KEGG   Mus musculus (house mouse): 232341
Entry
232341            CDS       T01002                                 
Symbol
Wnk1, 6430573H23Rik, EG406236, Hsn2, Prkwnk1, mKIAA0344
Name
(RefSeq) WNK lysine deficient protein kinase 1
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    232341 (Wnk1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    232341 (Wnk1)
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    232341 (Wnk1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     232341 (Wnk1)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  Wnk family
   232341 (Wnk1)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     232341 (Wnk1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C Pkinase_fungal
Other DBs
NCBI-GeneID: 232341
NCBI-ProteinID: NP_941992
MGI: 2442092
Ensembl: ENSMUSG00000045962
UniProt: P83741
Position
6:complement(119900930..120015659)
AA seq 2377 aa
MSDGAAEKQSGTPGFLTPPAPVPKNGSSSDSSVGEKLGATVADSGVGRTEEYRRRRHTMD
KDSRGAAATTTPTEHRFFRRSVICDSNATALELPGLPLSIPQPSVPAVVPQSAPPEPHRE
ETLTATVASQVSQQPSAAASPGEQAVVGSATTTVPSSTSKDRPVSQPSLVGSKEEPPPSR
SGSGSGGASAKEAQEDRSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLD
TETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLV
TELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP
TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEY
PYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQ
EETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM
VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKRKQEESSFKQQNEQQASVS
QAGIQQLSAASTGIPTAPATSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTIDSGQ
GSSVFTESRVSSQQTVSYGSQHEQAHSTGTAPGHTVSSIQAQSQPHGVYPPSSMAQGQNQ
GQPSSSLAGVLSSQPIQHPQQQGIQPTVPSQQAVQYSLPQAASSSEGTTAQPVSQPQVSA
GTQLPVSQTVATVQGEPHIPVSTQPSVVPVHSGAHFLPMGQPIPTSLLPQYPVSQIPIST
PHVSTAQTGFSSVPITMAAGINQPLLTLASSATASSIPGGSPVVPNQLPTLLQPVNQLQS
QVHPQLLQPTTVQSIGIPANLGQAAEGPLPSGDVLYQGFPSRLPPQYPGDSNIAPSSNVA
SVCIHSTVLAPPSMPTEALATQGYFPTVVQPYVESTPLVPMGSVGGQVQVSQPAVSLTQQ
PPTTSSQQAVLESTQGVSQAAPPEQTPITQSQPTQPVPLVTSADSAHSDVASGMSDGNEN
APSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMV
TFKFDLDGDNPEEIATIMVNNDFILAIERESFVAQVREIIEKADEMLSEDVSVEPEGDQG
LESLQGKDDYGFPGSQKLEGEFKQPIAVSSMPQQIGVPTSSLTQVVHSAGRRFIVSPVPE
SRLRESKVFTSDISDPVVASTSQAPGMNLSHSASSLSLQQAFSELKHGQMTEGPNTAPPN
FNHMAGPTFSPFLASIAGVQTVAASTPSVSVPITSSPLNDISTSVMQSETALPTEKGIVG
VTTTSTGVVASGGLTTMSVSESPTSSSAVSSSTVPAVVTVSTPSQPVQASTSGSIASSTG
SFPPGTFSTTTATTMGSVVAPDAKPPTVLLQQVASNTAGVAIVTSVSTTTPFPGMASQPS
LPLSSSTSAPTLAETMVVSAHSLDKASHSSTAGLGLSFCAPSSSSSSGTAVSTSVSQPGM
VHPLVISSAVVSTPGLPQPVVPTSTPLLPQVPNIPPLVQPVVNVPAVQQTLIHSQPQPAL
LPNQPHTHCPEMDADTQSKAPGIDDIKTLEEKLRSLFSEHSSSGTQHASVSLETPLVVET
TVTPGITTTAVAPSKLMTSTTSTCLPPTSLPLGAAGMPVMPVGTPGQVSTPGTHASAPVG
TATGVKPGTTPPKPTKTVVPPVGTELSAGTVPCEQLPPFPGPSLIQSQQPLEDLDAQLRR
TLSPETITVAPAVGPLSTMSSTTVTEAGTRLQKDGTEGHVTATSSGAGVVKMGRFQVSVT
MDDAQKERKNRSEDTKSVHFESSTSESSVLSSSSPESTLVKPEPNGISISGISLDVPDST
HKAPTPEAKSDAGQPTKVGRFQVTTTANKVGRFSVSRTEDKVTELKKEGPVTSPPFRDSE
QTVIPAVIPKKEKPELAEPSHLNGPSSDLEAAFLSRGTEDGSGSPHSPPHLCSKSLPVQN
LSQSLSNSFNSSYMSSDNESDIEDEDLRLELRRLREKHLKEIQDLQSRQKHEIESLYTKL
GKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSGTSVLHPQQ
TLHPAGNTPETGHNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGGT
VSSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPGMARKF
SAPGQLCVPMTSNLGGSTPISAASATSLGHFTKSMCPPQQYGFPPAPFGTQWSGTGGPAP
QPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT
NT seq 7134 nt   +upstreamnt  +downstreamnt
atgtctgacggtgccgccgagaagcaaagcggcactccgggcttccttacgcctccggcg
cccgtccccaagaatggctcaagctccgattcttccgtgggcgagaaactgggggctacg
gtcgccgactcgggagttggcaggacggaggaatatcggcgccgccggcacactatggac
aaggacagtcgtggggcggccgccaccaccacccccacggagcaccgattcttccgccga
agcgtcatctgcgactccaatgccaccgcgttggagctgccgggcctccctctctctatc
ccgcaacctagtgtacctgcagtggtgccccagagtgctccacccgaacctcacagagag
gaaactttgaccgccaccgttgcttcccaggtgtctcagcaaccctcggctgctgcctcc
cctggggaacaagccgttgtaggctcggccaccacgaccgtccccagcagtaccagcaaa
gaccgcccggtgtcccagcccagcctcgtggggagcaaagaggagccaccgccgtccaga
agtggaagtggcagtggtggcgccagcgccaaagaggcgcaggaggataggagccagcaa
caggatgatatcgaagagctggagaccaaggcagtgggaatgtccaatgacggtcgcttt
ctcaaatttgacatcgaaatcggcagaggctcctttaagacagtctacaaaggtctggac
accgaaaccactgtggaagtcgcctggtgtgaattgcaggatcgaaagttaacaaaatct
gaaaggcagagattcaaagaagaggctgaaatgttaaagggtcttcaacatcccaacatt
gttcgattctatgattcctgggaatccacagtaaaagggaaaaaatgcattgttttagtg
actgaactaatgacatctggaacacttaagacgtacttaaaaaggtttaaagtgatgaaa
atcaaagttttaagaagctggtgtcggcaaatccttaaagggcttcagtttctccacaca
cgaactccaccaattattcaccgggatcttaaatgtgacaacatctttatcactggtcct
actggctcagtcaagatcggagaccttggtctggcaactctaaagcgggcttcttttgcc
aagagtgtgataggtaccccagagtttatggctcctgagatgtatgaggagaaatatgat
gaatccgttgatgtttatgcttttgggatgtgcatgcttgagatggctacatctgaatat
ccatactcagaatgccaaaatgctgcgcagatctaccgtcgagtgaccagtggagtgaag
ccagccagttttgacaaagtagcaattcctgaagtaaaagaaattattgaaggatgtatc
cgacaaaacaaagatgaaagatattccatcaaagaccttttgaaccatgcctttttccag
gaggaaacaggggtacgggtagaattagcagaagaagatgatggagaaaagatagctatt
aaattatggctgcgtattgaagatattaagaaattaaagggaaaatacaaagacaatgaa
gctattgagttttcctttgacttggagagggatgtaccagaagatgttgctcaagaaatg
gttgagtctggttatgtctgtgaaggtgatcacaagaccatggctaaagctatcaaagat
agggtgtccttaattaagagaaaacgagagcagcggcagttggttcgagaagagcaagaa
aaaagaaaacaagaagagagcagtttcaaacagcagaatgaacaacaagcaagcgtttcc
caggcaggaatccagcagctctctgctgctagcactggcatacccactgctcctgccacc
tctgcttcagtttctacacaggtagaacctgaagaacctgaggcagatcaacatcaacag
ctgcaatatcagcaacctagtatatctgtgttgtctgatggaaccattgatagtggtcaa
ggatcatccgtattcacagaatccagagtgagcagccaacagactgtttcctatggttcc
caacatgagcaggcacattctactggcacagcaccaggacatacagtttctagtatccaa
gcacaatctcagccccatggggtgtatccaccctcaagtatggcacaggggcagaaccag
ggccagccatcaagtagtttggctggggttctatcttcacaacctatccaacatcctcag
cagcagggaatacagccaactgttccttctcaacaggcagtacagtattcacttccacaa
gcagcatcttccagtgaaggtactactgcacagccagtgagtcagcctcaagtgtcagct
ggaacacagcttccagtttcccagacagtagcaactgtccaaggtgaacctcacatccca
gtttcaacacaaccctcagttgttccagtccactctggtgctcatttccttcctatggga
cagccaatccctacttctttactcccacagtatcctgtctctcaaattcccatatcgact
cctcatgtgtccacggcgcagacaggtttctcatccgttcctataacaatggctgctggc
attaaccagcctctgctcaccttggcttcatctgctacagcatcttcaatcccaggggga
tcacctgtagttcctaatcagcttccaactcttctgcagcctgtgaatcagctgcagagt
caggttcacccacagcttctacagccaacaacagttcagtccataggaataccagctaac
cttggacaagctgctgagggtccacttccctctggagatgttttgtaccagggcttccca
tctcgactgccaccacaatacccaggagattcaaatattgctccctcttccaacgtggct
tctgtttgcatccattctacagtcctagcccctccttctatgccgacagaagcattggcc
acccaaggttactttcctacagtagtgcagccttatgtggaatcaactcctttggttcct
atgggcagtgtaggaggccaggttcaagtgtcccaaccagcagtgagtttaacgcaacaa
cccccaactacatcctcccagcaagcagttctggagagtactcagggagtctctcaggct
gctcctccagaacaaactccaataacacagtcacaacctactcagcctgttccattggtt
acctctgcagacagtgcacattcagacgttgcttctggtatgagtgatggcaatgagaat
gctccatcatccagcgggaggcatgaagggaggacaacaaaacggcattatagaaaatcc
gtaagaagtcgctctcggcatgaaaagacttctcgcccaaaactgaggattttaaatgtt
tcaaataaaggagaccgagtagtagaatgtcaattagagactcataatcggaagatggtt
acatttaaatttgacctagatggtgacaaccctgaagagatagcaacaattatggtgaac
aatgactttattctagcaatagagagagagtcttttgtggctcaagtgcgggaaattatt
gaaaaggctgatgaaatgttaagtgaggatgtcagtgtggagcctgagggtgaccaggga
ttggagagtctgcaaggaaaggatgactatggcttcccaggttctcagaaattagaagga
gagttcaagcaaccaattgctgtatcttccatgccacaacaaataggtgttcctaccagt
tctttaacgcaagttgttcattctgctggaagacggtttatagtgagtcctgtacctgaa
agtaggttacgagaatcaaaagttttcaccagtgacatatcagatccagttgtggcctct
acatctcaggcccctggaatgaacttatctcactctgcttcatccctcagtctccagcag
gctttttctgaactgaaacatggtcagatgactgaaggacccaatacagcacctccaaat
tttaatcacatggcgggaccaacattttctccctttttggctagcattgctggtgtccaa
actgtagcagcatccacaccgtcagtatcagtccctataacaagcagtcctcttaatgac
atttccacatcagtgatgcagtctgagactgcactgcccactgaaaaaggcatcgtggga
gttaccactaccagcacaggtgtggtagcttcaggtggtctcaccacaatgtctgtgtct
gagtcaccaacatcttccagtgcggtttcaagttctacagtacctgcagttgtcactgtg
tccacaccatcccagccagttcaggcttccacatctgggagcattgcttcaagtacaggc
agttttcctcctggaacattttctacaactacagctactacaatgggtagtgtggtggcc
ccagatgctaagcctccaactgtattattgcaacaggtagcaagcaatactgctggggtt
gccatagtgacatcagtctctaccaccactccattcccaggcatggcttcacagccatcc
cttccacttagtagcagcacctctgctcctactctagctgaaacaatggtggttagtgca
cactcactagacaaggcatctcacagtagtacagcaggattgggtttgtccttttgtgcg
ccatcctcttcctcctcctctggaacagctgtgtctacttctgtttctcagcctggtatg
gttcatcctttggtcatctcatcagctgtagtttctacacctggcctcccccaaccagta
gtacctacttctacacctttattaccccaagtacctaatatcccacccttggtacaacct
gttgttaatgtgcctgctgtacagcaaacactcattcacagtcagcctcaaccagctctg
cttcccaaccagcctcacacacactgtcctgaaatggatgctgatacccaatccaaagct
cctgggattgatgatataaagactctggaggaaaagctgagatctctctttagtgaacac
agctcatctggaactcagcatgcttctgtctccctagagacacctttagtagtagagacg
actgtcacaccgggcatcactaccactgctgtagcaccaagtaaactcatgacttccact
acaagtacttgcttaccaccaaccagtttaccattaggagcagctggcatgccagttatg
ccagtaggcacacctgggcaggtttctaccccaggcacacacgcttcagccccagtcggc
actgcaacaggagtaaaacctggaacaactcccccaaagccaactaagactgtggtgcca
ccagtgggtactgaactttcagccggtactgtaccctgtgagcagctgccaccttttcct
ggaccttctctaattcagtcccagcaaccactagaagatcttgatgctcagttgagaaga
acacttagtccagagactattacagtggcacctgcagttggtcctttgtctacgatgtct
tcaacaacagttacagaagcagggactcggcttcaaaaggatggcacagaaggtcatgtc
acagcaactagttcaggagctggtgttgttaagatggggcgatttcaggtttcagttaca
atggatgatgcccagaaagaacgtaaaaataggtcagaagatacaaagtcggttcatttt
gaatctagcacatcagagtcatcagttctttcaagtagtagtccagagagtaccctggta
aagccagagcctaatggaattagtatttctggcatctccttagatgtcccagacagcacc
cacaaagcacctaccccagaagcaaagtcagatgcaggacagcctaccaaggtgggacgt
tttcaggtgacaactacagccaacaaagtgggtcgtttctctgtttcaagaactgaggac
aaggtcacagagctcaaaaaagagggaccagtgacctctcctcctttcagagattcagaa
caaactgttattcctgctgtgataccaaagaaggagaagcctgagctggcagaaccttcc
catttgaatgggccatcttcagacctggaggctgcctttctaagtaggggtacagaggat
ggctcaggtagtccacactctccccctcacctgtgttcaaagagccttcccgtccagaat
ctaagtcaaagccttagtaattcattcaactcctcatacatgagtagtgacaatgagtcc
gacattgaagatgaagacttaaggttagaactacgacgactacgagaaaaacatcttaaa
gagattcaggacctgcagagtcgccagaagcatgaaattgaatctttgtatactaaactg
ggcaaggttccccctgctgtcattattcccccagctgctcctctgtcggggagaagaagg
agacccactaaaagcaaaggcagcaagtctagtcgcagcagctcattgggcaataaaagc
ccacagctttcaggcaacctgtctggtcagagtggaacttcagtcttacacccccaacag
accctccatcccgcaggaaacacccccgagactgggcacaaccagctgttacagcctctt
aagccatctccctccagtgacaacctctattcagcctttaccagtgatggtgccatttca
gtaccaagcctttctgctccaggtcaagggaccagcagcacaaataccgttggaggaaca
gtgagtagccaggctgcccaggctcagcctcctgctatgacttccagtaggaagggcaca
ttcacagatgacctgcacaagttagtagacaactgggcccgagatgccatgaatctttca
ggcaggagaggcagcaaaggacacatgaattatgagggccctggaatggcaaggaagttc
tctgctcctgggcagctgtgtgttcccatgacctcaaacctgggtggctctacccccatc
tctgcagcatctgctacctctctaggtcacttcaccaaatccatgtgtcccccacagcag
tatggttttccacctgccccatttggcactcagtggagtggaacaggtggtccagcaccg
cagccacttggccagttccaacctgtaggaacagcatccttgcaaaatttcaacatcagc
aatttgcagaagtccatcagcaaccccccaggttccaatctacggaccacctag

  All links  
Gene (49)   
   RefGene (40)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (37)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (35)   
DNA sequence (80)   
   RefSeq(nuc) (36)   
   GenBank (22)   
   EMBL (22)   
Protein domain (5)   
   Pfam (5)   
All databases (171)   

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