KEGG   Miniopterus natalensis (Natal long-fingered bat): 107534598
Entry
107534598         CDS       T05883                                 
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
  KO
K11427  [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
Organism
mna  Miniopterus natalensis (Natal long-fingered bat)
Pathway
mna00310  Lysine degradation
mna01100  Metabolic pathways
mna05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:mna00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    107534598 (DOT1L)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    107534598 (DOT1L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mna03036]
    107534598 (DOT1L)
Enzymes [BR:mna01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.360  [histone H3]-lysine79 N-trimethyltransferase
     107534598 (DOT1L)
Chromosome and associated proteins [BR:mna03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     107534598 (DOT1L)
   HMT complexes
    Dot1-containing complex
     107534598 (DOT1L)
SSDB
Motif
Pfam: DOT1 HALZ
Other DBs
NCBI-GeneID: 107534598
NCBI-ProteinID: XP_016065234
Position
Unknown
AA seq 1480 aa
MENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQV
YNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVA
AATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIAN
TSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVV
ELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTT
TPTKVPESKVAMPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRP
KKMSTANPERKPKKNPTALDLLHAQTVSQTAAPSPQDAYKSPHSPFYQLPPSVQRHPPDQ
LLLAPTPPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFG
HCQAQKEEIKRLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRS
QSLQLLKARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQ
ELLQLKSCVPPDDAVSLHLRGKGGLGRELEAEPSRLHLELDCSKFSLPHFSSMSPELSMN
GHVAGYELCNTLSRPSSKQNTPQYLASPLDQEVVPSTPSHSSRSRLEKLSGLALPDYTRL
SPAKLVLRRHLSQDHTKTSVGELHPRAEHAKENGLPYQSPGLTNGIKLSPQDPRPSSPVA
LQMTGEKGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPNRAEKR
STPSPVPQTRESSSTLEKQMGANAHGAGSNAAGSKSLTLAPTGFSYAGSVAISGALAGSP
APLAPGVEPPAFDESSSSGSLFTTMGSRSSTPQHPQLLGQPRNSSSASPTHQLCVSPRLS
STQGLLPDASKGDLPSEAGFSDPESEAKRRIIFTISAGAGSAKQSPSNKHSPLPGGTRGD
SSQSHGQDSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNI
NQPLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEEE
QGSTRIERKIATISLESKSPPKTLENGGSLVGRKPIPSSEPINSSKWKSTFSPIADLSLA
KAADSPLQASSALSQNSLFTFRPTLEELGSVDAKLAAHPRKSFPGSLSGAGGLSPISNPP
NGFTFSGSLAADLSLHSFSDGASLSHKAPEVASLGAPLSFSAPRGKEGSAEPCPFVNKRQ
LDGLGGPKGEGVKGREAEVSLPVCTPSDKASSHGKVGKSRDREPDFKNGHNLFISAAAVP
PGGLLSSPGLTTAVSSAGGTAPSSQTHRPFLGTFTPGPQFALGSMSLQANLGSSVLQSLF
SSVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGN
NT seq 4443 nt   +upstreamnt  +downstreamnt
atggagaattatgtcctaatcgactacgacaccaaaagctttgaaagcatgcagaggctc
tgtgacaagtacaaccgggccattgacagcatccaccagttgtggaagggaaccacacag
cccatgaagctgaacacgcggccatccaatgggctcctgcggcacatcctgcagcaggtt
tacaaccactcagtgacagaccctgagaaactcaacaactacgagcccttctccccggag
gtatacggggagacctcctttgacctggtcgcacagatgattgacgagatcaagatgacg
gaggacgacctgttcgtggacctgggaagtggagtgggccaggtcgtgctacaggttgct
gcggccaccaactgcaaacatcactacggagtcgagaaagctgatatcccagccaagtac
gcggagaccatggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgca
gaatacacactggaaagaggtgatttcctctcagaggagtggagagagcggatcgctaac
acaagtgttatatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaag
gagcgatttgcaaacatgaaggaaggtggcagaattgtgtcctcgaagccctttgcacct
ctgaacttcagaataaacagtagaaacttgagtgacattggcaccatcatgcgcgtcgtg
gagctctcgcccctgaagggctcagtgtcatggacggggaagcctgtctcctactacctg
cacaccatcgatcgcaccatacttgaaaactatttttctagtctgaaaaatccaaaactc
agggaggaacaagaggcagctcggcgccggcagcagcgagaaaataagagtaatacgact
acccccacgaaggtgcccgaaagcaaggtggctatgcctgcagacacctctgttgattct
ggtgctgaggaagagaaagcagcgactaccgctatcaagaagccttccccctccaaggcg
cggaagaagaagctgaacaagaagggccggaagctggctggccggaagcgtggacgtccc
aagaagatgagcactgcgaaccctgagcgtaagcccaagaagaaccctactgcactggac
ctgctgcatgcccagactgtgtcccagacagcagcaccctcaccgcaagatgcatacaag
tcacctcacagccccttttatcagctacctcccagcgtgcagcggcacccccctgaccag
ctgttgctggcacccaccccacccgcactgcagaagctgctagagtccttcaagattcag
taccttcagttcctggcgtacacgaagacccctcagtataaggccagcctacagcagctg
ctggaccaggagaaggagaagaatgcccggttgctgggtgctgcacaacagctgtttggt
cactgccaggcccaaaaagaagaaataaagaggctcttccagcagaaactggatgagttg
ggagtaaaggcactgacctacagtgacctgatccaagcacagaaagagatctcagctcac
aaccagcagctgcgagagcagacagagcagctggagaaggacaacagggaactgagaagc
cagagcctgcaactgctgaaggctaggtgtgaggagctgaagctagactggtccacactg
tccctggagaacctgctgaaggagaagcaggcactgaagagccagatatctgagaaacag
aggcactgcctggaactgcagatcagcatcgtggagctggaaaagagccagcgacagcag
gagctcctgcagctcaagtcctgtgtgccacctgatgacgctgtgtccctgcacctgcga
gggaaaggtggcctgggccgggaactggaggcagagcccagccggctgcacctcgagctg
gactgctccaagttctcactgccccacttcagtagcatgagcccagagctctccatgaat
ggccacgtggcaggctacgagctctgcaacacgctgagtcggccctcatccaagcagaac
accccccagtacctggcctccccgctggaccaggaggttgtgccaagtacccccagccac
agcagccggtcccggcttgaaaagctgtctggcttggccttgccagactacaccaggctc
tccccagccaagctggtgctaagacgccacctgagccaggaccacactaagacatccgtt
ggcgagctacacccacgagctgagcacgccaaggagaatggccttccataccagagccca
ggcctcaccaacggcatcaagctgagtcctcaggacccacggccatcatcccctgtggcc
ttacagatgacaggagaaaaaggcagtgagaagggtctgaaggagcgcgcctatgccagc
agcggggaggccatcaccagcctaccagtcagcataccgcttagcactgtgcagccgagc
aagctgcccgtcagcatccccctggccagcgtggtgttacccaaccgtgccgagaagaga
agcacccccagccctgtgcctcagacccgagagtcctcgtccacacttgaaaagcagatg
ggtgctaatgcccatggtgctgggagcaacgctgctgggagcaaaagcctcaccctggcg
cccacaggcttttcctatgcaggctcagtggccatcagtggggccctggcaggcagccca
gctccactcgctcctggagttgagccccctgcctttgatgagtcctccagctcggggagc
ctcttcaccaccatgggctcccgaagctccaccccgcagcatcctcaactgctagggcag
ccccggaactccagttcggcctcgcccactcatcagctctgcgtcagcccccggctcagc
tctacccagggcctgctccctgatgccagcaaaggggaccttccctctgaggctggcttc
tcagatccagagagcgaagccaagaggaggattattttcaccatctcggctggtgccggc
agtgccaaacagtcaccttccaacaagcacagccctctgcctgggggcacccgtggagac
agcagtcagagccatgggcaggacagcagaaagcgaggcaggaggaagcgggcatcagca
gggacccccagcctgagctcaggcgtgtcccccaagcgccgggctttgccatccgttgct
ggcctcttcactcagtcttcagggtcacccctcaacctgaattctatggtcaacaacatt
aaccagcctttggaaatcacagccatctcgtcccctgagagctccctgaagagttctcct
gtaccttaccaggacaacgaccagccgcccgtgctcaagaaagagaagcccctgagccag
accaatggggctcactactctcctctgacctctgatgaggagccgggctctgaggaagag
caaggcagcaccagaattgagagaaaaattgcaactatctccttagaaagcaaatctcct
ccaaaaaccttggaaaatggtggcagcctggtaggaaggaagccgataccctccagcgag
cccatcaacagcagcaagtggaagtccaccttctcacccatcgccgacctcagcctggcc
aaggctgctgacagcccactacaggccagctccgctctgagccagaactccctgttcact
tttcggccaaccctagaggagcttggctcggttgatgccaagctggctgcccaccccagg
aagagctttccaggttcactgtcgggggccggcgggctgagccccatcagcaaccctccc
aatggcttcaccttcagtgggagcctggctgccgatctcagtttacacagcttcagtgat
ggtgcttctctctcccacaaggcccctgaagtggccagcctgggtgcccccctgagcttt
tctgccccaaggggtaaggagggcagtgcagaaccctgcccctttgtgaacaagaggcag
ctggatggactgggtggcccaaagggcgagggggtcaagggcagggaggcagaggtcagc
ctgcctgtgtgcacgccctcagacaaggcctcatcgcatggcaaggtgggcaagagccgg
gaccgtgagcctgacttcaaaaacggccacaatctcttcatttctgccgctgctgtgcct
cctgggggcctcctcagcagtccaggcctcaccacagcagtgtcctcagcaggtggcacg
gccccctcctcccagacacaccggcccttcctgggcacttttacacctggcccacagttc
gccttgggctccatgtccctgcaggccaacctaggctcttctgtgctacagtccttgttc
agctccgtgccagctgctgctggcctagtacatgtctcatccgccgcaaccagactgacc
aactcgcacgccatgggcagcttttcctccggtgtggcaggtggcgcagttggaggtaac
tag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (2)   
   Pfam (2)   
All databases (28)   

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