KEGG   Mus musculus (mouse): 20849Help
Entry
20849             CDS       T01002                                 

Gene name
Stat4
Definition
(RefSeq) signal transducer and activator of transcription 4
  KO
K11222  signal transducer and activator of transcription 4
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04217  Necroptosis
mmu04630  Jak-STAT signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu05161  Hepatitis B
mmu05200  Pathways in cancer
mmu05321  Inflammatory bowel disease (IBD)
Module
mmu_M00684  JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    20849 (Stat4)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    20849 (Stat4)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    20849 (Stat4)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    20849 (Stat4)
  09163 Immune diseases
   05321 Inflammatory bowel disease (IBD)
    20849 (Stat4)
  09172 Infectious diseases: Viral
   05161 Hepatitis B
    20849 (Stat4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20849 (Stat4)
Transcription factors [BR:mmu03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   STAT
    20849 (Stat4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: STAT_alpha STAT_int STAT_bind SH2 NPV_P10 Prp19 CRC_subunit
Motif
Other DBs
NCBI-GeneID: 20849
NCBI-ProteinID: NP_001295195
MGI: 103062
Ensembl: ENSMUSG00000062939
Vega: OTTMUSG00000046732
UniProt: P42228 Q3V157
Structure
PDB: 

Position
1 C1.1; 1 26.67 cM
AA seq 748 aa AA seqDB search
MSQWNQVQQLEIKFLEQVDQFYDDNFPMEIRHLLAQWIETQDWEVASNNETMATILLQNL
LIQLDEQLGRVSKEKNLLLIHNLKRIRKVLQGKFHGNPMHVAVVISNCLREERRILAAAN
MPIQGPLEKSLQSSSVSERQRNVEHKVSAIKNSVQMTEQDTKYLEDLQDEFDYRYKTIQT
MDQGDKNSILVNQEVLTLQEMLNSLDFKRKEALSKMTQIVNETDLLMNSMLLEELQDWKK
RQQIACIGGPLHNGLDQLQNCFTLLAESLFQLRQQLEKLQEQSTKMTYEGDPIPAQRAHL
LERATFLIYNLFKNSFVVERQPCMPTHPQRPMVLKTLIQFTVKLRLLIKLPELNYQVKVK
ASIDKNVSTLSNRRFVLCGTHVKAMSSEESSNGSLSVEFRHLQPKEMKCSTGSKGNEGCH
MVTEELHSITFETQICLYGLTINLETSSLPVVMISNVSQLPNAWASIIWYNVSTNDSQNL
VFFNNPPSVTLGQLLEVMSWQFSSYVGRGLNSEQLNMLAEKLTVQSNYNDGHLTWAKFCK
EHLPGKTFTFWTWLEAILDLIKKHILPLWIDGYIMGFVSKEKERLLLKDKMPGTFLLRFS
ESHLGGITFTWVDQSENGEVRFHSVEPYNKGRLSALPFADILRDYKVIMAENIPENPLKY
LYPDIPKDKAFGKHYSSQPCEVSRPTERGDKGYVPSVFIPISTIRSDSTEPQSPSDLLPM
SPSAYAVLRENLSPTTIETAMNSPYSAE
NT seq 2247 nt NT seq  +upstreamnt  +downstreamnt
atgtctcagtggaatcaagtccaacaattagaaatcaagtttttggagcaagtagatcag
ttctatgatgacaactttcctatggaaatccggcatctgctagctcagtggattgagact
caagactgggaagtagcttctaacaatgaaactatggcaacaattctgcttcaaaactta
ctaatacaattggatgaacagttggggcgtgtttccaaagaaaaaaatctgctattgatt
cacaatctaaagagaattagaaaagttcttcagggcaagtttcatggaaatccaatgcat
gtagctgtggtaatttcaaattgcttaagggaagagaggagaatattggctgcagccaac
atgcctatccagggacctctggagaaatccttacagagttcttcagtttctgaaagacaa
aggaatgtggaacacaaagtgtctgccattaaaaacagtgtgcagatgacagaacaagat
accaaatacttagaagacctgcaagatgagtttgactacaggtataaaacaattcagaca
atggatcagggtgacaaaaacagtatcctggtgaaccaggaagttttgacgctgcaagaa
atgcttaatagtctggacttcaagagaaaggaagcactcagtaagatgacgcagatagtg
aacgagacagacctgctcatgaacagcatgcttctagaagagctgcaggactggaaaaag
cggcagcagattgcctgcattggtggcccgctccacaatgggctggaccagcttcagaac
tgctttaccctactggcagagagtcttttccaactcagacagcaactggagaaactacag
gagcaatctactaaaatgacctatgaaggggatcccatccctgctcaaagagcacacctc
ctggaaagagctaccttcctgatctacaaccttttcaagaactcatttgtggtcgagcga
cagccatgcatgccaacgcaccctcagaggccgatggtacttaaaaccctcattcagttc
actgtaaaactgagattactaataaaattgccggaactaaactatcaggtgaaagtaaag
gcgtccattgacaagaatgtttcaactctaagcaatagaagatttgtgctttgtggaact
cacgtcaaagctatgtccagtgaggaatcttccaatgggagcctctcagtggagtttaga
catttgcaacccaaggagatgaagtgcagtactgggagtaaaggaaacgagggctgccac
atggtgacagaggagttgcattccataacctttgagacccagatctgcctctatggcctc
accattaacctagagaccagctcattacctgtcgtgatgatttctaatgtcagccaacta
cctaatgcatgggcatccatcatttggtacaatgtatcaactaacgactcccagaacttg
gttttctttaataaccctccatctgtcactttgggccaactcctggaagtgatgagctgg
caattttcatcctatgtcggtcgtggccttaattcagagcagctcaacatgctggcagag
aagctcacagttcagtctaactacaatgatggtcacctcacctgggccaagttctgcaag
gaacatttgcctggcaaaacatttaccttctggacttggcttgaagcaatattggaccta
attaaaaaacatattcttcccctctggattgatgggtacatcatgggatttgttagtaaa
gagaaggaacggcttctgctcaaagataaaatgcctgggacatttttgttaagattcagt
gagagccatcttggagggataaccttcacctgggtggaccaatctgaaaatggagaagtg
agattccactctgtagaaccctacaacaaagggagactgtcggctctgccgttcgctgac
atcctgcgagactacaaggttatcatggctgaaaacatccctgaaaaccctctgaagtac
ctctaccctgacattcccaaagacaaagcctttggcaaacactacagctcccagccgtgc
gaagtctcaagaccaaccgaacggggagacaagggttacgtcccctctgtttttatcccc
atttcaacaatccgaagcgattccacggagccacaatctccttcagaccttctccccatg
tctccaagtgcatatgctgtgctgagagaaaacctgagcccaacgacaattgaaactgca
atgaattccccatattctgctgaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (27)   
   RefSeq(nuc) (5)   
   GenBank (11)   
   EMBL (11)   
Protein domain (7)   
   Pfam (7)   
All databases (70)   

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