KEGG   Mus musculus (house mouse): 230073
Entry
230073            CDS       T01002                                 
Symbol
Rigi, 6430573D20Rik, C330021E21, Ddx58, RIG-I, RLR-1
Name
(RefSeq) antiviral innate immune response receptor RIG-I
  KO
K12646  ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04064  NF-kappa B signaling pathway
mmu04622  RIG-I-like receptor signaling pathway
mmu04623  Cytosolic DNA-sensing pathway
mmu05160  Hepatitis C
mmu05161  Hepatitis B
mmu05162  Measles
mmu05164  Influenza A
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    230073 (Rigi)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    230073 (Rigi)
   04623 Cytosolic DNA-sensing pathway
    230073 (Rigi)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    230073 (Rigi)
   05160 Hepatitis C
    230073 (Rigi)
   05171 Coronavirus disease - COVID-19
    230073 (Rigi)
   05164 Influenza A
    230073 (Rigi)
   05162 Measles
    230073 (Rigi)
   05168 Herpes simplex virus 1 infection
    230073 (Rigi)
   05169 Epstein-Barr virus infection
    230073 (Rigi)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:mmu04054]
    230073 (Rigi)
Enzymes [BR:mmu01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.6  RNA 3'-5' helicase
     230073 (Rigi)
Pattern recognition receptors [BR:mmu04054]
 Cytoplasmic pattern recognition receptors
  RIG-I-like receptors
   230073 (Rigi)
SSDB
Motif
Pfam: CARD_2 RIG-I_C RIG-I_C-RD DEAD ResIII Helicase_C AAA_25
Other DBs
NCBI-GeneID: 230073
NCBI-ProteinID: NP_766277
MGI: 2442858
Ensembl: ENSMUSG00000040296
UniProt: Q6Q899 A1L0V6
Structure
Position
4:complement(40203775..40239843)
AA seq 926 aa
MTAEQRQNLQAFRDYIKKILDPTYILSYMSSWLEDEEVQYIQAEKNNKGPMEAASLFLQY
LLKLQSEGWFQAFLDALYHAGYCGLCEAIESWDFQKIEKLEEHRLLLRRLEPEFKATVDP
NDILSELSECLINQECEEIRQIRDTKGRMAGAEKMAECLIRSDKENWPKVLQLALEKDNS
KFSELWIVDKGFKRAESKADEDDGAEASSIQIFIQEEPECQNLSQNPGPPSEASSNNLHS
PLKPRNYQLELALPAKKGKNTIICAPTGCGKTFVSLLICEHHLKKFPCGQKGKVVFFANQ
IPVYEQQATVFSRYFERLGYNIASISGATSDSVSVQHIIEDNDIIILTPQILVNNLNNGA
IPSLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGESRDPLPQVVGLTASVGVGDAKT
AEEAMQHICKLCAALDASVIATVRDNVAELEQVVYKPQKISRKVASRTSNTFKCIISQLM
KETEKLAKDVSEELGKLFQIQNREFGTQKYEQWIVGVHKACSVFQMADKEEESRVCKALF
LYTSHLRKYNDALIISEDAQMTDALNYLKAFFHDVREAAFDETERELTRRFEEKLEELEK
VSRDPSNENPKLRDLYLVLQEEYHLKPETKTILFVKTRALVDALKKWIEENPALSFLKPG
ILTGRGRTNRATGMTLPAQKCVLEAFRASGDNNILIATSVADEGIDIAECNLVILYEYVG
NVIKMIQTRGRGRARDSKCFLLTSSADVIEKEKANMIKEKIMNESILRLQTWDEMKFGKT
VHRIQVNEKLLRDSQHKPQPVPDKENKKLLCGKCKNFACYTADIRVVETSHYTVLGDAFK
ERFVCKPHPKPKIYDNFEKKAKIFCAKQNCSHDWGIFVRYKTFEIPVIKIESFVVEDIVS
GVQNRHSKWKDFHFERIQFDPAEMSV
NT seq 2781 nt   +upstreamnt  +downstreamnt
atgacagcggagcagcggcagaatctgcaagcattcagagactatatcaagaagattctg
gaccccacctacatcctcagctacatgagttcctggctcgaggatgaggaggtgcagtac
attcaggctgagaagaacaacaagggcccaatggaagctgcctcactcttcctccagtac
ctgttgaagctgcagtcagagggctggttccaggcctttttggatgccctgtaccatgca
ggttactgtggactttgtgaagccatcgaaagttgggactttcaaaaaattgaaaagtta
gaggaacacagattacttttaagacgtttagaaccagaatttaaggccacagttgatcca
aatgatatcctttctgaactatccgaatgtttgattaatcaggaatgtgaagaaatcaga
cagatccgagacactaaagggagaatggcaggtgcggagaagatggccgaatgtcttatc
agatccgacaaggaaaactggccaaaggtcttgcaacttgctttggagaaagacaacagc
aagtttagtgaattgtggattgttgataaaggtttcaaaagggctgaaagcaaggctgat
gaggatgatggagcggaggcgtccagcatccagattttcattcaggaagagccagagtgt
cagaatctcagtcagaatcccgggcctccttcagaagcgtcttctaataatttacacagc
ccattgaaaccaagaaattaccaactggagcttgccctgcctgccaagaaagggaaaaat
acaataatatgtgcccctactggttgtggaaaaacctttgtgtcgcttcttatatgtgaa
caccatcttaaaaaattcccatgtggacaaaaagggaaagtggtcttcttcgctaaccaa
attcctgtctatgagcagcaggcaactgtgttctcacgatattttgaaagacttgggtac
aacattgcgagcatttctggggcaacatctgatagcgtctcagtgcagcacatcattgaa
gacaatgatatcatcatcctgacaccccagattcttgtgaacaatctcaacaacggagcc
atcccctcgttgtctgtcttcactctgatgatatttgatgagtgtcataacactagcaaa
aaccacccatacaatcagatcatgttcagatacctagaccacaaacttggagagtcacgg
gacccactgcctcaggtcgttgggctgactgcctccgtcggcgttggagatgctaagacc
gcggaggaagccatgcaacatatctgtaaactctgtgccgccctggatgcctccgtgatt
gccacagtcagagacaacgttgcagaactggaacaggtcgtttataagccccagaaaatt
tccaggaaagtggcatcccggacttcgaacacgtttaaatgcatcatctctcagctgatg
aaggagacagagaagctagccaaggatgtctccgaggaacttggaaagctttttcaaatt
caaaacagagaattcggcacccagaaatatgaacagtggattgtcggcgtccacaaagcg
tgctcagtgtttcagatggcagacaaagaggaggagagccgggtctgcaaagcgctcttc
ctgtacacatcacatttgcggaaatacaacgatgcactcatcatcagtgaggatgcacag
atgacagacgctctaaattacctcaaagccttcttccacgatgtccgagaagcagcattc
gatgagaccgagcgagagcttactcggaggtttgaagaaaaactagaggaattagaaaaa
gtttccagggatcccagcaatgagaatcctaaactaagagacctctacttggtcttacaa
gaagagtaccacttaaagccagagaccaagaccattctcttcgtgaagaccagagcactc
gtggatgctctgaagaaatggattgaagaaaatcctgcactaagctttctaaagcctggc
atactgactgggcgtggcagaacaaaccgggcaacaggaatgacgctcccggcacagaag
tgtgtgctggaggcattcagagccagcggagataacaatattctgattgctacctcggtc
gctgatgaaggcattgacattgctgagtgcaatctcgtcattctctatgagtacgtgggc
aacgtcatcaagatgatccaaaccagaggccgaggaagagcacgagatagcaagtgcttc
ctcctgaccagcagcgctgacgtgattgaaaaagaaaaggcgaacatgatcaaggaaaaa
ataatgaatgaatccatcttaagactgcagacatgggatgaaatgaaatttggaaagacg
gttcaccgcatacaggtgaatgaaaaactcctcagagacagtcagcacaaaccacaacct
gttcctgacaaagaaaacaagaaactgctgtgtggaaagtgcaagaattttgcgtgctac
acagctgacattcgagtggttgagacgtcccactacactgtccttggagacgcttttaag
gagcgctttgtgtgtaagccacaccctaaaccaaagatctatgacaattttgagaagaaa
gcaaagatattctgcgccaaacagaactgtagccacgactggggaatttttgtgagatac
aagacgttcgagattccagtcataaaaattgaaagtttcgtcgtggaagatattgtgagc
ggagttcagaaccggcactcaaagtggaaggactttcattttgaaaggatacagttcgat
cctgcagaaatgtccgtatga

  All links  
Gene (23)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (26)   
   RefSeq(nuc) (2)   
   GenBank (12)   
   EMBL (12)   
3D Structure (2)   
   PDB (2)   
Protein domain (7)   
   Pfam (7)   
All databases (63)   

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