KEGG   Mus musculus (mouse): 20846
Entry
20846             CDS       T01002                                 

Gene name
Stat1, 2010005J02Rik, AA408197
Definition
(RefSeq) signal transducer and activator of transcription 1
  KO
K11220  signal transducer and activator of transcription 1
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04062  Chemokine signaling pathway
mmu04217  Necroptosis
mmu04380  Osteoclast differentiation
mmu04620  Toll-like receptor signaling pathway
mmu04621  NOD-like receptor signaling pathway
mmu04625  C-type lectin receptor signaling pathway
mmu04630  JAK-STAT signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04917  Prolactin signaling pathway
mmu04919  Thyroid hormone signaling pathway
mmu04933  AGE-RAGE signaling pathway in diabetic complications
mmu04935  Growth hormone synthesis, secretion and action
mmu05140  Leishmaniasis
mmu05145  Toxoplasmosis
mmu05152  Tuberculosis
mmu05160  Hepatitis C
mmu05161  Hepatitis B
mmu05162  Measles
mmu05164  Influenza A
mmu05165  Human papillomavirus infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05171  Coronavirus disease - COVID-19
mmu05200  Pathways in cancer
mmu05212  Pancreatic cancer
mmu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmu05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    20846 (Stat1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    20846 (Stat1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    20846 (Stat1)
   04621 NOD-like receptor signaling pathway
    20846 (Stat1)
   04625 C-type lectin receptor signaling pathway
    20846 (Stat1)
   04658 Th1 and Th2 cell differentiation
    20846 (Stat1)
   04659 Th17 cell differentiation
    20846 (Stat1)
   04062 Chemokine signaling pathway
    20846 (Stat1)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    20846 (Stat1)
   04935 Growth hormone synthesis, secretion and action
    20846 (Stat1)
   04919 Thyroid hormone signaling pathway
    20846 (Stat1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    20846 (Stat1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20846 (Stat1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    20846 (Stat1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    20846 (Stat1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    20846 (Stat1)
   05160 Hepatitis C
    20846 (Stat1)
   05171 Coronavirus disease - COVID-19
    20846 (Stat1)
   05164 Influenza A
    20846 (Stat1)
   05162 Measles
    20846 (Stat1)
   05168 Herpes simplex virus 1 infection
    20846 (Stat1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    20846 (Stat1)
   05169 Epstein-Barr virus infection
    20846 (Stat1)
   05165 Human papillomavirus infection
    20846 (Stat1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    20846 (Stat1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    20846 (Stat1)
   05140 Leishmaniasis
    20846 (Stat1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    20846 (Stat1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    20846 (Stat1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20846 (Stat1)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    20846 (Stat1)
SSDB
Motif
Pfam: STAT_alpha STAT_int STAT_bind STAT1_TAZ2bind SH2 BLI1 BORCS7 NPV_P10
Other DBs
NCBI-GeneID: 20846
NCBI-ProteinID: NP_001192242
MGI: 103063
Ensembl: ENSMUSG00000026104
Vega: OTTMUSG00000046734
UniProt: Q8CFQ1 Q8C8M3 A0A087WSP5
Position
1 C1.1; 1 26.81 cM
AA seq 755 aa
MSQWFELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAAYDVSFATIRFHDL
LSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPVQMSMIIYNCLKEERKILENAQ
RFNQAQEGNIQNTVMLDKQKELDSKVRNVKDQVMCIEQEIKTLEELQDEYDFKCKTSQNR
EGEANGVAKSDQKQEQLLLHKMFLMLDNKRKEIIHKIRELLNSIELTQNTLINDELVEWK
RRQQSACIGGPPNACLDQLQSWFTIVAETLQQIRQQLKKLEELEQKFTYEPDPITKNKQV
LSDRTFLLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKV
KVSFDKDVNEKNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGNRTN
EGPLIVTEELHSLSFETQLCQPGLVIDLEVFVPFQTTSLPVVVISNVSQLPSGWASILWY
NMLVTEPRNLSFFLNPPCAWWSQLSEVLSWQFSSVTKRGLNADQLSMLGEKLLGPNAGPD
GLIPWTRFCKENINDKNFSFWPWIDTILELIKKHLLCLWNDGCIMGFISKERERALLKDQ
QPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVM
AAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDDPKRTGYIKTELISVSEVHP
SRLQTTDNLLPMSPEEFDEMSRIVGPEFDSMMSTV
NT seq 2268 nt   +upstreamnt  +downstreamnt
atgtcacagtggttcgagcttcagcagctggactccaagttcctggagcaggtccaccag
ctgtacgatgacagtttccccatggaaatcagacagtacctggcccagtggctggaaaag
caagactgggagcacgctgcctatgatgtctcgtttgcgaccatccgcttccatgacctc
ctctcacagctggacgaccagtacagccgcttttctctggagaataatttcttgttgcag
cacaacatacggaaaagcaagcgtaatctccaggataacttccaagaagatcccgtacag
atgtccatgatcatctacaactgtctgaaggaagaaaggaagattttggaaaatgcccaa
agatttaatcaggcccaggagggaaatattcagaacactgtgatgttagataaacagaag
gagctggacagtaaagtcagaaatgtgaaggatcaagtcatgtgcatagagcaggaaatc
aagaccctagaagaattacaagatgaatatgactttaaatgcaaaacctctcagaacaga
gaaggtgaagccaatggtgtggcgaagagcgaccaaaaacaggaacagctgctgctccac
aagatgtttttaatgcttgacaataagagaaaggagataattcacaaaatcagagagttg
ctgaattccatcgagctcactcagaacactctgattaatgacgagctcgtggagtggaag
cgaaggcagcagagcgcctgcatcgggggaccgcccaacgcctgcctggatcagctgcaa
agctggttcaccattgttgcagagaccctgcagcagatccgtcagcagcttaaaaagctg
gaggagttggaacagaaattcacctatgagcccgaccctattacaaaaaacaagcaggtg
ttgtcagatcgaaccttcctcctcttccagcagctcattcagagctccttcgtggtagaa
cgacagccgtgcatgcccactcacccgcagaggcccctggtcttgaagactggggtacag
ttcactgtcaagctgagactgttggtgaaattgcaagagctgaactataacttgaaagtg
aaagtctcatttgacaaagatgtgaacgagaaaaacacagttaaaggatttcggaagttc
aacatcttgggtacgcacacaaaagtgatgaacatggaagaatccaccaacggaagtctg
gcagctgagttccgacacctgcaactgaaggaacagaaaaacgctgggaacagaactaat
gaggggcctctcattgtcaccgaagaacttcactctcttagctttgaaacccagttgtgc
cagccaggcttggtgattgacctggaggtctttgttccctttcagaccacctctcttcct
gtcgtggtgatctccaacgtcagccagctccccagtggctgggcgtctatcctgtggtac
aacatgctggtgacagagcccaggaatctctccttcttcctgaaccccccgtgcgcgtgg
tggtcccagctctcagaggtgttgagttggcagttttcatcagtcaccaagagaggtctg
aacgcagaccagctgagcatgctgggagagaagctgctgggccctaatgctggccctgat
ggtcttattccatggacaaggttttgtaaggaaaatattaatgataaaaatttctccttc
tggccttggattgacaccatcctagagctcattaagaagcacctgctgtgcctctggaat
gatgggtgcattatgggcttcatcagcaaggagcgagaacgcgctctgctcaaggaccag
cagccagggacgttcctgcttagattcagtgagagctcccgggaaggggccatcacattc
acatgggtggaacggtcccagaacggaggtgaacctgacttccatgccgtggagccctac
acgaaaaaagaactttcagctgttactttcccagatattattcgcaactacaaagtcatg
gctgccgagaacataccagagaatcccctgaagtatctgtaccccaatattgacaaagac
cacgcctttgggaagtattattccagaccaaaggaagcaccagaaccgatggagcttgac
gaccctaagcgaactggatacatcaagactgagttgatttctgtgtctgaagtccaccct
tctagacttcagaccacagacaacctgcttcccatgtctccagaggagtttgatgagatg
tcccggatagtgggccccgaatttgacagtatgatgagcacagtataa

KEGG   Mus musculus (mouse): 20847
Entry
20847             CDS       T01002                                 

Gene name
Stat2, 1600010G07Rik, AW496480
Definition
(RefSeq) signal transducer and activator of transcription 2
  KO
K11221  signal transducer and activator of transcription 2
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04062  Chemokine signaling pathway
mmu04217  Necroptosis
mmu04380  Osteoclast differentiation
mmu04621  NOD-like receptor signaling pathway
mmu04625  C-type lectin receptor signaling pathway
mmu04630  JAK-STAT signaling pathway
mmu05160  Hepatitis C
mmu05161  Hepatitis B
mmu05162  Measles
mmu05164  Influenza A
mmu05165  Human papillomavirus infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05171  Coronavirus disease - COVID-19
mmu05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    20847 (Stat2)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    20847 (Stat2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    20847 (Stat2)
   04625 C-type lectin receptor signaling pathway
    20847 (Stat2)
   04062 Chemokine signaling pathway
    20847 (Stat2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    20847 (Stat2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20847 (Stat2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    20847 (Stat2)
   05160 Hepatitis C
    20847 (Stat2)
   05171 Coronavirus disease - COVID-19
    20847 (Stat2)
   05164 Influenza A
    20847 (Stat2)
   05162 Measles
    20847 (Stat2)
   05168 Herpes simplex virus 1 infection
    20847 (Stat2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    20847 (Stat2)
   05169 Epstein-Barr virus infection
    20847 (Stat2)
   05165 Human papillomavirus infection
    20847 (Stat2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20847 (Stat2)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    20847 (Stat2)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int STAT2_C SH2 IRF-2BP1_2
Other DBs
NCBI-GeneID: 20847
NCBI-ProteinID: NP_064347
MGI: 103039
Ensembl: ENSMUSG00000040033
UniProt: Q9QXJ2
Structure
PDB: 
5OEN

Position
10 D3; 10 76.5 cM
AA seq 922 aa
MAQWEMLQNLDSLFLDQLHQVYSQSILPMDVRQHLATWIEDQNWREAALGSDDAKANMLY
FSILDQLNQWDHYSSDSNHFLLQHNLRKFSRDIQTFPNGPTQLAEMIFNLLLEEQRILNQ
AQRAQEVQPPPAPEAVVESQQLEIENRIQGLHVDIEFLVRSIRQLKDEQDVFSFRYTVFS
LKKTSSSDPHQSQQAQLVQATANKVDRMRKEVLDISKGLVGRLTTLVDLLLPKLDEWKVQ
QQKSCIGAPPPELQLEQLEQWLTAGAKFLFHLRQLLKQLKEMSHMLRYKGDMFGQGVDLQ
NAQVMELLQRLLQRSFVVETQPCMPQTLHRPLILKTGNKFTVRTRLLVRLQEGSESLKAE
VSVDRNSDLPGFRKFNILTSNQKTLTPEEGQRQGLIWDFGFLTLVEQRAVGAGKGNKGPL
AVTEELHVISFVVEYVYQGLKMKLQTDTLPVVIISNMNQLSIAWASILWFNMLSPNPKNQ
QFFCQAPKAPWSLLGPVLSWQFSSYVGRGLDSEQLGMLRTKLFGKSCKMEDALLSWVDFC
KRESPPGKIPFWTWLDKILELVHDHLKDLWKDGRIMGFVSRNQERRLLKKMLSGTFLLRF
SETSEGGITCSWVEHQDDDKVEIYSVQPYTKEVLQSLPLTEIIRHYQVLAEENIPENPLR
FLYPRIPRDEAFGCYYQEKVNFEEQRKYLKHKLIVISNRQVDELQQPLELKQDSESLEVN
AELLLAHDQELPLMMQTGLVLGTELKVDPILSTAPQVLLEPAPQVLLEPAPQVPLEPAPQ
VLLEPAPQVLLEPAPQVLLEPAPQVLLEPAPQVQLEPAPQVLLELAPQVLLEPAPQVLLE
LAPQVQLEPAHLLQQPSESDLPEDLQQISVEDLKKLSNPSTEYITTNENPMLAGESSGDE
TSIPYHSHFDADGLLGWTLDTF
NT seq 2769 nt   +upstreamnt  +downstreamnt
atggcgcagtgggagatgttgcagaaccttgacagcctgttcctggaccagttacaccag
gtctactcacagagcatcctgccaatggacgttcgacagcatttggctacctggattgaa
gaccagaactggagggaagctgcgctgggcagtgatgacgccaaggccaacatgctatac
ttcagcatcctggaccaactgaaccagtgggaccactacagctcagactccaatcacttt
ttattacagcataacttgcgaaaattcagccgggatattcagacctttcccaatggccct
acccagttggctgagatgatctttaatcttcttctggaagagcaaaggattctgaatcag
gctcaaagagctcaagaggtgcagcccccaccagcccccgaagcagttgtggagagccag
cagcttgagattgaaaatcgaatccagggtttacatgtggacattgagttcttggtgaga
tccatcaggcagctgaaggacgaacaggatgtcttcagcttcagatacacagttttcagt
ctgaagaagacgtcgtcttcagacccccatcagagccaacaggcgcagcttgtgcaggca
acagccaacaaagtcgacagaatgagaaaggaggtgctggacatctccaaaggactggtt
ggccgattaaccaccctggtcgacctattgctgcccaagctggacgagtggaaggtgcag
cagcagaagtcctgcattggagccccgccccccgagctgcagctggaacagctggaacag
tggttgacggctggagcaaagttcttgttccaccttcggcagctactgaagcagctgaag
gagatgagtcacatgcttcggtataagggtgacatgtttggccaaggggtggacctgcag
aatgcccaagtcatggagttacttcagcgtctgctccaaaggtcctttgtagtagaaacc
cagccctgcatgccccagactctccaccgacccctcatcctgaagactgggaacaagttc
accgtccgaacaagacttctggtgagactccaggaaggcagcgaatcactcaaagcagaa
gtctctgtcgacaggaattcagacttaccaggcttccggaagttcaacattctgacctca
aaccaaaaaaccttgaccccggaggagggccagagacagggcttaatttgggacttcggc
ttcttgactctggtggagcaacgcgctgtgggtgcaggaaagggcaacaaggggccgctg
gcagtgacagaggagttacatgtcatcagcttcgtggttgagtacgtgtaccagggtctg
aagatgaagctgcagacggacactctccctgttgtgattatttctaacatgaaccaactc
tccattgcctgggcctccattctctggttcaacatgctcagcccaaatcccaagaaccag
cagttcttctgccaagctccgaaagccccctggagtttgctgggacctgtgctcagctgg
cagttctcctcttacgttggccgaggcctcgattctgagcagctgggcatgctgagaacc
aagctgtttggaaagagctgcaagatggaggatgcgctgttgtcctgggtagacttttgc
aagcgagagagcccccctggtaagatccctttctggacctggctggacaaaattctggag
ctggtgcacgaccacctgaaggatctctggaaggatgggcgcatcatgggctttgtgagc
cgcaaccaggaacgcagactgctgaagaagatgttgtctggcaccttcctactgcgcttc
agtgaaacttctgaagggggcattacttgttcttgggtggagcaccaggatgacgataaa
gtcgaaatctactcagtgcagccctacaccaaggaagtgttacagtcactcccactgaca
gagatcatccgccactaccaggttcttgccgaagagaacatccccgagaacccactccgc
ttcctctatccccgaatccctcgggacgaagcttttgggtgttactaccaggaaaaagtt
aattttgaagaacagaggaaatatttgaaacataaactcattgtgatctctaacagacag
gtggacgagctgcagcagcctctggagctcaaacaggattcagagtccttagaagtgaat
gcagagctcttgttagcacacgaccaggagttgccattgatgatgcagactgggctggtt
ctgggcacagagctgaaagtggaccccatactgagtacagccccacaagtcctgctggag
ccagccccacaagtcctgctggagccagccccacaagtcccgctggagccagccccacaa
gtcctgctggagccagccccacaagtcctgctggagccagccccacaagtcctgctggag
ccagccccacaagtcctgctggagccagccccacaagtccagctggagccagccccacaa
gtcctgctggagctagccccacaagtcctgctggagccagccccacaagtcctgctggag
ctagccccacaagtccagctggagccagcacacttgctgcagcagccatcagagtcagat
ttgcctgaggacctgcagcagattagcgtggaggatctgaaaaaattaagcaacccgagt
actgaatacatcacaaccaacgaaaacccaatgttggctggcgagagcagtggagatgag
acttccataccctaccacagccattttgatgcggatggactcttgggatggactcttgat
accttctga

KEGG   Mus musculus (mouse): 20848
Entry
20848             CDS       T01002                                 

Gene name
Stat3, 1110034C02Rik, A, AW109958, Aprf
Definition
(RefSeq) signal transducer and activator of transcription 3
  KO
K04692  signal transducer and activator of transcription 3
Organism
mmu  Mus musculus (mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu04062  Chemokine signaling pathway
mmu04066  HIF-1 signaling pathway
mmu04068  FoxO signaling pathway
mmu04217  Necroptosis
mmu04550  Signaling pathways regulating pluripotency of stem cells
mmu04630  JAK-STAT signaling pathway
mmu04659  Th17 cell differentiation
mmu04917  Prolactin signaling pathway
mmu04920  Adipocytokine signaling pathway
mmu04931  Insulin resistance
mmu04933  AGE-RAGE signaling pathway in diabetic complications
mmu04935  Growth hormone synthesis, secretion and action
mmu05145  Toxoplasmosis
mmu05160  Hepatitis C
mmu05161  Hepatitis B
mmu05162  Measles
mmu05163  Human cytomegalovirus infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05169  Epstein-Barr virus infection
mmu05171  Coronavirus disease - COVID-19
mmu05200  Pathways in cancer
mmu05203  Viral carcinogenesis
mmu05205  Proteoglycans in cancer
mmu05206  MicroRNAs in cancer
mmu05212  Pancreatic cancer
mmu05221  Acute myeloid leukemia
mmu05223  Non-small cell lung cancer
mmu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmu05321  Inflammatory bowel disease
mmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    20848 (Stat3)
   04066 HIF-1 signaling pathway
    20848 (Stat3)
   04068 FoxO signaling pathway
    20848 (Stat3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    20848 (Stat3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    20848 (Stat3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    20848 (Stat3)
   04062 Chemokine signaling pathway
    20848 (Stat3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    20848 (Stat3)
   04917 Prolactin signaling pathway
    20848 (Stat3)
   04935 Growth hormone synthesis, secretion and action
    20848 (Stat3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20848 (Stat3)
   05206 MicroRNAs in cancer
    20848 (Stat3)
   05205 Proteoglycans in cancer
    20848 (Stat3)
   05203 Viral carcinogenesis
    20848 (Stat3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    20848 (Stat3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    20848 (Stat3)
   05221 Acute myeloid leukemia
    20848 (Stat3)
   05223 Non-small cell lung cancer
    20848 (Stat3)
  09172 Infectious disease: viral
   05161 Hepatitis B
    20848 (Stat3)
   05160 Hepatitis C
    20848 (Stat3)
   05171 Coronavirus disease - COVID-19
    20848 (Stat3)
   05162 Measles
    20848 (Stat3)
   05163 Human cytomegalovirus infection
    20848 (Stat3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    20848 (Stat3)
   05169 Epstein-Barr virus infection
    20848 (Stat3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    20848 (Stat3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    20848 (Stat3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    20848 (Stat3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    20848 (Stat3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    20848 (Stat3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    20848 (Stat3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20848 (Stat3)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    20848 (Stat3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 Syntaxin-6_N DUF4795 Fib_alpha
Other DBs
NCBI-GeneID: 20848
NCBI-ProteinID: NP_998824
MGI: 103038
Ensembl: ENSMUSG00000004040
Vega: OTTMUSG00000002128
UniProt: P42227 Q3ULI4
Structure
PDB: 
1BG1 4E68 4ZIA 3CWG

Position
11 D; 11 63.82 cM
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggctcagtggaaccagctgcagcagctggacacacgctacctggagcagctgcaccag
ctgtacagcgacagcttccccatggagctgcggcagttcctggcaccttggattgagagt
caagactgggcatatgcagccagcaaagagtcacatgccacgttggtgtttcataatctc
ttgggtgaaattgaccagcaatatagccgattcctgcaagagtccaatgtcctctatcag
cacaaccttcgaagaatcaagcagtttctgcagagcaggtatcttgagaagccaatggaa
attgcccggatcgtggcccgatgcctgtgggaagagtctcgcctcctccagacggcagcc
acggcagcccagcaagggggccaggccaaccacccaacagccgccgtagtgacagagaag
cagcagatgttggagcagcatcttcaggatgtccggaagcgagtgcaggatctagaacag
aaaatgaaggtggtggagaacctccaggacgactttgatttcaactacaaaaccctcaag
agccaaggagacatgcaggatctgaatggaaacaaccagtctgtgaccagacagaagatg
cagcagctggaacagatgctcacagccctggaccagatgcggagaagcattgtgagtgag
ctggcggggctcttgtcagcaatggagtacgtgcagaagacactgactgatgaagagctg
gctgactggaagaggcggcagcagatcgcgtgcatcggaggccctcccaacatctgcctg
gaccgtctggaaaactggataacttcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagctgcagcagaaagtgtcctacaagggcgaccctatcgtgcag
caccggcccatgctggaggagaggatcgtggagctgttcagaaacttaatgaagagtgcc
ttcgtggtggagcggcagccctgcatgcccatgcacccggaccggcccttagtcatcaag
actggtgtccagtttaccacgaaagtcaggttgctggtcaaatttcctgagttgaattat
cagcttaaaattaaagtgtgcattgataaagactctggggatgttgctgccctcagaggg
tctcggaaatttaacattctgggcacgaacacaaaagtgatgaacatggaggagtctaac
aacggcagcctgtctgcagagttcaagcacctgacccttagggagcagagatgtgggaat
ggaggccgtgccaattgtgatgcctccttgatcgtgactgaggagctgcacctgatcacc
ttcgagactgaggtgtaccaccaaggcctcaagattgacctagagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcttgggcatcaatcctgtggtat
aacatgctgaccaataaccccaagaacgtgaacttcttcactaagccgccaattggaacc
tgggaccaagtggccgaggtgctcagctggcagttctcgtccaccaccaagcgggggctg
agcatcgagcagctgacaacgctggctgagaagctcctagggcctggtgtgaactactca
gggtgtcagatcacatgggctaaattctgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctagacaatatcatcgaccttgtgaaaaagtatatcttggccctttgg
aatgaagggtacatcatgggtttcatcagcaaggagcgggagcgggccatcctaagcaca
aagcccccgggcaccttcctactgcgcttcagcgagagcagcaaagaaggaggggtcact
ttcacttgggtggaaaaggacatcagtggcaagacccagatccagtctgtagagccatac
accaagcagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gatgcgaccaacatcctggtgtctccacttgtctacctctaccccgacattcccaaggag
gaggcatttggaaagtactgtaggcccgagagccaggagcaccccgaagccgacccaggt
agtgctgccccgtacctgaagaccaagttcatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataac
ggtgaaggtgctgagccctcagcaggagggcagtttgagtcgctcacgtttgacatggat
ctgacctcggagtgtgctacctcccccatgtga

KEGG   Mus musculus (mouse): 20849
Entry
20849             CDS       T01002                                 

Gene name
Stat4
Definition
(RefSeq) signal transducer and activator of transcription 4
  KO
K11222  signal transducer and activator of transcription 4
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04217  Necroptosis
mmu04630  JAK-STAT signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu05161  Hepatitis B
mmu05200  Pathways in cancer
mmu05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    20849 (Stat4)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    20849 (Stat4)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    20849 (Stat4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20849 (Stat4)
  09172 Infectious disease: viral
   05161 Hepatitis B
    20849 (Stat4)
  09163 Immune disease
   05321 Inflammatory bowel disease
    20849 (Stat4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20849 (Stat4)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    20849 (Stat4)
SSDB
Motif
Pfam: STAT_alpha STAT_int STAT_bind SH2 NPV_P10 Prp19
Other DBs
NCBI-GeneID: 20849
NCBI-ProteinID: NP_001295195
MGI: 103062
Ensembl: ENSMUSG00000062939
Vega: OTTMUSG00000046732
UniProt: P42228 Q3V157
Structure
PDB: 
1BGF

Position
1 C1.1; 1 26.67 cM
AA seq 748 aa
MSQWNQVQQLEIKFLEQVDQFYDDNFPMEIRHLLAQWIETQDWEVASNNETMATILLQNL
LIQLDEQLGRVSKEKNLLLIHNLKRIRKVLQGKFHGNPMHVAVVISNCLREERRILAAAN
MPIQGPLEKSLQSSSVSERQRNVEHKVSAIKNSVQMTEQDTKYLEDLQDEFDYRYKTIQT
MDQGDKNSILVNQEVLTLQEMLNSLDFKRKEALSKMTQIVNETDLLMNSMLLEELQDWKK
RQQIACIGGPLHNGLDQLQNCFTLLAESLFQLRQQLEKLQEQSTKMTYEGDPIPAQRAHL
LERATFLIYNLFKNSFVVERQPCMPTHPQRPMVLKTLIQFTVKLRLLIKLPELNYQVKVK
ASIDKNVSTLSNRRFVLCGTHVKAMSSEESSNGSLSVEFRHLQPKEMKCSTGSKGNEGCH
MVTEELHSITFETQICLYGLTINLETSSLPVVMISNVSQLPNAWASIIWYNVSTNDSQNL
VFFNNPPSVTLGQLLEVMSWQFSSYVGRGLNSEQLNMLAEKLTVQSNYNDGHLTWAKFCK
EHLPGKTFTFWTWLEAILDLIKKHILPLWIDGYIMGFVSKEKERLLLKDKMPGTFLLRFS
ESHLGGITFTWVDQSENGEVRFHSVEPYNKGRLSALPFADILRDYKVIMAENIPENPLKY
LYPDIPKDKAFGKHYSSQPCEVSRPTERGDKGYVPSVFIPISTIRSDSTEPQSPSDLLPM
SPSAYAVLRENLSPTTIETAMNSPYSAE
NT seq 2247 nt   +upstreamnt  +downstreamnt
atgtctcagtggaatcaagtccaacaattagaaatcaagtttttggagcaagtagatcag
ttctatgatgacaactttcctatggaaatccggcatctgctagctcagtggattgagact
caagactgggaagtagcttctaacaatgaaactatggcaacaattctgcttcaaaactta
ctaatacaattggatgaacagttggggcgtgtttccaaagaaaaaaatctgctattgatt
cacaatctaaagagaattagaaaagttcttcagggcaagtttcatggaaatccaatgcat
gtagctgtggtaatttcaaattgcttaagggaagagaggagaatattggctgcagccaac
atgcctatccagggacctctggagaaatccttacagagttcttcagtttctgaaagacaa
aggaatgtggaacacaaagtgtctgccattaaaaacagtgtgcagatgacagaacaagat
accaaatacttagaagacctgcaagatgagtttgactacaggtataaaacaattcagaca
atggatcagggtgacaaaaacagtatcctggtgaaccaggaagttttgacgctgcaagaa
atgcttaatagtctggacttcaagagaaaggaagcactcagtaagatgacgcagatagtg
aacgagacagacctgctcatgaacagcatgcttctagaagagctgcaggactggaaaaag
cggcagcagattgcctgcattggtggcccgctccacaatgggctggaccagcttcagaac
tgctttaccctactggcagagagtcttttccaactcagacagcaactggagaaactacag
gagcaatctactaaaatgacctatgaaggggatcccatccctgctcaaagagcacacctc
ctggaaagagctaccttcctgatctacaaccttttcaagaactcatttgtggtcgagcga
cagccatgcatgccaacgcaccctcagaggccgatggtacttaaaaccctcattcagttc
actgtaaaactgagattactaataaaattgccggaactaaactatcaggtgaaagtaaag
gcgtccattgacaagaatgtttcaactctaagcaatagaagatttgtgctttgtggaact
cacgtcaaagctatgtccagtgaggaatcttccaatgggagcctctcagtggagtttaga
catttgcaacccaaggagatgaagtgcagtactgggagtaaaggaaacgagggctgccac
atggtgacagaggagttgcattccataacctttgagacccagatctgcctctatggcctc
accattaacctagagaccagctcattacctgtcgtgatgatttctaatgtcagccaacta
cctaatgcatgggcatccatcatttggtacaatgtatcaactaacgactcccagaacttg
gttttctttaataaccctccatctgtcactttgggccaactcctggaagtgatgagctgg
caattttcatcctatgtcggtcgtggccttaattcagagcagctcaacatgctggcagag
aagctcacagttcagtctaactacaatgatggtcacctcacctgggccaagttctgcaag
gaacatttgcctggcaaaacatttaccttctggacttggcttgaagcaatattggaccta
attaaaaaacatattcttcccctctggattgatgggtacatcatgggatttgttagtaaa
gagaaggaacggcttctgctcaaagataaaatgcctgggacatttttgttaagattcagt
gagagccatcttggagggataaccttcacctgggtggaccaatctgaaaatggagaagtg
agattccactctgtagaaccctacaacaaagggagactgtcggctctgccgttcgctgac
atcctgcgagactacaaggttatcatggctgaaaacatccctgaaaaccctctgaagtac
ctctaccctgacattcccaaagacaaagcctttggcaaacactacagctcccagccgtgc
gaagtctcaagaccaaccgaacggggagacaagggttacgtcccctctgtttttatcccc
atttcaacaatccgaagcgattccacggagccacaatctccttcagaccttctccccatg
tctccaagtgcatatgctgtgctgagagaaaacctgagcccaacgacaattgaaactgca
atgaattccccatattctgctgaatga

KEGG   Mus musculus (mouse): 20850
Entry
20850             CDS       T01002                                 

Gene name
Stat5a, AA959963, STA, STAT5
Definition
(RefSeq) signal transducer and activator of transcription 5A
  KO
K11223  signal transducer and activator of transcription 5A
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04012  ErbB signaling pathway
mmu04217  Necroptosis
mmu04630  JAK-STAT signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04917  Prolactin signaling pathway
mmu04933  AGE-RAGE signaling pathway in diabetic complications
mmu04935  Growth hormone synthesis, secretion and action
mmu05161  Hepatitis B
mmu05162  Measles
mmu05166  Human T-cell leukemia virus 1 infection
mmu05200  Pathways in cancer
mmu05203  Viral carcinogenesis
mmu05220  Chronic myeloid leukemia
mmu05221  Acute myeloid leukemia
mmu05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    20850 (Stat5a)
   04630 JAK-STAT signaling pathway
    20850 (Stat5a)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    20850 (Stat5a)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    20850 (Stat5a)
   04659 Th17 cell differentiation
    20850 (Stat5a)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    20850 (Stat5a)
   04935 Growth hormone synthesis, secretion and action
    20850 (Stat5a)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20850 (Stat5a)
   05203 Viral carcinogenesis
    20850 (Stat5a)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    20850 (Stat5a)
   05220 Chronic myeloid leukemia
    20850 (Stat5a)
   05223 Non-small cell lung cancer
    20850 (Stat5a)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    20850 (Stat5a)
   05161 Hepatitis B
    20850 (Stat5a)
   05162 Measles
    20850 (Stat5a)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    20850 (Stat5a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20850 (Stat5a)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    20850 (Stat5a)
SSDB
Motif
Pfam: STAT_bind STAT_alpha STAT_int SH2 Flu_B_NS1
Other DBs
NCBI-GeneID: 20850
NCBI-ProteinID: NP_035618
MGI: 103036
Ensembl: ENSMUSG00000004043
Vega: OTTMUSG00000002125
UniProt: P42230 Q9JIA0 Q3UZ79
Structure
PDB: 
1Y1U

Position
11 D; 11 63.77 cM
AA seq 793 aa
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRGQATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV
REANNCSSPAGVLVDAMSQKHLQINQRFEELRLITQDTENELKKLQQTQEYFIIQYQESL
RIQAQFAQLGQLNPQERMSRETALQQKQVSLETWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNI
SSNHLEDYNSMSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPDRNLWNLKPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVFAKYYTPVLAKAVDGYVKPQIKQVVPEFVNASTDAGASATYM
DQAPSPVVCPQPHYNMYPPNPDPVLDQDGEFDLDESMDVARHVEELLRRPMDSLDARLSP
PAGLFTSARSSLS
NT seq 2382 nt   +upstreamnt  +downstreamnt
atggcgggctggattcaggcccagcagcttcagggagatgccctgcgccagatgcaagtg
ttgtatgggcagcatttccccatcgaggtccggcactacctggcccagtggatcgagagc
cagccgtgggatgctattgacttggataatccccaggaccgaggtcaggccacccaactc
ctggagggcctggtgcaggagctgcagaagaaggcggagcaccaggtgggggaagatggg
tttttgctgaagatcaagctggggcactatgccacacagctccagaacacgtatgaccgc
tgtcccatggagctggttcgctgtatccgtcacattctgtacaacgaacagaggctggtt
cgcgaagccaacaattgcagctcccctgctggtgtcctggttgacgccatgtcccagaag
caccttcagatcaaccaaaggtttgaggagctgcgcctgatcacacaggacacggagaac
gagctgaagaagctgcagcagacccaagagtacttcatcatccagtaccaggagagcctg
cggatccaagctcagtttgcccagctgggccagctgaacccccaggagcgcatgagcagg
gagacggccctccagcagaagcaagtgtccctggagacctggctgcagcgagaggcacag
acactgcagcagtaccgagtggagctggctgagaagcaccagaagaccctgcagctgctg
cggaagcagcagaccatcatcctggacgacgagctgatccagtggaagcggagacagcag
ctggccgggaacgggggtccccccgagggcagcctggacgtgctgcagtcctggtgtgag
aagctggccgagatcatctggcagaaccggcagcagatccgcagggctgagcacctgtgc
cagcagctgcccatcccaggccccgtggaggagatgctggctgaggtcaacgccaccatc
acggacatcatctcagctctggtcaccagcacgttcatcatcgagaagcagcctcctcag
gtcctgaagacccagaccaagtttgcggccaccgtgcgcctgctggtggggggaaagctg
aatgtgcacatgaaccccccgcaggtgaaggcgaccatcatcagcgagcagcaggccaag
tccctgctcaagaatgagaacacccgcaatgagtgcagcggcgagatcctgaacaactgt
tgcgtcatggagtaccaccaggccactggcacgctcagcgcccacttcagaaacatgtca
ctgaaaagaatcaagcgcgccgacaggcgtggtgcagagtcggtgacggaggagaagttc
acagtcctgtttgagtctcagttcagcgttggcagcaacgagctggtgttccaggtgaag
accctgtccctccctgtggtcgttatcgtccatggcagccaggaccacaatgctactgcc
accgtgctgtgggacaatgcctttgctgagccgggcagggtgccatttgctgtgcctgac
aaggtgctgtggccgcagctgtgtgaagcgctcaacatgaaattcaaggctgaagtacag
agcaaccggggcttgaccaaagagaacctcgtgttcctggcacagaaactgttcaacatc
agcagcaaccacctcgaggactacaacagcatgtctgtgtcctggtcccagttcaaccgg
gagaacttgcccggctggaactacaccttctggcagtggttcgacggggtgatggaggtg
ctgaagaagcaccataagccccattggaatgatggggctatcctgggtttcgtgaacaag
caacaggcccacgacctgctcatcaacaagccggacgggaccttcctgctgcgcttcagt
gactcggaaatcgggggcatcaccattgcttggaagtttgactctccggaccgaaacctc
tggaatctgaagccattcacgacgcgagatttctccattcggtccctggccgaccggctg
ggggacctgaactaccttatctacgtgttcccagaccgacccaaggacgaggtctttgcc
aagtattacactcctgtacttgcgaaagcagttgacggatacgtgaagccacagatcaag
caagtggtccctgagttcgtcaatgcatccacagatgccggagccagcgccacctacatg
gaccaggctccttccccagtcgtgtgccctcaacctcactacaacatgtacccacccaac
cctgaccctgtccttgaccaagatggcgagtttgacctggatgagagcatggatgttgcc
aggcacgtggaagaacttttacgccggcccatggacagtctcgacgcccgcctctcccca
cctgctggtctcttcacctccgctagaagctccctgtcctga

KEGG   Mus musculus (mouse): 20851
Entry
20851             CDS       T01002                                 

Gene name
Stat5b
Definition
(RefSeq) signal transducer and activator of transcription 5B
  KO
K11224  signal transducer and activator of transcription 5B
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04012  ErbB signaling pathway
mmu04062  Chemokine signaling pathway
mmu04217  Necroptosis
mmu04630  JAK-STAT signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04917  Prolactin signaling pathway
mmu04933  AGE-RAGE signaling pathway in diabetic complications
mmu04935  Growth hormone synthesis, secretion and action
mmu05161  Hepatitis B
mmu05162  Measles
mmu05166  Human T-cell leukemia virus 1 infection
mmu05200  Pathways in cancer
mmu05203  Viral carcinogenesis
mmu05220  Chronic myeloid leukemia
mmu05221  Acute myeloid leukemia
mmu05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    20851 (Stat5b)
   04630 JAK-STAT signaling pathway
    20851 (Stat5b)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    20851 (Stat5b)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    20851 (Stat5b)
   04659 Th17 cell differentiation
    20851 (Stat5b)
   04062 Chemokine signaling pathway
    20851 (Stat5b)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    20851 (Stat5b)
   04935 Growth hormone synthesis, secretion and action
    20851 (Stat5b)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20851 (Stat5b)
   05203 Viral carcinogenesis
    20851 (Stat5b)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    20851 (Stat5b)
   05220 Chronic myeloid leukemia
    20851 (Stat5b)
   05223 Non-small cell lung cancer
    20851 (Stat5b)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    20851 (Stat5b)
   05161 Hepatitis B
    20851 (Stat5b)
   05162 Measles
    20851 (Stat5b)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    20851 (Stat5b)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20851 (Stat5b)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    20851 (Stat5b)
SSDB
Motif
Pfam: STAT_bind STAT_alpha STAT_int SH2
Other DBs
NCBI-GeneID: 20851
NCBI-ProteinID: NP_001107035
MGI: 103035
Ensembl: ENSMUSG00000020919
Vega: OTTMUSG00000002127
UniProt: P42232
Position
11 D; 11 63.63 cM
AA seq 786 aa
MAMWIQAQQLQGDALHQMQALYGQHFPIEVRHYLSQWIESQAWDSIDLDNPQENIKATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQSTYDRCPMELVRCIRHILYNEQRLV
REANNGSSPAGSLADAMSQKHLQINQTFEELRLITQDTENELKKLQQTQEYFIIQYQESL
RIQAQFAQLGQLNPQERMSRETALQQKQVSLETWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRSDRRGAESVTEEKFTILFDSQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNI
SSNHLEDYNSMSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVYSKYYTPVPCEPATAKAADGYVKPQIKQVVPEFANASTDAGS
GATYMDQAPSPVVCPQAHYNMYPPNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQW
IPHAQS
NT seq 2361 nt   +upstreamnt  +downstreamnt
atggctatgtggatacaggctcagcagctccagggcgatgcccttcaccagatgcaggcc
ttgtacggccagcatttccccatcgaggtgcgacattatttatcacagtggatcgaaagc
caagcctgggactcaatagatcttgataatccacaggagaacattaaggccacccagctc
ctggagggcctggtgcaggagctgcagaagaaggcggagcaccaggtgggggaagatggg
tttttgctgaagatcaagctggggcactatgccacacagctccagagcacgtacgaccgc
tgccccatggagctggttcgctgtatccggcacattctgtacaacgaacagaggctggtt
cgcgaagccaacaacggcagctctccagctggaagtcttgctgacgccatgtcccagaag
caccttcagatcaaccaaacgtttgaggagctgcgcctgatcacacaggacacggagaac
gagctgaagaagctgcagcagacccaagagtacttcatcatccagtaccaggagagcctg
cggatccaagctcagtttgcccagctgggacagctgaacccccaggagcgcatgagcagg
gagacggccctccagcagaagcaagtgtccctggagacctggctgcagcgagaggcacag
acactgcagcagtaccgagtggagctggctgagaagcaccagaagaccctgcagctgctg
cggaagcagcagaccatcatcctggacgacgagctgatccagtggaagcggagacagcag
ctggccgggaacgggggtccccccgagggcagcctggacgtgctgcagtcctggtgtgag
aagctggccgagatcatctggcagaaccggcagcagatccgcagggctgagcacttgtgc
cagcagctgcccatcccaggccccgtggaggagatgctggctgaggtcaacgccaccatc
acggacatcatctcagccctggtcaccagcacgttcatcatcgagaagcagcctcctcag
gtcctgaagacccagaccaagtttgcagccaccgtgcgcctgctggtgggggggaagctg
aatgtgcacatgaaccccccgcaggtgaaggcgaccatcatcagcgagcagcaggccaag
tccctgctcaagaatgagaacacccgcaatgattacagcggcgagatcctgaacaactgt
tgcgtcatggagtaccaccaggccactggcacactcagcgcccacttcagaaacatgtcc
ctgaaacgaatcaagaggtctgaccgccgtggggcagagtcagtaacggaagagaagttc
acgatcctgtttgactcacagttcagcgtcggtggaaacgagctggtctttcaagtcaag
accttgtcgctcccggtggtggtgattgttcacggcagccaggacaacaatgccacagcc
actgtcctctgggacaacgcctttgcagagcctggcagggtgccatttgccgtgcctgac
aaggtgctgtggccgcagctgtgtgaagcgctcaacatgaaattcaaggctgaagtacag
agcaaccggggcttgaccaaggagaacctcgtgttcctggcacagaaactgttcaacatc
agcagcaaccacctcgaggactacaacagcatgtccgtgtcctggtcccagttcaaccgg
gagaatttgccaggacggaattacactttctggcagtggtttgatggcgtgatggaagta
ttgaaaaaacatctcaagcctcactggaatgatggggctatcctgggtttcgtgaacaag
caacaggcccacgacctgctcatcaacaagccagacgggaccttcctgctgcgcttcagc
gactcggaaatcgggggcatcaccattgcttggaagtttgactctcaggagagaatgttt
tggaatctgatgccttttaccactagagacttctctatccggtccctcgctgaccgcctg
ggggacctgaattacctcatatatgtgtttcctgatcggccaaaggatgaagtatattct
aagtactacacaccggtcccctgtgagcccgcaactgcgaaagcagctgacggatacgtg
aagccacagatcaagcaggtggtccccgagtttgcaaatgcatccacagatgctgggagt
ggcgccacctacatggatcaggctccttccccagtcgtgtgccctcaggctcactacaac
atgtacccacccaacccggactccgtccttgataccgatggggacttcgatctggaagac
acgatggacgtggcgcggcgcgtggaagagctcttaggccggcccatggacagtcagtgg
atccctcacgcacagtcatga

KEGG   Mus musculus (mouse): 20852
Entry
20852             CDS       T01002                                 

Gene name
Stat6
Definition
(RefSeq) signal transducer and activator of transcription 6
  KO
K11225  signal transducer and activator of transcription 6
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04217  Necroptosis
mmu04630  JAK-STAT signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu05161  Hepatitis B
mmu05200  Pathways in cancer
mmu05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    20852 (Stat6)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    20852 (Stat6)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    20852 (Stat6)
   04659 Th17 cell differentiation
    20852 (Stat6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20852 (Stat6)
  09172 Infectious disease: viral
   05161 Hepatitis B
    20852 (Stat6)
  09163 Immune disease
   05321 Inflammatory bowel disease
    20852 (Stat6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20852 (Stat6)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    20852 (Stat6)
SSDB
Motif
Pfam: STAT6_C STAT_bind STAT_int STAT_alpha SH2
Other DBs
NCBI-GeneID: 20852
NCBI-ProteinID: NP_033310
MGI: 103034
Ensembl: ENSMUSG00000002147
Vega: OTTMUSG00000031818
UniProt: P52633
Position
10 D3; 10 74.59 cM
AA seq 837 aa
MSLWGLISKMSPEKLQRLYVDFPQRLRHLLADWLESQPWEFLVGSDAFCYNMASALLSAT
VQRLQATAGEQGKGNSILPHISTLESIYQRDPLKLVATIRQILQGEKKAVIEEFRHLPGP
FHRKQEELKFTTALGRLQHRVRETRLLRESLQQGAKTGQVSLQNLIDPPVNGPGPSEDLA
TMLQGTVGDLEATQALVLKRIQIWKRQQQLAGNGTPFEESLAGLQERCESLVEIYSQLQQ
EIGAASGELEPKTRASLISRLDEVLRTLVTSSFLVEKQPPQVLKTQTKFQAGVRFLLGLQ
FLGTSAKPPMVRADMVTEKQARELSLAQGPGTGVESTGEIMNNTVPLENSIPSNCCSALF
KNLLLKKIKRCERKGTESVTEEKCAVLFSTSFTLGPNKLLIQLQALSLPLVVIVHGNQDN
NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTSRGLLPEHFLFLAQK
IFNDNSLSVEAFQHRCVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSSQIENIQPFSAKDLSIR
SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVSTTIKMTVERDQPLPTPE
PQMPAMVPPYDLGMAPDASMQLSSDMGYPPQSIHSFQSLEESMSVLPSFQEPHLQMPPNM
SQITMPFDQPHPQGLLQCQSQEHAVSSPEPMLCSDVTMVEDSCLTQPVGGFPQGTWVSED
MYPPLMPPTEQDLTKLLLENQGEAGGSLGSQPLLQPSPYGQSGISLSHLDLRTNPSW
NT seq 2514 nt   +upstreamnt  +downstreamnt
atgtctctgtggggcctaatttccaagatgtccccagaaaaactgcaacggctctatgtt
gactttccacaacgcctacggcatctcctggctgactggctggagagccagccctgggag
ttcctggtcggttcagatgctttctgttacaacatggccagtgccctactttctgccaca
gtccagcgtcttcaggccactgctggagagcaggggaagggaaacagcatcttgccgcac
atcagcaccttggagagcatctatcagagggaccccctgaagctggtggccaccatcaga
caaatacttcaaggggagaaaaaagctgttatagaagagttccgccacctgccagggccc
ttccatcggaagcaggaagaactcaagtttactacagccctcggaaggcttcagcatcga
gtaagggagacccggcttctccgagaatctctgcagcaaggggctaagactggacaagtg
tctctgcagaatttgatagaccctcctgtcaatggtcctggtccaagtgaggacctggcc
accatgctgcaggggactgtgggggacctggaggccacccaggccctggtgctgaaaagg
attcagatttggaagcggcagcaacagctggcagggaatggcacaccctttgaggagagc
ctagcagggctgcaggagaggtgtgaaagcctggtggaaatttattcccagctgcagcag
gagattggggcagccagtggagaactggaacccaagacccgggcatcgctgataagccgt
ctggatgaagtcctgcgaacccttgtgaccagctctttcctggtggagaagcagcccccg
caggttctgaagacacagactaagttccaggctggggttcgattcctgctgggtctgcag
tttctagggacctcagccaagcctccaatggtcagagctgacatggtgacagagaaacag
gccagagaactaagcctggcccaggggcccgggactggagtggagagcacaggagagatc
atgaacaacacggtgcccctggagaacagcattcccagcaactgctgctccgccctgttc
aagaacctgctcctgaagaaaataaagcgctgtgagcggaagggcacagagtctgtcacc
gaggagaagtgtgctgtgctcttctccacgagcttcacattgggccccaacaaacttctc
atccagcttcaggccctgtctctgcccttggtggtcatcgtgcatggtaaccaagacaac
aacgccaaagctaccatcctatgggacaatgccttctctgagatggaccgagtgcccttt
gtggtggctgagcgagtgccctgggagaagatgtgtgaaaccctaaacctcaagtttatg
gctgaggtggggaccagccggggactgcttccagagcacttcctgttcctcgcccagaag
atcttcaacgacaacagcctcagtgtggaggcctttcagcaccgctgtgtgtcctggtca
cagttcaataaggagatcctgctgggccgaggcttcacattttggcagtggtttgatggt
gtcctggacctcaccaaacgctgtctccggagctactggtcagatcggctgatcattggc
tttattagtaagcaatatgtcactagccttctcctcaatgagccagatgggaccttcctc
ctccgctttagcgactctgagatcgggggcatcaccattgcacacgtcatccggggtcag
gatggctcctcacagatagagaacatccagccattttctgccaaagacctgtccattcgc
tcactgggggaccggatccgggatcttgctcagttaaaaaacctctaccccaagaaaccc
aaagatgaggctttccggagtcactataagcccgaacagatggggaaggacgggaggggt
tatgtctctactactatcaagatgactgtggaaagggaccagccccttcctactccagag
ccccagatgcctgccatggtgccaccttatgatcttggaatggcccctgatgcttccatg
caactcagctcagatatggggtatcctccacagtccatccactcatttcagagcctagaa
gagtccatgagtgtactgccatcttttcaggagcctcacctgcaaatgccccccaacatg
agccagataaccatgccctttgaccagcctcacccccagggtctgctgcagtgccagtcc
caggaacatgctgtgtccagccctgaacccatgctttgctcagatgtgactatggtagag
gacagctgcctaactcagcctgtgggaggtttcccccaaggcacctgggtcagtgaagac
atgtaccctcccctgatgcctcccactgaacaggacctcaccaagcttctcctggagaac
caaggggaggcaggagggtccttaggaagccagcccctcctgcaaccatctccttatggg
caatcagggatctcactgtcccacctggacctaaggaccaaccccagctggtga

DBGET integrated database retrieval system