KEGG   Mus musculus (house mouse): 57257
Entry
57257             CDS       T01002                                 
Symbol
Vav3, A530094I06Rik, AA986410, Idd18.1
Name
(RefSeq) vav 3 oncogene
  KO
K05730  guanine nucleotide exchange factor VAV
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04015  Rap1 signaling pathway
mmu04024  cAMP signaling pathway
mmu04062  Chemokine signaling pathway
mmu04510  Focal adhesion
mmu04650  Natural killer cell mediated cytotoxicity
mmu04660  T cell receptor signaling pathway
mmu04662  B cell receptor signaling pathway
mmu04664  Fc epsilon RI signaling pathway
mmu04666  Fc gamma R-mediated phagocytosis
mmu04670  Leukocyte transendothelial migration
mmu04810  Regulation of actin cytoskeleton
mmu05135  Yersinia infection
mmu05205  Proteoglycans in cancer
mmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    57257 (Vav3)
   04024 cAMP signaling pathway
    57257 (Vav3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    57257 (Vav3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    57257 (Vav3)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    57257 (Vav3)
   04660 T cell receptor signaling pathway
    57257 (Vav3)
   04662 B cell receptor signaling pathway
    57257 (Vav3)
   04664 Fc epsilon RI signaling pathway
    57257 (Vav3)
   04666 Fc gamma R-mediated phagocytosis
    57257 (Vav3)
   04670 Leukocyte transendothelial migration
    57257 (Vav3)
   04062 Chemokine signaling pathway
    57257 (Vav3)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    57257 (Vav3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    57257 (Vav3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    57257 (Vav3)
SSDB
Motif
Pfam: RhoGEF SH3_2 CAMSAP_CH CH SH3_1 SH3_9 SH2 C1_1 PH CDC24 Filamin PH_10 C1_2 LZ3wCH Prok-RING_1 zf-RING_16 Spt5_N
Other DBs
NCBI-GeneID: 57257
NCBI-ProteinID: NP_065251
MGI: 1888518
Ensembl: ENSMUSG00000033721
UniProt: Q9R0C8
Position
3:109247757..109593010
AA seq 847 aa
MEPWKQCAQWLIHSKVLPPNHRVTWDSAQVFDLAQTLRDGVLLCQLLNNLRPHSINLKEI
NLRPQMSQFLCLKNIRTFLAACCDTFGMRKSELFEAFDLFDVRDFGKVIETLSRLSRTPI
ALATGIRPFPTEESINDEDIYKGLPDLIDETRVEDEEDLYDCVYGEDEGGEVYEDLMKAE
EAQQPKSQENDIRSCCLAEIRQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPD
LVKVHRSLMQEIHDSIVNKDDQNLYQVFINYKERLVIYGQYCSGVESAISNLDYISKTKE
DVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTHDPMEKANLKLALDA
MKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQER
HIFLFDLAVIVCKRKGDNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGL
EFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCRVCQMLLRGTFYQ
GYLCFKCGAKAHKECLGRVDNCGRVNSVEQGPFKPPEKRTNGLRRASRQVDPGLPKMQVI
RNYTGTPAPGLHEGPPLHIQAGDTVELLRGDAHSVFWQGRNLASGEVGFFPSDAVKPSPC
VPKPVDYSCQPWYAGPMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIK
ILTRDGFFHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEQPAGQRGNRT
GNSLLSPKVLGIAIARYDFCARDMRELSLLKGDMVKIYTKMSANGWWRGEVNGRVGWFPS
TYVEEDE
NT seq 2544 nt   +upstreamnt  +downstreamnt
atggagccgtggaagcagtgcgctcagtggctcatccacagcaaggtgctgccccccaac
catcgggtgacctgggactcggcgcaggtgttcgacctggcgcagacccttcgcgatgga
gtcctgctctgccagctgctcaacaacctgcggccacactccatcaatctgaaggagatc
aacctgaggccccagatgtcccagtttctctgtttgaagaacatccggacattcctggcc
gcctgctgcgatacctttggaatgaggaaaagtgaactttttgaggcatttgacctattt
gatgttcgagactttggaaaggttatagaaacattatctcggctatcccgaacaccaata
gcattggccacaggaatcaggccgttccccactgaagaaagtataaatgatgaagacatc
tacaaaggccttcccgacttaatagatgaaacccgcgtggaagatgaagaagacctctat
gactgtgtgtacggcgaggatgaaggcggagaagtctatgaagacttgatgaaggcggag
gaagcccagcaacctaaatcacaagaaaatgatatacggagttgttgcctagcagaaatt
aggcagacagaagaaaaatacacagaaacgttggagtcaatagaaaaatatttcatggca
ccattgaaaagatttctgacggcggcggaatttgattcagtatttattaacattcctgac
cttgtaaaagttcatcggagcttaatgcaagagattcatgattccattgtaaataaagat
gaccagaacttgtatcaagtttttattaactacaaggaaagattggttatttatgggcag
tactgcagtggagtggagtcagccatctctaacctagactacatctctaagacaaaagaa
gatgtcaaactgaaattagaggaatgttcaaaaagagccaataacgggaagtttactctg
cgcgatttgctggtcgttccaatgcagcgcgtgctgaagtatcacctcctccttcaggag
ctggtaaaacacacccatgaccctatggagaaggcgaacctgaagctggctctggatgca
atgaaggacttggcacaatatgtgaatgaagtaaaaagagataatgagacccttcgtgaa
attaagcagtttcagctatctatagagaatttgaaccagccagttttgctctttggacga
ccacagggagacggtgaaatccgaataaccactctggacaagcatacaaaacaagaaagg
catatcttcttattcgacttggcagtgattgtctgtaaaaggaaaggcgataactacgag
atgaaggaaataatagatctccagcagtacaagatagccaacaaccctaccactgacaaa
gagaataaaaagtggtcttatggcttctacctcatccatacccaaggacaaaatgggtta
gaattttattgcaaaacaaaagatttaaagaaaaaatggctggaacagtttgaaatggct
ctatccaacataaggccagactatgcagactccaatttccatgatttcaagatgcacacc
ttcactcgggtgacatcctgcagggtctgccagatgctcctgaggggaacattttatcaa
ggctacttatgttttaagtgtggagcaaaagcacataaagaatgtttgggaagagtagac
aattgtggcagagttaattccgttgaacaagggccattcaaaccaccagagaaacggacc
aatggacttcggagagcttccagacaggtggacccaggtttgccgaagatgcaggtcatt
aggaactacactggcaccccggccccagggcttcatgaaggaccaccattgcatatccag
gcaggcgacactgttgaacttctgagaggagatgcacacagtgtgttctggcagggacga
aacttagcttcaggagaggttggatttttcccaagtgatgctgtcaaaccctctccatgt
gtacctaaaccagtagattattcttgccaaccctggtatgctggcccaatggaaagattg
caggcagaaactgaacttattaacagggtgaatagtacttaccttgtaaggcacaggacc
aaagaatctggagaatatgcaattagcattaagtacaataatgaagcaaaacacatcaag
attttaacaagagatggcttttttcacattgcagaaaatagaaaatttaaaagcttaatg
gaacttgtggagtactacaagcaccattctctcaaagaagggttcaggaccttagataca
acgctacagtttccatacaaggagccagaacagccagctggacagaggggtaatagaaca
ggcaacagcttgttgagtcccaaagtactgggtattgccatcgctcggtacgacttctgt
gcaagagatatgcgggagctctccctattgaaaggagacatggtgaagatttacacgaag
atgagtgcaaatggctggtggagaggtgaagtaaatggcagggtgggctggtttccatcc
acatatgtggaagaagatgaataa

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