KEGG   Mus musculus (house mouse): 232975
Entry
232975            CDS       T01002                                 
Symbol
Atp1a3, Atpa-2
Name
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-3 isoform 2
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04022  cGMP-PKG signaling pathway
mmu04024  cAMP signaling pathway
mmu04260  Cardiac muscle contraction
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04820  Cytoskeleton in muscle cells
mmu04911  Insulin secretion
mmu04918  Thyroid hormone synthesis
mmu04919  Thyroid hormone signaling pathway
mmu04925  Aldosterone synthesis and secretion
mmu04960  Aldosterone-regulated sodium reabsorption
mmu04961  Endocrine and other factor-regulated calcium reabsorption
mmu04964  Proximal tubule bicarbonate reclamation
mmu04970  Salivary secretion
mmu04971  Gastric acid secretion
mmu04972  Pancreatic secretion
mmu04973  Carbohydrate digestion and absorption
mmu04974  Protein digestion and absorption
mmu04976  Bile secretion
mmu04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    232975 (Atp1a3)
   04022 cGMP-PKG signaling pathway
    232975 (Atp1a3)
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    232975 (Atp1a3)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    232975 (Atp1a3)
   04918 Thyroid hormone synthesis
    232975 (Atp1a3)
   04919 Thyroid hormone signaling pathway
    232975 (Atp1a3)
   04925 Aldosterone synthesis and secretion
    232975 (Atp1a3)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    232975 (Atp1a3)
   04261 Adrenergic signaling in cardiomyocytes
    232975 (Atp1a3)
  09154 Digestive system
   04970 Salivary secretion
    232975 (Atp1a3)
   04971 Gastric acid secretion
    232975 (Atp1a3)
   04972 Pancreatic secretion
    232975 (Atp1a3)
   04976 Bile secretion
    232975 (Atp1a3)
   04973 Carbohydrate digestion and absorption
    232975 (Atp1a3)
   04974 Protein digestion and absorption
    232975 (Atp1a3)
   04978 Mineral absorption
    232975 (Atp1a3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    232975 (Atp1a3)
   04961 Endocrine and other factor-regulated calcium reabsorption
    232975 (Atp1a3)
   04964 Proximal tubule bicarbonate reclamation
    232975 (Atp1a3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    232975 (Atp1a3)
Enzymes [BR:mmu01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     232975 (Atp1a3)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   232975 (Atp1a3)
  Exosomal proteins of other body fluids (saliva and urine)
   232975 (Atp1a3)
  Exosomal proteins of colorectal cancer cells
   232975 (Atp1a3)
  Exosomal proteins of bladder cancer cells
   232975 (Atp1a3)
SSDB
Motif
Pfam: Cation_ATPase Cation_ATPase_C E1-E2_ATPase Cation_ATPase_N Hydrolase Hydrolase_3
Other DBs
NCBI-GeneID: 232975
NCBI-ProteinID: NP_001277398
MGI: 88107
Ensembl: ENSMUSG00000040907
UniProt: Q6PIC6 Q8R0E8
Position
7:complement(24677592..24705338)
AA seq 1013 aa
MGDKKDDKSSPKKSKAKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQE
ILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNL
YLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDL
VEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCV
EGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILS
LILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGST
STICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNR
AVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL
SIHETEDPNDNRYLLVMKGAPERILDRCATILLQGKEQPLDEEMKEAFQNAYLELGGLGE
RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAG
IKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDL
KDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADI
GVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPF
LLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLI
SMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQ
RKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSY
CPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY
NT seq 3042 nt   +upstreamnt  +downstreamnt
atgggggacaaaaaagatgacaagagctcgcccaagaagagcaaggccaaagagcgccgg
gacctggatgacctcaagaaggaagtggctatgacagagcacaagatgtcagtagaagag
gtctgccggaaatacaatactgactgcgtgcagggtctgacacacagtaaagcccaggag
atcctagcccgggatgggcctaacgccctcacaccaccgcccaccaccccagaatgggtc
aagttctgccggcagctgtttggtggcttctctatcctgctgtggatcggggcaatcctt
tgcttcctggcctatggcatccaggcagggacggaggatgacccttccggtgacaatctg
tacctgggcatagtgctggccgcagtcgtgatcatcaccggctgcttctcctactaccaa
gaagccaagagttctaagatcatggagtccttcaagaacatggtcccccagcaagccctt
gtgatccgggaaggtgaaaagatgcaggtgaatgcggaggaggtggtggtcggggacctg
gtggagatcaagggtggtgaccgggtgccagctgacctgcgcatcatctcggcccatggc
tgcaaggtggacaactcctccctgactggcgaatctgagcctcagacccgctccccggac
tgcacacacgacaaccccctggagactcggaacatcaccttcttttccaccaactgcgtg
gaaggcaccgctcggggtgtggtggtagccacaggtgaccgcaccgtcatgggccgcatt
gccaccctggcctcgggcttggaggtgggcaagacgcccatcgccattgagattgagcat
ttcatccagctcattacgggcgtggccgtgttcctgggcgtgtccttcttcatcctctct
ctcattctgggttacacctggctcgaggcagtcatcttcctcatcggcatcattgtggcc
aatgtcccagaggggctgctggctactgtcacggtgtgtctgacgctgaccgccaagcgc
atggctcgcaagaactgcctggtgaagaacctggaggcggtggagacgctgggctccacg
tccaccatctgctcggacaagaccggcactctcacccagaaccgcatgaccgtcgcccac
atgtggtttgacaaccagatccacgaggcagacaccacagaggatcagtcagggacctct
ttcgacaagagctcacacacctgggtggccctgtcccacatcgccgggctctgcaaccgg
gccgtcttcaagggcgggcaggacaacatcccagtactcaagagggacgtggccggtgat
gcctccgagtctgccctgcttaagtgcattgagctgtcctcgggttccgtaaagctgatg
cgagaacggaacaagaaagtggctgagattccgttcaactcgaccaacaaataccagcta
tccatccatgagactgaggatcccaatgacaaccggtacctgctagtgatgaagggcgcc
cccgaacgcattctggaccgctgtgccaccatcctcctgcagggcaaggagcagcctctg
gatgaggagatgaaggaggccttccagaatgcctacctggagcttggtggcctgggcgag
cgtgtgctgggtttctgccattactacctgcctgaggaacagttccccaagggctttgcc
tttgactgtgatgacgtgaacttcaccacagacaacctttgctttgtgggtctcatgtcc
atgattgaccctccccgggcagccgtccctgacgctgtgggcaaatgccgaagcgcaggc
atcaaggtcatcatggtcaccggcgatcaccccatcactgccaaggccattgccaagggt
gtgggtatcatctctgagggtaacgagactgtcgaagacatcgctgcccggctcaacatc
cctgtcagccaggtgaaccccagggatgccaaagcctgtgtgattcacggcaccgacctc
aaggacttcacctcggagcagattgacgagattctgcagaaccacaccgagatcgtcttt
gcccgaacctcccctcagcagaagctcatcatcgtggagggctgtcagagacagggagca
attgtggctgtgactggcgatggtgtgaatgactcccctgctctgaagaaggctgacatc
ggggtggccatgggcattgctggctctgatgtctctaagcaggctgccgacatgattctg
ctggatgacaactttgcttccattgtcactggtgtggaggaaggccgcctgatctttgac
aacctgaagaaatccatcgcctacactctgactagcaacatccctgagatcacacccttc
ctgctcttcatcatggctaacatcccactgcctcttggcaccatcaccatcctctgcatt
gacctgggtaccgacatggtccctgcaatctccctggcctacgaggctgccgagagcgac
atcatgaagaggcagcccaggaacccacgcacagacaaactggtcaacgaaaggctcatc
agcatggcctacgggcagattgggatgatccaggccctcggtggtttcttctcctacttt
gtcatcctggcagaaaatggcttcttgcccggaaacctggtgggcatccggctcaactgg
gatgatcgcactgtcaatgacctagaagacagttatgggcagcagtggacttatgagcag
aggaaggtggtagagttcacatgccacacagccttctttgtgagtatcgtggtggtccag
tgggctgacctgatcatctgcaagaccaggaggaactccgtcttccagcagggcatgaag
aataagatcttgatcttcggcttgtttgaggagacggccctcgctgccttcctgtcctac
tgcccaggcatggatgtggcccttcgcatgtaccctctcaagcccagctggtggttctgt
gccttcccctacagtttcctcatcttcgtctatgatgagattcgcaaactcatcctgcgc
aggaaccccgggggttgggtggagaaagagacctactattga

  All links  
Gene (44)   
   RefGene (39)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (24)   
   RefSeq(nuc) (8)   
   GenBank (8)   
   EMBL (8)   
Protein domain (6)   
   Pfam (6)   
All databases (83)   

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