KEGG   Mus musculus (house mouse): 84505
Entry
84505             CDS       T01002                                 
Symbol
Setdb1, ESET, KMT1E, mKIAA0067
Name
(RefSeq) SET domain, bifurcated 1
  KO
K11421  [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00310  Lysine degradation
mmu01100  Metabolic pathways
mmu04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    84505 (Setdb1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    84505 (Setdb1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    84505 (Setdb1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.366  [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase
     84505 (Setdb1)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     84505 (Setdb1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    84505 (Setdb1)
SSDB
Motif
Pfam: DUF5604 Tudor_4 MBD Tudor_5 SET Pre-SET Chromo_MORC2_6th DUF4537 53-BP1_Tudor
Other DBs
NCBI-GeneID: 84505
NCBI-ProteinID: NP_001157113
MGI: 1934229
Ensembl: ENSMUSG00000015697
UniProt: D3YYC3
Position
3:complement(95230836..95264513)
AA seq 1308 aa
MSSLPGCMSLAAAPAAADSAEIAELQQAVVEELGISMEELRQYIDEELEKMDCIQQRKKQ
LAELETWVLQKESEVAYVDRLFDDASREVTNCESLVKDFYSKLGLQYHDSSSEDEASRPT
EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
HKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGKKYKVKFDNKGKS
LLSGNHIAYDYHPPADKLFVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
YASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEG
TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTR
PNMGAVRSKGPVVQYTQDLTGTGIQFKPMEPLQPIAPPAPLPIPPLSPQAADTESLESQL
AQSRKQVAKKSTSFRPGSVGSGHSSPTSSTLSENVSAGKLGINQTYRSPLASVTSTPASA
APPVPPVPPGPPTPPGPPAPPGPLAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTC
LSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIE
RYLFETGCDFLFLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPP
PQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPN
SGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDD
IAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPTSSDSSG
VDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENELSEM
TSKDSRPPDLGPPHVPIPSSVSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRS
SFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDNKQPKKEDPENRNKMPVVTEGSQNHG
HNPPMKSEGLRRSASKMSVLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTAGHT
SATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMA
SVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLR
FPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
NT seq 3927 nt   +upstreamnt  +downstreamnt
atgtcctccctccctgggtgcatgagtttggctgcagcgccagctgcagctgactctgca
gagattgctgagctgcagcaggcggtggttgaagagctgggtatctctatggaggaactt
cgtcagtacattgatgaggaactggaaaagatggactgcatacagcagcgcaagaagcag
ctcgcagagctggagacgtgggtactacagaaagagtctgaagtggcttatgttgatcgg
ctgtttgatgatgcatccagggaagtgactaactgtgagtctttggtgaaggatttctac
tctaagctgggactacagtatcatgacagtagctctgaggatgaagcttcccggcccaca
gagatcattgagattcctgatgaagatgatgatgtcctcagtattgattcaggtgatgct
gggagcagaactccaaaagaccagaagcttcgtgaagctatggctgccttaagaaaatca
gctcaagatgtccagaagttcatggatgctgtcaacaagaaaagcagttctcaagatcta
cataaaggaaccttgggtcaggtgtctggagaactgagcaaagatggggacctgatagtc
agcatgcggattctgggcaagaagaggactaagacatggcacaaaggcacccttattgcc
atccagactgttgggctaggaaaaaaatacaaagtgaaatttgacaacaaaggaaagagt
ctgctatctgggaaccatattgcctatgattaccaccctcccgctgacaagctgtttgtg
ggcagtcgagtggtggccaagtacaaagatggaaatcaggtctggctttatgctggcatt
gtagctgagacccctaacgtcaagaacaagctcagatttttaattttttttgatgatggc
tatgcttcctatgtcactcagtcagagctttatcccatttgccgaccactaaaaaagact
tgggaggacatagaagatagctcctgccgagacttcatagaggaatatatcactgcctat
ccaaaccgcccaatggtacttctcaagagtgggcagcttatcaagactgagtgggaaggc
acatggtggaagtctcgagttgaagaggtggatggcagcctagtcaggatcctctttctg
gatgacaaaagatgtgagtggatatatcgaggctctacacgcctggaacctatgtttagt
atgaagacatcctcagcctctgcaatggagaagaagcaaggggggcaactcagaacccgt
cctaatatgggtgctgtgaggagcaaaggtcctgttgttcagtatacacaggatctaact
ggtactggaatccagtttaagcccatggagcccctacagcctatagctccaccggcccca
cttcctatacctcctctttccccccaagcagctgacactgaaagcttagaaagccaactt
gcacaatcacggaaacaagtagccaagaagagcacatcattccgaccaggatctgtgggc
tccggccattcctcccctacttcatccacactcagtgaaaatgtgtctgctgggaaactt
gggataaaccagacatatcggtcacctttggcctcagtaacatctaccccagcatctgca
gcccctccagtccctccagtcccaccagggcctccaacccctccagggcctccagctcct
ccagggcctctagctcctccagccttccatggcatgttagagcgggcaccagctgagccc
tcctaccgagcccccatggagaagcttttctatttacctcatgtctgcagttacacttgt
ttgtcccggatcagacccatgagaaacgaacagtatcggggcaagaaccctctattagtt
ccacttctgtatgacttccggaggatgacagcacggcgcagagttaaccgcaaaatgggc
tttcatgtaatctataagacaccctgtggtctctgccttcggacgatgcaggagatagag
cgctacctttttgagactggctgtgactttctgttcctggagatgttctgtttggatcca
tatgttcttgttgacagaaagtttcaaccctttaagcctttttactatattttggacatc
acctatggcaaggaagatgttcccctgtcctgtgttaatgagattgacacaactccccca
ccccaggtggcctacagcaaggaacgcattcctggcaagggtgttttcattaacacaggc
cctgaatttctggttggctgtgactgcaaggatgggtgtcgggataaatccaaatgtgcc
tgccaccagctaactatccaggccacagcctgtaccccagggggccaagtcaaccctaac
tctggctaccagtataaaagactagaagagtgtctgcccacaggggtttatgagtgtaac
aaacgctgcaattgtgacccaaacatgtgcacaaatcggttggtgcagcatggtctgcag
gttcgactacagctgtttaagacacagaacaagggctggggtatccgctgcttggatgat
attgccaaaggctcttttgtctgcatttatgcaggcaaaatcctgacagatgactttgca
gacaaagaaggcctggagatgggtgatgagtactttgcaaatctggaccacattgaaagt
gtggagaacttcaaggaaggatatgagagtgatgtccccacttcctctgacagcagtggg
gtagatatgaaggaccaggaagatggcaacagcggttcagaggaccctgaagaatccaat
gatgacagctctgatgataacttctgtaaggatgaggacttcagcaccagttcagtgtgg
cgtagctatgctacccggaggcagactcggggtcaaaaggagaatgaattgtctgagatg
acttccaaggactcccgccccccagacctcgggcctccacatgttcctatcccttcctca
gtatctgtagggggctgcaatccaccttcctctgaagagacacccaagaacaaggtggcc
tcgtggttgagttgcaatagtgtcagtgaaggtggatttgctgactctgacagccgttct
tccttcaagactagtgaaggtggagatggccgtgctgggggaggccggggagaggctgaa
agggcctctacctcaggattgagcttcaaggatgaaggagacaataagcagcctaaaaaa
gaggaccctgagaaccgaaacaagatgccagtagttactgaaggctctcagaatcatgga
cataatcctcccatgaagtctgaagggcttcgccgatcagctagtaaaatgtctgtgctc
cagagccagcgagttgtgacttctactcagtcaaaccctgatgacatcctgacactgtcc
agcagcacagagagtgagggggaaagtggaaccagccgaaagcccactgctggtcacact
tcagccacagctgttgatagtgatgacatccagaccatctcttctggctctgacggtgat
gactttgaggacaagaagaacttgtcaggaccaacaaagcgccaggtggcagtaaaatca
acccgaggctttgctcttaaatcaacccatggtattgccattaaatcaaccaacatggct
tccgtggacaagggggagagtgcaccagttcgtaagaacacacgccagttctatgatggt
gaagagtcttgctacatcattgatgccaaacttgaaggcaacctaggccgctacctcaat
cacagttgcagccccaacctgtttgtccagaatgtgtttgtggatacccatgatcttcgc
ttcccttgggtggccttctttgccagcaagagaatccgggctggaacagaactcacttgg
gactacaactacgaagtgggcagtgtggaaggcaaggagctgctgtgctgctgtggggcc
attgaatgcagagggagacttctttag

  All links  
Gene (37)   
   RefGene (30)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (32)   
   RefSeq(nuc) (4)   
   GenBank (14)   
   EMBL (14)   
Protein domain (9)   
   Pfam (9)   
All databases (83)   

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