KEGG   Mycobacterium tuberculosis H37Ra: MRA_0517
Entry
MRA_0517          CDS       T00540                                 
Symbol
hemC
Name
(GenBank) porphobilinogen deaminase
  KO
K01749  hydroxymethylbilane synthase [EC:2.5.1.61]
Organism
mra  Mycobacterium tuberculosis H37Ra
Pathway
mra00860  Porphyrin metabolism
mra01100  Metabolic pathways
mra01110  Biosynthesis of secondary metabolites
mra01120  Microbial metabolism in diverse environments
mra01240  Biosynthesis of cofactors
Module
mra_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
mra_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:mra00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    MRA_0517 (hemC)
Enzymes [BR:mra01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.61  hydroxymethylbilane synthase
     MRA_0517 (hemC)
SSDB
Motif
Pfam: Porphobil_deam Porphobil_deamC FrhB_FdhB_N
Other DBs
NCBI-ProteinID: ABQ72240
UniProt: A5TZP0
Position
603167..604096
AA seq 309 aa
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
NT seq 930 nt   +upstreamnt  +downstreamnt
gtgatccggataggtacccggggcagcttgctggccaccactcaggccgccactgtcaga
gacgccctcatcgctggtggccactccgcggagttggtgaccatcagcaccgagggtgac
cgatccatggcgccgatcgccagtctcggggttggcgtcttcaccacggcgttgcgcgag
gcgatggaggcaggcctcgtcgatgcggcggtgcattcgtacaaggatttgccgactgcc
gccgatccaaggttcacggttgcggcgataccgccgcgcaatgacccccgcgacgcggtg
gtagcccgtgacgggctgacgctgggggaattgccggtcggatcgttggtgggcacatcc
tcgccgcggcgggccgcacagcttagagcattgggtctcggtttggaaatccgcccccta
cgaggcaacctagataccaggttgaacaaggtaagtagcggcgatcttgacgccatcgtg
gtggcccgggctggtctggcgcggctgggccgcctcgatgacgtgaccgagacgttagag
ccggtgcagatgttgcccgcgccggctcagggcgcgctcgcggtcgaatgccgcgccggc
gacagccggttggtggcagtgctggcggagttggatgacgccgacacgcgtgcggcggtc
accgccgagcgagccctgcttgccgacctggaggcaggttgctccgcaccggtgggagcg
atcgcagaagtggtcgagtccatcgatgaggacggccgtgtcttcgaggagctgtcgctg
cgcgggtgcgtggcggcgctggacggatccgacgtgatccgcgcgtccggcatcggcagt
tgcggtcgggcacgggagctggggctctcggtcgccgcggagctgttcgagctgggcgcc
cgggagctgatgtggggagtgcggcattag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (5)   
   KEGG MODULE (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (3)   
   Pfam (3)   
All databases (26)   

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