KEGG   Mus musculus (house mouse): 208715
Entry
208715            CDS       T01002                                 
Symbol
Hmgcs1, B130032C06Rik
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
  KO
K01641  hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00280  Valine, leucine and isoleucine degradation
mmu00650  Butanoate metabolism
mmu00900  Terpenoid backbone biosynthesis
mmu01100  Metabolic pathways
mmu03320  PPAR signaling pathway
Module
mmu_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    208715 (Hmgcs1)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    208715 (Hmgcs1)
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    208715 (Hmgcs1)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    208715 (Hmgcs1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.10  hydroxymethylglutaryl-CoA synthase
     208715 (Hmgcs1)
SSDB
Motif
Pfam: HMG_CoA_synt_C HMG_CoA_synt_N Cullin
Other DBs
NCBI-GeneID: 208715
NCBI-ProteinID: NP_001278368
MGI: 107592
Ensembl: ENSMUSG00000093930
UniProt: Q8JZK9
Position
13:120151887..120169796
AA seq 520 aa
MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCT
DREDINSLCLTVVQKLMERHSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDI
EGIDTTNACYGGTAAVFNAVNWVESSSWDGRYALVVAGDIAIYATGNARPTGGVGAVALL
IGPNAPLIFDRGLRGTHMQHAYDFYKPDMLSEYPVVDGKLSIQCYLSALDRCYSVYRKKI
RAQWQKEGKDKDFTLNDFGFMIFHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEA
FGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQY
SPQQLAGKRVGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTCVAP
DVFAENMKLREDTHHLANYIPQCSIDSLFEGTWYLVRVDEKHRRTYARRPFTNDHSLDEG
MGLVHSNTATEHIPSPAKKVPRLPATSAESESAVISNGEH
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgcctgggtcacttcctttgaatgcagaggcttgctggccaaaagatgtgggaatcgtt
gcccttgaaatctactttccttctcaatatgtcgatcaagctgagttggaaaaatacgat
ggtgtagatgctggaaagtataccatcggcctgggccaggccaggatgggcttctgcacg
gatcgtgaagacatcaactctctttgcctgactgtggttcagaaactgatggagagacat
agcctttcctatgattgcattgggcggctagaagttggaacagagacaatcatcgacaaa
tcgaaatcagtgaagtctaatttgatgcagctgtttgaggagtctgggaatacagatata
gaaggaatagatacaaccaatgcatgctatgggggcacagctgcagtcttcaatgccgtg
aactgggtcgaatccagctcttgggatggacgatatgctctggtagttgcaggagacatt
gctatatatgccacaggaaatgccagacctacaggtggagttggagctgtggccctgcta
attgggccaaacgctcctctaatttttgaccgagggctccgtgggacacacatgcagcat
gcctatgacttttacaagcctgacatgctctccgagtaccctgtggtcgacggaaagctc
tccatacagtgctacctcagcgccctggaccgctgctattctgtctaccgcaaaaagatc
cgtgcccagtggcagaaagagggaaaggataaagattttaccctgaatgattttggcttc
atgatctttcactcaccatattgtaaactggtgcagaaatctctagctcggatgttcctg
aatgactttcttaatgatcaaaacagagataaaaacagtatttacagtggactggaagcc
tttggggacgttaaattagaagatacttactttgacagagatgtagaaaaggcatttatg
aaggctagttctgagctattcaaccagaaaacaaaggcgtctttgcttgtgtctaatcag
aatggaaatatgtacacatcctctgtctatggttccctggcttctgtcctggcacagtac
tcacctcagcagttggcagggaagagggttggagtgttctcttacggttctggcttggct
gccacgctgtactcccttaaagtcacacaagacgccacaccaggatctgcccttgataaa
ataacagcaagtttatgtgaccttaaatcaaggcttgactcgagaacttgtgtggcaccg
gatgtctttgctgaaaacatgaagctcagagaggacacacatcacttagccaactatatt
ccccagtgttcaatagactcactctttgaaggaacgtggtatctggtcagagtggatgaa
aaacacagaaggacttacgcccggcgccccttcacaaatgaccacagtttggatgaagga
atggggctcgtgcatagtaacacagcaacagagcatattccaagccctgctaagaaagtg
ccaagactccctgcaacctcggccgaatctgaatcagctgtcatcagtaacggggagcac
tga

  All links  
Gene (11)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (42)   
   RefSeq(nuc) (4)   
   GenBank (19)   
   EMBL (19)   
Protein domain (3)   
   Pfam (3)   
All databases (62)   

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