KEGG   Mus musculus (mouse): 211429Help
Entry
211429            CDS       T01002                                 

Gene name
Pla2g4b, A030011C02Rik, Gm1013, cPLA2-beta
Definition
(RefSeq) phospholipase A2, group IVB (cytosolic)
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00564  Glycerophospholipid metabolism
mmu00565  Ether lipid metabolism
mmu00590  Arachidonic acid metabolism
mmu00591  Linoleic acid metabolism
mmu00592  alpha-Linolenic acid metabolism
mmu01100  Metabolic pathways
mmu04010  MAPK signaling pathway
mmu04014  Ras signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04217  Necroptosis
mmu04270  Vascular smooth muscle contraction
mmu04370  VEGF signaling pathway
mmu04611  Platelet activation
mmu04664  Fc epsilon RI signaling pathway
mmu04666  Fc gamma R-mediated phagocytosis
mmu04724  Glutamatergic synapse
mmu04726  Serotonergic synapse
mmu04730  Long-term depression
mmu04750  Inflammatory mediator regulation of TRP channels
mmu04912  GnRH signaling pathway
mmu04913  Ovarian steroidogenesis
mmu04921  Oxytocin signaling pathway
mmu05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    211429 (Pla2g4b)
   00565 Ether lipid metabolism
    211429 (Pla2g4b)
   00590 Arachidonic acid metabolism
    211429 (Pla2g4b)
   00591 Linoleic acid metabolism
    211429 (Pla2g4b)
   00592 alpha-Linolenic acid metabolism
    211429 (Pla2g4b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    211429 (Pla2g4b)
   04010 MAPK signaling pathway
    211429 (Pla2g4b)
   04370 VEGF signaling pathway
    211429 (Pla2g4b)
   04072 Phospholipase D signaling pathway
    211429 (Pla2g4b)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    211429 (Pla2g4b)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    211429 (Pla2g4b)
   04664 Fc epsilon RI signaling pathway
    211429 (Pla2g4b)
   04666 Fc gamma R-mediated phagocytosis
    211429 (Pla2g4b)
  09152 Endocrine system
   04912 GnRH signaling pathway
    211429 (Pla2g4b)
   04913 Ovarian steroidogenesis
    211429 (Pla2g4b)
   04921 Oxytocin signaling pathway
    211429 (Pla2g4b)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    211429 (Pla2g4b)
  09156 Nervous system
   04724 Glutamatergic synapse
    211429 (Pla2g4b)
   04726 Serotonergic synapse
    211429 (Pla2g4b)
   04730 Long-term depression
    211429 (Pla2g4b)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    211429 (Pla2g4b)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    211429 (Pla2g4b)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     211429 (Pla2g4b)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PLA2_B cPLA2_C2 C2
Motif
Other DBs
NCBI-GeneID: 211429
NCBI-ProteinID: NP_663353
MGI: 2384819
Ensembl: ENSMUSG00000098488
Vega: OTTMUSG00000015287
UniProt: P0C871 Q06G06 B7ZCM8
Position
2; 2 E5
AA seq 791 aa AA seqDB search
MALQTCPVYMQAKVPETCLLTVRVLRASGLPSKDLVTSSDCYVTLNLPTASSHTLQTRTV
KNSRNPVWNQNFHFRIHRQLKNVMELKVFDHDLVTRDDPVLSVLFDVGTLQIGTQRQSFS
LGTQEKGCLEVEFRLQTLTDCEEQLISNGIVVARELSCLHVELKRTGDPKRSERKVQLVV
AGACEGPQDASAGTGSFHFHYPACWEQELNVHLQDDPHEQLKVPLRTLPSSQLVRLVFPT
SQEPLMRLELKKEEGPKELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQLDQDLHEDE
IPVIAVMATGGGIRAMTSLYGQLAGLQELGLLDCISYITGASGSTWALANLYEDPEWSQK
DLAGPTEVLKTQVTKSKLGALAPSQLWRYRQELAERARLGHPTCFTNLWALINEALLHDK
PHEHKLSDQREALSRGQNPLPIYCALNSKEQGLSTFDFGEWCEFSPYEVGFPKYGAFISS
ELFGSEFFMGRLVKQLPESRICFLEGIWSNLFAASLQDSLYWSSEPSQFWDRWAQDQANL
DKEQVPHLKIAEPPTMAGRIAELFTDLLTKRPLAHATHNFTRGLHFHKDYFQNSHFSAWK
ASKLDRLPNQLTPTEPHLCLLDVGYLINTSCPPLLQPTRDVDLILSLDYNLYGAFQQLQL
LSRFCQEQGIPFPSISPSPEEQRQPQECHLFCDPAQPEAPAVLHFPLVNDSFQDYSAPGV
PRTSEEKAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLRLTHYNICNNQDRLREAMHQAVQ
RRRKRKQFRPE
NT seq 2376 nt NT seq  +upstreamnt  +downstreamnt
atggctctgcaaacctgcccagtctacatgcaggcaaaggtgccagagacatgcctgctc
actgtacgcgtcctccgggccagtggcttgccttccaaggacctagtaacctcctctgac
tgctatgtgactctgaacctgcccacggcttccagccacacgctccagacacgcacagtc
aagaacagccgaaaccctgtctggaatcagaacttccacttccggatccataggcagctc
aagaatgttatggaactgaaagtctttgaccatgacctggtgaccagagatgacccagta
ttgtcagtgctgtttgacgtggggaccctgcaaattgggactcagcgccagagcttctcc
ttgggtactcaggagaaagggtgcttagaagttgagtttcggctacagactctgacagac
tgtgaggaacagctcatcagcaatggcatcgtggtggcccgggaactctcctgcttgcac
gttgaactgaagaggacaggagatccaaagaggtcagagcgcaaagttcaacttgtggtt
gctggggcctgtgagggcccacaggatgcctctgcgggcactggatctttccacttccat
tatccagcctgctgggagcaagagctgaatgttcatctgcaggatgacccccatgagcag
ctgaaggtgccactacgaactctaccctcctcgcagctggtgagacttgtcttccccacg
tcccaggagccactgatgaggctggaactcaagaaggaagaaggaccaaaggagctggct
gtgcggctgggctgtgggccctgccctgaggaacaggccttcctaagcaagaggaagcag
gtggtggctgccgcgctgaaaaaggccttacagctggaccaagacctgcacgaggatgag
atccccgtgattgccgtgatggccactggtggtgggatccgggccatgacgtctttgtat
gggcagctggccggcctgcaggagctcggccttctcgactgcatctcctatatcacgggg
gcttcaggatccacctgggcactggccaacctctatgaggacccagagtggtcgcagaag
gacctggcagggcccactgaggtgctgaagacacaggtgacaaagagcaagctgggtgcg
ttggcccctagccaactttggcggtaccggcaagagctggctgagcgtgctcgcctgggc
cacccaacctgcttcaccaacttgtgggccctcattaatgaggccttgctgcacgacaag
ccccatgaacacaaactctcagatcaacgagaggccctgagtcgaggccagaaccctctg
cctatctattgtgccctcaacagcaaggagcagggcctgagtacctttgactttggggag
tggtgtgagttctctccatatgaagtcggcttccccaagtatggagccttcatctcctcc
gagctctttggctcggagttctttatggggcggctggtgaagcagcttcccgagtcccgc
atctgcttcctggaaggcatctggagcaatctgtttgcggccagcctccaagacagcttg
tactggtcctcagaacccagccagttctgggaccgctgggcgcaggatcaggccaacctg
gacaaagagcaggtcccccatctgaagatagcagagccaccgacaatggctggcaggatc
gccgagctcttcactgacctcctgacaaagcgtcccctcgcccacgccacccacaacttc
acgcgaggcctccatttccacaaggactatttccagaactctcacttctctgcctggaaa
gcttccaaactggacaggctccccaaccagctgacacccactgagccccacctctgcctc
ctggatgttggctatctcatcaatactagctgcccacccctcctgcagccaacacgggat
gtggacctcatcttgtcactggactacaacctctacggagcctttcagcagctgcagctt
ctgagccggttctgccaggagcagggcatccctttcccatccatctcacccagccccgag
gagcagcggcagcctcaggagtgccatctgttctgtgacccagcccagcccgaagccccg
gctgtgctgcacttccctttggtcaatgactccttccaagactactctgcccctggggtg
ccacggacatcggaggagaaggcagctggggaggtgaatctgtcttcttctgactcccca
taccactacacaaaagtgacctacagccaggaagatgtggacaagctgttacggctgacg
cattacaacatctgcaacaaccaggatcggctgcgggaggccatgcaccaggccgtgcag
cggcggagaaagcgcaaacagtttaggccggagtga

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