KEGG   Mus musculus (mouse): 381022
Entry
381022            CDS       T01002                                 

Symbol
Kmt2d, ALR, BC032281, BC058659, C430014K11Rik, KMT2B, Ml, Mll2, Mll4
Name
(RefSeq) lysine (K)-specific methyltransferase 2D
  KO
K09187  [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00310  Lysine degradation
mmu01100  Metabolic pathways
mmu04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    381022 (Kmt2d)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    381022 (Kmt2d)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    381022 (Kmt2d)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     381022 (Kmt2d)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     381022 (Kmt2d)
   HMT complexes
    MLL-HCF complex
     381022 (Kmt2d)
SSDB
Motif
Pfam: PHD FYRC FYRN SET zf-HC5HC2H zf-HC5HC2H_2 HMG_box DUF4757
Other DBs
NCBI-GeneID: 381022
NCBI-ProteinID: NP_001028448
MGI: 2682319
Ensembl: ENSMUSG00000048154
Vega: OTTMUSG00000043160
UniProt: A0A0A0MQ73
Position
15; 15 F1
AA seq 5588 aa
MDSQKPPAEDKDSDPAADGLAAPEKPGATEPDLPILCIGEVSVPGSGGSRPQKPPHDCSR
GPARRCALCNCGEPGLHGQRELQRFELPSDWPGFPVVPSGGNSGPCEAVLPKEDASQIGF
PEGLTPAHLGEPGGHCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCARFGA
SVPCRSPGCSRLYHFPCATASGSFLSMKTLQLLCPEHSDGAAHLEEARCAVCEGPGQLCD
LLFCTSCGHHYHGACLDTALTARKRASWQCPECKVCQSCRKPGNDSKMLVCETCDKGYHT
FCLKPPMEDLPAHSWKCKTCRLCRACGAGSAELNPNSEWFENYSLCHRCHKAQGSQPVTS
VAEQHPAVCSRLSPPEPGEIPIDAPDALYVACQGQPKGGHVTSMQPKELAPLQCEAKPLG
RAGTQLEAQLEAPLHEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPTEESPLSPPP
ESSPFSPLEGCPPSPALDTPLSPPPEASPLSPPFEESPLSPPPEELPSSPPPEASRLSPP
PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEDSPLSPPPEASRLSPPPEDSPM
SPPPEDSPMSPPPEVSRFLPLPVLSHLSPLPEVSRLSPPPEESPLSPPPEDSPASPPPEA
SRLSPPPEDSPASPPPEASRLSRPREDSPASPPPEDSLVSLPMEESPLSPLPEELRLCPQ
PEEPYLSPQPEEPRLCPQPEELPLSPQSEEPCLSPVLVEPGPSSQPEEPHLSPVPQEPHL
SPQPEEPHLSPQPQQLHLSPHSEEPCLSPMPEEPCLSPQPEELNGPPQPAEPPEEPSQSS
APKELSLFSPSGEPPLPPMLGEPALSEPGEPPLSPLPEELPLSLSGEPVLSPQLMPPDPL
PPPLSPIIPAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEP
VPPMILPPSPGSPLGPASPILMERLPPPCSPLLPHSLPPPTPPPSHCSPPALPLSVPSPL
SPVQKAVDVSDEAELHEMETDKGPEPECPALEPRATSPLPSPLGDLSCPAPSPAPALDDF
SGLGEDTAPLDGTGQMSGSLAGELKGSPVLLDPEELTPVTPMEVYGPECKQAGQGSPCEE
QEEPGAPMAPMPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGV
STDVSPARDEGSLRLCTDSLPETDDSLLCDTGTATSGGKAEGDKGRRRSSPARSRIKQGR
SSSFPGRRRPRGGAAHGGRGRGRARLKSTTSSVETLVADIDSSPSKEEEEEDDDTMQNTV
VLFSNTDKFVLMQDMCVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRC
VECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAAS
PGFHCEWQNSYTHCGPCASLVTCPVCHAPYVEEDLLIQCRHCERWMHAGCESLFTEDEVE
QAADEGFDCVSCQPYVVKPVVPVAPPELVPVKVKEPEPQFFRFEGVWLTETGMAVLRNLT
MSPLHKRRQRRGRLGLPGEAGLEGSEPSDALGPDDKKDGDLDTDDLLKGEGGVEQMECEI
KLEGPASPDVELGKEETEESKKRKRKPYRPGIGGFMVRQRKSHTRVKRGPAAQAEVLSGD
GQPDEVMPADLPAEGSVEQSLAEGDEKKKQQRRARKKSKLEDMFPAYLQEAFFGKDLLDL
SRKALFAVGVGRPGFGLGASKPRADGGSDRKELMTAMHKGDDGPDVADEESHGPEGTADL
PGLEDGGVKASPVPSDPEKPGTPGEGVLSSDLDRIPTEELPKMESKDLQQLFKDVLGSER
EQHLGCGTPGLEGGRTSLQRPFLQGGLALGSLPSSSPMDSYPGLCQSPFLDSRERGGFFS
PEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLY
ANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRISKVQKQAESQ
ISKQAKMGDIARKTDRPALHLRIPSQPGALGSPPPAAAPTIFLGSPTTPAGLSTSADGFL
KPPAGTVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYAPEPRFSAAPPTYPPYPSPT
GAPAQPPMLGTTTRPGTGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV
AGGKASEPLLSPPPFGESRKSLEVKKEELGASSPGYGPPNLGCVDSPSAGPHLGGLELKA
PDVFKAPLTPRASQVEPQSPGLGLRAQEPPPAQALAPSPPSHPDVFRSGPYPDPYAQPPL
TPRPQPPPPESCCAPPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPR
FQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGPLAHTPLGAGGFPAALPSGPA
GELHAKVPSGQPTNFARSPGTGTFVGTPSPMRFTFPQGVGEPSLKPPVPQPGLPSPHGIN
SHFGPGPTLGKPQSTNYAVATGNFHPSGSPLGPNSGPTGEGYGLSPLRPASVLPPPAPDG
SLPYLTHGASQRVGITSPVEKREDPGATMSSSSLATPELSSAQDAGISSLSQTELEKQRQ
RQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGNWGAEPSSPAFEQLSRGQTPFTGS
QDRSSIVGLPASKLGGPTLGPGAFSSDDRLARPLPPATPSSMDMNSRQLVGGSQAFYQRT
PYPGSLPLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLWQQQQQQQQQQQQQAAAAAAAT
SMRLAMSARFPSTPGPELGRQALGSPLAGIPTRLPGPAEPVPGPAGPAQFIELRHNVQKG
LGPGVSPFPGQGPPQRPRFYPVSEELHRLAPEGLRGLAVPGLPSQKPSALPAPELNNSLH
QTPHAKGPALASGLELVSRPPSNTELSRPPLALEAGKLPCEDPELDDDFDAHKALEDDEE
LAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNE
HLRLVESANEKAEREALLRGVEPVSLGPEERPPPAPDNSEPRLTSVLPEVKPKVEEGGRH
PSPCQFTINTPKVEPAPPATSLSLGLKPGQTVMGTRDTRGGVGTGSFPSSGHTAEKGPFG
ATGGTPAHLLNPSSLSGPAASSLLEKFELESGALTLPSGHAAAGDELDKMESSLVASELP
LLIEDLLEHEKKELQKKQQLSAQTVLPAQQQQQQQQQQQQQQQQHTLLPTPGPAQALPLP
HEPGPPQQLALGIGSTRQPGLGQSMVPIQPPAHALQQRLAPSVAMVSNQGHMLSGQQAGQ
TGLVPQQSSQPVLAQKPMSAMPASMCMKPQQLAMQQQQLANSFFPDTDLDKFAAEDIIDP
IAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGSGSDLQNHVAPGSGQERN
AGDPAQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALC
AKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQ
QQQQQQQQQQHSAVLAVSPSQNPRVLTKLPGQLLPAHGLQPPQAPPGGQAGGLRLPPGGM
VLPGQSGGPFLNTTLAQQQQQQHSGVAGSLTGPPGSFFPGNLALRSLGPDSRLLQERQLQ
LQQQRMQLAQKLQQQQQQQQQQQQQQHLLGQVAIQQQQGPGVQNQALGPKPQGLLPPSNH
QGLLVQQLSPQQSQGSQGLLGPAQVTVLQQQQQQQQHSGALGPQGPHRQVLMTQSRVLSS
PQLAQQGHSLMGHRLLTAQQQQQQQQQQQQQQQQQQQQQQQQQGSMTGLSQLQQGMMSHG
GQPKMSAQALGSLQQQQQQLQQQQMLQQQQLQQQQQQLQQQQQQQQLQQQQQQQLQLQQQ
QQQQQQHLQHQQQQQQQLQQQQQLQQQQQQQLHLQQQLHQQQQLQLQQQQMGLLNQNRTL
LSPQQQQQQQQQQQQQQQQQQQQQQQQQQVTLGPGLPVKPLQHFSSSGALGPTLLLTGKE
QNNAETALPSEVTEGPSTHQGGPPAVGTAPEPMSVEPGEVKPSISGDSQLLLVQSQAQSQ
ATSVQLQPPLRLPGQPQPQVNLLHTAGGGSHGQQLGSGSSSESPAVPHLLAQPSVSLGEQ
PGPMAQNLLGSQQPLGLDRPIQNNTGSQPPKSGPAPQSGQGPPGAGVMPTVGQLRAQLQG
VLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPFQEPGTQPSPLQGLLGCQPQP
GGFSVSQTGPLQELGAGSRPQGPPRLPVPQGALSTGPVLGPAHPTPPPSSPQEPKRPSQL
PSPSAQLTPTHPGTPKPQGPALELPPGRVSPAAAQLADTFFGKGLGPWDPSDNLTEAQKP
EQSSLVPGHLDQVNGQVVHEPSQLSIKQEPREEPCALGAQTVKREANGEPAGAPGTSNHL
LLAGSRSEAGHLLLQKLLRAKNVQLGAGRGPEGLRAEINGHIDSKLSGLEQKLQGTSSNK
EDAATRKPLPAKPKRVQKTSDRLPSSRKKLRKEDGVRANEALLKQLKQELSQLPLTEPTI
TANFSLFAPFGSGCLVSGQSQLRGAFGSGALHTGPDYYSQLLTKNNLSNPPTPPSSLPPT
PPPSVQQKMVNGVTPSDELGERPKDTASAQDSEGALRDAAEVKSLDLLAALPTPPHNQTE
DVRMESDEDSDSPDSIVPASSPESILGEEAPRFPQLGSGRWEQDNRALSPVIPIIPRTGI
PVFPDTKPYGVLDLEVPGKLPATAWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSM
KIPNSYEVLFPDGPARAGLEPKKGEAEGPGGKEKGLSGKGPDTGPDWLKQFDAVLPGYTL
KSQLDILSLLKQESPAPEPSIQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPP
AEPMVELQAERPAEPPIPSPLPLASSPESARPKPRARPPEESEDSRPPRLKKWKGVRWKR
LRLLLTIQKGSGHQEDEREVAEFMEQFGTALRPSKVPRDNRRCCFCHEEGDGATDGPARL
LNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRC
PNVYHFACAIRAKCMFFKDKTMLCPVHKIKGPCEQELSSFAVFRRVYIERDEVKQIASII
QRGERLHMFRVGGLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLRTNNRRCCYR
CSISENNGRPEFVIKVIEQGLEDLVFTDASPQAVWNRIIEPVAAMRKEADMLRLFPEYLK
GEELFGLTVHAVLRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTGCARSEPKILTHY
KRPHTLNSTSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVYLARSRIQGL
GLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGP
ARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGA
WNCRKWMN
NT seq 16767 nt   +upstreamnt  +downstreamnt
atggacagccagaagccgcctgctgaagataaagattcagacccagcagctgatggactt
gcagcccccgagaagccaggtgccactgagccagaccttcccattctgtgtatcggggag
gtctccgtccccggttctgggggttccaggcctcagaagcctcctcatgactgcagtagg
ggtccagcacggcgttgtgctctctgtaactgcggggagcccggtctgcatgggcagagg
gagctgcagcgctttgagttgccatctgactggcccgggtttccagtggtaccctctggg
ggaaactcaggtccctgtgaggcagtgctgcccaaggaggacgcatcacaaattggtttc
cctgagggtcttacgcctgcccacctaggagagcctggagggcactgctgggcacatcat
tggtgtgcagcgtggtcagcaggcgtatgggggcaggagggcccagaactatgtggtgtg
gacaaggccatcttctcagggatctcacagcgctgctcccactgcgccaggttcggtgcc
tccgttccttgccgctcacccggatgttcccggctttaccactttccctgtgcaactgcc
agtggttccttcttatccatgaaaaccctgcagctgctctgcccagagcacagtgatgga
gctgcacatttggaggaggctcgctgtgcagtgtgtgaggggccagggcagctgtgtgac
ttgctcttctgtaccagctgtgggcatcactatcatggagcctgtctggacactgctctg
actgcccgcaagcgtgccagttggcagtgccctgaatgcaaagtgtgccaatcgtgcagg
aaacctgggaatgattctaaaatgttggtgtgtgagacatgtgacaaagggtatcatact
ttctgcttaaaaccgcctatggaggacctgcctgctcactcgtggaaatgtaagacatgc
cggctatgtcgggcctgtggggccggctcagcagaactgaatcccaactctgagtggttt
gagaactattcactctgtcaccgctgtcataaagcccagggaagccagcctgtcacgtct
gttgccgagcagcacccagctgtctgtagcagattgtcccccccagagcctggtgagatc
cccattgatgcgccggatgctctgtacgttgcatgccaagggcagccaaagggtgggcat
gtgacctctatgcaacccaaggaactggcgcccctgcaatgtgaagccaaaccactaggg
agagcagggacccaacttgaagcccagttggaggctcccctgcatgaggagatgccactg
ctgcccccgcctgaggagtcacccctgtctccaccacctgaagagtcacccacatctcca
ccacctgaggcctctcgcctgtccccaccaactgaggagtcgcccctttctccaccacct
gagtcgtcacctttctctccactggaggggtgccctccatctcctgcactagacacaccc
ctgtctccaccgcctgaagcctcacccctatctccaccatttgaggagtctcctctgtcc
cctccaccagaggaactgccctcttctccgccacctgaagcatctcgcctatcccctcca
ccagaagagtcacccatgtcccctccacccgaagagtcacccatgtcccctccacctgag
gcatctcgtcttttcccaccatttgaagagtctcccctatctcctccacctgaggactct
cctctgtccccacctccagaggcatcacggctgtccccaccccctgaggactcccccatg
tctcccccacctgaagactcacctatgtcccccccacctgaggtgtcccgcttcttgccc
ctgcctgtcctgtcacatctgtcgcctctgcctgaggtatcacggctgtccccaccacct
gaggaatctcccctgtccccaccacccgaggactctcctgcctcacctccacctgaagcc
tcccgactgtccccaccacccgaggactctcctgcctcacctcctcctgaagcctcccga
ctgtcccgtccccgggaagactcacctgcttcaccaccaccagaggactcactcgtgtcc
ttgccgatggaggagtcaccgctgtcgccactgcctgaggagctgagactctgccctcag
cccgaggaaccatacttgtctcctcagcctgaggagccccgactctgtccccagcctgag
gagctgccgctgtccccacagtctgaggagccatgcctgtcccctgtgcttgtagaacca
ggcccgtcttctcagcctgaggagccacacctgtcccctgtgcctcaggagccacacctg
tcccctcagcctgaggagccacacctgtcccctcagcctcagcagttgcacctgtctcct
cattctgaggagccctgcctgtcccccatgcctgaggagccatgcctgtccccacagcct
gaggaactaaatggacctcctcagcctgcagagcctcctgaggaaccaagccagagctct
gcacctaaggagctgtccttgttttccccaagtggggaaccacctttaccccccatgctt
ggagagccagccctgtctgagcctggggaaccacctctatccccacttcccgaggagctg
cccttgtccctgtcgggggagccagtcttgtcacctcagctgatgccaccagatcctctt
cctcctccactctcacccattatcccagctgcagcccctccagccttgtctcctttgggg
gagttagagtacccctttggtgccaaaggggacagtgaccccgagtcaccgttggctgcc
cccatcctcgagacacctatcagccctccaccggaagccaactgcactgaccctgagcct
gtgcccccgatgatcctccccccatctccaggctcacccctgggacccgcctctccgatc
ctcatggagcgcctccctccaccttgctctccgctccttccgcactccttgcctcctccg
accccccctccttcccactgctcacctcctgctctgccgctctcagttccctccccgctg
agtcctgtgcagaaggcagtggatgtctcagatgaagctgagctgcacgagatggagact
gataaaggcccggaacctgagtgcccagccttggagcccagggccaccagtcccctgccg
tcccctctgggagacctttcttgccccgcccccagccctgccccggccctggatgacttc
tctggcttgggagaagacacagcccctctagatgggactggacagatgtctggcagcttg
gctggtgaacttaaaggttctcctgtgctcctggaccccgaggagctgacccctgtgacc
cctatggaggtctatggcccagaatgcaagcaggcagggcaaggctcaccctgtgaagag
caggaggagcctggtgcaccaatggcccccatgccgcccactctcatcaaatctgacatc
gtcaatgagatctctaacctgagccagggcgatgccagtgccagttttcctggttcagag
cctctgctgggctcccctgaccccgaggggggcggctccttgtccatggagctgggagta
tccacggatgttagtccggcccgagatgagggttccctacgcctctgcactgactctctg
ccagagacagacgactccctgctgtgtgacactgggacagcaaccagtggaggcaaagcc
gagggggacaaagggcggcggcgaagctcccccgcccggtcccgaatcaaacagggtcgg
agcagcagtttcccaggacgacgccggcctcgtggaggagcagcgcatggaggccgaggg
agaggacgggcccgactgaagtcgaccacttcttccgttgagacactggtggctgatatt
gatagttctcctagcaaggaggaggaggaggaagacgatgacaccatgcaaaataccgtg
gttctcttctctaacacagacaagtttgttctaatgcaggacatgtgtgtggtgtgcggc
agctttggccggggcgctgagggccacctcttggcctgttcacagtgttctcagtgctat
cacccgtactgtgtcaacagcaagatcaccaaggtgatgctgctgaagggctggcgttgt
gtggagtgtatcgtgtgtgaggtgtgcggccaggcctccgacccttcgcgcctgctgctc
tgtgatgactgtgacattagctaccatacatactgcctggatcccccactgctcactgtg
cccaagggtggctggaagtgcaagtggtgtgtgtcgtgtatgcagtgtggggccgcctcc
cctggcttccactgtgaatggcagaatagttacacacattgcgggccatgtgccagcctg
gtgacctgtcctgtctgtcatgctccctatgtggaggaagacctgctaatccagtgtcgc
cactgtgaacggtggatgcacgccggctgcgagagcctcttcacagaggatgaggtggag
caggccgccgacgagggctttgactgtgtttcctgccagccctatgtggtgaagcctgtg
gtgcccgtcgccccaccagagctggtacctgtgaaggtaaaagagccagagccccagttc
tttcgcttcgagggtgtgtggctgacagaaactggcatggcggtgctgcgtaacctgacc
atgtcaccactgcacaagcggcgccagcggcgaggacggctaggcctcccaggcgaggca
gggctggagggttctgagccctcagatgcccttggccctgatgacaagaaggatggggac
ctggacactgacgatctgctcaagggtgaaggcggtgttgagcaaatggaatgtgaaatt
aagctagaaggccccgccagccctgatgtagaacttggcaaagaagagacagaggaaagc
aaaaagcgcaagcgcaaaccctatcggccaggcattggtggtttcatggtacggcagcgg
aagtctcacacccgcgtgaaaagggggcctgctgcacaagcagaggtgttgagtggggat
ggacagcccgacgaggtgatgcctgctgacctgcctgcagagggctctgtggaacagagc
cttgctgagggggacgagaagaagaagcaacagcgacgagcgcgcaagaagagcaagctg
gaggacatgttccctgcttacctgcaggaagccttctttggaaaggacctgctggacctg
agtcggaaggccctgtttgcagttggggtgggccggccaggctttggactgggagcctca
aagccccgggccgatggaggttcggataggaaggagcttatgacggccatgcacaaagga
gatgatggcccggatgttgcagatgaggagtcccatgggcctgagggcacggctgattta
ccagggcttgaggatgggggtgtaaaggcatccccagtgcccagtgaccccgagaagccg
ggcaccccaggtgaaggagtgcttagctctgacttagacaggattcccacagaagaacta
cccaaaatggagtccaaggacctgcagcagctctttaaggatgtcctgggctcagaacga
gagcagcatttgggttgtgggactcctggtctagaaggtggccgaacatcactgcagagg
ccctttctccaaggcggcctcgctttgggcagtctcccctccagcagcccgatggactcc
tacccaggcctctgccagtcgcccttcttggattctagggagcgcgggggcttctttagc
ccagaacccggtgagccagacagcccttggacaggctcagggggcaccacaccctccacc
cccaccacgcctaccacagagggcgagggagacgggctgtcctataaccagcggagtctg
cagcgttgggaaaaagacgaggagctgggtcagctctccactatctcacctgttctctat
gccaacattaactttcctaatctcaagcaagattacccagactggtctagccgatgtaaa
caaatcatgaagctctggagaaaggttccagccgctgacaaagccccctacctgcaaaag
gccaaagataaccgggctgctcaccgcatcagcaaggtgcagaagcaggctgagagccag
atcagcaagcaagccaagatgggcgacatagcccgtaagactgatcgaccggccctccat
ctccgtattccctcccagccaggggcactgggcagtccgccccctgctgcggcccccacc
attttccttggcagccccaccacccctgctggcttgtctacctctgcggacgggttcctg
aagccaccagcgggcacagtacccggccctgactcacctggtgagctcttcctcaagctc
ccgccccaggtgcccgcccaagtgccttcgcaggacccctttggactggcccctgcctac
gccccggagccccgcttctctgcggcaccacccacttatcctccttacccaagccccact
ggagcccctgcccagcccccaatgctgggtaccacaactcgacctgggactggccagcca
ggggaatttcatactaccccaccgggtacccccagacaccagccttccacgcctgacccc
ttcctcaaacctcgctgcccctcattggacaacctggctgtgcctgagagcccaggggta
gcaggaggcaaggcttctgagcctctgctctcacccccaccttttggggagtcccggaag
tccctagaagtgaagaaggaagagcttggggcatcctctcctggctatggtcccccaaac
ctgggctgtgttgactcaccctctgctggcccccacctgggtggcctggagttaaaggca
cctgatgtcttcaaagcccccctaacccctcgggcatctcaggtagagccccagagcccg
ggcctgggcttgcgggcccaggagccaccccctgcccaggctttggccccttcacctccc
agccacccagatgtctttcgttctggcccataccccgacccctatgcccagcccccattg
actcctcggccccaaccaccaccccctgagagctgctgtgccccgcctccccgatcactg
ccctctgaccctttctccagagtgcccgctagtcctcagtcccagtccagttcccagtcc
ccactgaccccacgtcccctgtcggctgaggctttctgcccatcccctgtaacccctcgc
ttccagtcccctgacccttattctcgtccaccctcacgacctcagtcccgtgatcccttt
gccccattgcataagccaccccggccccagccccctgaagttgcctttaaggctgggccc
ctagcccacactccactgggagctgggggcttcccagcagccctgccctctggcccagca
ggtgagctccatgccaaggtcccaagtgggcagcccactaattttgcccgttctcccggg
acaggcacatttgtgggcaccccatctcccatgcggttcactttcccacagggggtaggg
gaaccttccctaaaaccccctgtccctcagcctggtctcccttcaccccatgggatcaac
agccattttgggcctggccccaccttgggcaagcctcaaagcacaaactacgcagtagcc
acggggaactttcacccatcaggcagccccctagggcccaacagtgggcccacaggggag
ggctatgggctgtccccactacgccccgcatccgttctgccacctcccgcacctgatgga
tccctcccctacttgacgcatggagcctcacaaagggtaggcatcacctctccagtggaa
aagagagaagacccaggagctacaatgagtagtagctctttggccacacctgaactctca
agtgcccaggatgcaggcatatctagcctcagccagacagagctggagaagcagcggcag
cgccagcgactacgggaactgctgattcgacagcagatccagcggaacaccctgcggcag
gagaaggaaacagctgcagcagctgcaggtgcagtagggcctccaggcaactggggtgct
gaacccagcagccctgcctttgaacagctgagccgaggccagacccctttcactgggtct
caggataggagcagcatcgtggggctacccgccagcaagctaggcggccccacgctgggc
ccaggggccttctccagcgatgatcggctcgcccggccacttccgccagccacaccttct
tccatggacatgaacagcaggcaacttgtcggaggctcccaggccttctaccagcgaaca
ccctatcctgggtccctgcccttacagcagcagcagcagcaacaacaacagcagcagcaa
caacagcagcagcagcagcaacaacagcagcagcagcagcaacaacaacaactgtggcag
cagcagcagcagcagcagcaacaacagcagcagcaggcggcggcagcagcagcagcaacc
tccatgagacttgccatgtctgctcggttcccgtcaactcctggacctgaacttggccgc
caagcactaggttcccccttggcaggaatccccacccgacttccaggccctgctgagcca
gttcctggtcccgctggccctgctcagttcatcgagttgcgacataatgtgcagaaagga
cttggacctggggtatctccgtttcctggtcaaggaccccctcagaggccccgtttttac
ccagtcagcgaggaactccatcgactggctcctgaaggtcttcggggcctggctgttcca
ggccttccctcacaaaagccttcagccctgccagcccccgagctgaacaacagcctccat
cagacgccccatgccaagggccccgccctagcctctggcttggagctggtcagccgccca
ccgtcaaacactgaacttagtcgtccccctctggccttggaggctgggaagttgccttgt
gaggaccctgagctggatgacgactttgatgcccacaaggccctggaggatgatgaagag
cttgctcacttgggtctgggtgtggatgtggccaagggtgatgatgagctgggcaccctg
gaaaacctggagacgaatgacccccacctggatgacctcctcaatggagatgaatttgac
ctgctagcgtacactgaccctgagcttgatactggggacaagaaggacatcttcaatgag
cacctaaggctggtggagtcagcaaatgagaaggctgagcgagaagccctgctgcggggg
gtggagccagtgtccttgggccccgaggagcggcctccacctgccccagataactctgag
cctcgcttaacatctgtgctccccgaggtgaagcccaaagtggaggagggaggacgccat
ccttctccttgccagttcaccattaatacccccaaggtggagccagcccctcctgccact
tccctcagcctgggtctgaagccaggacagactgtgatgggcacccgggacactcgagga
ggagtgggtacaggatcgttccccagcagtgggcacacggctgagaagggcccctttggg
gccacaggaggaacaccagctcacttgctgaaccccagctcactgagtggcccagctgca
tcctctcttctggaaaagtttgagctagaaagtggggccctaaccttacccagtgggcat
gcagcagctggggatgaactggacaaaatggagagctcattggtagctagcgagttgccc
cttctcattgaggacctactagagcacgagaagaaggagctacagaagaagcaacagctt
tcagcacagactgtgctgcctgcccagcagcagcagcagcagcagcagcagcagcagcag
cagcagcagcagcataccctccttcccacaccaggccctgcccaggcactgcctttgcca
catgagcctgggccaccacagcagcttgctctaggtattggaagtacccggcagccaggc
ttgggccagtcgatggtgcccatccagccaccagctcatgcccttcagcagcgcctggcc
ccatccgtggctatggtgtctaaccaagggcatatgctaagtgggcagcaagcagggcag
acaggcctggtaccccagcagagttcacagccagtgttggcacagaagcccatgagtgcc
atgccagcgtccatgtgcatgaagccccagcagctggcgatgcagcagcagcagctggcg
aatagtttcttcccagacacagacctagacaaatttgctgcagaagacatcattgatcct
attgcaaaggccaagatggtagctttgaaaggcattaagaaagtgatggctcagggcagc
attggtgtggcacctggtatgaacaggcagcaagtgtccctgctggcgcagaggctctcc
gggggctctggcagtgatcttcagaaccacgtggcacctgggagtggccaggaacggaat
gctggtgaccctgcccagcctcgtcctaacccgcccacttttgcccagggagtgatcaat
gaggctgaccagcggcagtatgaggagtggctgttccacacccagcagctcctacagatg
cagctgaaggtgttagaggagcagattggtgtgcaccgcaagtctcggaaggctctgtgt
gccaagcagcgcactgccaaaaaggccggccgcgagttccccgaagccgatgctgagaag
ctcaagctggtcactgagcagcagagcaagatccagaagcagctggatcaggtccggaaa
cagcagaaagagcacacaaatctcatggcagaatatcggaacaagcagcagcagcaacag
cagcagcagcagcagcagcagcagcagcagcactcagctgtgctggctgtcagcccttct
cagaatcctcgggtactcaccaagctccctggccagctgctccctgcccatgggttacag
ccaccgcaggcacctccgggtgggcaagctggtggtcttcgtctgcctccagggggtatg
gtactacctggacagtctggtggtccattcctcaatactaccttggcccaacagcagcaa
cagcagcattctggtgtggctggatccttgactggcccccctgggagcttcttccccggc
aatcttgctctccgaagccttggacctgactcgaggcttttacaggaaaggcaactacag
ctgcagcagcaacgaatgcagctggctcagaaactacagcagcagcagcaacaacaacaa
cagcaacaacaacagcaacacctcttagggcaggtggcaatccaacaacaacaaggtccc
ggagtacagaaccaggctctgggtcctaagcctcagggccttctgcctcccagcaaccac
cagggcctcctggtccagcagttgtccccccagcagtcccagggatcccagggcctgctt
ggccctgcccaggtgacagtgctgcagcagcagcagcagcaacagcagcactctggagct
ctgggtcctcagggccctcacagacaggtgcttatgactcagtccagggtgctgagctcc
cctcagctggcacagcagggtcacagccttatgggacaccggctactcacagcccagcag
cagcagcagcagcagcagcagcagcagcaacagcaacagcagcagcaacaacagcaacaa
caacaacagggatctatgacagggctttcccaacttcagcaaggaatgatgtcacatggt
ggacagcccaaaatgagtgctcaggccttgggttctttacagcagcagcagcaacagcta
cagcagcaacagatgctacagcagcaacagctccagcaacaacagcaacagctacaacag
cagcaacaacagcaacagctacaacagcaacaacagcaacagctgcagctacagcagcag
caacaacagcaacagcaacatctgcagcatcagcagcaacaacagcagcagttgcagcag
cagcaacagctgcagcagcaacaacagcagcagctgcacttgcagcagcagctgcaccag
caacaacagctgcagcttcagcaacagcagatgggcctcttgaaccagaatcgaacttta
ttatctccgcagcagcagcagcaacaacagcagcagcaacagcagcagcagcagcagcag
cagcagcagcagcagcagcagcagcaagtgacacttggccctggcctgccagtcaagcct
cttcaacacttttctagctctggagccctaggcccaaccctcctcctgacaggcaaggaa
caaaacaatgcagagacagcgcttccttcagaggtcactgagggaccttcaacacatcaa
ggagggccaccagcagtggggactgcacctgagccaatgtctgttgagccaggggaggtg
aagccttccatttctggagactcacagctcctccttgtccaatcccaggcccaatctcag
gccacctcagtgcagctgcagcccccgctcaggctcccaggacaaccccagccccaggtg
aacttgcttcacacagcaggtggaggaagccatgggcagcagctagggagtggatcctcc
tctgagtccccagctgtaccccacctgctggcccaaccctctgtttccttgggggagcag
cctggacctatggcccagaaccttctgggctcccaacagccccttgggctagatcgaccc
attcaaaataacacagggtcacagcctcccaaatcagggcctgctccgcagtctgggcag
ggtcctcctggagctggagtcatgcctacagtgggtcaacttcgagcacagctccaagga
gtcctggccaaaaacccacagctgcggcacctgagcccacagcagcagcagcagctgcag
gcactcctcatgcagcggcagctacagcagagtcaggcagtacgccagactccaccgttc
caggagcccgggacccagccctctcccctccagggtctcctgggctgccaacctcaacct
gggggtttttctgtatctcagacaggacccctccaggagctaggggcagggtctcgacct
cagggcccaccccggctccctgtcccacaaggagccttatctacaggaccagtgcttggc
cctgcccatcccacacctccaccttccagtccccaagagccaaagagaccttcacaatta
ccttcccccagtgcccagctaaccccaacccatccagggactccaaagccccaggggcca
gccttggagctgcctcctgggagggtctcacctgctgctgcccagcttgcagatactttc
tttggcaaggggctaggaccttgggacccctcagacaacctcacagaagcccaaaagccc
gagcagagcagcctggtacctgggcatttggatcaggtgaacggacaggtggtacatgag
ccgtcccagctcagcatcaagcaggagcctcgggaagagccgtgtgccctgggtgcacag
acagtgaaaagggaggccaatggtgagccggctggggcaccaggcaccagcaaccacctt
ctgctagcaggctcccgctcggaggctgggcatctgctcttgcagaagcttctacgggca
aagaatgtgcaacttggtgctgggcgggggcctgaggggcttcgagctgagatcaatgga
cacattgatagcaagctgtcagggctggagcagaaactacagggtacttccagcaacaaa
gaggatgcagccacaagaaagcctttgccagcgaagcctaagcgggtgcagaagacaagt
gacagattgccaagctcccgaaagaagctgcggaaagaagatggggtcagggccaatgag
gccttattgaaacagctaaaacaggaactgtcccagctgccgctgacggagcccaccatc
accgccaattttagcctctttgctccctttggcagtggctgcctagtcagcgggcagagc
cagctcaggggggcctttggaagtggggctctgcacaccggccctgactactactctcag
ctgcttaccaagaataacctgagtaacccgccgacaccaccctcgtcgctgccccccacc
ccacccccatcggtgcagcagaagatggtgaatggtgtcactccctccgacgagctgggg
gagcgccccaaggacacagcctctgcccaggacagtgaaggagcactgagggatgctgca
gaagtgaagagtttagacctgctggctgctctgcctacaccccctcacaatcagactgag
gatgtcagaatggagagtgacgaggacagcgattctcctgatagcattgtgccagcttcg
tcccctgagagcatccttggggaagaggccccgcgttttcctcagctgggatctggccga
tgggagcaagacaaccgggccctctcccccgtcatccctatcatccctcgcaccggcatc
cctgtcttcccagataccaaaccttacggggtccttgacctggaggtccctggaaagctg
cctgctacagcttgggagaagggcaagggaagtgaggtgtcagtcatgctcacagtctct
gccgccgccgccaagaacctgaacggtgtcatggtagcagtagctgagctgctaagcatg
aagatacccaactcgtatgaggtgctgttcccagatggccctgccagggcaggccttgag
cccaagaagggggaagctgaaggccctggtgggaaagaaaaaggattgagtggcaagggc
ccagacacaggacctgattggctaaagcagtttgatgcagtgttgcctggctacaccctc
aagagccagttagacatcttgagcctcttgaagcaggagagtcctgccccagagccatcc
atccagcacagctacacatacaatgtctccaacctggacgtgaggcagctctccgcccca
cctcctgaggaaccttccccacctccgtcccctttggcaccctctcctgccagccctccg
gctgagcccatggttgaacttcaggctgagaggcctgctgagccacccatcccttcacct
ctcccactggcctcatcccctgaatctgcccgccccaagccccgagcccgaccccctgaa
gagagcgaagattcccgccccccacgccttaaaaagtggaaaggggtacgctggaagcgg
ctgcggctcctgctgaccatccagaaggggagtggtcatcaagaggatgagcgggaggtg
gcagagtttatggagcagtttggtacagctttgagaccaagcaaggtgcctcgagataac
cgccgatgctgcttctgtcatgaagagggagatggtgccaccgatgggcccgcccgcctg
ctcaacctcgacttggacctctgggtacacctcaactgtgccctgtggtccacggaagtg
tatgagacccagggcggggcactgatgaatgtggaggttgccttgcaccgaggattgcta
accaagtgctccctgtgccagcgaactggtgccactagcagctgcaaccgcatgcgttgc
cccaatgtctaccattttgcctgtgccatccgcgctaagtgcatgttcttcaaggacaag
accatgctgtgtcccgtgcacaagatcaagggcccctgtgagcaggagctcagctcattt
gctgtcttccggagggtctacattgagcgggacgaggtgaagcagatcgctagcatcatc
cagcggggagagcggctacacatgttccgagtaggaggccttgtgttccatgccatcgga
cagctgctcccacaccagatggctgactttcacagtgccactgcactctatcctgtgggc
tatgaggccacgcgcatctactggagtcttcgtactaacaatcgtcgctgctgctaccgc
tgttccatcagtgagaacaatggacggcctgagtttgtgatcaaagtcattgaacagggt
ttagaggatctggtcttcaccgatgcgtctccccaagctgtgtggaaccgcatcattgag
cctgtggctgccatgagaaaagaagccgacatgctgagactcttccccgagtacctgaaa
ggcgaagaactctttgggctgacagtgcatgcagtgcttcgcatagctgaatcgctacct
ggggtggagagctgtcagaattatttattccgctacgggcgccaccctctgatggagtta
ccgctcatgatcaaccccaccggctgtgccagatcagaaccgaaaatcctcacacactat
aaacggccccataccttgaacagcaccagcatgtctaaggcgtatcagagcaccttcaca
ggcgagaccaacaccccgtacagcaagcagtttgtgcactccaagtcatctcagtaccgg
cgcctgcgcaccgagtggaagaacaatgtgtatctggctcgttcgcgtatccagggcctc
ggcctctatgcagccaaggacctggagaagcacacgatggtcatcgagtacatcggcacc
atcattcgcaatgaggtggccaatcggcgggagaaaatctatgaggagcagaaccgcggt
atttacatgtttcggataaacaacgagcatgtgattgacgccacgttgaccggaggccct
gccaggtacattaaccactcctgtgcccctaactgtgtagcggaggtcgtgacgtttgac
aaggaggacaaaattattatcatctccagccggcgaatccccaaaggagaggagctgacc
tatgactatcagtttgactttgaggacgatcagcacaagatcccctgtcactgtggagcc
tggaactgtaggaaatggatgaactaa

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