| Entry |
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| Gene name |
Ptk2b, CADTK, CAKB, CAKbe, CAKbeta, E430023O05Rik, FADK2, FAK2, PYK, PYK2, Raf, Raftk
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| Definition |
(RefSeq) PTK2 protein tyrosine kinase 2 beta
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| KO |
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| Organism |
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| Pathway |
| mmu04072 | Phospholipase D signaling pathway |
| mmu04650 | Natural killer cell mediated cytotoxicity |
| mmu04670 | Leukocyte transendothelial migration |
| mmu05163 | Human cytomegalovirus infection |
| mmu05170 | Human immunodeficiency virus 1 infection |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
19229 (Ptk2b)
04072 Phospholipase D signaling pathway
19229 (Ptk2b)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
19229 (Ptk2b)
04670 Leukocyte transendothelial migration
19229 (Ptk2b)
04062 Chemokine signaling pathway
19229 (Ptk2b)
09152 Endocrine system
04912 GnRH signaling pathway
19229 (Ptk2b)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
19229 (Ptk2b)
05161 Hepatitis B
19229 (Ptk2b)
05163 Human cytomegalovirus infection
19229 (Ptk2b)
09171 Infectious disease: bacterial
05135 Yersinia infection
19229 (Ptk2b)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:mmu01001]
19229 (Ptk2b)
Enzymes [BR:mmu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
19229 (Ptk2b)
Protein kinases [BR:mmu01001]
Non-receptor tyrosine kinases
FAK family
19229 (Ptk2b)
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| SSDB |
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| Motif |
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| Other DBs |
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| Position |
14 D1; 14 34.36 cM
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| AA seq |
1009 aa
MSGVSEPLSRVKVGTLRRPEGPPEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
CTVQTEIQEIITSILLSGRIGPNIQLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDTKPTCLA
EFKQIKSIRCLPLEETQAVLQLGIEGAPQSLSIKTSSLAEAENMADLIDGYCRLQGEHKG
SLIMHAKKDGEKRNSLPQIPTLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGV
AREEVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTQDNKEKFMSEAVIMKN
LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVPTLVLYTLQICKAMAYL
ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTR
CWDYDPSDRPRFTELVCSLSDIYQMEKDIAIEQERNARYRPPKILEPTTFQEPPPKPSRP
KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
EEDFIRPSSREEAQQLWEAEKIKMKQVLERQQKQMVEDSQWLRREERCLDPMVYMNDKSP
LTPEKEAGYTEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYHNVMTLVEAVLELKNKLGQ
LPPEDYVVVVKNVGLNLRKLIGSVDDLLPSLPASSRTEIEGTQKLLNKDLAELINKMKLA
QQNAVTSLSEDCKRQMLTASHTLAVDAKNLLDAVDQAKVVANLAHPPAE |
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| NT seq |
3030 nt +upstreamnt +downstreamnt
atgtccggggtgtctgagcccttgagccgtgtaaaagtgggcactttacgccggcctgag
ggccccccagagcccatggtggtggtaccagtggatgtggagaaggaagacgtgcgcatc
ctcaaggtctgcttctacagcaacagcttcaacccagggaagaacttcaagcttgtcaaa
tgcacagtgcagacagagatccaggagatcatcacctccatcctcctgagtgggcgaata
gggcccaacatccagctggctgaatgctatgggctgaggctgaagcacatgaagtcagac
gagatccactggctgcacccacagatgaccgtgggcgaagtgcaggacaagtatgaatgt
ctacacgtggaagctgagtggaggtatgaccttcaaatccgctacttgccggaagacttc
atggagagcctgaaagaagacaggaccacattgctgtacttttatcaacagctccggaat
gactacatgcaacgctacgccagcaaggtcagtgaaggcatggctctgcagctgggctgt
ctggagctcaggagattcttcaaggacatgccccacaatgcactggacaaaaagtccaac
tttgaactcctggaaaaagaagtcggtctggacctgtttttcccaaagcagatgcaggaa
aacttaaagcccaagcagttccggaagatgatccagcagaccttccagcagtatgcatca
ctccgggaggaagagtgtgtcatgaaattcttcaataccctagcgggctttgccaacatt
gaccaggagacctaccgctgcgaactcattcaaggatggaacattactgtggacctggtc
atcggccctaaaggcatccgtcagctgacaagtcaagatacaaagcccacctgcctggcc
gagtttaagcagatcaaatccatcaggtgcctcccattggaagagacccaggcagtcctg
cagctgggcatcgagggtgccccccagtccttgtctatcaaaacgtcgtccctggcagag
gctgagaacatggctgacctcatagatggctactgcaggctgcaaggagaacataagggc
tctctcatcatgcatgccaagaaagatggtgagaagaggaacagcctgcctcagatcccc
acactaaacctggaggctcggcggtcgcacctctcagaaagctgcagcatagagtcagac
atctatgcggagattcccgatgagaccctgcgaagaccaggaggtccacagtacggtgtt
gcccgtgaagaagtagttcttaaccgcattctgggtgaaggcttctttggggaggtctat
gaaggtgtctacacgaaccacaaaggggaaaaaattaatgtggccgtcaagacctgtaag
aaagactgtacccaggacaacaaggagaagttcatgagtgaggcagtgatcatgaagaat
cttgaccaccctcacatcgtgaagctgattggcatcattgaagaggaacccacctggatt
atcatggaactgtatccttatggggagctgggacactacctggaacgaaataaaaactcc
ctgaaggtacccactctggtcctgtacaccctacagatatgcaaagccatggcctatctg
gagagcatcaactgtgtgcacagggatattgctgtccggaacatcctggtggcctctcct
gagtgtgtgaagctgggggactttgggctctcccggtacattgaggacgaagactattac
aaagcctctgtgacccgtctacccatcaaatggatgtcccccgagtccatcaacttccgc
cgcttcacaaccgccagtgatgtctggatgtttgctgtatgcatgtgggagatcctcagc
tttgggaagcagcctttcttctggctcgaaaataaggatgtcatcggagtgctggagaaa
ggggacaggctgcccaagcccgaactctgtccgcctgtcctttacacactcatgactcgc
tgctgggactacgaccccagtgaccggccccgcttcacggagcttgtgtgcagcctcagt
gacatttatcagatggagaaggacattgccatagagcaagaaaggaatgctcgctaccga
ccccccaaaatattggagcctactacctttcaggaacccccacccaagcccagccggccc
aagtacagacctcctccacagaccaacctgctggctcctaagctgcagttccaggtccct
gagggtctgtgtgccagctctcctacgcttaccagccctatggagtatccatctccagtt
aactcgctacacaccccacctctccaccggcacaatgtcttcaagcgccacagcatgcgg
gaggaggacttcatccggcccagtagccgagaagaggcccagcagctctgggaggcagag
aagatcaagatgaagcaggtcctagaaagacagcagaagcagatggtggaagattcccag
tggctgaggcgagaggaaagatgcttggaccctatggtttatatgaatgacaagtcccca
ctgactccagagaaggaggccggctacacggagttcacagggcccccacagaaaccacct
cggctcggtgcacagtccattcagcccacagccaacctggacaggaccgatgacctcgtg
taccacaatgtcatgaccctggtggaggctgtgctggaactcaagaacaagcttggccag
ttgccccctgaggactatgtggtggtggtgaagaacgtggggctgaacctgcggaagctc
atcggcagtgtggacgatctcttgccctccttgccggcatcttcgaggacagagattgaa
gggacccagaaactgctcaacaaagacctggcagagctcatcaacaagatgaagttggct
cagcagaacgccgtgacgtccctgagtgaggactgcaagcggcagatgctcacagcgtcc
cataccctggctgtggatgccaagaacctgctggatgctgtggaccaagccaaggttgtg
gctaatctggcccacccgcctgcagagtga |
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