KEGG   Mus musculus (house mouse): 286940
Entry
286940            CDS       T01002                                 
Symbol
Flnb, Fln-b
Name
(RefSeq) filamin-B isoform a
  KO
K27392  filamin-B
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04510  Focal adhesion
mmu04518  Integrin signaling
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04518 Integrin signaling
    286940 (Flnb)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    286940 (Flnb)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:mmu04812]
    286940 (Flnb)
Cytoskeleton proteins [BR:mmu04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     286940 (Flnb)
  Intermediate filaments
   Intermediate filament-binding proteins
    286940 (Flnb)
SSDB
Motif
Pfam: Filamin Ig_GEX2_N CH Y_Y_Y Invasin_D3 GBD_IRG7_N CFSR PapC_N CH_2
Other DBs
NCBI-GeneID: 286940
NCBI-ProteinID: NP_001074896
MGI: 2446089
Ensembl: ENSMUSG00000025278
UniProt: Q80X90
Position
14:complement(14518185..14651852)
AA seq 2602 aa
MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQK
RMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILH
YSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAP
GLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKA
KLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNK
EEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAK
GPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKP
VQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTK
AAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFE
VQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQN
DGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGC
TINNPAEFIVDPKDAGSAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAV
VWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVG
IKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVD
PSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPLPGEAVKDLDIID
NYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGK
DQEFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTY
DGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGP
CEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASG
PGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAG
MYTLTMKYGGELVPHFPAWVKVEPAIDTSGIKAFGPGIEGKDVFREATTDFTVDSRPLTQ
VGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKV
AVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKD
GSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLSSCVRACIP
QSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYIVSVKYADE
EIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQE
GKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLAT
GPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAK
PGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMN
GLGFKPFDLVIPFAVRKGEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHI
KYRGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEG
PSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDNRRCSQVKL
GSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKK
NGNHVANSPVSIMVVQSEIGDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVE
GPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVRESIT
RTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQ
EMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTRE
AGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPV
IAPSDDARCLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEP
DKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLETGTTG
IQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLIGVKYGGPN
HISRSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGA
GLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGD
YVLAVKWGEEHIPGSPFHVTVP
NT seq 7809 nt   +upstreamnt  +downstreamnt
atgccggtgacggagaaagacctggcggaggacgcgccgtggaagaagattcagcagaac
acgttcacgcgctggtgcaacgagcacctcaagtgtgtgaataaacgcatcgggaacctg
cagaccgacctgagcgacgggctacggctcatcgcgctgctcgaggtgctcagccagaag
cgcatgcaccacaagtaccatcagcggcccaccttcagacagatgaagctggagaatgtg
tctgtggctctggagttcctagaccacgaaagcattaagctcgtgtccattgacagtaaa
gccatcgtggatgggaacctgaagctcatcttgggcctggtatggactttgatccttcac
tactccatctccatgcccgtatgggaagatgaaggggatgatgatgccaagaagcagaca
ccaaagcagaggctactgggatggattcagaacaagattccatacttgcccatcactaac
tttaaccagaactggcaagatggcaaagccttaggagccctggtagacagctgtgctcca
ggtctgtgcccagactgggaatcctgggacccacggaagccggtggataatgcccgagaa
gccatgcagcaggccgatgactggctgggcgtcccacaggtcatcactcctgaggagatt
attcacccggacgtggacgagcactctgtgatgacctacctgtctcagttccccaaagcc
aagctcaagccaggtgctcctcttaaacccaaactcaacccaaagaaagcccgagcctat
ggcagaggaatcgaacctactggaaacatggtgaagcagccagccaaattcacggtagat
accatcagcgctggacaaggagatgtgatggtgtttgttgaggacccagaaggaaacaag
gaagaggcacgtgtgaccccagacagtgacaagaacaagacatactctgtggagtatctg
cccaaagtcaccggcctgcataaagtcatcgtcctctttgcaggacagcacatttctaag
agcccatttgaagtgaatgttgacaaagcccaaggagatgccagcaaagtcactgcaaaa
ggcccagggctggaaactacagggaacattgccaacaagcctacctattttgacatctac
acagctggagctggcgtgggggacatcggcattgaggtggaggatccccagggcaagaac
agcgtggagctgctggtggaagacagaggaaaccaggtgtatagatgtgtctacaaacca
gtgcagcctggcccccatgtggtcaaggtctcctttgctggggatgccattcccaagagt
ccctttggtgtacaaattggggaagcctgcaacccaaatgcctgcagagccagcggccga
ggtctgcagcccaaaggtgtccggatccgggagactgcagactttaaggtggacaccaag
gctgctggaagcggagagcttggtgtaactgtgaagggccctaagggcctggaggagctg
gtcaaacaaaagggctttctggatggggtctactcatttgagtactaccccagcacacca
gggaaatacagcgttgcagttacctggggggggcaccacattcccaagagcccctttgaa
gttcaagttggccctgaagcaggcatgcagaaagtccgtgcatggggccctggactccac
ggcggcattgttggtcggtcagcagattttgtggtggaatccattggttctgaggttgga
actctgggatttgccattgaaggcccttcccaagcaaagatcgagtatgatgatcagaac
gatggctcgtgtgatgtcaaatactggcccaaggagcctggagaatacgccgttcacatc
atgtgcgacgacgaagacatcaaggacagcccatacatggctttcatccaccctgccaca
ggagactacaacccagatctagtccaagcctatgggccgggtttggagaaatctggttgt
actatcaacaacccagcagagttcattgtggatcctaaggatgccgggagtgctccctta
aagatactggcgcaggatggggaaggccagcccattgacatccagatgaagagtcggatg
gacggcacttatgcttgctcatataccccacttaaagccatcaagcacaccatcgctgtg
gtctggggaggtgtgaacataccacacagcccctacagggtcaacattgggcaaggtagc
catccccaaaaggtcaaagtgtttggcccaggcgtggagaggagtggtctgaaggcaaat
gagcctactcactttacagtggattgcacggaggccggggaaggtgatgtcagtgttggt
atcaagtgcgatgcccgagttttaagtgacgatgaggaagatgtcgattttgacattatt
cacaatgccaatgacacattcactgtcaaatacgtacctcctgcccctgggcggtatacc
atcaaagttctctttgcatctcaggaaatccccgccagccctttcagagtcaaagttgac
ccttcccatgacgccagcaaggtgaaggcagaaggccccgggttgagtaaagcaggcgtg
gaaaatgggaagccaacccacttcactgttcacaccaagggagccggaaaagctccgctc
aacgtgcagttcagcagcccccttcctggggaggcagtgaaggacttggatatcattgat
aattatgactactcacatactgttaaatacaccccaacccagcagggcaacatgcaggtt
ctagtgacttatggtggcgatcccattcctaaaagtcctttcactgtgggcgttgctgcg
ccactggatctgagcaagataaaaattaatggactggaaaacagagttgaggttggaaag
gaccaggaatttgccattgacaccaacggggcaggaggccaggggaagctggatgtgacc
atcctgagcccttctcggaaggtggtgccatgcttggtagcaccagtggctggcagggaa
tgcagcacagccaaattcatccctcgggaggaggggctgtttgctgtagatgtgacctat
gatggacacccagtgcccgggagcccctatactgtggaggcctcactaccaccagatccc
accaaggtgaaggcccacggtcctggccttgaaggaggtcttgtaggcaagcccgctgag
ttcaccattgacactaaaggagctggaactggaggtttgggcctaactgtggaaggtcca
tgtgaggccaaaatcgaatgctcggataacggtgacgggacctgctccgtctcctacctt
cccacaaaacccggagaatactttgtcaacattctctttgaagaagtccacattcctgga
tctcccttcaaagccgacattgaaatgccgtttgacccctctaaggttgtagcgtcagga
ccaggacttgaacacggaaaagtgggtgaacccggaatcctttgcgttgattgttcagaa
gcagggcctgggactctgggccttgaagccgtctcagactcaggggcgaaagctgaagtg
tccatccagaacaataaagatggcacctacgctgtgacctatgtgcctctgacagctggc
atgtacacactgaccatgaagtatggtggtgagcttgtaccacactttcctgcctgggtc
aaggtggagccagccatagacactagtgggatcaaagcctttgggccaggaatcgaaggc
aaggacgtgtttcgggaggccacaacggacttcacggttgactcgaggccccttacccag
gttggaggtgaccatatcaaagctcaaattaccaacccctcgggggcctccaccgagtgc
tttgtcaaggacaatgctgatgggacctatcaggtcgaatacacgccctttgagaaaggt
ttccatgtagtggaggtgacatacgatgatgtgcccatcccaaatagcccattcaaagtg
gctgtcactgaaggctgccagccatctcgggtccatgcgcaaggccctggactgaaagag
gcgtttaccaacaaatctaatgtcttcacagtggtaaccaggggagcagggatcggtggg
cttggcataactgtggaggggccgtcggagtcaaagataaactgcagagacaacaaggat
ggcagctgcagtgctgagtacattcctttcgctccaggggattatgacgtcaatatcacg
tacggaggcgtccacatccctggcagccccttcagagttccttcaaaagatgttgtggat
cccagcaaggtcaagattgctggccccggtctgagctcctgtgtccgagcatgcatcccg
cagtccttcacagtggacagcagcaaggctggcctagctcccctggaagtgagggtcctg
ggcccaagaggcctcgtggagccggtgaatgtggtagataatggggacggcacccacaca
gtgacctacacgccatctcaggaggggccctacattgtttccgtcaaatatgctgatgaa
gagatcccccgaagtccctttaaggtcaaggttcttcccacatacgatgcaagcaaagtg
acagcctctgggcctggcctcagcgcctatggggtacccgccagcctacctgtggagttc
gccattgatgccagagatgctggcgaaggcctgcttgctgtccagatcacggaccaggag
ggaaagcctcaaagagctactgtccacgacaacaaagatggcacatatgccgttacctat
atccctgataagaccggacgctatatgattggagtcacctatggtggagacaacattcca
ctttctccttaccgtatccgggccacacagacaggcgatgccagcaagtgcttggccaca
ggtcctggtattgcccccactgtgaaaactggcgaggaggtgggctttgtagtggacgct
aagactgcagggaaggggaaagtaacctgcgtgattctgaccccagatggcaccgaggct
gaggctgacgtcattgaaaatgaagatggcacctatgacattttctacactgctgccaag
ccaggcacctatgttatctatgtgcgctttggtggcgttgatattcccaatagccccttc
acagtcatggccaccgatggggaagtcacagccatggaggaggcaccggtaaatgcatgt
ccccctggattcaggccctgggttacagaagaggcctatgtccctgtgagtgacatgaac
gggctaggcttcaagccctttgacttggtgattccatttgccgtcaggaaaggagaaatt
acaggcacggtgcatatgccttctgggaagaaggctacacctgagattgtggacaacaag
gacggcacggtcactgtgagatacgcgcccactgaagtcggcctccacgagatgcacatc
aagtacaggggcagccacatcccggagagccccctgcagttctacgtgaactaccccaac
agtgggagtgtgtctgcttatggtccaggccttgtgtatggagtagccaacaaaactgcc
accttcaccattgtcacagaggatgcgggagaaggtggtctggacttggctattgaagga
ccctcgaaagcagagatcagctgcattgacaacaaagacgggacatgtacagtgacctac
ctacccaccttgccaggggactacagcattctggtcaagtacaatgacaaacatattcct
ggcagccccttcactgccaagatcacagatgataacagacgctgctcccaagtgaagctg
ggctcagctgctgacttccttctggacatcagtgagacagaccttagcacactgacagcc
agtatcaaggccccatctggacgtgacgagccctgtctgctaaagaggctacccaacaac
cacattggcatttccttcatcccccgagaagtgggtgagcatctagtcagcatcaagaaa
aacggtaaccacgtggccaacagccctgtgtccattatggtggtccagtctgaaattggt
gatgcacgccgagccaaagtctatggccaaggcctgtcagaaggccggacttttgagatg
tcagacttcatcgtggacacaagagatgcaggctatggtggcatatccttggcagtagaa
ggacccagcaaggtggacatccaaacagaggacctggaggacggcacctgcaaggtgtcc
tacttccccactgtgcccggggtctatatcgtctccaccaaatttgctgacgagcatgtg
cctggaagcccattcactgtgaagatcagtggcgagggaagagtcagagagagcatcacc
cggaccagccgggctccggctgtggccacggttggcagtatctgtgacctgaacctgaag
atcccggagatcaacagcagtgacatgtctgcccatgtcaccagcccctctggccatgtc
actgaggcagagattgtgcccatgggaaagaactctcactgtgtcagatttgtgccccag
gagatgggcgttcacactgtcagcgtaaagtaccgcggacagcacgtaacaggaagcccg
ttccagttcaccgtggggccccttggcgaagggggtgcccacaaggtccgggcaggaggc
cctggcctggagaggggagaagcaggcatcccagctgagttcagcatctggacccgggaa
gcaggtgctggcggcctctccattgctgttgagggccctagtaaggccgagatcacattc
gatgaccataaaaatgggtcatgcggtgtgtcttatattgcccaagagcctggtaactac
gaggtgtctatcaagttcaacgacgagcacatcccggacagcccttacctggtgcccgtc
atcgcgccctcagacgacgctcgctgcctcactgttctgagccttcaggaatcaggatta
aaagttaaccagccagcgtcctttgctataaggttgaatggtgcgaaagggaagattgat
gcaaaggtgcacagcccctcaggagccgtggaggaatgccacgtgtctgaactggagcca
gataagtatgccgttcgcttcatcccgcatgagaatggcatccacacgatcgatgtcaag
tttaacgggagccacgtggtcgggagccctttcaaagtacgtgtaggagagcctggccag
gcaggcaatcctgctctagtgtcagcctacggtgctgggcttgagacgggcaccacaggt
atccaatcagaattcttcatcaataccactcaggcaggcccagggacattatctgtcacc
attgaaggaccatccaaggtcaaaatggattgccaggaaatcccagaggggtacaaagtc
atgtacactcccatggctcctggaaattacctgattggtgtcaaatatggcgggcccaac
cacatctcgaggagtccattcaaggccaaggtgacaggccaacgtctggtcagcccaggc
tcagccaacgagacctcctccatcttggtggagtccgtaaccagatcctcaacggaaacg
tgctatagcgccattcccaagtcgtcctccgatgccagcaaagtgacctccaagggcgca
ggcctgtcaaaggcttttgtgggccagaagagttctttcctggtggactgcagcaaagct
gggtccaacatgctgttgattggggtccatgggcccaccaccccctgtgaagaggtctcc
atgaagcatgtgggcaagcaacagtacaacgtcacctacgtcgtcaaggagaggggcgat
tacgttctggctgtgaagtggggggaagagcacatccccggtagcccctttcatgtcacc
gtgccttaa

  All links  
Gene (22)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (81)   
   RefSeq(nuc) (3)   
   GenBank (39)   
   EMBL (39)   
Protein domain (9)   
   Pfam (9)   
All databases (117)   

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