KEGG   Mus pahari (shrew mouse): 110325439
Entry
110325439         CDS       T05929                                 

Gene name
Adcy4
Definition
(RefSeq) adenylate cyclase type 4
  KO
K08044  adenylate cyclase 4 [EC:4.6.1.1]
Organism
mpah  Mus pahari (shrew mouse)
Pathway
mpah00230  Purine metabolism
mpah01100  Metabolic pathways
mpah01522  Endocrine resistance
mpah04015  Rap1 signaling pathway
mpah04020  Calcium signaling pathway
mpah04022  cGMP-PKG signaling pathway
mpah04024  cAMP signaling pathway
mpah04062  Chemokine signaling pathway
mpah04072  Phospholipase D signaling pathway
mpah04114  Oocyte meiosis
mpah04211  Longevity regulating pathway
mpah04213  Longevity regulating pathway - multiple species
mpah04261  Adrenergic signaling in cardiomyocytes
mpah04270  Vascular smooth muscle contraction
mpah04371  Apelin signaling pathway
mpah04540  Gap junction
mpah04611  Platelet activation
mpah04713  Circadian entrainment
mpah04714  Thermogenesis
mpah04723  Retrograde endocannabinoid signaling
mpah04724  Glutamatergic synapse
mpah04725  Cholinergic synapse
mpah04727  GABAergic synapse
mpah04742  Taste transduction
mpah04750  Inflammatory mediator regulation of TRP channels
mpah04911  Insulin secretion
mpah04912  GnRH signaling pathway
mpah04913  Ovarian steroidogenesis
mpah04914  Progesterone-mediated oocyte maturation
mpah04915  Estrogen signaling pathway
mpah04916  Melanogenesis
mpah04918  Thyroid hormone synthesis
mpah04921  Oxytocin signaling pathway
mpah04923  Regulation of lipolysis in adipocytes
mpah04925  Aldosterone synthesis and secretion
mpah04926  Relaxin signaling pathway
mpah04927  Cortisol synthesis and secretion
mpah04928  Parathyroid hormone synthesis, secretion and action
mpah04934  Cushing syndrome
mpah04935  Growth hormone synthesis, secretion and action
mpah04970  Salivary secretion
mpah04971  Gastric acid secretion
mpah04972  Pancreatic secretion
mpah04976  Bile secretion
mpah05032  Morphine addiction
mpah05163  Human cytomegalovirus infection
mpah05166  Human T-cell leukemia virus 1 infection
mpah05200  Pathways in cancer
mpah05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:mpah00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    110325439 (Adcy4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    110325439 (Adcy4)
   04371 Apelin signaling pathway
    110325439 (Adcy4)
   04020 Calcium signaling pathway
    110325439 (Adcy4)
   04072 Phospholipase D signaling pathway
    110325439 (Adcy4)
   04024 cAMP signaling pathway
    110325439 (Adcy4)
   04022 cGMP-PKG signaling pathway
    110325439 (Adcy4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    110325439 (Adcy4)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    110325439 (Adcy4)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110325439 (Adcy4)
   04062 Chemokine signaling pathway
    110325439 (Adcy4)
  09152 Endocrine system
   04911 Insulin secretion
    110325439 (Adcy4)
   04923 Regulation of lipolysis in adipocytes
    110325439 (Adcy4)
   04912 GnRH signaling pathway
    110325439 (Adcy4)
   04913 Ovarian steroidogenesis
    110325439 (Adcy4)
   04915 Estrogen signaling pathway
    110325439 (Adcy4)
   04914 Progesterone-mediated oocyte maturation
    110325439 (Adcy4)
   04921 Oxytocin signaling pathway
    110325439 (Adcy4)
   04926 Relaxin signaling pathway
    110325439 (Adcy4)
   04935 Growth hormone synthesis, secretion and action
    110325439 (Adcy4)
   04918 Thyroid hormone synthesis
    110325439 (Adcy4)
   04928 Parathyroid hormone synthesis, secretion and action
    110325439 (Adcy4)
   04916 Melanogenesis
    110325439 (Adcy4)
   04925 Aldosterone synthesis and secretion
    110325439 (Adcy4)
   04927 Cortisol synthesis and secretion
    110325439 (Adcy4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110325439 (Adcy4)
   04270 Vascular smooth muscle contraction
    110325439 (Adcy4)
  09154 Digestive system
   04970 Salivary secretion
    110325439 (Adcy4)
   04971 Gastric acid secretion
    110325439 (Adcy4)
   04972 Pancreatic secretion
    110325439 (Adcy4)
   04976 Bile secretion
    110325439 (Adcy4)
  09156 Nervous system
   04724 Glutamatergic synapse
    110325439 (Adcy4)
   04727 GABAergic synapse
    110325439 (Adcy4)
   04725 Cholinergic synapse
    110325439 (Adcy4)
   04723 Retrograde endocannabinoid signaling
    110325439 (Adcy4)
  09157 Sensory system
   04742 Taste transduction
    110325439 (Adcy4)
   04750 Inflammatory mediator regulation of TRP channels
    110325439 (Adcy4)
  09149 Aging
   04211 Longevity regulating pathway
    110325439 (Adcy4)
   04213 Longevity regulating pathway - multiple species
    110325439 (Adcy4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    110325439 (Adcy4)
   04714 Thermogenesis
    110325439 (Adcy4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110325439 (Adcy4)
  09165 Substance dependence
   05032 Morphine addiction
    110325439 (Adcy4)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    110325439 (Adcy4)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    110325439 (Adcy4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    110325439 (Adcy4)
   05163 Human cytomegalovirus infection
    110325439 (Adcy4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    110325439 (Adcy4)
Enzymes [BR:mpah01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     110325439 (Adcy4)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N CD52
Other DBs
NCBI-GeneID: 110325439
NCBI-ProteinID: XP_021059104
Ensembl: MGP_PahariEiJ_G0030336
Position
8
AA seq 1072 aa
MARLFSPRPPPSEDLFYETYYSLSQQYPLLILLLVIVLCALVALPAVAWASGRELTSDPS
FLTTVLCAFGGFSLLLGLASREQQLQRWTRPLSGLIWVALLALGYGFLFTGGVVSAWDQV
SFFLFIIFTVYAMLPLGMRDAAAAGVISSLSHLLVLGLYLGWQLESQRALLPQLAANAVL
FLCGNVVGAYHKALMEQALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQHSGPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRQLRVATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLDLLAG
AYAVERADAEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAKGLLSSLEGHPMRPSLLMTR
YLESWGAAKPFAHLSHLDSPVSTSTPLPEKAFSPQWSLDRSRTPRGLDDELDTGDAKFFQ
VIEQLNSQKQWKQSKDFNLLTLYFREKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQM
LVTARPPSLIITYSITFLLFFLLLFVCFSEHLTKCVQKGPKMLHWLPALSVLVATRPGFR
VALGTATILLVFTMAIASLLFLPVSSDCLFLASNVSSVTFNASWELPGPLPLISIPYSMH
CCVLGFLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLIARLYQSPLDSRPG
VLKEPKLMGAIYFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLE
NVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLN
EIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDTQQDAERSCSHLGTMVEFA
VALGSKLGVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVL
GKIQVTEETARALQSLGYTCYSRGSIKVKGKGELCTYFLNTDLTRTGSPSAS
NT seq 3219 nt   +upstreamnt  +downstreamnt
atggctcgcctcttcagtccccggcctcctcccagcgaagatctcttctatgagacttac
tacagcctgagccaacagtacccactgctgatactgcttttggtcattgtgctctgcgcg
ctcgtggcactgcccgccgtcgcctgggccagcggcagggagctgacttcagacccaagc
ttcctgacaactgtgctgtgtgcttttggtggcttctctctgttattgggactcgcttcc
cgggagcagcaactgcagcgatggacacgacctctttccggtctcatatgggttgcattg
ctggctctgggttatggatttctgttcactgggggtgtggtgagcgcctgggaccaggtg
tcttttttcctcttcatcatcttcaccgtgtacgccatgctgcccttgggcatgcgggat
gctgctgctgcgggggtcatctcatccctctcgcacctgctggtccttggactgtatctt
gggtggcagcttgagtcacagagagctctgctaccacagttggcagcaaacgcggtgttg
ttcctgtgtgggaacgtggtgggggcgtaccacaaggccctgatggagcaagcactgcgg
gccacgttccgggaggctcttagctctctgcattcacgccggaggttggacactgagaaa
aagcaccaggagcacctcctcttgtccatccttcctgcctacctggcccgagagatgaaa
gcagagatcatggcccggctgcaggctggacagcactcagggccagagaacacaaacaac
tttcacagcctgtatgtcaagaggcaccaaggagtgagcgtgctgtatgccgacatcgtg
ggcttcacgcggctggccagcgagtgttccccgaaggagctggtcctcatgctgaacgag
ctctttggcaagttcgaccaaattgccaaggagcacgaatgcatgcggatcaagatcctg
ggagactgttactactgtgtctccgggctgcccctctcgctgcctgaccacgctatcaat
tgtgtgcgcatgggactggacatgtgccgggccatcaggcaacttcgggtagccaccggt
gtggatatcaacatgcgcgtgggcgtgcactcgggcagcgttctttgtggagtcatcggg
ctacagaagtggcagtatgatgtctggtcccacgatgtcacattggccaaccatatggaa
gctggcggtgtaccaggacgagtgcacatcacaggggccacgctggacctgctagcagga
gcttatgctgtggagagggcagacgcagaacaccgagacccgtaccttcgggagctaggc
gaacctacatacctggtcattgatcctcgggctgaggaggaagacgagaagggcaccgca
aaaggattgctgtcttctctggaggggcacccgatgcgtccgtcacttctgatgactcgc
tatctggagtcttggggtgcagccaagcctttcgcccacctaagccaccttgacagtccc
gtgtccacctccactccactcccggagaaagccttcagcccccagtggagcctggaccgg
agtcgcactccccggggactggacgatgagctggacactggcgatgccaagttcttccag
gtcatcgaacaactcaactctcagaaacagtggaagcagtcaaaggacttcaacctcctg
acgttgtacttcagagagaaggagatggagaaacagtatcggctctctgcactccccgcc
ttcaaatactacgcagcctgcaccttcctggtttttctgtccaacttcactatccaaatg
ctggtgacagccaggcccccatctctgatcatcacctacagcatcaccttccttctcttc
tttctcctcctgttcgtctgcttctcagagcacctgacgaagtgtgtccagaaaggtccc
aagatgttgcactggttgcctgcactgtctgtcctggtggccacacggccaggatttcga
gtagccctgggcacggccaccatcctcttggtattcactatggccatcgccagcctgctc
ttcttaccagtgtcatcagactgccttttcctggcttccaatgtgtcctctgtgactttc
aatgcttcctgggagctgccaggacccctgcctctcatcagcatcccatactccatgcat
tgctgcgtgttgggtttcctctcctgctccctttttctgcacatgagcttcgaactgaag
ctgctcctgcttctgctgtggctggtggcatcttgttccctatttctgcattcccacgcc
tggctgtccgactgcctcattgcccgcctttatcaaagccctttggactccaggccaggg
gtactgaaggaacccaagctgatgggagctatctacttcttcatcttcttcttcacgctt
ctggtcctggctcggcagaatgagtattactgccgcctggacttcctgtggaaaaagaaa
ctgaggcaggagcgagaggagactgagacgatggagaacctgacccggctcctcctggag
aatgtactccctgcacacgtggccccccagttcatcggccagaaccggcgcaatgaggac
ctctaccaccagtcgtacgaatgtgtttgtgtcctcttcgcatcggtcccagactttaag
gaattctactctgaatccaacatcaaccacgaggggctggagtgcctgcggctgctcaat
gagatcattgctgactttgatgagctgctctccaagccaaagttcagtggagtagagaag
atcaaaactattggcagtacctacatggctgccacaggcttaaatgctacctctggacag
gatacgcaacaggatgctgagagaagctgcagtcacctgggcaccatggtggaatttgca
gtggccctggggtctaagctgggcgtcatcaacaagcactcgttcaacaacttccgcctg
cgtgtggggttgaaccatggaccagtagtagcaggagtgattggggcgcagaagccacag
tatgacatctgggggaacacagtgaatgtggccagccgcatggagagcacaggcgttctc
ggcaagatccaagtgacagaggagacagctcgggccctgcagtccctgggttacacgtgc
tacagcagaggcagtatcaaggtcaaaggcaaaggggaactctgtacctacttcctgaat
acagacctgacgaggaccggatctccctcggcatcctag

DBGET integrated database retrieval system