KEGG   Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_3992
Entry
ERDMAN_3992       CDS       T02526                                 
Symbol
topA
Name
(GenBank) DNA topoisomerase I
  KO
K03168  DNA topoisomerase I [EC:5.6.2.1]
Organism
mtn  Mycobacterium tuberculosis Erdman = ATCC 35801
Brite
KEGG Orthology (KO) [BR:mtn00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mtn03032]
    ERDMAN_3992 (topA)
   03400 DNA repair and recombination proteins [BR:mtn03400]
    ERDMAN_3992 (topA)
Enzymes [BR:mtn01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     ERDMAN_3992 (topA)
DNA replication proteins [BR:mtn03032]
 Prokaryotic type
  DNA Topoisomerases
   ERDMAN_3992 (topA)
DNA repair and recombination proteins [BR:mtn03400]
 Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      ERDMAN_3992 (topA)
SSDB
Motif
Pfam: Topoisom_bac Toprim_C_rpt Toprim Toprim_4 DUF2092
Other DBs
NCBI-ProteinID: BAL67763
UniProt: A0A0H3LJY0
Position
complement(4065164..4067968)
AA seq 934 aa
MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVP
AKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIA
WHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSP
VLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFS
ARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYA
RRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAART
QARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLY
ELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVG
GEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSI
IKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERR
TNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVG
KNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHE
IVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDA
LRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAE
PKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDER
AAELLADRRARGPAKRPARKAARKVPAKKAAKRD
NT seq 2805 nt   +upstreamnt  +downstreamnt
ttggctgacccgaaaacgaagggccgtggcagcggcggcaatggcagcggccggcgactg
gtcatcgtcgagtcgcccaccaaggcgcgcaagctggcctcctacctgggctctggctac
atcgtcgagtcctcccgggggcacatccgtgacttgccgcgggccgcgtcggatgtaccc
gcaaagtacaagtcgcagccgtgggcgcggctcggggtcaacgtcgacgccgacttcgaa
ccgctctacatcatcagcccggagaaacggagcaccgtcagcgagctcaggggcctgctc
aaagacgtggacgagctgtatctggccacggatggggaccgtgagggcgaagctattgcc
tggcatctgctggaaaccctcaaaccgcgcataccggtaaagcggatggtcttccacgag
atcaccgaaccggcgatccgcgccgccgccgagcatccccgcgacctagacatcgacctg
gtcgacgcgcaggagacccggcgcatcctggaccggctgtacggctacgaagtcagccca
gtgctgtggaagaaggtcgcccccaagttgtcggcgggccgggtgcagtcggtggccacc
cgcatcatcgtggcgcgcgaacgcgaccgcatggcgttccgcagcgcggcctactgggac
atccttgccaagctggatgccagcgtgtccgacccggacgccgcgccgcccaccttcagc
gcccggctgacggccgtggctggccggcgggtggccactggccgcgatttcgactcgctg
ggcacgctgcgcaaaggcgacgaagtcattgtgctcgacgaggggagcgcgaccgcgttg
gccgcgggcctggatggcacgcagctgaccgtggcctcggccgaggagaagccctacgcc
cggcgcccgtacccgccgttcatgacctccacgctgcagcaagaggccagccgcaagctg
cggttctccgccgagcggacgatgagcatcgcccagcggctgtacgaaaacggctacatc
acctatatgcgtaccgactccaccacgctgtcggagtcggcgatcaacgccgcacgtacc
caggcgcgccagctctacggcgacgagtacgtcgcgccggcgccgcgccaatacacccgc
aaggtgaagaacgcccaggaagcgcacgaggctatccggcccgccggtgaaacgtttgcc
accccggacgcggtgcgtcgcgaactcgacggtcccaacattgatgatttccggctctat
gagctgatttggcaacgcaccgtagcctcgcagatggccgatgcgcggggcatgacgctg
agcctgcggatcactggcatgtcggggcaccaggaggtggtgttctccgcgaccggacgc
accttgacgttcccgggcttcctcaaggcctacgtggagaccgtggacgagctggtcggc
ggcgaggctgacgatgccgagcggcgactgccccatctgaccccgggtcaacggttggac
atcgtcgagttgaccccagacggccatgccaccaacccgccggcccgctacaccgaggcg
tcgctggtcaaagcgctcgaggagctgggcatcggccgcccgtcgacctactcgtcgatc
atcaagaccatccaggatcgcggctacgtgcacaagaagggcagtgcactggtgccgtca
tgggtggcgttcgcggtaaccggtctgctcgagcagcatttcggtcggctcgtcgactac
gacttcaccgcggcgatggaagacgagctcgacgagatcgccgccggcaacgagcgccgc
accaactggctcaacaacttctactttggtggcgatcacggtgtgcccgattcggtagcc
cgatcgggtggcctcaagaagcttgtcgggatcaatctcgagggcatcgacgcacgagaa
gtaaactctatcaagctttttgacgacacccacggacgccccatatatgttcgggtgggc
aagaacggtccctacctggaacgtttggtggccggcgacaccggtgagcccacgccgcag
cgggccaacctcagcgactcgattaccccggacgagctgactctacaggtggccgaagag
ctctttgccacaccgcaacagggacggactttgggcttggacccagaaaccggccacgag
atcgtggccagggaaggccggtttgggccgtatgtgaccgagatcctgccggagcctgcg
gctgatgcggccgcggccgctcagggagtcaagaaacgccagaaggccgccgggcccaaa
ccgcgcaccggttcgttgctgcggagcatggacctacagacggtcaccctcgaagacgcg
ctgaggctgctgtcactgccgcgcgtggtcggagtggaccccgcctcgggtgaggagatc
accgcgcagaacgggcgctacggaccgtatctaaagcgcggcaacgattctcgatcactg
gtcaccgaagaccagatattcaccatcacgctcgacgaagccctgaagatctacgcagag
ccgaaacgtcgtggccggcaaagcgcttcggctccgccgctgcgcgagctgggaacagat
ccggcgtcgggcaagccaatggtcatcaaggacggccgattcgggccgtacgtcaccgac
ggtgagaccaatgccagcctgcgtaagggcgacgacgtggcttccataaccgacgagcgc
gccgccgagctgttggccgatcgccgagcccggggtccggcaaaacggccagccaggaaa
gctgcccggaaggtgccggcgaagaaggcagccaagcgcgactag

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Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (15)   

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