KEGG   Microbulbifer thermotolerans: A3224_05210
Entry
A3224_05210       CDS       T04393                                 
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
mthd  Microbulbifer thermotolerans
Pathway
mthd00300  Lysine biosynthesis
mthd00550  Peptidoglycan biosynthesis
mthd01100  Metabolic pathways
mthd01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:mthd00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    A3224_05210
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    A3224_05210
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    A3224_05210
Enzymes [BR:mthd01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     A3224_05210
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: AMX02059
UniProt: A0A143HK13
Position
1241201..1242580
AA seq 459 aa
MISAISLQQLQTRFGGELINGSVQFEQVCTDTRQLDSNALFVALKGERFDAHDFVGELEG
QVLGLVVDREIPGSKLPQWRVADTTEALGQIGRMCREQFKGRVIAVTGSCGKTTVKEMLA
AIFSQRHNPCVTRGNLNNQFGLPMTLFELTSDHDVLILEMGASGPDEIAYLCGIAKPQVS
AVNNVMPAHVEGFGSVDAIARAKGKIYTGLETGGTAVVNADDDYANYWLERMPEGVHTLE
VGLGHQWPIHADNIALDDNGCPTFDLCIEGLAYRVRLQLLGEHNVHNALVAAGCAFAAGV
PAAEIASGLQSLGGVAGRMQELCGIKGAAIIDDTYNANPGSVAAAIELLAQRRGKRVLVL
GDMAELGADAEEMHRQMGELARERGLDALFTLGPLGAAASVAFSAGRHLPLHSYRDRQPL
IAALTHELNKNTTVLVKGSRSARMELVVQALCGNAKEDK
NT seq 1380 nt   +upstreamnt  +downstreamnt
atgatcagcgccatctccctgcagcaacttcaaacgcgtttcggcggtgagctcatcaat
ggttcggtgcagtttgaacaggtgtgcaccgacacgcgccagctggattccaacgccctc
tttgtcgccttgaagggggagcgtttcgatgcgcacgactttgtcggcgaactcgaaggg
caggtattggggctggtagtggatcgggaaattcccggcagcaagctgccacagtggcgg
gtggccgataccactgaggccctcgggcagataggccgcatgtgccgggaacagtttaaa
ggccgggtgatcgcggtgactggctcctgcgggaaaactacggtcaaggaaatgctcgcg
gcgatattttcccagcggcataacccctgtgtgacccgtggcaatttgaacaatcagttc
ggcctgcccatgaccctgttcgagctgacttcagatcatgatgttttgattctggagatg
ggcgccagtggtccggatgagatcgcttatctgtgcggcattgcgaaaccccaggtgagt
gcggtcaacaacgtcatgccggcccatgtggaaggcttcggttctgtggacgccatagct
agggccaaggggaagatctacaccggtctcgaaaccggcggcacagctgtggtcaatgcc
gatgacgactacgcgaactattggctggagcggatgccggagggggtgcacacgctggaa
gtgggattggggcatcagtggcccatccacgcggacaatattgcacttgatgataatggg
tgccccaccttcgatttgtgcatcgaaggcttggcgtaccgcgtgcggttgcaattgctt
ggcgaacacaatgtgcacaatgcgctggtggccgccggctgcgcctttgccgccggtgtc
cctgcggcggaaatcgccagtggcctgcaaagcctgggtggcgtcgccggtcgtatgcag
gagctctgcggcatcaagggcgcggcgattattgacgacacatacaacgccaaccccggc
tcggtggctgcagcgattgagttgttggcacagcgccgcggcaagcgcgttctagtgctc
ggcgacatggccgaactgggagcggatgcagaggaaatgcaccgtcaaatgggcgagctg
gcgcgggaacgcggcctggatgccctgtttacccttgggccgctgggtgccgccgccagt
gttgccttcagtgccgggcgtcacttgcccctgcacagttatagggacaggcagccgctt
atcgcggcgttgacccatgaattgaataaaaacaccacagtgctggtgaaaggttcccgc
agtgcccgtatggaactggtggtgcaggcactctgtgggaacgccaaagaggataaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (46)   

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