KEGG   Methylobacterium radiotolerans: Mrad2831_3056
Entry
Mrad2831_3056     CDS       T00674                                 
Name
(GenBank) delta-1-pyrroline-5-carboxylate dehydrogenase
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
mrd  Methylobacterium radiotolerans
Pathway
mrd00250  Alanine, aspartate and glutamate metabolism
mrd00330  Arginine and proline metabolism
mrd01100  Metabolic pathways
mrd01110  Biosynthesis of secondary metabolites
Module
mrd_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:mrd00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    Mrad2831_3056
   00330 Arginine and proline metabolism
    Mrad2831_3056
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mrd03000]
    Mrad2831_3056
Enzymes [BR:mrd01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     Mrad2831_3056
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     Mrad2831_3056
Transcription factors [BR:mrd03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    Mrad2831_3056
SSDB
Motif
Pfam: Pro_dh Aldedh Pro_dh-DNA_bdg PRODH
Other DBs
NCBI-ProteinID: ACB25038
UniProt: B1M5K8
Position
complement(3225389..3229075)
AA seq 1228 aa
MSGSGVVDDAAVGASEPFGLFAPALADRSPLRQAVIAACRRPEAGCVAALLAEARLPPDA
ARRVAEHARRLVESLRRQGRRGGVEGLIHEYALSSQEGVALMCLAEALLRIPDAATRDAL
IRDKIAGGDWAAHLGHSPSPFVNAATWGLLVTGKLTATRDEAGLSAALTRLIARGGEPVI
RKGVDLAMRMMGEQFVAGRTIAEALRHAAPLEAKGFTYSYDMLGEAAVTAEDAERFRRAY
AEAIAAIGAASAGRGVLLGPGISIKLSALHPRYVRAQRDRVLAELYPRVLDLARRAMGHG
IGLNIDAEEADRLDLSLDILERLAADPELAGWDGLGFVVQAYGKRCPFVIDVLIDLARRC
RRRLMVRLVKGAYWDSEIKRAQVDGLSDFPVFTRKVHTDVSYLACARRLLAAPDAVFPQF
ATHNAQTLASIVAMAGPDFRLGQYEFQCLHGMGEPLYEAVMADADLQRPCRIYAPVGTHE
TLLAYLVRRLLENGANTSFVNRVADEAVPVADLIADPVAVVEAEPDPGAPHPRIAAPRDL
YGPGRANAAGLDLADEAALASLWDGLAASGRTAWRAVPSGADAAAADEPVRNPADRRDIV
GYDRPATAGTVAIAVARAEAGAAGWAATPATERAACLRRAADALEAQMPTLIGLVVREAG
KTCASAVAEIREAVDFLRYDAAEAERTLGNAHAPLGPVACIAPWNFPLAIFVGQVAAALA
AGNTVLAKPAEETPLIAAAAVRALHAAGIPAEALHLLPGDGRVGAALVEDPRVQGVMFTG
STAVAKGIQRALAERLNRFDEPVPFLAETGGQNALVVDSSALAEQVVADVIASAFDSAGQ
RCSALRILCLQEEIADRTLHMLKGALRELRVGDPRRLAVDVGPVITAEAADRIIGHVAHM
RARGFPVAQFPLPPEADAGTFVPPTLIEIGAVADVEQEVFGPVLHVLRYRRDALDALLAA
IDATGYGLTFGLHSRIDETIDHVLGRVRAGNRYVNRNIIGAVVGVQPFGGSGLSGTGPKA
GGPLSLGRLLRRAPAAARDGLAADDSGLRPFTAWLRSRHRHDLADRLEAVRYTGRAAIAL
AGPVGERNLYALRPRGRVAAVAATETALLLQLGAILGTGNAAVVIGPDGRDPVLDGLPEA
CAARVARAPDLGRAGAIVGVLFAGGADDLLALNRAVAARDGAILPIQARCPEALAAGDLY
DPAGLVEEVTTTINTAAAGGNASLMSVG
NT seq 3687 nt   +upstreamnt  +downstreamnt
atgtccggatccggcgttgtcgacgacgcagccgtcggggccagcgagccgttcggcctg
ttcgcgcccgccctggcggaccgctcgcccctgcggcaggcggtgatcgcggcctgccgg
cggcccgaagcgggttgcgtggcggcgctcctcgccgaggcgcgcctgccgcccgatgcc
gctcggcgcgtcgccgagcacgcgcggcgcctcgtcgagagcctgcggcggcagggccga
cgcggcggcgtcgagggtctgatccacgaatacgcgctgtccagccaggaaggcgtggcg
ctgatgtgcctcgccgaggcgctgctgcgcatccccgacgcggcgacgcgggacgcgctg
atccgcgacaagatcgcgggcggcgactgggcggcccatctcgggcacagtccgtcgccc
ttcgtcaacgcggcgacctggggcctgctcgtgaccggcaagctgacggcgacccgggac
gaggccggcctctccgccgcgctcacccggctgatcgcccgcggcggcgagccggtgatc
cgcaaaggcgtcgacctcgccatgcggatgatgggcgagcagttcgtggcggggcggacc
atcgccgaggccctgcggcacgcggcgccgctcgaggcgaagggcttcacctactcgtac
gacatgctcggcgaggccgccgtgaccgccgaggacgccgagcgcttccgccgcgcctac
gcggaggccatcgcggcgatcggcgcggcatcggccggccgcggcgtgctcctcggcccc
ggcatctcgatcaagctgtcggcgctccacccccgctacgtccgcgcgcagcgcgaccgg
gtcctggccgagctctatccccgcgtgctggacttggcccgccgcgccatgggccacggc
atcggcctcaacatcgacgccgaggaggccgaccgcctcgacctgtcgctcgacatcctt
gagcggctcgccgccgaccccgaactcgccggctgggacgggctcggcttcgtggtccag
gcctacggcaagcgctgccccttcgtcatcgacgtgctgatcgacctcgcccggcggtgc
cggcggcggctgatggtgcggctcgtgaagggcgcctactgggacagcgagatcaagcgg
gcgcaggtcgacggtctttcggacttcccggtcttcacccggaaagtccacaccgacgtc
tcgtacctcgcctgcgcgcggcggctgctcgccgcgcccgacgcggtcttcccgcaattc
gccacccacaacgcccagacactggcgagcatcgtcgcgatggccggcccggatttccgg
ctcggccagtacgagttccagtgcctgcacggcatgggcgaaccgctctacgaggccgtg
atggccgacgccgatctgcagcggccctgccgcatctacgcaccggtgggcacgcacgag
accctgctcgcctacctggtgcggcgcctcctggagaacggggccaacacgtccttcgtc
aaccgggtcgccgacgaggccgtgccggtcgcggacctgatcgccgaccccgtcgccgtc
gtcgaggccgagccggatcccggcgcgccccatccgagaatcgcggcgccccgggacctc
tacggcccgggccgcgcaaacgcggccgggctcgacctcgccgacgaggcggctctcgcc
agcctgtgggacgggttggcggcgagcggccgcaccgcgtggcgggcggtgccgtcgggc
gcggatgccgcggcggccgacgaacccgtgcgcaatcccgccgaccgccgggacatcgtg
ggatacgaccggccggcgacggccgggaccgtggcgatcgccgtggcgcgggcggaggcg
ggcgcggccggctgggcggcgacgccagccacagagcgcgccgcctgcctgcggcgggcc
gccgacgccctcgaggcgcagatgccgacgctgatcgggctcgtcgtgcgtgaggcaggc
aagacctgcgcgagcgccgtcgcggagatccgcgaggcggtcgacttcctccgctacgac
gccgccgaggccgagcggactctcgggaacgcgcacgcgccgctcggcccggtcgcctgc
atcgcgccgtggaatttcccgctggcgatcttcgtcggtcaggtcgcggccgccctggcg
gcgggcaacacggtcctggcgaaacccgccgaggagacgccgctgatcgcggcggctgcg
gtccgcgcgctgcacgcggccgggatccccgcggaggcgctgcacctcctgccgggcgac
ggcagggtcggcgccgccctggtcgaggatccgcgcgtgcagggcgtgatgttcaccgga
tcgacggccgtggccaagggcatccagcgcgctctggcggagcgactgaaccgcttcgac
gagccggtgccgttcctggccgagaccggcggccagaacgccctcgtggtcgattcctcg
gcgctcgccgagcaggtggtggccgacgtgatcgcctcggccttcgattccgcgggccag
cgctgctccgcgctccggatcctgtgcctgcaggaggagatcgccgaccggacgctgcac
atgctgaaaggcgccctccgggagttgcgggtgggcgatccgcggcgcctcgccgtcgac
gtcgggccggtcatcaccgccgaggccgccgatcggatcatcggccacgtggcgcacatg
cgcgcgcgaggcttcccggtggcgcagttccccctgccgcccgaagccgacgccgggacc
ttcgtgccgccgaccctgatcgagatcggggccgtcgccgatgtcgagcaggaggtgttc
gggccggtgctgcacgtgctgcgctatcgccgcgacgccctcgacgcgctcctcgcggcg
atcgacgcgaccggctacggactcaccttcgggctgcacagccgcatcgacgagaccatc
gatcacgtcctcggccgcgtgcgggccggcaaccgctacgtgaaccgcaacatcatcggt
gcggtcgtcggcgtgcagcccttcggcggctccgggctgtcggggacgggcccgaaggcc
ggcggcccgctttccctcggccgcctgctgcgccgcgcgcccgccgccgcccgcgacggg
ctggccgccgacgattcgggtctgcgtcccttcacggcgtggctgcgctcgcggcaccgg
cacgacctcgcggacaggctcgaagccgtccgatataccggccgcgccgcgatcgcgctg
gccggtcccgtcggtgagcgcaacctgtacgcgctgcgtccccgcgggcgcgtcgcggcc
gtcgccgccaccgagacggcgctcctgctccagctcggcgcgatcctcggcacgggcaac
gcggccgtcgtcatcgggccggacgggcgcgatccggtcctggacggtctgccggaagcg
tgcgcggcgcgggtcgcccgggcgccggatctcgggcgcgcgggcgcgatcgtcggggtc
ctgttcgcgggcggcgccgacgacctgctggccctgaacagggccgtcgcggcgcgcgac
ggcgcgatcctgccgatccaggcccgctgcccggaggcgctggcggccggcgacctctac
gatccagccggcctggtggaggaggtcaccaccacgatcaacaccgcggcggccggcggc
aatgccagcctgatgagcgtcgggtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (15)   
   KEGG COMPOUND (15)   
Chemical reaction (10)   
   KEGG ENZYME (2)   
   KEGG REACTION (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (42)   

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