KEGG   Mus musculus (house mouse): 21803
Entry
21803             CDS       T01002                                 
Symbol
Tgfb1, TGF-beta1, TGFbeta1, Tgfb, Tgfb-1
Name
(RefSeq) transforming growth factor, beta 1
  KO
K13375  transforming growth factor beta-1
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04060  Cytokine-cytokine receptor interaction
mmu04068  FoxO signaling pathway
mmu04110  Cell cycle
mmu04148  Efferocytosis
mmu04218  Cellular senescence
mmu04350  TGF-beta signaling pathway
mmu04380  Osteoclast differentiation
mmu04390  Hippo signaling pathway
mmu04518  Integrin signaling
mmu04659  Th17 cell differentiation
mmu04672  Intestinal immune network for IgA production
mmu04926  Relaxin signaling pathway
mmu04932  Non-alcoholic fatty liver disease
mmu04933  AGE-RAGE signaling pathway in diabetic complications
mmu05140  Leishmaniasis
mmu05142  Chagas disease
mmu05144  Malaria
mmu05145  Toxoplasmosis
mmu05146  Amoebiasis
mmu05152  Tuberculosis
mmu05161  Hepatitis B
mmu05166  Human T-cell leukemia virus 1 infection
mmu05200  Pathways in cancer
mmu05205  Proteoglycans in cancer
mmu05210  Colorectal cancer
mmu05211  Renal cell carcinoma
mmu05212  Pancreatic cancer
mmu05220  Chronic myeloid leukemia
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
mmu05321  Inflammatory bowel disease
mmu05323  Rheumatoid arthritis
mmu05410  Hypertrophic cardiomyopathy
mmu05414  Dilated cardiomyopathy
mmu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    21803 (Tgfb1)
   04350 TGF-beta signaling pathway
    21803 (Tgfb1)
   04390 Hippo signaling pathway
    21803 (Tgfb1)
   04068 FoxO signaling pathway
    21803 (Tgfb1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    21803 (Tgfb1)
   04518 Integrin signaling
    21803 (Tgfb1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    21803 (Tgfb1)
  09143 Cell growth and death
   04110 Cell cycle
    21803 (Tgfb1)
   04218 Cellular senescence
    21803 (Tgfb1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    21803 (Tgfb1)
   04672 Intestinal immune network for IgA production
    21803 (Tgfb1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    21803 (Tgfb1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    21803 (Tgfb1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    21803 (Tgfb1)
   05205 Proteoglycans in cancer
    21803 (Tgfb1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    21803 (Tgfb1)
   05212 Pancreatic cancer
    21803 (Tgfb1)
   05225 Hepatocellular carcinoma
    21803 (Tgfb1)
   05226 Gastric cancer
    21803 (Tgfb1)
   05220 Chronic myeloid leukemia
    21803 (Tgfb1)
   05211 Renal cell carcinoma
    21803 (Tgfb1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    21803 (Tgfb1)
   05161 Hepatitis B
    21803 (Tgfb1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    21803 (Tgfb1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    21803 (Tgfb1)
   05144 Malaria
    21803 (Tgfb1)
   05145 Toxoplasmosis
    21803 (Tgfb1)
   05140 Leishmaniasis
    21803 (Tgfb1)
   05142 Chagas disease
    21803 (Tgfb1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    21803 (Tgfb1)
   05321 Inflammatory bowel disease
    21803 (Tgfb1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    21803 (Tgfb1)
   05414 Dilated cardiomyopathy
    21803 (Tgfb1)
   05415 Diabetic cardiomyopathy
    21803 (Tgfb1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    21803 (Tgfb1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    21803 (Tgfb1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mmu03110]
    21803 (Tgfb1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:mmu04052]
    21803 (Tgfb1)
   00536 Glycosaminoglycan binding proteins [BR:mmu00536]
    21803 (Tgfb1)
Chaperones and folding catalysts [BR:mmu03110]
 Intramolecular chaperones
  Others
   21803 (Tgfb1)
Cytokines and neuropeptides [BR:mmu04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   21803 (Tgfb1)
Glycosaminoglycan binding proteins [BR:mmu00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   21803 (Tgfb1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta CBM96 ARID
Other DBs
NCBI-GeneID: 21803
NCBI-ProteinID: NP_035707
MGI: 98725
Ensembl: ENSMUSG00000002603
UniProt: P04202 Q3UNK5
Structure
Position
7:25386406..25404503
AA seq 390 aa
MPPSGLRLLPLLLPLPWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESADPEPEPEADYYAKEVTRVLMVDRNNAI
YEKTKDISHSIYMFFNTSDIREAVPEPPLLSRAELRLQRLKSSVEQHVELYQKYSNNSWR
YLGNRLLTPTDTPEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNKLHVEINGIS
PKRRGDLGTIHDMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccctcggggctgcggctactgccgcttctgctcccactcccgtggcttctagtg
ctgacgcccgggaggccagccgcgggactctccacctgcaagaccatcgacatggagctg
gtgaaacggaagcgcatcgaagccatccgtggccagatcctgtccaaactaaggctcgcc
agtcccccaagccagggggaggtaccgcccggcccgctgcccgaggcggtgctcgctttg
tacaacagcacccgcgaccgggtggcaggcgagagcgccgacccagagccggagcccgaa
gcggactactatgctaaagaggtcacccgcgtgctaatggtggaccgcaacaacgccatc
tatgagaaaaccaaagacatctcacacagtatatatatgttcttcaatacgtcagacatt
cgggaagcagtgcccgaacccccattgctgtcccgtgcagagctgcgcttgcagagatta
aaatcaagtgtggagcaacatgtggaactctaccagaaatatagcaacaattcctggcgt
taccttggtaaccggctgctgacccccactgatacgcctgagtggctgtcttttgacgtc
actggagttgtacggcagtggctgaaccaaggagacggaatacagggctttcgattcagc
gctcactgctcttgtgacagcaaagataacaaactccacgtggaaatcaacgggatcagc
cccaaacgtcggggcgacctgggcaccatccatgacatgaaccggcccttcctgctcctc
atggccacccccctggaaagggcccagcacctgcacagctcacggcaccggagagccctg
gataccaactattgcttcagctccacagagaagaactgctgtgtgcggcagctgtacatt
gactttaggaaggacctgggttggaagtggatccacgagcccaagggctaccatgccaac
ttctgtctgggaccctgcccctatatttggagcctggacacacagtacagcaaggtcctt
gccctctacaaccaacacaacccgggcgcttcggcgtcaccgtgctgcgtgccgcaggct
ttggagccactgcccatcgtctactacgtgggtcgcaagcccaaggtggagcagttgtcc
aacatgattgtgcgctcctgcaagtgcagctga

  All links  
Gene (10)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (18)   
   RefSeq(nuc) (2)   
   GenBank (8)   
   EMBL (8)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (38)   

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