KEGG   Mus musculus (house mouse): 20112
Entry
20112             CDS       T01002                                 
Symbol
Rps6ka2, 90kDa, D17Wsu134e, Rps6ka-rs1, Rsk3, p90rsk, pp90rsk
Name
(RefSeq) ribosomal protein S6 kinase, polypeptide 2
  KO
K04373  ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04114  Oocyte meiosis
mmu04150  mTOR signaling pathway
mmu04714  Thermogenesis
mmu04720  Long-term potentiation
mmu04722  Neurotrophin signaling pathway
mmu04914  Progesterone-mediated oocyte maturation
mmu04931  Insulin resistance
mmu05135  Yersinia infection
mmu05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    20112 (Rps6ka2)
   04150 mTOR signaling pathway
    20112 (Rps6ka2)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    20112 (Rps6ka2)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    20112 (Rps6ka2)
  09156 Nervous system
   04720 Long-term potentiation
    20112 (Rps6ka2)
   04722 Neurotrophin signaling pathway
    20112 (Rps6ka2)
  09159 Environmental adaptation
   04714 Thermogenesis
    20112 (Rps6ka2)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    20112 (Rps6ka2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    20112 (Rps6ka2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    20112 (Rps6ka2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    20112 (Rps6ka2)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    20112 (Rps6ka2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     20112 (Rps6ka2)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   20112 (Rps6ka2)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     20112 (Rps6ka2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Kdo Pkinase_fungal Pkinase_C Haspin_kinase RIO1 YrbL-PhoP_reg
Other DBs
NCBI-GeneID: 20112
NCBI-ProteinID: NP_035429
MGI: 1342290
Ensembl: ENSMUSG00000023809
UniProt: Q9WUT3 Q7TPD5
Position
17:7356384..7570714
AA seq 733 aa
MELSMKKFTVRRFFSVYLRKKSRSKSSSLSRLEEEGIVKEIDISNHVKEGFEKADPSQFE
LLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPF
IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGI
IYRDLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSFCGTIEYMAPEVVNRRGHTQSA
DWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSLLRALFKRNPCN
RLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDS
PGVPPSANAHHLFRGFSFVASSLVQEPSQQDVPKAPIHPIVQQLHGNNIHFTDGYEIKED
IGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK
YVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNILY
MDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGIL
LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQR
LTAVQVLKHPWIVNREYLSQNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSSLA
QRRGMKRLTSTRL
NT seq 2202 nt   +upstreamnt  +downstreamnt
atggagctgagcatgaagaagttcacggtgcgcaggttcttctccgtgtacctgcgcaag
aagtcgcgctccaagagctccagtctgagtcgcctcgaggaagaaggcattgtgaaggag
attgacattagcaaccatgtgaaggaaggctttgagaaggcagacccctcccagttcgag
ctactaaaggttttaggacaagggtcgtatggaaaggtgttcttggtgaggaaggttaca
ggatcagacgctggtcagctctacgccatgaaggtcctgaagaaagccaccttgaaagtg
cgagaccgggtcagatctaagatggagagagacatcctggcagaggtgaatcaccctttc
attgtcaagctgcattatgcctttcagaccgaaggcaagctctacctgatcctggacttc
ctgcggggaggtgacctcttcaccaggctttccaaagaggtgatgttcacggaggaggat
gtcaagttctacctggctgagctggccttggctctagaccacctccatggcctggggatc
atctacagggatctgaagccagagaatatcctcctggatgaagagggacacattaagatc
acagattttggcttgagcaaggaggccaccgaccatgacaagagagcctattcattctgt
gggactattgaatacatggcgcccgaggtggtgaaccggcgtggacacacacagagtgcc
gactggtggtccttcggtgtgctcatgttcgagatgctcacagggtccctgccattccag
gggaaggacaggaaggaaacaatggccctcatcctcaaagccaagctgggtatgcctcag
ttcctcagtgcggaggctcagagcctgctcagggcccttttcaagcggaacccctgcaac
aggctaggtgctggtgttgatggagtggaggaaattaaacgtcacccgttctttgtcacc
atagactggaataagctgtaccgcaaggagatcaagccacccttcaagccagcagtgggc
aggcctgaggacaccttccactttgaccccgagtttactgcaaggacccccacagattct
cctggtgtccccccaagtgcaaacgcccaccacctcttcagaggattcagctttgtggcc
tccagcctggtccaggagccctcacagcaagacgtgcccaaggcccccattcacccaatt
gtgcagcagctacatgggaacaacatccacttcactgacggctatgagatcaaggaggac
atcggggtgggctcctactcagtgtgcaagcggtgtgtacacaaagccacggatgctgag
tatgctgtgaagatcatcgataagagcaaaagggacccctcggaggagattgagatcctc
ctgcgctatggccagcaccccaacatcatcaccctaaaagatgtctatgatgatggcaag
tacgtctacctggtgatggagctcatgcgaggcggggagctgctggaccgtatcctccgt
cagcggtgcttctcagagcgtgaggccagtgatgtgctctataccatcgccaggaccatg
gactacctgcactcccaaggggttgtccatcgggacctgaaaccaagtaacattctgtac
atggatgagtctggaaaccccgaatctatccgcatctgtgactttgggtttgccaaacag
cttcgagcggagaatgggctgctcatgaccccctgctatactgcaaactttgtagctccc
gaggtcttgaagcggcaaggctacgatgcagcgtgtgatgtctggagcttgggaatcctg
ctgtacaccatgctggctgggttcactccgtttgccaatggcccagacgatacccctgag
gagattctggctaggatcggcagtgggaagtacgccctttctgggggaaactgggactcc
atatctgatgcagcaaaagatgtcgtgtccaagatgctccacgtggaccctcagcaacgc
ctaacagcagttcaagtgttgaagcacccgtggatcgtgaacagagagtacctatcccaa
aaccagctgagcagacaggatgtccatctagtgaagggtgccatggcggccacctacttt
gctctgaacaggaccccacaggcaccgaggctagagcctgtgctctcatctagcttggcc
caacgcagaggcatgaagagactcacgtctaccaggttgtag

  All links  
Gene (11)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (35)   
   RefSeq(nuc) (5)   
   GenBank (15)   
   EMBL (15)   
Protein domain (10)   
   Pfam (10)   
All databases (64)   

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