KEGG   Mus musculus (house mouse): 239273
Entry
239273            CDS       T01002                                 
Symbol
Abcc4, ABCC4-N1, D630049P08Rik, MOATB, MRP4
Name
(RefSeq) ATP-binding cassette, sub-family C member 4
  KO
K05673  ATP-binding cassette, subfamily C (CFTR/MRP), member 4
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu01523  Antifolate resistance
mmu02010  ABC transporters
mmu04024  cAMP signaling pathway
mmu04976  Bile secretion
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    239273 (Abcc4)
  09132 Signal transduction
   04024 cAMP signaling pathway
    239273 (Abcc4)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    239273 (Abcc4)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    239273 (Abcc4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mmu02000]
    239273 (Abcc4)
Transporters [BR:mmu02000]
 ABC transporters, eukaryotic type
  ABCC (CFTR/MRP) subfamily
   ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
    239273 (Abcc4)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N AAA_16 MMR_HSR1 AAA_29 AAA_21 nSTAND1 RsgA_GTPase AAA_22 Dynamin_N AAA_23 T2SSE ABC_ATPase DUF87
Other DBs
NCBI-GeneID: 239273
NCBI-ProteinID: NP_001028508
MGI: 2443111
Ensembl: ENSMUSG00000032849
UniProt: E9Q236
Position
14:complement(118720104..118945475)
AA seq 1325 aa
MLPVHTEVKPNPLQDANLCSRVFFWWLNPLFKTGHKRRLEEDDMFSVLPEDRSKHLGEEL
QRYWDKELLRAKKDSRKPSLTKAIIKCYWKSYLILGIFTLIEEGTRVVQPLFLGKIIEYF
EKYDPDDSVALHTAYGYAAVLSMCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALR
LSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWVEIGISCLAG
LAVLVILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLIA
NLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTSYVLLGNEITASHVFVAMTLYGA
VRLTVTLFFPSAIERGSEAIVSIRRIKNFLLLDELPQRKAHVPSDGKAIVHVQDFTAFWD
KALDSPTLQGLSFIARPGELLAVVGPVGAGKSSLLSAVLGELPPASGLVSVHGRIAYVSQ
QPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQK
ARVNLARAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQALHEKITILVTHQLQYLKAA
SHILILKDGEMVQKGTYTEFLKSGVDFGSLLKKENEEAEPSTAPGTPTLRKRTFSEASIW
SQQSSRPSLKDGAPEGQDAENTQAVQPEESRSEGRIGFKAYKNYFSAGASWFFIIFLVLL
NMVGQVFYVLQDWWLSHWANKQGALNNTRNANGNITETLDLSWYLGIYAGLTAVTVLFGI
ARSLLVFYILVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTF
LDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSVVFLVLRRYFLETSRDVKRLESTTRSPV
FSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFV
IVVAFGSLVLAKTLNAGQVGLALSYALTLMGMFQWSVRQSAEVENMMISVERVIEYTDLE
KEAPWECKKRPPPGWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGAG
KSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNE
HTDEELWRALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKNNRILII
DEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYV
LLQNPESLFYKMVQQLGKGEAAALTETAKQVYFRRNYPDITFTSPAVMNTSNGQPSALTI
FETAL
NT seq 3978 nt   +upstreamnt  +downstreamnt
atgctgccggtgcacaccgaggtgaaacccaacccgctgcaggacgccaacctctgctcg
cgcgtgttcttctggtggctcaacccgctgtttaaaactggtcataagcggagactggaa
gaagatgacatgttctcagtgcttccagaagatcgctcaaagcacctcggagaggagctt
caacggtactgggataaagaacttctgcgagccaagaaggactcgaggaagccctcctta
acaaaggcaatcataaagtgttactggaagtcttacctgattttgggaatttttacgtta
attgaggagggcactcgagtagttcagcccttatttttagggaaaattattgaatatttt
gagaagtatgaccccgacgactcggtggctttgcatacagcttatggctacgcagcagtg
ctgtccatgtgcacgctcatcctggccatactacatcatttgtacttctaccacgtgcag
tgcgccgggatgaggctgcgggttgccatgtgccacatgatttaccggaaggcactccgg
ttaagtaactcggccatggggaagacaaccacaggccagatagttaacctgctgtccaac
gacgtgaacaaattcgaccaagtgacaatcttcttgcactttctgtgggcagggccgctg
caggccatcgcggtaaccgtcctcctctgggtggagataggaatctcctgcctggcgggc
ttggccgttctggttattcttctgcctctgcaaagctgcatcgggaagctgttctcgtca
ctgcggagtaaaactgcggctttcacggatgccaggatccggaccatgaatgaagtcata
acaggcatgaggataataaagatgtatgcgtgggagaaatcgtttgctgacctcattgcc
aatctgagaaagaaggagatttccaagattctgggcagctcctacctcagagggatgaac
atggcgtcgtttttcatcgcaaacaaagtcatcctgttcgtgaccttcactagctacgtg
ctgcttggcaatgagattacagctagccacgtgtttgtggccatgactctgtacggtgcc
gttcggttgacagtcaccctcttcttcccgtcagccattgagagagggtcagaggccatc
gtcagcattcggaggatcaagaactttctgttactcgatgaactaccacagcgcaaagcc
catgtaccatctgatggcaaagccattgtccacgtgcaagatttcaccgctttctgggac
aaggcactagacagtccaaccctgcaaggtctttcctttattgccaggcctggtgagttg
ttagccgtggttggcccagttggagcaggcaagtcgtcgctgttgagcgcagtgctgggt
gagctgcctcctgccagcgggctggtcagcgtgcacgggaggatcgcctacgtttctcag
cagccctgggtgttctcgggcaccgtgaggagcaatattttatttgggaagaaatatgag
aaggagcgatatgagaaagtgatcaaggcctgtgctctgaagaaggacctgcagcttctg
gaggacggggatctgacggttataggagaccggggagccacgctgagtggaggccagaaa
gctcgggtgaacctggcacgggccgtctaccaggacgccgacatctacctccttgatgat
ccgctcagcgctgtcgatgcagaagtgggcaagcacctgttccaactgtgtatctgtcag
gcgttgcacgagaagatcaccattttagtgactcaccagttacagtacctcaaagctgca
agccacatcctcatactcaaagatggtgagatggtgcagaaggggacttacacggagttt
ctgaaatctggtgtagattttggctccctgttaaagaaagaaaacgaggaagcagagccc
tccacagccccaggaaccccgacactcaggaaacgaaccttctccgaggcctcaatttgg
tctcagcagtcatccagaccctcgttgaaagacggggccccagagggccaagacgcagag
aacacgcaggcagtgcaacccgaggagagccgttcggaagggagaatcggcttcaaggcc
tacaagaattacttctcggcgggcgcatcctggttcttcatcattttccttgtgctgctt
aacatggtgggccaggttttctatgttcttcaggactggtggctttcccactgggcgaac
aagcaaggtgcactgaacaacaccagaaatgcgaatggaaatataacggagaccctagac
ctcagctggtacttaggaatttacgcaggtctaactgcggtcaccgtcctttttggcata
gcgagatccctactggtgttctatatccttgtgaacgcttcccagactttgcacaacagg
atgtttgagtccatactgaaggctcccgtgttgttcttcgacagaaatccaatcgggagg
attttaaatcgtttctccaaagacatcggacacatggatgatttgcttcccctgacgttc
ctggacttcatccagacgttgctcctcgtcgtaagtgtgatcgctgtggccgcggccgtg
atcccttggatcctcataccattggttccgctctcagtcgtcttcctggttcttcggaga
tacttcttagagacgtcacgggatgtcaagcgcctggaatccacaacacggagcccggta
ttctcccatttatcgtcctccctccagggactctggaccatccgggcttacaaagctgag
gagaggtgtcaggagctgtttgatgcacaccaggacttgcattcagaggcttggttcttg
ttcctgacgacatcgagatggttcgctgtgcgtctggacgccatctgcgccatctttgta
atcgtcgttgccttcgggtcccttgttctggcgaagactttgaatgctgggcaggttggc
ctggccttgtcctacgccctcacactcatggggatgttccagtggtctgtgcgacagagc
gccgaagtagagaatatgatgatttcagtggagagagtgattgagtacacggacctagag
aaggaggcgccttgggagtgcaagaagcgcccacccccaggctggccccacgagggagtc
atcgtcttcgacaatgtgaacttcacctacagcttagatgggcctctggttctgaagcac
ctgactgcgctcatcaagtccagggaaaaggttggaattgtgggcagaaccggagctggg
aaaagctccctcatctcggccctcttcaggctgtcagaacccgaggggaaaatctggatc
gataagatcttgacaaccgaaattgggcttcacgacttaaggaagaaaatgtcaatcata
ccacaggaacctgttctgttcactggaaccatgaggaaaaacctggaccccttcaatgag
cacacggacgaggagctgtggagggccttggaggaggtacaacttaaagaggccattgaa
gatcttcctggaaaaatggatactgaattagcagaatctggatccaatttcagtgttgga
cagagacagttagtgtgccttgcaagggccattctaaagaataaccgaatactgatcatt
gatgaagcaactgcaaatgtggacccaagaacggatgagttaatacaacagaagatccgg
gagaagtttgcccagtgcacagtgctcaccattgctcacagactgaacaccatcattgac
agtgacaagataatggttttggattcaggaagactgaaagaatatgatgagccgtatgtc
ttgctgcagaatccagagagcctcttttacaagatggttcagcaactgggcaagggcgaa
gccgctgccctcaccgaaacagcaaaacaggtatacttcagacggaattacccagatatt
acattcaccagccccgcggttatgaacacctccaatggacagccctcggccttaacaata
tttgaaacagcattgtga

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