KEGG   Mus musculus (house mouse): 20850
Entry
20850             CDS       T01002                                 
Symbol
Stat5a, STAT5
Name
(RefSeq) signal transducer and activator of transcription 5A isoform 1
  KO
K11223  signal transducer and activator of transcription 5A
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04012  ErbB signaling pathway
mmu04081  Hormone signaling
mmu04217  Necroptosis
mmu04630  JAK-STAT signaling pathway
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04917  Prolactin signaling pathway
mmu04933  AGE-RAGE signaling pathway in diabetic complications
mmu04935  Growth hormone synthesis, secretion and action
mmu05161  Hepatitis B
mmu05162  Measles
mmu05166  Human T-cell leukemia virus 1 infection
mmu05200  Pathways in cancer
mmu05203  Viral carcinogenesis
mmu05207  Chemical carcinogenesis - receptor activation
mmu05220  Chronic myeloid leukemia
mmu05221  Acute myeloid leukemia
mmu05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    20850 (Stat5a)
   04630 JAK-STAT signaling pathway
    20850 (Stat5a)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    20850 (Stat5a)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    20850 (Stat5a)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    20850 (Stat5a)
   04659 Th17 cell differentiation
    20850 (Stat5a)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    20850 (Stat5a)
   04935 Growth hormone synthesis, secretion and action
    20850 (Stat5a)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    20850 (Stat5a)
   05207 Chemical carcinogenesis - receptor activation
    20850 (Stat5a)
   05203 Viral carcinogenesis
    20850 (Stat5a)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    20850 (Stat5a)
   05220 Chronic myeloid leukemia
    20850 (Stat5a)
   05223 Non-small cell lung cancer
    20850 (Stat5a)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    20850 (Stat5a)
   05161 Hepatitis B
    20850 (Stat5a)
   05162 Measles
    20850 (Stat5a)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    20850 (Stat5a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    20850 (Stat5a)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    20850 (Stat5a)
SSDB
Motif
Pfam: STAT_bind STAT_alpha STAT_int STAT_linker SH2 Flu_B_NS1
Other DBs
NCBI-GeneID: 20850
NCBI-ProteinID: NP_001349609
MGI: 103036
Ensembl: ENSMUSG00000004043
UniProt: P42230 Q9JIA0
Structure
Position
11:100750177..100775995
AA seq 793 aa
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRGQATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV
REANNCSSPAGVLVDAMSQKHLQINQRFEELRLITQDTENELKKLQQTQEYFIIQYQESL
RIQAQFAQLGQLNPQERMSRETALQQKQVSLETWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNI
SSNHLEDYNSMSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPDRNLWNLKPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVFAKYYTPVLAKAVDGYVKPQIKQVVPEFVNASTDAGASATYM
DQAPSPVVCPQPHYNMYPPNPDPVLDQDGEFDLDESMDVARHVEELLRRPMDSLDARLSP
PAGLFTSARSSLS
NT seq 2382 nt   +upstreamnt  +downstreamnt
atggcgggctggattcaggcccagcagcttcagggagatgccctgcgccagatgcaagtg
ttgtatgggcagcatttccccatcgaggtccggcactacctggcccagtggatcgagagc
cagccgtgggatgctattgacttggataatccccaggaccgaggtcaggccacccaactc
ctggagggcctggtgcaggagctgcagaagaaggcggagcaccaggtgggggaagatggg
tttttgctgaagatcaagctggggcactatgccacacagctccagaacacgtatgaccgc
tgtcccatggagctggttcgctgtatccgtcacattctgtacaacgaacagaggctggtt
cgcgaagccaacaattgcagctcccctgctggtgtcctggttgacgccatgtcccagaag
caccttcagatcaaccaaaggtttgaggagctgcgcctgatcacacaggacacggagaac
gagctgaagaagctgcagcagacccaagagtacttcatcatccagtaccaggagagcctg
cggatccaagctcagtttgcccagctgggccagctgaacccccaggagcgcatgagcagg
gagacggccctccagcagaagcaagtgtccctggagacctggctgcagcgagaggcacag
acactgcagcagtaccgagtggagctggctgagaagcaccagaagaccctgcagctgctg
cggaagcagcagaccatcatcctggacgacgagctgatccagtggaagcggagacagcag
ctggccgggaacgggggtccccccgagggcagcctggacgtgctgcagtcctggtgtgag
aagctggccgagatcatctggcagaaccggcagcagatccgcagggctgagcacctgtgc
cagcagctgcccatcccaggccccgtggaggagatgctggctgaggtcaacgccaccatc
acggacatcatctcagctctggtcaccagcacgttcatcatcgagaagcagcctcctcag
gtcctgaagacccagaccaagtttgcggccaccgtgcgcctgctggtggggggaaagctg
aatgtgcacatgaaccccccgcaggtgaaggcgaccatcatcagcgagcagcaggccaag
tccctgctcaagaatgagaacacccgcaatgagtgcagcggcgagatcctgaacaactgt
tgcgtcatggagtaccaccaggccactggcacgctcagcgcccacttcagaaacatgtca
ctgaaaagaatcaagcgcgccgacaggcgtggtgcagagtcggtgacggaggagaagttc
acagtcctgtttgagtctcagttcagcgttggcagcaacgagctggtgttccaggtgaag
accctgtccctccctgtggtcgttatcgtccatggcagccaggaccacaatgctactgcc
accgtgctgtgggacaatgcctttgctgagccgggcagggtgccatttgctgtgcctgac
aaggtgctgtggccgcagctgtgtgaagcgctcaacatgaaattcaaggctgaagtacag
agcaaccggggcttgaccaaagagaacctcgtgttcctggcacagaaactgttcaacatc
agcagcaaccacctcgaggactacaacagcatgtctgtgtcctggtcccagttcaaccgg
gagaacttgcccggctggaactacaccttctggcagtggttcgacggggtgatggaggtg
ctgaagaagcaccataagccccattggaatgatggggctatcctgggtttcgtgaacaag
caacaggcccacgacctgctcatcaacaagccggacgggaccttcctgctgcgcttcagt
gactcggaaatcgggggcatcaccattgcttggaagtttgactctccggaccgaaacctc
tggaatctgaagccattcacgacgcgagatttctccattcggtccctggccgaccggctg
ggggacctgaactaccttatctacgtgttcccagaccgacccaaggacgaggtctttgcc
aagtattacactcctgtacttgcgaaagcagttgacggatacgtgaagccacagatcaag
caagtggtccctgagttcgtcaatgcatccacagatgccggagccagcgccacctacatg
gaccaggctccttccccagtcgtgtgccctcaacctcactacaacatgtacccacccaac
cctgaccctgtccttgaccaagatggcgagtttgacctggatgagagcatggatgttgcc
aggcacgtggaagaacttttacgccggcccatggacagtctcgacgcccgcctctcccca
cctgctggtctcttcacctccgctagaagctccctgtcctga

  All links  
Gene (10)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (37)   
   RefSeq(nuc) (5)   
   GenBank (16)   
   EMBL (16)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (63)   

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