KEGG   Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_3122
Entry
ERDMAN_3122       CDS       T02526                                 
Symbol
cysG
Name
(GenBank) multifunctional uroporphyrinogen IIImethylase/precorrin-2 oxidase/ferrochelatase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
mtn  Mycobacterium tuberculosis Erdman = ATCC 35801
Pathway
mtn00860  Porphyrin metabolism
mtn01100  Metabolic pathways
mtn01110  Biosynthesis of secondary metabolites
mtn01120  Microbial metabolism in diverse environments
mtn01240  Biosynthesis of cofactors
Module
mtn_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:mtn00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    ERDMAN_3122 (cysG)
Enzymes [BR:mtn01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     ERDMAN_3122 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     ERDMAN_3122 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     ERDMAN_3122 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 2-Hacid_dh_C Asparaginase_C
Other DBs
NCBI-ProteinID: BAL66901
UniProt: A0A0H3LH47
Position
complement(3143063..3144280)
AA seq 405 aa
MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS
VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG
LSVGVLAGGEHRRSAAIRSAIREALQQGVITAQSSDVLSGGVALVGGGPGDPELITVRGR
RLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSGNFV
VRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEFVVV
SGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQHGTT
AAQQTLRATLADTPEKVRAAGIRPPAIIVIGAVVGLSGVRGLNNS
NT seq 1218 nt   +upstreamnt  +downstreamnt
gtgaccgagaacccctatctggtcgggttacggctggctggcaagaaggtcgtcgtggtt
ggcgggggcacggtcgcccagcgccggttacccctgctgatcgccagtggcgcggacgtg
cacgtgatcgcccccagcgtcacccccgccgtcgaggcgatggaccagatcaccttgtcg
gtgcgtgactaccgcgacggcgaccttgacggcgcctggtatgcgatcgcggccaccgat
gacgcgcgggtgaacgtggctgtcgtcgccgaggcggagcgccgacggatcttttgcgtc
cgggccgatatcgcggtggaggggacggcggtgaccccggcgtcattcagctatgcgggc
ctgtcggtgggggtgctcgccggtggtgagcaccgccgttcggcggcgatccgctcggca
atccgggaggcgttgcagcagggcgtcatcactgcgcagagttccgacgtcctcagcggc
ggagtggcgttggtcggcggcggtcccggcgatcccgaactgatcacggttcgcggtcgc
cggctgcttgcccaggccgatgtcgtggtcgccgaccggctcgccccgcccgaactgctg
gccgagctgccgccgcacgtagaagtcatcgacgcggccaagatcccttacggccgggcc
atggcccaggacgcgatcaacgctgtcctgatcgaacgggccagatccggcaactttgtg
gtccgtctcaaagggggcgaccccttcgtgttcgcccggggctatgaagaagtgctggca
tgtgcccacgccggaatcccggtcaccgtggtgccaggtgtgacgagtgccatagccgtg
cccgctatggcgggcgttccagtcactcaccgggccatgacccacgaattcgtggtggtc
agtggccatcttgcgcccggtcatcccgaatcgttagtgaattgggatgcattggctgca
ttgacgggcaccatcgttttgctgatggcggtcgaacgcatcgagcttttcgttgacgtt
ctgctaaagggtggccgaactgcggatacgccggtactggtggttcaacacggaacgacc
gccgctcaacagacgttgcgggccacccttgccgacacgccggagaaggtccgcgcggcg
gggatccgacctcccgcgatcatcgtgatcggggctgtagtcggcctgagcggcgttcgg
ggtttaaacaattcttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (34)   

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