KEGG T01002: 74018

Mus musculus (house mouse): 74018

Entry

74018             CDS       T01002

Symbol

Als2, 3222402C23Rik, 9430073A21Rik, Als2cr6, Alsin, mKIAA1563

Name

(RefSeq) alsin Rho guanine nucleotide exchange factor

K04575

amyotrophic lateral sclerosis 2 protein

Organism

mmu Mus musculus (house mouse)

Pathway

mmu05014

Amyotrophic lateral sclerosis

mmu05022

Pathways of neurodegeneration - multiple diseases

Brite

KEGG Orthology (KO) [BR:mmu00001]
09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    74018 (Als2)
   05022 Pathways of neurodegeneration - multiple diseases
    74018 (Als2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    74018 (Als2)
Chromosome and associated proteins [BR:mmu03036]
Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    74018 (Als2)

SSDB

Motif

Pfam:

RCC1 RCC1_2 MORN VPS9 RhoGEF PH DUF2973

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

MGI:

Ensembl:

UniProt:

Position

1:complement(59201915..59276390)

AA seq 1651 aa
MDSKKKSSTEAEGSKERGLVHVWQAGSFSLTPERLPGWGGKTVLQAALGVRHGVLLTEDG
EVYSFGTLPWKSESAEICPSSPLLESALVGHHVITVATGSFHSGAVTESGVVYMWGENAA
GQCAVANQQYVPEPSPVSISDSETSPSLAVRILQLACGEEHTLALSLSREIWAWGTGCQL
GLITTTFPVTKPQKVEHLAGRVVLQVACGAFHSLALVQCLPPQDLKPVPERCNQCSQLLI
TMTDKEDHVIISDSHCCPLGVTLSESQAEKHASPAPSPHPEALDEQGEVFENTVVEAELN
MGSSQTTSGSAISTQQNVVGTAEVSSARTAPSYPDTHAVTAYLQKLSEHSMRENHEPGEK
PPQVQPLVEEAVPDLHSPPTTSTSALNSLVVSCASAVGVRVAATYEAGALSLKKVMNFYS
TAPCETAAQSGSASTGPESLKDLREEQVKQESLQGKKSSSLMDIREEELEGGSRRLSLPG
LLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLGHGDVLP
RLQPLCVKCLDGKEVIHLEAGGSHSLALTAKSQVYSWGSNTFGQLGHSEFPTTVPRLSKV
SSENGVWSVAAGQDYSLFLVDTEDFQPGLYYSGRQDRAEGDTLPENPSGTKTPVLLSCSK
LGYISRVTAGKDSYLALVDKNIMGYIASLHELASTERRFYSKLSEIKSQILRPLLSLENL
GTVTTVQLLQEVASRFSKLCYLIGQHGASLSSYLQGMKEASSLVIMKHSSLFLDSYTEYC
TSVSNFLVMGGFQLLAKPAIDFLNKNQELLQDLSEVNDENTQLMEILNMLFFLPIRRLHN
YAKVLLKLATCFEVTSPEYQKLQDSSSCYESLALHLGKKRKEAEYTLSFWKTFPGKMTDS
LRKPERRLLCESSNRALSLQHAGRFSVNWFILFNDALVHAQFSTHHVFPLATLWAEPLSE
EAGSVNGLKITTPEEQFTLISSTPQEKTKWLRAISQAVDQALRGTSDFPLYGGGSSVQRQ
EPPISRSAKYTFYKDTRLKDATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGE
YRIPNKALNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSS
SPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNK
MMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPHGDYIEGYFSGEWGSGIKITGTYFKP
SLYESDKDKPKAFRKLGNLAVAADEKWRAVFEECWRQLGCESPGQGEVWKAWDNIAVALT
TNRRQHKDSPEILSRSQTQTLESLEYIPQHIGAFSVEKYDDIKKYLIKACDTPLHPLGRL
VETLVAVYRMTYVGVGANRRLLQEAVKEIKSYLKRIFQLVRFLFPELPEEGSTIPLSAPL
PTGRRSFCTGKSDSRSESPEPGYVVTSSGLLLPVLLPRLYPPLFMLYALDNDREEDIYWE
CVLRLNKQPDIALLGFLGVQKKFWPATLSILGESKKVLSTTKDACFASAVECLQQISTTF
TPSDKLKVIQQTFEEISQSVLASLQEDFLWSMDDLFPVFLYVVLRARIRNLGSEVHLIED
LMDPFLQHGEQGIMFTTLKACYFQIQREKLN

NT seq 4956 nt +upstreamnt +downstreamnt
atggactcaaagaagaaaagctcaacagaggcagaaggatccaaagaaagaggcctagtc
catgtctggcaggcaggatccttttctctaacaccagagaggttgccaggctggggtgga
aagacagttcttcaggcagcccttggtgtgaggcatggagttcttctgactgaagatggt
gaggtctacagctttgggactcttccctggaaaagtgaatcagcagaaatttgtccaagc
agcccccttctagaaagtgccctggttgggcatcatgttattactgtggcaacagggagc
ttccacagtggagcagtgacagagagcggggtggtgtacatgtggggagagaatgctgcc
gggcagtgtgcggtagctaaccagcagtatgtgccggagccgagtcctgtcagcatttct
gactcggagaccagcccgtcattagcagttaggattctgcaattggcatgtggcgaggaa
cacacactggcattgtcactcagcagagagatctgggcatggggcaccggctgtcagctg
ggcctcatcaccaccactttcccagtgacaaagccacagaaggtggaacaccttgctgga
cgcgtggtgctccaggtggcctgcggtgcattccacagccttgcacttgtgcagtgcctc
cctcctcaggatctgaagccagtcccagagagatgcaatcagtgcagccagctgctcatc
accatgacagacaaagaggaccatgtgataatatcggacagccattgctgccctttaggt
gtgacattgtccgagtctcaagcagaaaagcatgccagccctgctcccagccctcaccca
gaggcactggatgagcagggagaggtgtttgagaacacggtggtagaagctgaactgaac
atgggaagcagtcagaccacaagtggcagtgccatttccacccagcagaacgtcgtggga
acagctgaagtgtcttctgccagaacagctccgtcatacccagacacccatgcggtaact
gcatacctgcagaagctgtcagagcattcgatgagggagaaccatgagcctggagaaaag
ccaccccaggtccagcctcttgtagaagaagcagttcctgatcttcacagtccaccaacc
acaagcacctcagccctcaacagcttggtggtctcctgtgcatctgctgttggtgtcaga
gtggctgccacctatgaagctggggccttgtctctcaagaaagttatgaacttttacagc
actgccccctgcgagacggcagctcagtcgggcagtgcctccacaggcccagaaagtctg
aaagatctccgagaagagcaggtgaaacaggagtcactgcaagggaagaaaagctcaagt
ctcatggacatcagagaggaggagttggagggagggagtcgaagactctccctcccaggg
ttgttgtcgcaagtttcccccaggctcttaaggaaggctgcgagggtgaaaactcggaca
gtggttctgactcccacatacagtggagaagcagatgcccttctgccttccctgaggaca
gaggtgtggacctgggggaaaggcaaggaagggcagctagggcacggcgacgtcctgccc
aggcttcagccgttgtgtgtcaagtgtctggatggtaaagaggtaatccacctggaggcg
ggcggctcccactccctcgcactcactgcgaaatctcaggtttactcatggggcagtaat
acctttggtcagcttgggcattctgagtttccaacaacggttcctcgactctcaaaggtt
agcagtgaaaatggagtctggagtgtagctgcaggccaagattattccttgtttttagtg
gacacggaagacttccagcctgggttgtattacagtggccgacaggaccgtgcagaaggt
gataccctgccagagaatcccagtggtacaaagactccagtacttctctcctgtagtaag
cttggatacataagcagagtaacagcaggaaaagatagctatctagccttggtggataag
aacatcatgggatacatcgccagtctccatgagttggcttctacagaaagacggttttac
tcaaaactgagcgaaatcaaatcacagatacttaggcctcttctcagtttagaaaatttg
ggcacagtgaccactgtccagctgttgcaggaagttgccagccggttcagcaagttgtgt
tacctcattgggcagcatggagcctcactaagcagctacctacagggcatgaaggaagcc
agcagcctggtcatcatgaagcactcaagtcttttcctggacagctacacagagtactgc
acatcagtttcaaatttcctggttatgggaggattccagcttcttgctaagcctgccatt
gatttcctaaataaaaaccaagaactcttgcaagatttgtcagaagtgaatgatgagaac
actcagttgatggaaatcctgaacatgctgtttttcttgccaatcagacgacttcataat
tatgcaaaagttttgctaaagcttgccacttgctttgaagtgacatctccagagtatcaa
aagctgcaggattccagttcttgctatgagtctcttgctctccatcttggcaagaagagg
aaggaagcagagtacacactgagcttctggaagacctttcctgggaaaatgacggattcc
ttgaggaagccagagcgccggctgctgtgtgagagcagtaaccgagccctctccctgcag
catgccggcaggttttctgtgaattggttcattctcttcaatgatgccctggtccatgct
cagttctctacacaccacgtgttccctttggccacactctgggcagagccactttctgaa
gaagctggtagcgtgaatggcttaaagataactacacctgaagaacaattcacactcatt
tcttcaacaccccaggaaaagaccaagtggcttcgggctatcagccaagctgtggatcag
gctttgagggggacgtccgatttcccactttacggaggcggcagcagtgttcagagacag
gaaccacccatctcaagaagtgccaaatacactttctacaaggatactcgcctaaaggat
gccacttacgatgggcgctggctttcagggaagcctcatggcaggggtgttctgaagtgg
cctgatggaaagatgtactctggcatgttcaggaatggcttggaagatggatatggtgaa
tacagaatccctaacaaggccctgaacaaagaagaccattatgtaggccattggaaagag
gggaaaatgtgtgggcaaggagtctacagctatgcctctggtgaagtgtttgaaggctgc
tttcaagataacatgcgccatgggcatggtctgctccggagtggaaaactgacttcttct
tctcctagcatgttcattggccagtgggtaatggataagaaagcaggatatggcgtcttt
gatgatatcaccaggggagaaaagtacatgggaatgtggcaggatgatgtgtgccaaggg
aatggggtagtagtcacccagtttgggttatactacgaaggcaacttccacctgaataag
atgatgggaaatggggttttgctttctgaagatgataccatctatgaaggagaattttcc
gatgactggacacttagtggaaagggaacgctgactatgccacatggagattatattgaa
ggttattttagtggagaatggggatctgggataaaaatcactgggacctacttcaaacct
agcctgtatgagagcgataaggacaagcccaaagccttcaggaagctggggaacctggcc
gtggcagcagacgagaaatggagagcagtgtttgaagaatgctggcgccagctgggctgt
gagagcccaggccaaggggaggtttggaaagcatgggataatattgctgtggccttgacc
acgaaccgtcgccagcataaagacagtccagaaatactaagccgctctcagactcagacc
ctggagagtttggagtacattccccagcacattggcgccttctctgtggagaaatatgat
gacatcaagaagtatttaataaaggcctgtgatactcctctgcacccactgggcaggctt
gtggagaccctggttgcggtgtatagaatgacatatgtgggtgtaggggccaaccgccgg
ttactgcaggaagctgtgaaggagattaaatcttatctcaagaggattttccagcttgtg
aggttcttgtttcctgagcttcctgaggagggcagcacaattcctctttctgctcctctg
cccactggaaggagatccttctgtactggaaaatcggattccagatccgagtcaccagaa
ccaggttatgtagtaacaagttctggcttactgcttccggtgctgctgccacggctctac
ccacctctcttcatgctctatgccctggataatgaccgagaggaagacatttactgggaa
tgtgtgcttcgactaaacaagcagccagatattgctctcttgggcttccttggagtacag
aaaaaattctggccagccaccttgtcaatccttggagagagtaaaaaggtgttgtcaacc
acaaaggatgcttgctttgcatctgcagtagaatgcctgcagcagatcagcacaacattt
actccatcagacaagcttaaagtgatccagcagacctttgaagagatctcccagagtgtc
cttgcatcgctgcaggaggacttcctctggtccatggatgacttgttccccgtcttctta
tacgtggtgctgcgggccaggattcggaacttgggctctgaagttcacctcattgaggat
ctgatggacccctttctccagcatggggaacaaggcatcatgttcaccaccttgaaggcc
tgttacttccagattcagcgggagaagcttaactag

All links

Gene (25)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (31)   
   RefSeq(nuc) (3)   
   GenBank (14)   
   EMBL (14)   
Protein domain (7)   
   Pfam (7)   
All databases (68)   

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