KEGG   Mus musculus (mouse): 68214Help
Entry
68214             CDS       T01002                                 

Gene name
Gsto2, 1700020F09Rik, 4930425C18Rik, GSTO_2-2
Definition
(RefSeq) glutathione S-transferase omega 2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00480  Glutathione metabolism
mmu00980  Metabolism of xenobiotics by cytochrome P450
mmu00982  Drug metabolism - cytochrome P450
mmu00983  Drug metabolism - other enzymes
mmu01100  Metabolic pathways
mmu01524  Platinum drug resistance
mmu05200  Pathways in cancer
mmu05204  Chemical carcinogenesis
mmu05225  Hepatocellular carcinoma
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    68214 (Gsto2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    68214 (Gsto2)
   00982 Drug metabolism - cytochrome P450
    68214 (Gsto2)
   00983 Drug metabolism - other enzymes
    68214 (Gsto2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    68214 (Gsto2)
   05204 Chemical carcinogenesis
    68214 (Gsto2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    68214 (Gsto2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    68214 (Gsto2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    68214 (Gsto2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mmu02000]
    68214 (Gsto2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     68214 (Gsto2)
Transporters [BR:mmu02000]
 Other transporters
  Pores ion channels [TC:1]
   68214 (Gsto2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N Glutaredoxin GST_C_2 GST_C_3 GST_C
Motif
Other DBs
NCBI-GeneID: 68214
NCBI-ProteinID: NP_080895
MGI: 1915464
Ensembl: ENSMUSG00000025069
Vega: OTTMUSG00000028267
UniProt: Q8K2Q2 Q9D2S1 Q8BW12
Position
19; 19 D1
AA seq 248 aa AA seqDB search
MSGDLSRCLGKGSCPPGPVPEGVIRIYSMRFCPYSHRARLVLKAKGIRHEVININLKSKP
DWYYTKHPFGQIPVLENSQCQLVYESVIACEYLDDVYPGRKLFPYDPYERARQKMLLELF
CKVPPLSKECLIALRCGRDCTDLKVALRQELCNMEEILEYQNTTFFGGDCISMIDYLVWP
WFERLDVYGLADCVNHTPMLRLWIASMKQDPAVCALHTDKSVFLGFLNLYFQNNPCAFDF
GLCNPIIR
NT seq 747 nt NT seq  +upstreamnt  +downstreamnt
atgtccggggatttgtcaagatgcttgggaaaaggaagctgtcccccagggccggtccct
gagggtgtgatccgaatctacagcatgaggttctgcccctactcgcacagggcacgcctg
gttctcaaggccaaaggcatcaggcatgaagtgatcaatattaacctgaaaagcaagcct
gactggtactatacaaagcatccttttggccaaattcctgtcttggagaacagccagtgt
cagctggtctatgaatctgtcattgcttgtgagtacctggatgacgtctacccgggaaga
aagctgtttccgtatgacccgtatgaacgagctcgccagaagatgttattggagctattc
tgtaaggtcccgcctttaagcaaggaatgtctgatagcgctgagatgcggaagagactgt
acggatctgaaggtcgccctgcgtcaggagttgtgcaacatggaagagattcttgaatat
cagaacactaccttcttcggcggagactgtatatccatgattgattacctcgtctggccc
tggtttgagcgcctggacgtatatggactggctgactgcgtgaatcacaccccgatgctg
cggctctggatagcctccatgaagcaggaccctgcagtgtgtgctctgcacactgataag
agcgtcttcctgggcttcttgaatctctatttccaaaacaacccttgtgcctttgatttt
gggctgtgtaacccaatcatacgataa

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