KEGG   Methylobacterium nodulans: Mnod_7191
Entry
Mnod_7191         CDS       T00839                                 
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
mno  Methylobacterium nodulans
Pathway
mno00010  Glycolysis / Gluconeogenesis
mno00020  Citrate cycle (TCA cycle)
mno00620  Pyruvate metabolism
mno00785  Lipoic acid metabolism
mno01100  Metabolic pathways
mno01110  Biosynthesis of secondary metabolites
mno01120  Microbial metabolism in diverse environments
mno01200  Carbon metabolism
mno01210  2-Oxocarboxylic acid metabolism
Module
mno_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:mno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    Mnod_7191
   00020 Citrate cycle (TCA cycle)
    Mnod_7191
   00620 Pyruvate metabolism
    Mnod_7191
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    Mnod_7191
Enzymes [BR:mno01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     Mnod_7191
SSDB
Motif
Pfam: PDH_E1_M Transketolase_N Transketolase_C
Other DBs
NCBI-ProteinID: ACL61931
UniProt: B8IKE6
Position
7276567..7279236
AA seq 889 aa
MERSRDLDTRDPDPIETREWLDSLDGVLEVEGPDRAHFLIEQVIEEARKKGAPVPYSANT
AYLNTIPVEAQPRHPGDRAIEHRIRSAIRWNAIALILRANKESSELGGHIASFQSAATLY
DTGFMHFWRAASETHGGDLIYIQGHSSPGIYARAYLEGRLTEEQLLNFRQEVGGQGLSSY
PHPWLMPDFWQFPTVSMGLGPLMAIYQARYLRYLHHRGLADTDGRKVWAFMGDGEMDEPE
SLGAISLASREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEANFRGAGWNVIKVLWGSG
WDQLLARDTSGMLARLMAECVDGEYQDFKSKNGAYIREHFFGRYPETKALVADWSDEDIW
RLTRGGHDPSKVYAAYDAAVKHKGQPTVILAKTVKGYGMGEAGEGQNITHQQKKMGEAVL
KQFRDRFQIDLSDEQIGGIPFIRFPEGSPEHRYLMARRQALGGPLPARRQKSQSLAVPPL
SAFEAQLKETAGREISTTMAFVRVLNTLLRDKEIGKRIVPIVPDESRTFGMEGMFRQFGI
FSQVGQLYRPEDANQLMYYKEDKTGQMLQEGINEAGAMSSWIAAATAYSHSDAPTIPFYI
YYSMFGFQRVGDLAWAAGDLRARGFLIGGTAGRTTLNGEGLQHEDGHSHLISATIPNCIS
YDPTFSYEVAVIVQDGLRRMYAEQEDVFYYITLMNENYAHPGMPEGAEAGILKGMYLFRE
GQGSGPRVQLLGSGTILREVIAGAELLQQDFGIAADIWSCPSFTELRREAMAVERWNLLH
PTETPKKSYVETCLSGRSGPVIAATDYMRLFADQIRPFVPGRYRVLGTDGFGRSDYRVRL
RDFFEVDRRWVAVAALKSLAEDGKVPAAKVAEAIAKYGIDPAKPAPWTV
NT seq 2670 nt   +upstreamnt  +downstreamnt
gtggaacgcagccgcgatctcgacacgcgcgatcccgatccgatcgaaacccgcgaatgg
ctcgactccctcgacggcgtgctggaggtggagggtcccgaccgggcgcatttcctcatc
gagcaggtcattgaggaggcccgcaagaagggcgcgccggtcccctattccgccaacacc
gcctatctcaacaccatccccgtcgaggcccagccccgccacccgggcgaccgggcgatc
gagcaccgcatccgctccgccatccgctggaacgccatcgcgctcatcctgcgggccaac
aaggaatcctccgagctcggcggccacatcgccagcttccagtcggccgccaccctctac
gacaccggcttcatgcatttctggcgcgccgccagcgagacccacggcggcgacctgatc
tacatccagggccattcctcgccgggcatctatgcccgcgcctatctggaggggcggctc
accgaggagcagctgctcaacttccgccaggaggtcgggggccagggtctctcctcctat
ccgcatccctggctgatgccggacttctggcagttccccaccgtctcgatggggctcggg
cccctgatggcgatctatcaggcccgctacctgcgctacctgcaccaccggggcctcgcc
gacaccgacggccgcaaggtctgggccttcatgggcgacggcgagatggacgagcccgag
tccctcggcgccatctccctcgcctcgcgggaaaaactcgacaacctgatcttcgtggtg
aactgcaacctgcagcgcctcgacgggccggtgcgcggcaacggcaagatcatccaggag
ctcgaggccaatttccgcggcgcgggctggaacgtcatcaaggtgctgtggggctcgggc
tgggaccagcttctggcccgcgacacctccggcatgctggcccgcctgatggcggagtgc
gtcgacggcgagtaccaggacttcaagtccaagaacggcgcctatatccgcgagcacttc
ttcggccgctaccctgagaccaaggcgctggtcgccgactggagcgacgaggacatctgg
cggctgacccgcggcggccacgatccgagcaaggtctatgcggcctacgacgcggccgtg
aagcacaagggccagcccaccgtcatccttgccaagaccgtgaagggctacggcatgggc
gaggcgggcgagggccagaacatcacccaccagcagaagaagatgggcgaggcggtcctc
aagcagttccgcgaccgcttccagatcgacctctcggacgagcagatcggcggcatcccg
ttcatccgcttccccgaaggcagccccgagcaccgctacctgatggcccgccgccaggcg
ctcggcggcccgctgccggcccggcggcagaaatcgcagagcctcgctgtcccgccgctc
tcggccttcgaggcgcagctcaaggagacggcgggccgcgagatctccaccaccatggcc
ttcgtgcgggtgctcaacacgctcctgcgcgacaaggagatcggcaagcgcatcgtgccg
atcgtgcccgacgagagtcgcaccttcggcatggagggcatgttccgccagttcggcatc
ttcagccaggtcggccagctctaccggcccgaggacgccaaccagctgatgtactacaag
gaggacaagaccggtcagatgctccaggagggcatcaacgaggccggcgccatgtcgtcc
tggatcgcggcggcgaccgcctattcgcattccgacgcgccgacgatcccgttctacatc
tactactcgatgttcgggttccagcgggtcggcgacctcgcctgggcggcgggcgacctc
agggcgcggggcttcctgatcggcggcacggccgggcgcaccacgctcaacggcgagggt
ctgcagcacgaggacggccacagccacctgatctcggccaccatccccaactgcatctcc
tacgacccgaccttctcgtacgaggtcgcggtgatcgtgcaggacggcctgcggcggatg
tatgccgagcaggaggacgtcttctactacatcaccctgatgaacgagaactacgcccat
ccgggcatgccggagggggcggaagcgggcatcctcaaagggatgtacctgttccgcgaa
gggcagggttcggggccgcgggtgcagctcctcggctcgggcaccatcctgcgcgaggtg
atcgccggggcggagctgctgcagcaggatttcgggatcgcggcggatatctggtcctgc
ccgagcttcaccgagctgaggcgcgaggcgatggccgtggagcgctggaacctgctgcac
ccgaccgagacgccgaagaagtcctatgtcgagacctgcctgtcgggccgctccggcccg
gtgatcgcggccaccgactacatgcggctcttcgccgaccagatccgtcccttcgtgccc
ggccgctaccgggtgctgggcacggacgggttcggccgctccgactaccgggtgcgcctg
cgcgacttcttcgaggtcgaccggcgctgggtggcggtggcggcgctgaagagcctcgcc
gaggacggcaaggtgccggcggccaaggtggcggaggcgatcgccaagtacggcatcgat
ccggccaagcccgccccctggacggtgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (36)   

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