR:mmu01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.25 Threonine endopeptidases
3.4.25.1 proteasome endopeptidase complex
26440 (Psma1)
Peptidases and inhibitors [BR:mmu01002]
Threonine peptidases
Family T1: proteasome family
26440 (Psma1)
Proteasome [BR:mmu03051]
Eukaryotic proteasome
Core particles (20S proteasome)
alpha type subunits
26440 (Psma1)
Exosome [BR:mmu04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
26440 (Psma1)
|
SSDB |
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Motif |
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Other DBs |
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Structure |
PDB: |
Position |
7 F1; 7 59.32 cM
|
AA seq |
263 aa
MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ
KKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPT
QRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM
ECNLDELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLEERP
QRKAQPSQAAEEPAEKADEPMEH |
NT seq |
792 nt +upstreamnt +downstreamnt
atgtttcgaaaccagtatgacaatgatgtcactgtttggagccctcagggcaggattcat
caaattgaatatgcaatggaagctgttaagcaaggttcagcaacagttggtctaaaatca
aaaacgcacgcagtgctggttgcactgaagagagcacagtcagagcttgccgctcaccag
aagaaaattctccatgttgacaaccatattggtatctcaattgcgggtctaactgctgat
gccagactgttatgcaactttatgcgccaggagtgtttggattccagatttgtgtttgac
agaccacttcctgtgtctcgtcttgtgtctctaattggaagcaaaacccagatcccaaca
cagcgatatggccggaggccgtatggtgttgggctgctcattgctggttatgatgatatg
ggccctcatattttccaaacctgtccatctgctaactattttgactgcagagctatgtct
attggagcccgttctcaatcagctcgtacttacctggagagacatatgtctgaatttatg
gagtgcaatttggatgaactggttaaacatggtctgcgtgccttaagagaaacactccct
gcagagcaggacctgaccacaaagaatgtttccattggaatcgttggtaaagacttggaa
tttacaatctacgatgatgatgatgtatctccattcctggatggtcttgaagaaagacca
cagagaaaagcacagccttcacaggctgctgaggaacctgcagaaaaagccgatgaacca
atggaacattaa |