KEGG   Mus musculus (house mouse): 19246
Entry
19246             CDS       T01002                                 
Symbol
Ptpn1, PTP-1B, PTP-HA2, PTP1B
Name
(RefSeq) protein tyrosine phosphatase, non-receptor type 1
  KO
K05696  tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04520  Adherens junction
mmu04910  Insulin signaling pathway
mmu04931  Insulin resistance
mmu05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    19246 (Ptpn1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    19246 (Ptpn1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    19246 (Ptpn1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    19246 (Ptpn1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    19246 (Ptpn1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     19246 (Ptpn1)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    19246 (Ptpn1)
SSDB
Motif
Pfam: Y_phosphatase DSPc PTP-SAK Tc-R-P Y_phosphatase3 PTPlike_phytase Tudor_5
Other DBs
NCBI-GeneID: 19246
NCBI-ProteinID: NP_035331
MGI: 97805
Ensembl: ENSMUSG00000027540
UniProt: P35821 Q3TZW9
Position
2:167772670..167821305
AA seq 432 aa
MEMEKEFEEIDKAGNWAAIYQDIRHEASDFPCKVAKLPKNKNRNRYRDVSPFDHSRIKLH
QEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLK
CAQYWPQQEEKEMVFDDTGLKLTLISEDVKSYYTVRQLELENLTTKETREILHFHYTTWP
DFGVPESPASFLNFLFKVRESGSLSLEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKD
PSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSREDLD
LPPEHVPPPPRPPKRTLEPHNGKCKELFSSHQWVSEETCGDEDSLAREEGRAQSSAMHSV
SSMSPDTEVRRRMVGGGLQSAQASVPTEEELSSTEEEHKAHWPSHWKPFLVNVCMATLLA
TGAYLCYRVCFH
NT seq 1299 nt   +upstreamnt  +downstreamnt
atggagatggagaaggagttcgaggagatcgacaaggctgggaactgggcggctatttac
caggacattcgacatgaagccagcgacttcccatgcaaagtcgcgaagcttcctaagaac
aaaaaccggaacaggtaccgagatgtcagcccttttgaccacagtcggattaaattgcac
caggaagataatgactatatcaatgccagcttgataaaaatggaagaagcccagaggagc
tatattctcacccagggccctttaccaaacacatgtgggcacttctgggagatggtgtgg
gagcagaagagcaggggcgtggtcatgctcaaccgcatcatggagaaaggctcgttaaaa
tgtgcccagtattggccacagcaagaagaaaaggagatggtctttgatgacacaggtttg
aagttgacactaatctctgaagatgtcaagtcatattacacagtacgacagttggagttg
gaaaacctgactaccaaggagactcgagagatcctgcatttccactacaccacatggcct
gactttggagtccccgagtcaccggcttctttcctcaatttccttttcaaagtccgagag
tcaggctcactcagcctggagcatggccccattgtggtccactgcagcgccggcatcggg
aggtcagggaccttctgtctggctgacacctgcctcttactgatggacaagaggaaagac
ccatcttccgtggacatcaagaaagtactgctggagatgcgcaggttccgcatggggctc
atccagactgccgaccagctgcgcttctcctacctggctgtcatcgagggcgccaagttc
atcatgggcgactcgtcagtgcaggatcagtggaaggagctctcccgggaggatctagac
cttccacccgagcacgtgcccccacctccccggccacccaaacgcacactggagcctcac
aacgggaagtgcaaggagctcttctccagccaccagtgggtgagcgaggagacctgtggg
gatgaagacagcctggccagagaggaaggcagagcccagtcaagtgccatgcacagcgtg
agcagcatgagtccagacactgaagttaggagacggatggtgggtggaggtcttcaaagt
gctcaggcgtctgtccccaccgaggaagagctgtcctccactgaggaggaacacaaggca
cattggccaagtcactggaagcccttcctggtcaatgtgtgcatggccacgctcctggcc
accggcgcgtacttgtgctaccgggtgtgttttcactga

  All links  
Gene (13)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (90)   
   RefSeq(nuc) (4)   
   GenBank (43)   
   EMBL (43)   
Protein domain (7)   
   Pfam (7)   
All databases (117)   

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