KEGG   Mus musculus (house mouse): 67603
Entry
67603             CDS       T01002                                 
Symbol
Dusp6, 1300019I03Rik, MKP-3, MKP3, PYST1
Name
(RefSeq) dual specificity phosphatase 6
  KO
K21946  dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu05202  Transcriptional misregulation in cancer
mmu05221  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    67603 (Dusp6)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    67603 (Dusp6)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    67603 (Dusp6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    67603 (Dusp6)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     67603 (Dusp6)
    3.1.3.48  protein-tyrosine-phosphatase
     67603 (Dusp6)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    67603 (Dusp6)
SSDB
Motif
Pfam: DSPc Rhodanese Tc-R-P PTP-SAK Y_phosphatase Init_tRNA_PT
Other DBs
NCBI-GeneID: 67603
NCBI-ProteinID: NP_080544
MGI: 1914853
Ensembl: ENSMUSG00000019960
UniProt: Q9DBB1
Position
10:99098676..99103351
AA seq 381 aa
MIDTLRPVPFASEMAICKTVSWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPTP
QLYFTTPSNQNVYQVDSLQST
NT seq 1146 nt   +upstreamnt  +downstreamnt
atgatagatacgctcagacccgtgcccttcgcgtcggaaatggcgatctgcaagacggtg
tcgtggctcaacgagcagctggagctgggcaacgaacggcttctgctgatggactgccga
ccacaggagctgtacgagtcgtcacacatcgaatctgccattaatgtggccatccccggc
atcatgctgcggcgtctgcagaagggcaacctgcccgtgcgtgcgctcttcacgcgctgc
gaggaccgggaccgctttaccaggcgctgcggcaccgacaccgtggtgctgtacgacgag
aatagcagcgactggaatgagaacactggtggagagtcggtcctcgggctgctgctcaag
aaactcaaagacgagggctgccgggcgttctacctggaaggtggcttcagtaagttccag
gccgagttcgccctgcactgcgagaccaatctagacggctcgtgcagcagcagttccccg
cctttgccagtgctggggctcgggggcctgcggatcagctcggactcttcctcggacatt
gagtctgaccttgaccgagaccccaatagtgcaacggactctgatggcagcccgctgtcc
aacagccagccttccttcccggtggagattttgcccttcctttacctgggctgtgccaag
gactcgaccaacttggacgtgttggaagagtttggcatcaagtacatcttgaatgtcacc
cccaatttgcccaatctgtttgagaatgcgggcgagttcaaatacaagcaaattcctatc
tcggatcactggagccaaaacctgtcccagtttttccctgaggccatttctttcatagat
gaagcccgaggcaaaaactgtggtgtcctggtgcattgcttggcaggtatcagccgctct
gtcaccgtgacagtggcgtacctcatgcagaagctcaacctgtccatgaacgatgcttac
gacattgttaagatgaagaagtccaacatctcccccaacttcaacttcatgggccagctg
cttgacttcgaaaggaccctgggactgagcagcccttgtgacaaccgtgtccccactccg
cagctgtacttcaccacgccctccaaccagaacgtctaccaggtggactccctgcagtct
acgtga

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