KEGG   Mycobacterium tuberculosis H37Ra: MRA_3505
Entry
MRA_3505          CDS       T00540                                 
Symbol
rmlB
Name
(GenBank) dTDP-glucose-4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
mra  Mycobacterium tuberculosis H37Ra
Pathway
mra00521  Streptomycin biosynthesis
mra00523  Polyketide sugar unit biosynthesis
mra00525  Acarbose and validamycin biosynthesis
mra00541  O-Antigen nucleotide sugar biosynthesis
mra01100  Metabolic pathways
mra01110  Biosynthesis of secondary metabolites
mra01250  Biosynthesis of nucleotide sugars
Module
mra_M00793  dTDP-L-rhamnose biosynthesis
Brite
KEGG Orthology (KO) [BR:mra00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    MRA_3505 (rmlB)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    MRA_3505 (rmlB)
   01055 Biosynthesis of vancomycin group antibiotics
    MRA_3505 (rmlB)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    MRA_3505 (rmlB)
   00525 Acarbose and validamycin biosynthesis
    MRA_3505 (rmlB)
Enzymes [BR:mra01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     MRA_3505 (rmlB)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase 3Beta_HSD RmlD_sub_bind NAD_binding_4 Polysacc_synt_2 NAD_binding_10 adh_short VbhA Sacchrp_dh_NADP KR NmrA
Other DBs
NCBI-ProteinID: ABQ75290
UniProt: A5U8E0
Position
3890514..3891509
AA seq 331 aa
MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD
AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST
DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP
YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS
EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG
LRTTIDWYRDNESWWRPLKDATEARYQERGQ
NT seq 996 nt   +upstreamnt  +downstreamnt
atgcggttgctagtcaccggtggcgcgggattcatcggcacgaatttcgtgcacagcgcc
gtacgtgagcatccagacgatgcggttaccgtactcgacgccctgacctacgccggccgg
cgcgagtcgctggccgacgtggaggatgccatccggctggttcagggcgatatcaccgac
gccgagctggtttcgcagctggtggccgagtccgacgcggtggtgcattttgccgccgaa
tcccatgtcgacaatgcactggacaatccggagccgtttctgcacaccaacgtcatcggg
accttcaccatcctggaagcggtgcgacgccacggtgtgcgcctgcaccacatctccacc
gacgaggtctacggcgacttggagctcgacgaccgggcgcggttcaccgaatcgacgccc
tataacccgtccagcccttactcggcgaccaaggcgggcgcagacatgttggtccgggcc
tgggttcggtcctatggcgtacgcgcgacgatctccaactgctccaacaactacgggccg
tatcagcacgtcgagaagttcattccgcgtcagatcaccaatgtgctcaccgggcggcgg
cccaagctctacggcgcgggcgccaatgtccgtgactggatccacgtcgacgaccacaac
agcgcggtgcggcgaatcctggacagaggccgcatcggccgaacctacctgatcagctcc
gagggcgagcgtgacaacctgaccgtgctgcgcacgctgctgcgactgatggaccgcgat
ccggacgacttcgaccacgtcaccgaccgcgtcggccacgacctgcgctatgccatcgac
ccgtccacgctctacgacgaattatgctgggcgccaaagcataccgatttcgaggagggc
ctgcggaccacgatcgactggtaccgcgacaacgaatcgtggtggcgtccactaaaagac
gccacggaggcccgctatcaagaacgcggtcaatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (12)   
   Pfam (12)   
All databases (32)   

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