KEGG   Mus musculus (house mouse): 22137
Entry
22137             CDS       T01002                                 
Symbol
Ttk, Esk1, Mps1, PYT, esk
Name
(RefSeq) Ttk protein kinase
  KO
K08866  serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04110  Cell cycle
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    22137 (Ttk)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    22137 (Ttk)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    22137 (Ttk)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.1  dual-specificity kinase
     22137 (Ttk)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  TTK family
   22137 (Ttk)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     22137 (Ttk)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 FTA2 RIO1 PSD13_N Kdo Mad3_BUB1_I Mad3_BUB1_I_2 HAT_PRP39_C Tubulin
Other DBs
NCBI-GeneID: 22137
NCBI-ProteinID: NP_001103735
MGI: 1194921
Ensembl: ENSMUSG00000038379
UniProt: Q8BY97
Position
9:83716704..83754442
AA seq 815 aa
MEAEELIGSSVTIDSIMSKMRDIKNKINEDCTDELSLSKICADHTETVNQIMRVGNTPEN
WLNFLLKLEKNSSPLNDDLLNKLIGRYSQAIEVLPPDKYGQNESFARIQVRLAELKAIQE
PDDARDYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAM
RNLHLQKKQLLPEEDKKSVSASTVLSAQEPFSSSLGNVQNRSISCESRGQAGAARVLYGE
NLPPQDAEVRHQNPFKQTHAAKRSCPFGRVPVNLLNSPDFYVKTDSSAVTQLTTRKGSGP
DRDAILPGSRPRGSDSYELRGLKPIQTIYLKDSLVSNEKSSELMSDLIALKSKTDSSLTK
LEETKPEIAERRPMQWQSTRKPECVFQNPAAFAPLRHVPDVTPKADKESPPISVPKWLDP
KSACETPSSSSLDDYMKCFKTPVVKNDFPPACPSSTPYSQLARLQQQQQQGLSTPLQSLQ
ISGSSSINECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIES
YRNEIAFLNKLQQHSDKIIRLYDYEITEQYIYMVMECGNIDLNSWLKKKKSINPWERKSY
WKNMLEAVHIIHQHGIVHSDLKPANFVIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTV
NYMAPEAIRDMSSSRENSKIRTKVSPRSDVWSLGCILYYMTYGRTPFQHIINQVSKLHAI
INPAHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLTHPYVQIQPHPGSQMARGATD
EMKYVLGQLVGLNSPNSILKTAKVSACTLLPAVLM
NT seq 2448 nt   +upstreamnt  +downstreamnt
atggaggctgaagagttaattggcagcagtgtgacgattgattccatcatgagcaaaatg
agagatattaaaaataagataaatgaagactgtactgatgagctaagcttgtctaaaatc
tgtgccgatcacacggaaactgttaaccaaattatgagggttgggaacaccccagagaac
tggttgaatttcttgctgaaactagagaaaaacagctcacctctaaatgacgatctttta
aataagctgattggtcggtatagtcaagcgattgaagtacttcctccagataaatacggc
cagaatgagagctttgctcgaatacaagtgagacttgctgaactaaaagctattcaagag
cctgatgatgcccgtgactacttccagatggccagggaaaactgcaagaagtttgctttt
gtgcacgtatcttttgcacagtttgaactgtctcaaggcaatcttaaaaaaagtgagcag
cttcttcataaagctgtagagactggggcggtgccgctgcagatgctggagacggccatg
cgtaacttacacctccagaaaaagcagctgcttccggaggaggacaagaagagtgtgtca
gcatcgacagtactaagtgcccaagagccgttctccagctcacttggaaatgtacagaat
cggagcatcagctgtgagtccagaggacaggctggggcagccagggttttatatggagag
aacttgcctccacaagatgccgaagtgaggcatcaaaaccccttcaagcagactcacgca
gctaaacggtcatgcccctttggaagagtcccagtcaatcttctaaacagcccagatttc
tatgtgaagacagatagctcagctgtgacacagttaacaacaagaaaggggtcaggacca
gaccgagacgcgattctgcccggctccagaccacgtggcagtgattcctatgaactgaga
ggtttaaagcccattcaaactatctatttgaaagactctttggtgtccaatgaaaagagt
tctgaacttatgtctgatttaatagccttgaagagtaaaacagattcaagtctaacaaaa
ttggaagaaactaagccagagattgcagaaagaaggcccatgcagtggcagtctaccaga
aagcccgagtgtgtgttccagaaccctgctgcctttgcacccctgcggcacgttccagat
gtcaccccgaaggctgacaaagagtcaccaccaatatcagttcctaaatggcttgatcca
aagtctgcttgtgagacacctagtagcagctccttggatgattacatgaaatgttttaag
actccagttgtaaagaatgactttccacctgcctgtccatcatcaacaccttacagccag
cttgcccgcctccagcagcaacagcagcagggactcagcactcctcttcaaagcttgcag
atttcaggttcttcatcaataaatgaatgcatttcagttaacggaagaatttattccata
ttaaagcagataggcagtggaggttccagtaaggtgtttcaggtattgaatgagaaaaaa
cagataaacgctatcaaatatgtgaacctagaagacgccgatagccaaactattgagagc
taccgcaacgagatagcgtttttgaacaaactacagcaacacagtgataagatcatccgc
ctctatgattatgaaatcaccgagcagtacatctacatggtaatggaatgtggaaacatt
gacctaaatagttggcttaaaaagaaaaaatccatcaatccatgggaacgcaagagctac
tggaaaaacatgttggaggcagtacacataatccatcagcatggtattgttcatagtgat
ctgaagcctgctaactttgtgatagtggatggaatgctaaagctaattgattttgggatt
gcaaaccaaatgcagccagacacaacaagcattgttaaagattctcaggttggcacagtt
aactatatggccccagaagcaatcagagacatgtcttcttcaagagaaaattcgaaaatc
aggaccaaggtaagtcccagaagtgatgtctggtccttggggtgcattttgtactacatg
acttatgggaggacgccatttcagcacatcatcaatcaggtctctaaactgcacgccata
atcaaccctgctcatgagattgaatttcccgagatttcggaaaaagatcttcgagacgtg
ttaaagtgctgtttagtgaggaaccctaaagagaggatatctatccctgagcttctcaca
catccgtatgttcaaattcagccccatccaggcagccaaatggctaggggagccactgat
gaaatgaaatatgtgttgggtcaacttgttggtctgaattctcctaactccatcttgaaa
actgcaaaagtgagtgcatgtacattacttccagctgttttaatgtaa

  All links  
Gene (20)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (31)   
   RefSeq(nuc) (5)   
   GenBank (13)   
   EMBL (13)   
Protein domain (12)   
   Pfam (12)   
All databases (69)   

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