KEGG   Mycobacterium tuberculosis H37Rv: Rv0753c
Entry
Rv0753c           CDS       T00015                                 
Symbol
mmsA
Name
(RefSeq) methylmalonate-semialdehyde dehydrogenase
  KO
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00280  Valine, leucine and isoleucine degradation
mtu00410  beta-Alanine metabolism
mtu00562  Inositol phosphate metabolism
mtu00640  Propanoate metabolism
mtu01100  Metabolic pathways
mtu01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    Rv0753c (mmsA)
   00562 Inositol phosphate metabolism
    Rv0753c (mmsA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    Rv0753c (mmsA)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    Rv0753c (mmsA)
Enzymes [BR:mtu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18  malonate-semialdehyde dehydrogenase (acetylating)
     Rv0753c (mmsA)
    1.2.1.27  methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
     Rv0753c (mmsA)
SSDB
Motif
Pfam: Aldedh LuxC
Other DBs
NCBI-GeneID: 888707
NCBI-ProteinID: NP_215267
TubercuList: Rv0753c
UniProt: O53816
Position
complement(844421..845953)
AA seq 510 aa
MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA
WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL
KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP
SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA
TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR
ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL
TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE
YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA
IQFYTKVKTVTSRWPSGIKDGAEFVIPTMS
NT seq 1533 nt   +upstreamnt  +downstreamnt
atgaccacacagatttcacatttcatcgacggacaacgcaccgccggccagtccacgcgc
tcggccgacgtcttcgaccccaacaccggccagatccaggcgaaggtaccgatggccggc
aagtcagacatcgacgcggccgtggcctccgcggtcgaggcccaaaagggctgggccgca
tggaatccccagcgccgtgcccgggtgttgatgcggtttatcgaactggtcaacgacacc
atcgacgagttggccgagctgttgtcgcgtgagcacggcaaaacgctggccgacgcccgc
ggcgacgtccagcgcggcatcgaggtaatcgagttctgcctgggcattccccacctgctc
aagggcgagtacaccgagggtgccggccccggcatcgacgtctattcgctgcggcagccc
ctgggtgtggtcgcggggatcaccccgttcaacttcccggcgatgattccgctgtggaag
gccggcccggccctagcgtgcggcaacgccttcgtgctcaagccaagtgagcgcgacccg
tcggttccggtgaggctggccgagctgttcatcgaggcgggcctgccggcgggcgtgttc
caggtggtgcacggcgacaaggaggccgtcgacgccatcctgcaccaccccgacatcaag
gccgtcggcttcgtcggcagctcggatatcgctcagtacatctacgctggtgccgccgcc
accggcaagcgggcgcagtgtttcggcggtgccaagaaccacatgatcgtgatgcccgac
gcggacctggatcaggccgtggacgcactgatcggcgccggatacggcagcgccggcgaa
cgctgcatggcgatcagcgtcgccgtgccggtgggcgatcagaccgcggagcggttgcgc
gccaggctgatcgagcggatcaataacttgcgggtgggacacagcctggaccccaaggcg
gactacggcccgctggtcaccggggcggcgctggcgcgggtgcgcgactacatcggccag
ggtgtggccgccggtgccgagctggtcgttgacggccgcgaccgcgccagcgacgacctg
acctttgggctgcctgaaggcgatgcgaacctggagggcggcttcttcatcgggccgacc
ctgttcgaccatgtcgctgcccacatgtcgatctacaccgacgaaatcttcgggccggtg
ttgtgcatggttcgcgcccgcgactacgaagaggcgttgcggctgccgtcggagcacgaa
tacggcaacggggtggcgatcttcacccgcgacggcgacgcggcccgcgacttcgtctcc
cgggtgcaggtgggcatggtcggcgtcaacgtgccgatcccggtgccggtggcctaccac
actttcggcggctggaagcgctccggcttcggcgacctcaaccagcacggcccggcggca
atccagttctacaccaaggtcaagaccgtcacgtcgcgatggccgtcaggcatcaaggac
ggtgccgaattcgtcatccccacaatgagttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (47)   

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