KEGG   Mus pahari (shrew mouse): 110320362
Entry
110320362         CDS       T05929                                 
Symbol
Plce1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
mpah  Mus pahari (shrew mouse)
Pathway
mpah00562  Inositol phosphate metabolism
mpah01100  Metabolic pathways
mpah04014  Ras signaling pathway
mpah04015  Rap1 signaling pathway
mpah04020  Calcium signaling pathway
mpah04024  cAMP signaling pathway
mpah04070  Phosphatidylinositol signaling system
mpah04919  Thyroid hormone signaling pathway
mpah04933  AGE-RAGE signaling pathway in diabetic complications
mpah05205  Proteoglycans in cancer
Module
mpah_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mpah00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    110320362 (Plce1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    110320362 (Plce1)
   04015 Rap1 signaling pathway
    110320362 (Plce1)
   04020 Calcium signaling pathway
    110320362 (Plce1)
   04070 Phosphatidylinositol signaling system
    110320362 (Plce1)
   04024 cAMP signaling pathway
    110320362 (Plce1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    110320362 (Plce1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    110320362 (Plce1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    110320362 (Plce1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mpah04131]
    110320362 (Plce1)
Enzymes [BR:mpah01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     110320362 (Plce1)
Membrane trafficking [BR:mpah04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    110320362 (Plce1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    110320362 (Plce1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like UNC80_C GDPD
Other DBs
NCBI-GeneID: 110320362
NCBI-ProteinID: XP_021051991
Ensembl: MGP_PahariEiJ_G0014420
Position
1:149865113..150165421
AA seq 2297 aa
MTSEEMAASVLIPVTQRKVASAQAVAEERSEKVSDARIPQARAGRQGALIPPTISQWNKR
KEESSRSDLSKVFSIARGELISDENHNEEGWEETAPDSTVNHAINCSSLVQSHQHQLPQN
QLCEARDSVPEEDPSMQPGIPYPLERKVLPGIQLEMEDSPMDVSPSGSQPGIMESSGPHS
DGHTAVFHFHYEADRTMPDAFHALSENLILDDCANCVTLPGGQQNKNCMAYTCKLVELTR
TCGSKNGQLKCEHCTSLRDEYLCFENSCPKADEVCSGGGFCEDGFAQGPAAKTFLSPLED
FSGNCEDVDDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGRIGPAAWNY
VDQKKAGLLWPCGNVMGPLSAMDIRQSGSQRLTEAQWCLIYSAVRRGEETEETVGSLRHC
ATQLPNSETAHGSLGDGPCLKQCVRDTECEYRATLQRTSIAQYITGSLLEATTSLGARSG
LLSPFGGSTGRIMLKERQPGTSMANSNPVPSSSAGISKELIDLQPLIQFPEEVASILTEQ
EQNIYRRVLPMDYLCFLTRDLSSPECQRSLPRLKASISESILTSQSGERNALEDLVMRFN
EVSSWVTWLVLTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQF
MDQSDIETMRSLKDAMAQHESSVEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASG
LLKLCPRYSSQEEALEFVADYSGQDNFLQRVGQNGLKNSEKELTVNSIFQIIRSCSRSLE
MEEEDSASEGSGSRKNSLKDKARWQFIIGDLLDSENDIFEKSKECDPHGSEESQKAFDHG
TELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWMKPPTASPA
GARPKLGVLSNTAEPGKFPSPGNAGVSGLAEGILDLFSVKAVYMGHPGIDIHTVCVQNKL
SSMLLSETGVTLLYGLQTTDNRLLHFVAPKHTAEMLFSGLLELTTAVRKIRKFPDQRQQW
LRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGMSAKNAEKPNMQRNNTLGIS
TTKKKKKMLMRGESGEVTDDEMATRKAKIYRECRSRSGSDPQDVNEQEELEANVITNPPN
TLHSRRAYSLTTAGSPNLATGMSSPISAWSSSSWHGRIRGGMKGFQSFMVSDSNMSFVEF
VELFKSFSIRSRKDLKDIFDIYSVPCNRSASESAPLYTNLTIEENTSDLQPDLDLLTRNV
SDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFGVGILQLNDFLVNCQG
EHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNFASKNDESRENKKELQLPL
SYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCWDGDDGMPIIYHGHTLTT
KIPFKEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEIFKSVFGEKLVAKFLFETD
FSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAFTGGNANPPPAS
NEEEEDEEDEYDYDYESLSDADVLTASPVPNSQEDNILEDRPENKLCADKLQFEYNEEGP
KRIKKADNSSGNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLN
SSGSSRGKERKSRKSIFGNNPGRMSPGETAPFNRTSGKGSCEGMRQTWEESSPLSPSTSL
SAIIRTPKCYHISSLNENAAKRLCRRCSQKLIQHTACQLLRTYPAATRIDSSNPNPIIFW
LHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKSCPMYQKFSPLERDLDT
LDPAIYSLTIISGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFL
FRVHFEDLVFLRFAVVENNSSAITAQRIIPLRALKRGYRHLQLRNLHNEILEISSLFINS
RRMEENPSGSTMPASLMFNTEERKCSQTHKVTVHGVPGPEPFAVFTINEGTKAKQLLQQV
LEVGQGTKHTATDYFLMEEKHFISKEKNECRKQPFQRAVGPEEDIVQILNSWFPEEGYVG
RIVLKPQQETLEEKSIVYDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVI
QQTLCKAKYSYSILNNPNPCDYVLLEEVMKDAPNKKSSTPKSSQRILLDQECVFQAQSKW
KGAGKFILKLKEQVQASREDKRRGISFANELKKLTKSTKQSRGLTSPPQFVASESVQSKE
EKPVGALAAGDTVGYQQ
NT seq 6894 nt   +upstreamnt  +downstreamnt
atgacgtccgaagaaatggccgcttccgtcctcatccctgtgactcaaaggaaagtggct
tctgcccaggcagtggcagaagagaggagtgaaaaggtctcagatgcccggattcctcag
gcacgtgctggcaggcagggtgcgctcatccctcctaccatctcacagtggaacaaacgt
aaggaagagtcttctagaagtgatttgtccaaggtcttctcaatagcgaggggggaacta
atcagcgatgagaatcacaacgaagagggctgggaggaaaccgcaccggactccacggta
aaccatgcgattaactgcagcagcttagtgcaaagccaccagcaccagcttccccagaac
cagctttgtgaagcccgtgactctgtcccagaagaagacccgagtatgcagcctggaatt
ccttacccactggaaaggaaggtgcttcctggaattcaactggagatggaggactctccc
atggacgtgagcccttcgggaagtcagcctgggatcatggagtccagcggacctcactct
gacggccacacggcggtatttcacttccattatgaagctgacaggacaatgccggatgct
tttcatgccctgtcagaaaacttgattttggatgactgtgcaaattgtgttactcttcct
ggggggcagcaaaataaaaattgcatggcgtatacttgcaaactggtggagttaacaaga
acctgtggaagtaagaatgggcagctcaagtgtgagcactgtacttcgctgcgcgatgaa
tacctgtgcttcgaaaattcctgcccaaaggccgatgaggtctgctcaggtggtggcttt
tgcgaggacggctttgctcagggtcctgctgccaagacttttctgagccctctggaggat
ttctcaggcaattgtgaagacgtagacgatttttttaaaagcaaaaaggagcggtccact
ttgttagtccgaaggttttgtaaaaatgacagggaagttaagaagtctgtgtatactggg
acaagagccatcatgagaactctgccttccggccgtattgggccggctgcttggaattat
gttgatcagaagaaagctggtctcctatggccttgtgggaatgtaatgggacctctgtca
gcaatggacataaggcaaagtgggagccaacgtctgactgaagcccagtggtgcctgatc
tacagtgccgtgagaagaggggaagaaacagaagaaacggtcggatctcttcgccattgc
gccacacagctcccaaactctgagacagcccatggaagtcttggagacggtccctgctta
aagcagtgtgtacgagacactgaatgtgagtaccgtgctaccctgcaaaggacgtccata
gctcagtacatcaccggttctctcctcgaggcaaccacatctttaggagcaagaagcggc
cttctcagtcccttcggaggatccactggacggataatgctgaaagaacgccaaccaggc
acctctatggccaattctaatcctgttccttcaagttcagctggaatcagcaaggagctg
attgatctccagcccctcattcagttcccggaggaagtggccagcatcttaacagagcag
gagcagaacatttaccgcagggtgctgcccatggactacctctgtttcttaacccgggac
ttgagttcacctgaatgccagagatcactgccccgtctcaaagcatccatctcagaatcc
atcctcacgtctcaaagtggagaacgcaatgcccttgaagaccttgtgatgagatttaac
gaggtgagctcctgggtaacgtggctggtcctcacggcaggctccatggaggagaagcgg
gaagtcttctcttatttggtgcatgtggccaaatgctgctggaacatgggcaactacaac
gctgtcatggagttcctggctggcctcaggtcaaggaaagttctaaagatgtggcagttc
atggaccagtctgacatcgagaccatgcggagcctgaaggatgccatggctcagcacgag
tcttccgtcgagtacaagaaggtagtgacccgagccttgcacatccccggctgcaaagtc
gtccctttctgtggggtgttcctgaaggagctctgtgaagtgctggatggtgcctctggt
ctcctgaagctctgcccacggtacagctcccaagaagaagctctggagtttgtagccgat
tacagtggacaagacaacttcttacaacgagtgggacagaatggcttaaagaattcagag
aaggagctcacggtcaacagcatctttcagatcatccggagctgcagccgaagtttggag
atggaggaggaggacagtgccagcgaagggagcggctctagaaaaaactccttgaaggac
aaagcccgatggcagtttataattggagatttgctggattcagaaaatgacatctttgag
aagtccaaagagtgtgaccctcatggatcagaggagtcacagaaagcctttgaccatggg
acggagctcatcccatggtacgtgctgtccatccaagcggatgtgcaccagttcctattg
cagggggccacagtcatccactatgaccaggacacacatctctccgcccgctgctttctc
cagttgcagcctgacaatagcacgttgacctggatgaaacctcccactgcctccccagcc
ggtgccagacccaagctcggcgtgcttagtaacacggccgagcccggcaagttcccatca
ccgggcaacgccggggtgagcggcctggcagagggaatcctggatctgttctcagtgaag
gctgtgtatatgggacaccctggcattgatatacacactgtgtgtgtccagaacaaactt
agtagcatgcttctatcggagacgggggtcaccctgctctatgggcttcagaccactgac
aatagattactgcactttgtggcgccaaagcacacagccgagatgcttttcagtggattg
ctggaacttactacagctgtgagaaagataaggaagttccctgaccaacgacagcagtgg
cttcggaaacagtatgtcagcctctatcaggaggatggtcggtatgaaggcccaaccttg
gcacatgctgtggagttgtttggtggtaggcggtggagcactagaaaccccagtcctgga
atgtcggcaaagaatgctgagaagcccaacatgcagagaaacaacaccctgggcataagc
accaccaagaaaaagaagaaaatgctcatgaggggagagagtggagaggtgacggacgat
gagatggctacccgcaaggccaaaatatacagagagtgtcgcagccggagcggctctgat
cctcaagacgttaacgaacaagaagagttggaggccaatgtcatcactaaccctcccaac
accctccattccagaagagcctactctttgaccacggctgggtcccccaacttggctacc
gggatgtcatctcccatcagtgcctggagcagcagcagctggcatgggcgaatccgagga
gggatgaaaggcttccagagcttcatggtttcagacagtaacatgagtttcgttgaattc
gttgagctgttcaaatcattcagcatcaggagccgcaaggacttgaaggacatctttgac
atctactccgtaccctgcaatcggtctgcctcggagtcagctccactctacaccaacctg
acaatcgaagaaaataccagtgaccttcagcctgacctagatttgctgactagaaacgtc
tccgacttggggctgttcattaaaagtaaacagcagctttctgacaaccagaggcagata
tctgatgctatcgctgctgcaagcattgtaaccaatggcactgggattgaaagcacgtcc
ctgggcatatttggggtcggcatactccagctcaatgatttcctggtgaattgccaagga
gaacactgcacgtatgatgaaatcctgagcatcatccagaaatttgagccgagcgtcagc
atgtgtcatcaaggcctattgtcatttgaagggtttgcaaggtttctgatggataaagac
aatttcgcctcaaaaaatgacgagtcacgggagaacaagaaagagctgcagctacccctc
tcctactattacattgagtcttcacacaacacctacctcaccggccatcagctcaagggg
gagtcctctgtggagctctatagccaggtcctcctgcaaggatgtagaagcatagagctg
gactgctgggatggggatgatgggatgcccatcatctatcatgggcatacactgacaacc
aagatccccttcaaggaagtggtggaagccatcgatcgcagtgccttcatcacctcagac
ctgccaatcatcatatccattgagaaccattgttcattgcctcaacaacgaaaaatggca
gaaattttcaagagtgtgtttggagaaaagctggtggctaagttcttattcgagaccgat
ttctcagatgacccaatgcttccctcacctgatcagcttagaaggaaagtgctccttaaa
aacaagaagctaaaggcccatcagacacctgtcgacatcctaaaacaaaaggctcatcag
ttagcatccatgcaagcacaggctttcactggtgggaatgccaacccgccacctgccagt
aatgaggaagaggaagatgaggaggacgaatatgattatgattacgagtccctttccgat
gcagatgtccttactgcttcccctgttcctaacagtcaggaagacaacattctggaagac
agacctgagaacaaattatgcgctgacaagcttcagtttgagtacaatgaagaaggccca
aagaggataaagaaagcagacaactcctctggcaataagggaaaggtgtatgacatggaa
ctgggagaggagttttaccttccacagaacaaaaaagaaagcaggcagattgcaccagag
ctctctgacctcgtcatttattgccaggcagtaaaatttccaggcctgtcaactctaaat
tcatctggctctagcagagggaaagaaaggaaaagcaggaagtccatttttggcaacaat
cctggcagaatgagcccaggggagacagcaccatttaacagaacatctggaaaaggttcc
tgtgaagggatgcgacaaacctgggaggaatcttctccactcagcccgagtacatccctc
agcgctatcattagaactcctaaatgctatcatatctcctcactgaatgagaacgccgcc
aaacgtctgtgccgcaggtgttctcagaaactgatccagcacaccgcttgccagctgctg
agaacctaccccgcagcgaccagaattgactcctccaatcccaaccccatcatattctgg
ctccatgggatacagcttgtagctctaaactaccagacggatgaccttcctttacattta
aacgctgccatgtttgaggccaatggtgggtgtggttacgttctgaagccccctgtcctg
tgggataaaagctgtcccatgtaccagaagttttccccactggaaagagacctagacacc
ctggatcctgctatctactctttaactatcatctctggccagaatgtgtgccctagtaac
agcaccggaagtccatgcattgaagttgacgtcttgggcatgcccctggacagctgccat
ttccgaacaaaacccatccatcgaaacactctgaatcccatgtggaatgagcagtttctc
ttccgggttcactttgaagatcttgtatttcttcgttttgcggttgtggaaaacaacagt
tcggcgataacagctcagagaatcattccactcagagctttaaaacgaggatatcgacat
cttcagctgcggaacctccacaatgaaatcttggaaatctctagcttattcataaacagc
agaaggatggaagaaaacccctctggcagtaccatgccagcctcattgatgtttaatacg
gaagagaggaaatgttctcagactcacaaagtcacagtgcatggtgtcccaggtccagag
ccctttgctgttttcactataaacgaaggcaccaaggcaaagcagcttctccaacaggtt
ttggaggttggccaaggcaccaaacatactgccacagactattttctgatggaagagaag
cattttatatctaaggaaaagaatgaatgcaggaaacaaccattccagagagctgtgggt
ccagaagaagatattgtgcagattttaaacagctggttcccagaagaaggctacgtaggc
aggattgtcttaaagccccaacaggaaaccttagaagagaagagcattgtctacgatgac
aaagaggtgatcttgagctcggaggaggagagtttctttgtccaagttcatgatgtctct
cctgagcaacctcgaactgtcatcaaagccccgcgtgtcagcactgcacaggatgtgatt
cagcagaccttatgcaaagccaagtattcctacagcatcctgaacaaccccaacccatgt
gactatgtgcttttggaagaggtgatgaaagacgcacctaataagaagtcttctacccca
aagtcctcacagaggatcctcttggaccaagaatgtgtgtttcaagcccaaagcaagtgg
aagggtgcagggaaattcatccttaagctaaaggagcaggtgcaggcatcccgagaagac
aaaaggaggggtatctcctttgcaaatgaactcaagaaactcactaagtccactaagcag
tcccgagggctcacgtcacctcctcagtttgtggcctcggaaagtgttcaaagcaaggag
gagaaacctgtgggtgccttggccgctggtgacacagtgggttaccagcagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (8)   
   Pfam (8)   
All databases (47)   

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