KEGG   Mus musculus (house mouse): 20698
Entry
20698             CDS       T01002                                 
Symbol
Sphk1, 1110006G24Rik, Sk1, Spk1
Name
(RefSeq) sphingosine kinase 1
  KO
K04718  sphingosine kinase [EC:2.7.1.91]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00600  Sphingolipid metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04071  Sphingolipid signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04148  Efferocytosis
mmu04370  VEGF signaling pathway
mmu04371  Apelin signaling pathway
mmu04666  Fc gamma R-mediated phagocytosis
mmu05152  Tuberculosis
Module
mmu_M00100  Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    20698 (Sphk1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    20698 (Sphk1)
   04071 Sphingolipid signaling pathway
    20698 (Sphk1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    20698 (Sphk1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    20698 (Sphk1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    20698 (Sphk1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphingosine kinase
     20698 (Sphk1)
SSDB
Motif
Pfam: DAGK_cat YegS_C
Other DBs
NCBI-GeneID: 20698
NCBI-ProteinID: NP_001165943
MGI: 1316649
Ensembl: ENSMUSG00000061878
UniProt: Q8CI15
Position
11:116421662..116427502
AA seq 382 aa
MEPVECPRGLLPRPCRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHA
RELVCAEELGHWDALAVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPGGSGNALAASV
NHYAGYEQVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGLRLYSVLSLSWGFVADVDLE
SEKYRRLGEIRFTVGTFFRLASLRIYQGQLAYLPVGTVASKRPASTLVQKGPVDTHLVPL
EEPVPSHWTVVPEQDFVLVLVLLHTHLSSELFAAPMGRCEAGVMHLFYVRAGVSRAALLR
LFLAMQKGKHMELDCPYLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQGQVHPNYLWM
VCGSRDAPSGRDSRRGPPPEEP
NT seq 1149 nt   +upstreamnt  +downstreamnt
atggaaccagtagaatgccctcgaggactgctcccacggccatgcagagtgctggtgctg
ctgaacccccagggtggcaagggcaaggctctgcagctcttccagagccgtgtgcagccc
ttcctggaggaggcagagataacctttaaactgatactcaccgaacggaagaaccatgcc
agggagctggtgtgtgcagaggagttgggtcactgggacgccctggcagtcatgtccggt
gatggtctgatgcatgaggtggtgaatgggctaatggaacggccagactgggagactgcc
atccagaaacccctgtgtagcctccctggaggctccggcaatgcgctggcagcttctgtg
aaccactatgctgggtacgagcaggtgactaatgaagacctgctcatcaactgcacactg
ctgttgtgccgccggcgcctgtcacccatgaacctgctgtccctgcacactgcttctggg
ctgcggctctattctgtgctcagtctgtcctggggctttgttgctgacgtggacctcgag
agtgagaagtacaggcgcttgggggagattcgtttcacagtgggcaccttctttcgccta
gcaagcctgcgcatctaccaaggccaactggcctaccttcctgtaggaactgtggcctct
aagagacccgcctctacactggtgcagaagggccccgtcgacacacaccttgttcctctg
gaggagccagtgccttctcattggactgtggtaccagaacaggacttcgtcctggtgctg
gtgctgctacacacccacctgagctccgagctgtttgcagcacccatgggccgctgtgag
gctggtgttatgcatctgttctacgtacgtgcgggggtgtcaagggctgcgctgctgcgc
ctcttcctggccatgcagaagggcaagcatatggaacttgactgtccatacctggttcat
gtgcccgtggttgctttccgcctggagcccaggagccagaggggcgtgttttctgtggat
ggagagctgatggtatgtgaagctgtgcagggccaagtgcacccaaactacctttggatg
gtctgtggcagcagagatgccccatccggccgggactcccggcgggggccacctccagaa
gaaccataa

  All links  
Gene (9)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (38)   
   RefSeq(nuc) (14)   
   GenBank (12)   
   EMBL (12)   
Protein domain (2)   
   Pfam (2)   
All databases (64)   

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