KEGG   Mus musculus (house mouse): 20020
Entry
20020             CDS       T01002                                 
Symbol
Polr2a, 220kDa, Rpb1, Rpo2-1
Name
(RefSeq) polymerase (RNA) II (DNA directed) polypeptide A
  KO
K03006  DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03020  RNA polymerase
mmu03420  Nucleotide excision repair
mmu05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    20020 (Polr2a)
  09124 Replication and repair
   03420 Nucleotide excision repair
    20020 (Polr2a)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    20020 (Polr2a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mmu03021]
    20020 (Polr2a)
   03400 DNA repair and recombination proteins [BR:mmu03400]
    20020 (Polr2a)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.6  DNA-directed RNA polymerase
     20020 (Polr2a)
Transcription machinery [BR:mmu03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Core subunits
     20020 (Polr2a)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      20020 (Polr2a)
SSDB
Motif
Pfam: RNA_pol_Rpb1_1 RNA_pol_Rpb1_5 RNA_pol_Rpb1_2 RNA_pol_Rpb1_6 RNA_pol_Rpb1_7 RNA_pol_Rpb1_3 RNA_pol_Rpb1_R RNA_pol_Rpb1_4
Other DBs
NCBI-GeneID: 20020
NCBI-ProteinID: NP_001277997
MGI: 98086
Ensembl: ENSMUSG00000005198
UniProt: P08775
Position
11:complement(69624823..69649459)
AA seq 1970 aa
MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDP
RQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVD
SNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKG
HGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEP
RYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAA
HVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVD
FSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYII
RDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWS
TFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQD
TLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHI
NCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEM
GHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKA
HNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKIN
ISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHA
MGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGES
VEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMR
EDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKL
VIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAI
AHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLT
VFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMP
DFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIR
IMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKI
IITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALER
ELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLM
EAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTG
MFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPG
YSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSP
SYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP
TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS
YSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPT
SPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPASPKY
SPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTS
PKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN
NT seq 5913 nt   +upstreamnt  +downstreamnt
atgcacgggggtggccccccctccggggacagcgcatgcccgctgcgcaccatcaagaga
gtgcagttcggagtcctgagtccggatgaattgaagcggatgtctgtgacagagggtggt
atcaaatacccagaaacaacggagggaggtcgccccaaacttgggggactaatggatcca
cggcagggggtgattgagcggactggccgctgccaaacatgtgcaggaaacatgaccgag
tgtcctggccactttggccacatcgaattggccaaacctgtgtttcatgtgggcttcctg
gtgaagacaatgaaggttttgcgctgtgtctgcttcttctgctccaaactgcttgtagat
tctaataacccgaagattaaggacatcctggccaaatctaaggggcagccaaagaaacgg
cttacgcatgtctatgacctgtgcaagggcaaaaacatctgtgaaggtggagaggagatg
gacaacaagtttggtgtggagcagccggagggtgatgaggatctgaccaaagagaagggc
catggcggctgtgggcggtaccaaccccgaatccggcgctctggcctagagttgtatgct
gaatggaagcatgttaatgaggactctcaggagaaaaagatcttgctgagtccagaacga
gtgcatgaaatcttcaaacgcatctcagatgaggagtgttttgtgttgggcatggagcct
cgctatgcccggcctgagtggatgattgtcacagtgttgcctgtgcctcctctctcagtg
agacctgctgtggtgatgcagggttctgctcgaaaccaggatgatctgactcacaaactg
gctgacattgtgaagatcaacaatcagctgcggcggaacgagcagaatggtgcagctgcc
catgtcatagcagaagatgtaaaacttctccagttccatgtggccaccatggtggacaat
gaactgcccggcttaccccgtgccatgcagaagtctggccgtcccctcaagtccctgaag
caacggttgaagggcaaagaaggacgggttcgagggaatctaatgggcaagcgagtggac
ttctcagcccgcactgtcatcacccctgaccctaacctatccattgaccaagtgggtgtg
ccccgctccattgctgccaacatgacctttgcagagattgtcacacccttcaatattgac
agacttcaggaattagtacgcaggggaaacagccagtatccaggagccaagtacatcatc
cgcgataatggcgatcgaattgacttgcgtttccatcctaagcccagtgaccttcatctg
cagactggctataaggtggaacggcacatgtgtgatggggacattgttatcttcaatcgt
cagccaactttgcacaaaatgtccatgatggggcatcgggtccgaatcctcccctggtct
acttttcggttgaatcttagtgtgacaactccatacaatgcagactttgatggagatgag
atgaatttgcatctgccacagtctctggaaacacgggcagagatccaagagttggctatg
gtgcctcgaatgattgtcaccccccagagcaatcgacctgtcatgggtattgtgcaagac
acactcacggcagtacgcaaattcactaagagagatgtcttcctggagcggggtgaagtc
atgaacctcttaatgtttctgtccacgtgggatggcaaggtcccacaaccagctatcctc
aagccccggcccctgtggacaggcaagcagatcttctccctcatcatacctggacacatc
aattgtatccgtacccacagcacccatcctgatgatgaagatagtggcccttacaagcac
atctctcctggggacaccaaagttgtagtggagaatggggagcttatcatgggcatcctt
tgtaagaagtccctgggcacctcagcaggctcgctggtccatatctcctacctggagatg
gggcatgacatcacccgcctcttctactccaacattcagactgtcattaacaactggctt
ctcatcgagggtcataccattggcattggggactccattgcagattcaaagacttaccag
gacattcagaacactattaagaaagctaaacaagatgtaatagaggtcattgagaaggct
cataacaatgagctagaacccactccaggaaacacattgcgtcagacatttgagaatcaa
gtgaatcgtattctcaatgatgctcgagacaaaactggctcctctgcacagaaatccctc
tctgaatataacaacttcaagtctatggtggtgtctggagccaagggttccaagatcaac
atctcccaggtcattgctgttgtcgggcagcagaatgtagagggcaagcggatcccattt
ggattcaagcatcggactcttcctcactttatcaaggatgattatggtcctgagagccga
ggctttgtagaaaattcatacttggctggtctcacacccactgagttcttcttccatgcc
atgggaggacgagaaggtctcattgacacggctgttaagactgctgagactgggtatatt
cagcgaaggctgataaagtccatggagtcggtgatggtgaaatatgatgcaactgtgagg
aactccatcaaccaggtggtacagctgcgctatggagaggacggcctggcaggggagagt
gttgagttccagaatctggctacacttaaaccttctaataaagcttttgagaagaagttc
cgttttgattataccaatgagagggccctgcggcgcacccttcaggaggacctggtaaag
gatgtgctgagcaatgcccatatacagaatgagctggaacgggaatttgaacggatgcgt
gaagatcgggaagtgctcagggtcatcttcccaactggtgacagcaaggtggtcctccct
tgtaaccttctgcggatgatctggaatgctcagaaaatcttccacatcaaccctcgcctt
ccctctgacctgcatcccatcaaagtggtagagggagtcaaagaattgagcaagaagttg
gtaattgtgaatggagatgacccactaagtcggcaggcacaggagaatgccacattgctc
ttcaacatccacctaagatccacactctgctctcgccgcatggctgaggagtttcggctg
agtggagaggcctttgactggctgcttggggagatagagtccaagttcaaccaagccatt
gcccatcctggagaaatggtgggagctctggctgctcagtctcttggagaacctgccact
cagatgaccctgaacactttccactatgctggtgtatctgccaagaatgtgacgctgggt
gtgcctcgacttaaggagcttatcaacatttccaagaagccaaagactccttcactcact
gtcttcctgttaggtcaatctgcacgagatgctgaaagagccaaggacattctttgccgc
ttggaacatacaacattgaggaaggtgactgccaatacagccatctactatgaccctaac
ccccagagcacagtggtggcagaagatcaggagtgggtgaatgtgtactatgagatgccc
gactttgacgtggcccggatatctccctggctgctgcgtgtggagctcgaccgaaagcac
atgactgaccggaagcttaccatggaacagattgctgagaaaatcaatgcaggttttggc
gatgatttgaattgtatcttcaacgatgataatgcagagaagctggtccttcgaatccgc
atcatgaacagtgatgaaaacaagatgcaagaggaggaagaggtggtggataaaatggat
gatgatgtcttcctgcgatgcattgagtccaacatgctgacagatatgaccctgcagggt
atcgagcagatcagcaaggtgtacatgcacttacctcagacagacaacaagaagaagatc
atcatcacagaggatggggagttcaaggccctgcaggaatggatcttagagacggatggt
gtgagcctgatgcgggtgctgagtgagaaggatgtagaccctgtgcgcaccacgtccaat
gatattgtggagatcttcacggtactgggcattgaggctgtgcggaaggctctggagcga
gaactgtaccatgtcatctcctttgatggttcttatgtcaattatcggcatttggcgctc
ctgtgtgacactatgacatgccgtggccacttgatggccatcactcgtcatggggtcaac
cgccaggacactggaccgctcatgaaatgctcctttgaggaaacggtggatgtccttatg
gaagcagcagcacatggggagagtgacccgatgaagggagtctctgagaatattatgctg
ggccagctcgctccagctggtactggctgttttgacctcctgcttgatgctgagaagtgc
aaatacggcatggaaatccccaccaatatccctggcctgggggctgctggacctaccggc
atgttctttggctctgcacccagtccgatgggaggaatatctcctgcaatgacaccctgg
aaccagggtgcaactcccgcctatggtgcctggtccccgagtgttgggagcgggatgacc
ccaggagcggccggcttctctcccagtgctgcatctgatgccagtggcttcagcccaggt
tactcccctgcatggtctcccacaccaggctctccgggctcccctggaccctcaagccca
tacatcccctcaccaggtggtgctatgtctcccagctactcaccgacatcaccagcctat
gagccacgctcccctgggggctatacaccccagagcccctcctactcccctacttcacct
tcctactccccaacctctccatcttactctccaaccagtcccaactacagccctacctct
cctagctactcgcccacctcccctagctactcgccaacctctccttcctactcccccacc
tctccaagctattccccaacctctcctagctactccccaacctctccaagctattctcca
acatcacctagctattctccaacttctcccagctactcaccgacatctcctagctactcc
ccaacttctcccagctactcaccaacttcaccaagctattctcccacctcccccagctac
tcaccgacatctcccagctactcaccaacttctccaagctactcaccaacttctccaagc
tactcacccaccagccctaactattctccaactagtcccaactataccccgacatcaccc
agctacagcccaacctcacccagttactcacctacaagtcccaactatacacccaccagc
cctaattacagcccaacctctccaagctattccccaacctcacccagttattcccccacc
tcaccaagctactccccctccagcccacgatatacaccacagtctccaacctacacacca
agctcaccaagctacagtcccagctcaccaagctacagccccacttcacccaagtacacc
ccaactagtccttcctacagtcccagctcaccagagtacaccccagcttctcccaaatac
tcacctacaagccctaaatattcacccacttctcccaagtattctcctaccagccccact
tactcacctaccaccccaaaatattctccaacctccccgacatactcaccaacctctcca
gtctataccccgacctctcccaagtactccccaaccagccctacctactcgcccacttct
cccaagtactcgcccaccagtcccacctactcacccacctctcccaagggctccacctac
tctcccacttctcctggctactcacccactagccccacctacagcctcaccagcccagcc
atcagcccagatgacagcgatgaggagaactga

  All links  
Gene (55)   
   RefGene (50)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (16)   
   RefSeq(nuc) (2)   
   GenBank (7)   
   EMBL (7)   
Protein domain (8)   
   Pfam (8)   
All databases (82)   

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