KEGG   Mus musculus (mouse): 22137Help
Entry
22137             CDS       T01002                                 

Gene name
Ttk, AL022661, Esk1, Mps1, PYT, esk
Definition
(RefSeq) Ttk protein kinase
  KO
K08866  serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04110  Cell cycle
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    22137 (Ttk)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.1  dual-specificity kinase
     22137 (Ttk)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  TTK family
   22137 (Ttk)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     22137 (Ttk)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kinase-like RIO1 FTA2 Kdo Mad3_BUB1_I Mad3_BUB1_I_2 Tubulin
Motif
Other DBs
NCBI-GeneID: 22137
NCBI-ProteinID: NP_001103735
MGI: 1194921
Ensembl: ENSMUSG00000038379
Vega: OTTMUSG00000044947
UniProt: Q8BY97
Position
9; 9 E2
AA seq 815 aa AA seqDB search
MEAEELIGSSVTIDSIMSKMRDIKNKINEDCTDELSLSKICADHTETVNQIMRVGNTPEN
WLNFLLKLEKNSSPLNDDLLNKLIGRYSQAIEVLPPDKYGQNESFARIQVRLAELKAIQE
PDDARDYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAM
RNLHLQKKQLLPEEDKKSVSASTVLSAQEPFSSSLGNVQNRSISCESRGQAGAARVLYGE
NLPPQDAEVRHQNPFKQTHAAKRSCPFGRVPVNLLNSPDFYVKTDSSAVTQLTTRKGSGP
DRDAILPGSRPRGSDSYELRGLKPIQTIYLKDSLVSNEKSSELMSDLIALKSKTDSSLTK
LEETKPEIAERRPMQWQSTRKPECVFQNPAAFAPLRHVPDVTPKADKESPPISVPKWLDP
KSACETPSSSSLDDYMKCFKTPVVKNDFPPACPSSTPYSQLARLQQQQQQGLSTPLQSLQ
ISGSSSINECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIES
YRNEIAFLNKLQQHSDKIIRLYDYEITEQYIYMVMECGNIDLNSWLKKKKSINPWERKSY
WKNMLEAVHIIHQHGIVHSDLKPANFVIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTV
NYMAPEAIRDMSSSRENSKIRTKVSPRSDVWSLGCILYYMTYGRTPFQHIINQVSKLHAI
INPAHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLTHPYVQIQPHPGSQMARGATD
EMKYVLGQLVGLNSPNSILKTAKVSACTLLPAVLM
NT seq 2448 nt NT seq  +upstreamnt  +downstreamnt
atggaggctgaagagttaattggcagcagtgtgacgattgattccatcatgagcaaaatg
agagatattaaaaataagataaatgaagactgtactgatgagctaagcttgtctaaaatc
tgtgccgatcacacggaaactgttaaccaaattatgagggttgggaacaccccagagaac
tggttgaatttcttgctgaaactagagaaaaacagctcacctctaaatgacgatctttta
aataagctgattggtcggtatagtcaagcgattgaagtacttcctccagataaatacggc
cagaatgagagctttgctcgaatacaagtgagacttgctgaactaaaagctattcaagag
cctgatgatgcccgtgactacttccagatggccagggaaaactgcaagaagtttgctttt
gtgcacgtatcttttgcacagtttgaactgtctcaaggcaatcttaaaaaaagtgagcag
cttcttcataaagctgtagagactggggcggtgccgctgcagatgctggagacggccatg
cgtaacttacacctccagaaaaagcagctgcttccggaggaggacaagaagagtgtgtca
gcatcgacagtactaagtgcccaagagccgttctccagctcacttggaaatgtacagaat
cggagcatcagctgtgagtccagaggacaggctggggcagccagggttttatatggagag
aacttgcctccacaagatgccgaagtgaggcatcaaaaccccttcaagcagactcacgca
gctaaacggtcatgcccctttggaagagtcccagtcaatcttctaaacagcccagatttc
tatgtgaagacagatagctcagctgtgacacagttaacaacaagaaaggggtcaggacca
gaccgagacgcgattctgcccggctccagaccacgtggcagtgattcctatgaactgaga
ggtttaaagcccattcaaactatctatttgaaagactctttggtgtccaatgaaaagagt
tctgaacttatgtctgatttaatagccttgaagagtaaaacagattcaagtctaacaaaa
ttggaagaaactaagccagagattgcagaaagaaggcccatgcagtggcagtctaccaga
aagcccgagtgtgtgttccagaaccctgctgcctttgcacccctgcggcacgttccagat
gtcaccccgaaggctgacaaagagtcaccaccaatatcagttcctaaatggcttgatcca
aagtctgcttgtgagacacctagtagcagctccttggatgattacatgaaatgttttaag
actccagttgtaaagaatgactttccacctgcctgtccatcatcaacaccttacagccag
cttgcccgcctccagcagcaacagcagcagggactcagcactcctcttcaaagcttgcag
atttcaggttcttcatcaataaatgaatgcatttcagttaacggaagaatttattccata
ttaaagcagataggcagtggaggttccagtaaggtgtttcaggtattgaatgagaaaaaa
cagataaacgctatcaaatatgtgaacctagaagacgccgatagccaaactattgagagc
taccgcaacgagatagcgtttttgaacaaactacagcaacacagtgataagatcatccgc
ctctatgattatgaaatcaccgagcagtacatctacatggtaatggaatgtggaaacatt
gacctaaatagttggcttaaaaagaaaaaatccatcaatccatgggaacgcaagagctac
tggaaaaacatgttggaggcagtacacataatccatcagcatggtattgttcatagtgat
ctgaagcctgctaactttgtgatagtggatggaatgctaaagctaattgattttgggatt
gcaaaccaaatgcagccagacacaacaagcattgttaaagattctcaggttggcacagtt
aactatatggccccagaagcaatcagagacatgtcttcttcaagagaaaattcgaaaatc
aggaccaaggtaagtcccagaagtgatgtctggtccttggggtgcattttgtactacatg
acttatgggaggacgccatttcagcacatcatcaatcaggtctctaaactgcacgccata
atcaaccctgctcatgagattgaatttcccgagatttcggaaaaagatcttcgagacgtg
ttaaagtgctgtttagtgaggaaccctaaagagaggatatctatccctgagcttctcaca
catccgtatgttcaaattcagccccatccaggcagccaaatggctaggggagccactgat
gaaatgaaatatgtgttgggtcaacttgttggtctgaattctcctaactccatcttgaaa
actgcaaaagtgagtgcatgtacattacttccagctgttttaatgtaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (32)   
   RefSeq(nuc) (6)   
   GenBank (13)   
   EMBL (13)   
Protein domain (9)   
   Pfam (9)   
All databases (79)   

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