KEGG   Mus musculus (mouse): 381091
Entry
381091            CDS       T01002                                 

Gene name
H2-Eb2, A130038H09Rik, H-2Eb2, Ia-5, Ia5, Iebeta2
Definition
(RefSeq) histocompatibility 2, class II antigen E beta2
  KO
K06752  MHC class II antigen
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04145  Phagosome
mmu04514  Cell adhesion molecules
mmu04612  Antigen processing and presentation
mmu04640  Hematopoietic cell lineage
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04672  Intestinal immune network for IgA production
mmu04940  Type I diabetes mellitus
mmu05140  Leishmaniasis
mmu05145  Toxoplasmosis
mmu05150  Staphylococcus aureus infection
mmu05152  Tuberculosis
mmu05164  Influenza A
mmu05166  Human T-cell leukemia virus 1 infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05310  Asthma
mmu05320  Autoimmune thyroid disease
mmu05321  Inflammatory bowel disease
mmu05322  Systemic lupus erythematosus
mmu05323  Rheumatoid arthritis
mmu05330  Allograft rejection
mmu05332  Graft-versus-host disease
mmu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    381091 (H2-Eb2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    381091 (H2-Eb2)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    381091 (H2-Eb2)
   04612 Antigen processing and presentation
    381091 (H2-Eb2)
   04658 Th1 and Th2 cell differentiation
    381091 (H2-Eb2)
   04659 Th17 cell differentiation
    381091 (H2-Eb2)
   04672 Intestinal immune network for IgA production
    381091 (H2-Eb2)
 09160 Human Diseases
  09163 Immune disease
   05310 Asthma
    381091 (H2-Eb2)
   05322 Systemic lupus erythematosus
    381091 (H2-Eb2)
   05323 Rheumatoid arthritis
    381091 (H2-Eb2)
   05320 Autoimmune thyroid disease
    381091 (H2-Eb2)
   05321 Inflammatory bowel disease
    381091 (H2-Eb2)
   05330 Allograft rejection
    381091 (H2-Eb2)
   05332 Graft-versus-host disease
    381091 (H2-Eb2)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    381091 (H2-Eb2)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    381091 (H2-Eb2)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    381091 (H2-Eb2)
   05152 Tuberculosis
    381091 (H2-Eb2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    381091 (H2-Eb2)
   05164 Influenza A
    381091 (H2-Eb2)
   05168 Herpes simplex virus 1 infection
    381091 (H2-Eb2)
   05169 Epstein-Barr virus infection
    381091 (H2-Eb2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    381091 (H2-Eb2)
   05140 Leishmaniasis
    381091 (H2-Eb2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    381091 (H2-Eb2)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   381091 (H2-Eb2)
  Exosomal proteins of epithelial cells
   381091 (H2-Eb2)
  Exosomal proteins of breast milk
   381091 (H2-Eb2)
SSDB
Motif
Pfam: MHC_II_beta C1-set Ig_3 ig YtpI Tricorn_C1 DUF5668
Other DBs
NCBI-GeneID: 381091
NCBI-ProteinID: NP_001029150
MGI: 95902
Ensembl: ENSMUSG00000067341
Vega: OTTMUSG00000020169
UniProt: Q3UUV9
Position
17 B1; 17 17.98 cM
AA seq 287 aa
MVSLWLPRGLCVAAVILSLMMLTPPVILVRDPRPRFLEQLKAECHYFNGKERVWSVTRFI
YNQEEFARFNSDFGKFLAVTELGRPIVEYLNTQKDMLDNYRASVDRCRNNYDLVDIFMLN
LKAEPKVTVYPAKTQPLEHHNLLVCSVIDFYPGSIEVRWFRNGEEEKTGVVSTGLIQNRD
WTYQTLVMLEMVPRGGEVYTCQVEHPSLTSPVTVEWRARSTSAQNKLLSGVMGMALGLFI
LAVGLFFYLRNLRAGSVSHGAGEGAESFTSRLTGSGSECHMGPGLSI
NT seq 864 nt   +upstreamnt  +downstreamnt
atggtgtctctgtggctccccagaggcctctgtgtggcagctgtgatcctgagtctgatg
atgctgacccctccggtgattttagtcagggacccacgaccacgttttctggagcagttg
aaggctgagtgtcactacttcaatgggaaggagcgtgtgtggagtgtgaccagattcatc
tataaccaggaagagtttgcccgctttaacagtgactttgggaagttcctggcagtgact
gagctggggcggcccatagttgagtacttgaacacccagaaggacatgctggacaattat
cgtgcctcagtagacaggtgcagaaataactatgaccttgtggatatcttcatgttgaac
ttaaaagctgagcccaaggtgactgtgtaccctgcaaagacacagcctctggaacaccat
aacctcctggtctgctctgtgattgacttctaccctggcagcattgaagtcagatggttc
cggaatggcgaggaggagaagactggagttgtgtccactggactgatccaaaatagagac
tggacctaccagaccctggtgatgctggagatggttcctcggggtggagaggtttacacc
tgccaggtggagcatcccagcctgaccagccctgtcacagtggagtggagggctcggtcc
acatctgcacagaacaagttgttgagcggagtcatgggcatggcgctaggtctgttcatc
ctcgcagtggggctgttcttctatttaaggaatctgagagcaggatcagtgtctcatggt
gctggtgaaggagctgaaagtttcacatccagattgacaggcagtgggagtgaatgccac
atggggcctgggttgagcatctga

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