KEGG   Mus musculus (mouse): 20698
Entry
20698             CDS       T01002                                 

Gene name
Sphk1, 1110006G24Rik, SK, Sk1, Spk1
Definition
(RefSeq) sphingosine kinase 1
  KO
K04718  sphingosine kinase [EC:2.7.1.91]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00600  Sphingolipid metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04071  Sphingolipid signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04370  VEGF signaling pathway
mmu04371  Apelin signaling pathway
mmu04666  Fc gamma R-mediated phagocytosis
mmu05152  Tuberculosis
Module
mmu_M00100  Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    20698 (Sphk1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    20698 (Sphk1)
   04371 Apelin signaling pathway
    20698 (Sphk1)
   04020 Calcium signaling pathway
    20698 (Sphk1)
   04072 Phospholipase D signaling pathway
    20698 (Sphk1)
   04071 Sphingolipid signaling pathway
    20698 (Sphk1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    20698 (Sphk1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    20698 (Sphk1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphingosine kinase
     20698 (Sphk1)
SSDB
Motif
Pfam: DAGK_cat YegS_C
Other DBs
NCBI-GeneID: 20698
NCBI-ProteinID: NP_001165943
MGI: 1316649
Ensembl: ENSMUSG00000061878
Vega: OTTMUSG00000003900
UniProt: Q8CI15
Position
11; 11 E2
AA seq 382 aa
MEPVECPRGLLPRPCRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHA
RELVCAEELGHWDALAVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPGGSGNALAASV
NHYAGYEQVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGLRLYSVLSLSWGFVADVDLE
SEKYRRLGEIRFTVGTFFRLASLRIYQGQLAYLPVGTVASKRPASTLVQKGPVDTHLVPL
EEPVPSHWTVVPEQDFVLVLVLLHTHLSSELFAAPMGRCEAGVMHLFYVRAGVSRAALLR
LFLAMQKGKHMELDCPYLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQGQVHPNYLWM
VCGSRDAPSGRDSRRGPPPEEP
NT seq 1149 nt   +upstreamnt  +downstreamnt
atggaaccagtagaatgccctcgaggactgctcccacggccatgcagagtgctggtgctg
ctgaacccccagggtggcaagggcaaggctctgcagctcttccagagccgtgtgcagccc
ttcctggaggaggcagagataacctttaaactgatactcaccgaacggaagaaccatgcc
agggagctggtgtgtgcagaggagttgggtcactgggacgccctggcagtcatgtccggt
gatggtctgatgcatgaggtggtgaatgggctaatggaacggccagactgggagactgcc
atccagaaacccctgtgtagcctccctggaggctccggcaatgcgctggcagcttctgtg
aaccactatgctgggtacgagcaggtgactaatgaagacctgctcatcaactgcacactg
ctgttgtgccgccggcgcctgtcacccatgaacctgctgtccctgcacactgcttctggg
ctgcggctctattctgtgctcagtctgtcctggggctttgttgctgacgtggacctcgag
agtgagaagtacaggcgcttgggggagattcgtttcacagtgggcaccttctttcgccta
gcaagcctgcgcatctaccaaggccaactggcctaccttcctgtaggaactgtggcctct
aagagacccgcctctacactggtgcagaagggccccgtcgacacacaccttgttcctctg
gaggagccagtgccttctcattggactgtggtaccagaacaggacttcgtcctggtgctg
gtgctgctacacacccacctgagctccgagctgtttgcagcacccatgggccgctgtgag
gctggtgttatgcatctgttctacgtacgtgcgggggtgtcaagggctgcgctgctgcgc
ctcttcctggccatgcagaagggcaagcatatggaacttgactgtccatacctggttcat
gtgcccgtggttgctttccgcctggagcccaggagccagaggggcgtgttttctgtggat
ggagagctgatggtatgtgaagctgtgcagggccaagtgcacccaaactacctttggatg
gtctgtggcagcagagatgccccatccggccgggactcccggcgggggccacctccagaa
gaaccataa

KEGG   Mus musculus (mouse): 56632
Entry
56632             CDS       T01002                                 

Gene name
Sphk2, C76851, Sk2, Spk2
Definition
(RefSeq) sphingosine kinase 2
  KO
K04718  sphingosine kinase [EC:2.7.1.91]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00600  Sphingolipid metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04071  Sphingolipid signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04370  VEGF signaling pathway
mmu04371  Apelin signaling pathway
mmu04666  Fc gamma R-mediated phagocytosis
mmu05152  Tuberculosis
Module
mmu_M00100  Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    56632 (Sphk2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    56632 (Sphk2)
   04371 Apelin signaling pathway
    56632 (Sphk2)
   04020 Calcium signaling pathway
    56632 (Sphk2)
   04072 Phospholipase D signaling pathway
    56632 (Sphk2)
   04071 Sphingolipid signaling pathway
    56632 (Sphk2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    56632 (Sphk2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    56632 (Sphk2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphingosine kinase
     56632 (Sphk2)
SSDB
Motif
Pfam: DAGK_cat YegS_C
Other DBs
NCBI-GeneID: 56632
NCBI-ProteinID: NP_001166032
MGI: 1861380
Ensembl: ENSMUSG00000057342
Vega: OTTMUSG00000023186
UniProt: Q9JIA7 Q58E38
Position
7; 7 B3
AA seq 617 aa
MAPPPLLPVAASTPILHGEFGSYPANGPRFALTLTTQALHIQRLRPKPEARPRDGLVSLD
EVSGCGTLQSRSPEDTAAYFCIYTYPRGRRGGRRRATRTFRADGATTYEENRAEAQRWAT
ALTCLLRGVPLSGDQEITPELLPRKPRLLILVNPFGGRGLAWQRCMDHVVPMISEAGLSF
NLIQTERQNHARELVQGLSLSEWEGIVTVSGDGLLYEVLNGLLDRPDWEDAVRMPIGVLP
CGSGNALAGAVNHHGGFEQVVGVDLLLNCSLLLCRGGSHPLDLLSVTLASGSRCFSFLSV
AWGFLSDVDIHSERFRALGSARFTLGAVLGLASLHTYRGRLSYLPATTEPALPIPGHSLP
RAKSELVLAPAPAPAATHSPLHRSVSDLPLPLPQPALVSPGSPEPLPDLSLNGGGPELTG
DWGGAGDAPLSPDPLLPSSPNALKTAQLSPIAEGPPEMPASSGFLPPTHSAPEASTWGPV
DHLLPPLGSPLPQDWVTIEGEFVLMLGILPSHLCADLMAAPHARFDDGVVHLCWVRSGIS
RAALLRILLAMEHGNHFSLGCPHLGYAAARAFRLEPLTPRGLLTVDGELVEYGPIQAQVH
PGLATLLTGPAGQKPQA
NT seq 1854 nt   +upstreamnt  +downstreamnt
atggccccaccaccactactgccagtggctgccagcactccaatcctgcacggcgagttt
ggttcctacccggccaacggcccacggtttgccctcaccctcacaacacaagccctacac
atacagcgactacgcccaaagccagaagcccggccccgagatggtctagtctctctggat
gaggtctcgggctgtggcaccctgcagagccgtagccccgaggacactgcagcctacttc
tgcatctacacctacccacgtggccgtcgagggggccggcgcagagctacgcggaccttc
cgggcggatggggccaccacttatgaggagaatcgtgcagaggcccagcgctgggccact
gccctcacgtgtctcctccgaggagtgcctctgtcaggggaccaggaaatcacccctgaa
ttgctgccccggaagcccaggctgctcatattggtcaatccctttggggggcggggcctg
gcctggcagcgctgtatggaccacgtggtgccaatgatctctgaagctgggctgtccttc
aacctcatacagacagaacgacagaaccatgcccgtgagctggtgcaggggttaagcctg
agtgagtgggaaggcattgtcactgtgtctggagacgggctgctttacgaggtgctgaat
gggctccttgatcggccagactgggaggatgccgtgcggatgcccattggtgtcctcccc
tgtggatcgggcaatgcgctagctggggcggtgaaccatcatggcgggtttgagcaggtt
gtcggtgttgacctgttgctcaactgctcgcttcttctctgccgtggtggcagccatcct
ctggacctgctctctgtgacgctagcctcgggatcccgctgtttttccttcctgtcagtg
gcctggggattcttgtcagatgtggacattcacagtgagcgcttcagggccctgggcagc
gctcgattcacactgggtgcagtgctaggcctggcctcgttgcatacctaccgtggacgc
ctctcctacctccccgctaccacagaaccagccttgcccatcccaggccacagtctgcct
cgagccaagtcagaactagtcttggctccagccccagcccccgccgccacccactcgcct
ctacatcgatctgtgtctgacctgcccctgccccttccccagcctgccttggtctcccct
ggctcccctgagcccctgcctgacctgtccctcaatggtggtggtccagagctgactgga
gactggggaggagctggggatgcacctctgtccccagacccactgctgccttcatccccc
aacgctctcaaaacagctcagctttcacccatcgctgaagggcccccagaaatgccagca
tcttcggggttcctgcctcccacccacagtgccccagaagcctctacctggggcccagtg
gaccacctcctccctcccctgggctctccactgccccaagactgggtgacaatagagggg
gagtttgtactcatgttgggcatcttgccgagccacctctgcgcagacctgatggcagcc
ccacatgcacgctttgatgatggcgttgtgcacctgtgttgggtgcggagcggcatctca
cgggctgcacttctacgcattttgctggccatggagcatggaaaccacttcagcctgggc
tgcccccatctgggctatgctgcagcacgtgccttccgccttgaaccactcacgcctcgt
ggcctgctcactgtagatggggagttagtggagtatgggccaatacaggcgcaggtgcac
ccaggtctcgccacgctgctcactgggcctgcaggtcaaaagccacaagcctga

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