KEGG   Mus musculus (mouse): 269523
Entry
269523            CDS       T01002                                 

Gene name
Vcp, 3110001E05, CDC48, p97, p97/VCP
Definition
(RefSeq) valosin containing protein
  KO
K13525  transitional endoplasmic reticulum ATPase
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04141  Protein processing in endoplasmic reticulum
mmu05014  Amyotrophic lateral sclerosis
mmu05134  Legionellosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    269523 (Vcp)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    269523 (Vcp)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    269523 (Vcp)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    269523 (Vcp)
   04131 Membrane trafficking [BR:mmu04131]
    269523 (Vcp)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    269523 (Vcp)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Ran-mediated transport factors
     269523 (Vcp)
Membrane trafficking [BR:mmu04131]
 SNARE
  SNARE associated proteins
   Others
    269523 (Vcp)
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    269523 (Vcp)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   269523 (Vcp)
SSDB
Motif
Pfam: AAA AAA_lid_3 CDC48_N RuvB_N AAA_16 CDC48_2 AAA_2 AAA_5 AAA_33 AAA_22 TIP49 Vps4_C AAA_18 AAA_14 RNA_helicase Mg_chelatase IstB_IS21 Parvo_NS1 AAA_28 AAA_7 ATPase ATPase_2 Bac_DnaA ABC_tran AAA_17 DUF815 AAA_24 Viral_helicase1 TsaE Sigma54_activat NACHT NB-ARC ResIII DUF2075 Zeta_toxin UFD1 DUF3944
Other DBs
NCBI-GeneID: 269523
NCBI-ProteinID: NP_033529
MGI: 99919
Ensembl: ENSMUSG00000028452
Vega: OTTMUSG00000006688
UniProt: Q01853
Structure
PDB: 

Position
4 A5; 4 22.95 cM
AA seq 806 aa
MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLK
GKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPID
DTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDT
VIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRG
ILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAI
IFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRF
GRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAAL
QAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIG
GLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFI
SIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRV
INQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKAN
LRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAM
EVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGG
AGPSQGSGGGTGGSVYTEDNDDDLYG
NT seq 2421 nt   +upstreamnt  +downstreamnt
atggcctctggagccgattcaaaaggtgatgatttatcaacagccattctcaaacagaag
aaccgacccaatcggttaattgttgatgaagccatcaatgaagataacagcgtggtgtcc
ttgtcccagcccaagatggatgaactgcagttgttccgaggtgacacggtgttgctaaaa
ggaaagaaaagacgggaagctgtatgcattgttctttctgatgacacgtgttctgatgag
aagattcgaatgaatagagttgttcggaataacctccgagttcgcctaggagatgtcatc
agcatccagccatgccctgatgtaaagtatggcaaacgtatccacgttctacccatcgat
gacacagtggaaggcatcactggcaatctctttgaggtataccttaagccgtacttcctg
gaagcttatcggcccatccgtaaaggagatatttttcttgtccggggtgggatgcgtgct
gtggagttcaaagttgtagagacagatcccagcccttactgtattgttgctccagacaca
gtgatccactgtgagggggagccaatcaagcgagaggatgaggaggaatccttgaatgaa
gtaggctatgatgacatcggtggttgcaggaagcagctagctcagataaaggagatggtg
gagctgccactgagacatcctgcgctctttaaggcgattggtgtaaagcctcctcgggga
atcttgttgtatgggcctcctgggacagggaagaccctgattgctcgagctgtggcaaat
gaaactggagccttcttctttctgatcaatggtcctgaaatcatgagcaaattggctggt
gagtctgagagcaaccttcgtaaagcctttgaggaagctgaaaagaatgctcctgctatc
atcttcatcgatgagcttgatgccattgcacccaaaagagagaaaactcatggggaagtg
gagcgtcgcatcgtgtctcagttgttgaccctcatggatggcctaaagcagagagcacat
gtgatagttatggcagcaaccaatagacccaacagcattgacccagccctacggcgattt
ggtcgctttgacagagaggtagatattggaatacctgatgctacaggacgtttggagatt
cttcagatccataccaagaacatgaaactggcagatgatgtggacttggaacaggtagcc
aatgagactcatggtcatgttggtgctgatttggcagccctatgttcagaggctgctctg
caggccatccggaaaaaaatggacctcattgacctagaagatgagaccattgatgctgag
gtcatgaattccctggcagttactatggatgacttccggtgggctttgagtcaaagcaac
ccatcagcacttcgggaaactgtggtagaggtgccacaagtaacctgggaagatattgga
ggcctggaggatgtcaaacgtgagcttcaggagttggttcagtatcctgtggaacatcca
gacaaattcctcaaatttggcatgactccctccaaaggcgttcttttctatggacctcct
ggctgtgggaaaaccttactggctaaagccattgctaatgaatgccaggccaacttcatc
tccatcaagggtcctgagctgcttaccatgtggtttggggaatctgaggccaatgtccgg
gaaatttttgacaaggcacggcaagctgccccctgtgtactcttctttgatgagttagat
tcaattgccaaggctcgaggtggtaatattggagatggtggtggagctgctgaccgagtc
atcaatcagatcctgacagaaatggatggcatgtctacaaaaaagaatgtgtttatcatt
ggagctaccaacaggcctgacatcattgatcctgctatcctaagacctggccgtctagat
cagctcatttatatcccacttcctgatgagaagtcccgtgttgccatcctaaaagccaat
ctgcgaaagtccccagttgccaaggatgtggatttggagttcctggctaagatgactaat
ggcttttctggagctgatttgacagaaatttgccaacgggcttgtaaactggccattcgt
gaatctattgagagtgagattaggcgagaacgagagaggcagacaaatccatcggctatg
gaggtagaagaggacgatccagtgcctgagatccgcagagatcactttgaggaagccatg
cgttttgcccgacgttctgtcagcgataatgacattcggaagtatgaaatgttcgcccag
acactgcagcagagtcgaggttttggcagcttcagattcccttcagggaaccagggtgga
gctggtcccagccagggcagtggaggtggcacaggtggcagtgtgtacacagaagacaat
gacgatgacctgtatggctaa

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