KEGG   Mus musculus (house mouse): 22145
Entry
22145             CDS       T01002                                 
Symbol
Tuba4a, M[a]4, Tuba4
Name
(RefSeq) tubulin, alpha 4A
  KO
K07374  tubulin alpha
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04145  Phagosome
mmu04210  Apoptosis
mmu04530  Tight junction
mmu04540  Gap junction
mmu04814  Motor proteins
mmu05010  Alzheimer disease
mmu05012  Parkinson disease
mmu05014  Amyotrophic lateral sclerosis
mmu05016  Huntington disease
mmu05020  Prion disease
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    22145 (Tuba4a)
  09143 Cell growth and death
   04210 Apoptosis
    22145 (Tuba4a)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    22145 (Tuba4a)
   04540 Gap junction
    22145 (Tuba4a)
  09142 Cell motility
   04814 Motor proteins
    22145 (Tuba4a)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    22145 (Tuba4a)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    22145 (Tuba4a)
   05012 Parkinson disease
    22145 (Tuba4a)
   05014 Amyotrophic lateral sclerosis
    22145 (Tuba4a)
   05016 Huntington disease
    22145 (Tuba4a)
   05020 Prion disease
    22145 (Tuba4a)
   05022 Pathways of neurodegeneration - multiple diseases
    22145 (Tuba4a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    22145 (Tuba4a)
   03036 Chromosome and associated proteins [BR:mmu03036]
    22145 (Tuba4a)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:mmu04812]
    22145 (Tuba4a)
   04147 Exosome [BR:mmu04147]
    22145 (Tuba4a)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     22145 (Tuba4a)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     22145 (Tuba4a)
Cytoskeleton proteins [BR:mmu04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    22145 (Tuba4a)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   22145 (Tuba4a)
  Exosomal proteins of other body fluids (saliva and urine)
   22145 (Tuba4a)
  Exosomal proteins of colorectal cancer cells
   22145 (Tuba4a)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3
Other DBs
NCBI-GeneID: 22145
NCBI-ProteinID: NP_033473
MGI: 1095410
Ensembl: ENSMUSG00000026202
UniProt: P68368
Structure
Position
1:complement(75190867..75197905)
AA seq 448 aa
MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK
HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD
RIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGIDSYEDEDEGEE
NT seq 1347 nt   +upstreamnt  +downstreamnt
atgcgcgagtgcatttcagtccatgtggggcaggcaggtgtccagatgggcaatgcctgc
tgggagctctactgtctggaacatgggattcagcctgatgggcagatgcccagcgataag
accattggtggaggggacgactccttcaccaccttcttctgtgaaactggagctggaaaa
catgtgcctcgggcagtctttgtggacctggagcctactgtaatcgatgagatccgaaat
ggcccataccgtcagctcttccacccagagcagcttatcactgggaaagaagatgcagcc
aacaactatgcccgtggtcattacaccattggcaaggagatcatcgacccagtgctggac
cggatccgcaagctgtctgatcagtgcacaggacttcagggcttcctagtattccacagc
tttggagggggcaccggctctggcttcacctctctgctgatggagcggctttctgttgac
tatggcaaaaagtccaagctggaattctccatctacccagccccccaagtgtccacggct
gtagtggagccctacaactccatcctgaccacccataccaccctggaacactcagactgt
gccttcatggtggacaacgaagccatttatgatatctgccgccgtaacctagatattgag
cgtccaacctataccaacctcaaccgcctcatcagccaaattgtctcctccatcacagct
tccttgcgctttgatggggccctcaatgtggacctgacagagttccagaccaacctggtg
ccctaccctcgcatccacttccccttggctacctatgcaccagtcatttctgcagagaag
gcctaccatgagcagctgtcagtggcagagatcaccaatgcctgttttgagcctgccaac
cagatggtgaaatgtgaccctcggcacggcaagtacatggcctgctgcctgctgtaccgt
ggagatgtggtgcccaaagatgtgaatgctgccatagctgccatcaagacgaagcgcagc
atccagtttgtggactggtgccccacaggcttcaaggttggcatcaactaccaaccaccc
actgtggtgcctgggggtgacctggccaaggtgcagcgtgctgtgtgcatgctgagcaac
acaaccgccattgctgaagcctgggcccgtctggaccacaagtttgacttgatgtatgcc
aagagggcttttgtacactggtatgtgggtgagggaatggaggagggggagttctctgag
gctcgagaggatatggctgccctggaaaaagattatgaggaagtaggcatcgactcctat
gaggacgaggatgagggagaagagtag

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (197)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (190)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (21)   
   RefSeq(nuc) (7)   
   GenBank (7)   
   EMBL (7)   
3D Structure (2)   
   PDB (2)   
Protein domain (3)   
   Pfam (3)   
All databases (250)   

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