KEGG   Mycobacterium tuberculosis EAI5/NITR206: J114_11380
Entry
J114_11380        CDS       T02653                                 
Name
(GenBank) 5-methyltetrahydrofolate-homocysteinmethyltransferase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mtue  Mycobacterium tuberculosis EAI5/NITR206
Pathway
mtue00270  Cysteine and methionine metabolism
mtue00450  Selenocompound metabolism
mtue00670  One carbon pool by folate
mtue01100  Metabolic pathways
mtue01110  Biosynthesis of secondary metabolites
mtue01230  Biosynthesis of amino acids
mtue04980  Cobalamin transport and metabolism
Module
mtue_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mtue00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    J114_11380
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    J114_11380
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    J114_11380
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    J114_11380
Enzymes [BR:mtue01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     J114_11380
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding HTH_39 Na_Ca_ex_C
Other DBs
NCBI-ProteinID: AGL31611
Position
complement(2375290..2378868)
AA seq 1192 aa
MTAADKHLYDTDLLDVLSQRVMVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVL
ETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSQKGTAIARRVADELGSPDRK
RYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLG
SRRAMTRAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HLRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVGGCCGT
TPAHIREVAGAGANIKRPERQVSYEPSVSSLYTAIPFAQDASVLVIGERTNANGSKGFRE
AMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDST
ETAVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQART
AQKKVEIAERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELKKRH
PDVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRNV
ALDLVYDRRREDYDPLQELMRLFEGVSAASSKEDRLAELAGLPLFERLAQRIVDGERNGL
DADLDEAMTQKPPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHM
ERSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKS
ADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYQGEVH
YARDAFEGLKLMDTIMSAKRGEAPDENSPEAIKAREKEAERKARHQRSKRIAAQRKAAEE
PVEVPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGP
SYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGNDIVVLTEPKPDAPVRY
RFHFPRQQRGRFLCIADLIRSRELAAERGEVDVLPFQLVTMGQPIADFANELFASNAYRD
YLEVHGIGVQLTEALAEYWHRRIREELKFSGDRAMAAEDPEAKEDYFKLGYRGARFAFGY
GACPDLEDRAKMMALLEPERIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
NT seq 3579 nt   +upstreamnt  +downstreamnt
gtgactgcggccgacaagcacctctacgacaccgatctgctcgacgtcttgtcgcagcga
gtgatggtcggcgacggtgcaatgggaacccaactacaggccgcggacctcacgctcgac
gacttccgcggcctggagggctgcaacgagatcctcaacgaaacccgccctgacgtgctg
gaaaccattcaccgcaactatttcgaagcgggcgccgacgccgtcgagacgaacacgttt
ggctgcaacctgtccaacctcggcgactacgacatcgccgacaggatccgcgatctatca
cagaagggcaccgcgatcgcacgccgggtggccgacgagctgggcagtcccgaccgcaag
cgctacgtgctggggtcgatggggccgggcaccaagctgccgactctgggccacaccgaa
tacgcggtgatccgcgacgcctacaccgaggccgcgctgggcatgctggacggcggagcc
gacgccatcctggtggaaacctgccaggacctactgcagctgaaggcggcggtgttgggg
tcgcggcgggcgatgacgcgggccgggcggcacattccggtgtttgcccacgtcaccgtc
gagaccaccggcaccatgctgctgggcagcgagatcggggcggcgttgaccgctgtcgag
ccgctcggtgtggacatgatcggcttgaactgcgcgacgggtccggccgagatgagcgag
cacctgcgccacctgtcccggcacgcccgcatcccggtgtcggtgatgcccaacgccggg
ttgccggtgctgggcgccaagggcgccgaatatccgttgctgcccgacgaattggccgag
gcgctggccggcttcatcgccgagttcgggctctcgctggtcggtggctgctgcggcacc
accccggcccatatccgcgaagtggctggcgcgggtgcgaacatcaagcgtcccgagcga
caggtcagctacgagccgtcggtgtcgtcgctgtacaccgcaatcccgttcgcccaggac
gcctcggttctggtgatcggggagcgaacgaacgccaacggctccaagggttttcgtgag
gcgatgatcgccgaggactaccagaagtgcctggacatcgccaaggaccagacccgcgac
ggcgcccacctgctggacctgtgtgtggactacgtgggccgcgacggtgtggccgacatg
aaggcgctggccagccggctggccacgtcctcgacgctgccgatcatgctggactccacc
gaaaccgcggtgctgcaggcgggtttggagcatctgggtggccgttgcgcgatcaactcg
gtgaactacgaggacggcgacggcccggaatcgcgctttgccaagaccatggcgctggtc
gccgagcacggcgcggcggtggtcgcgctgaccatcgacgaagagggccaggcccgcacc
gcgcagaagaaggtcgagatcgccgagcggctgatcaacgacatcaccggcaactggggc
gtcgacgaatcatccatcctcatcgacaccttgacgttcaccatcgccaccggtcaggag
gagtcccgccgcgacggcatcgagaccatcgaggcgatccgcgaactgaaaaagcgccac
ccggatgtgcagaccacacttggtctgtccaacatctcgtttggtctcaatcccgcagcg
cgccaggtgctcaactcggtgttcctgcacgaatgccaagaagcggggctggattcggcg
atcgtgcacgcgtcgaagatcctgccgatgaaccggattcccgaggagcaacgcaacgtc
gccctggatctggtctacgaccgccgccgcgaggactacgatccgctgcaggagctgatg
cggctgttcgaaggcgtgtcggcggcctcctcgaaagaggaccgactggctgaactagct
gggctgccgctgttcgaacggctggcccaacgcatcgtcgacggcgagcgcaacggcctg
gacgccgatctcgacgaggcgatgacgcaaaagccgccgcttcagatcatcaacgaacat
ctgctggccggcatgaagacggtcggcgagctcttcggctccggccagatgcagctgccg
ttcgtgctgcagtcggcggaggtaatgaaagccgccgtcgcgtatctggaaccgcacatg
gagcgctcggacgacgattcgggcaagggacgcatcgtgctggccaccgtcaagggcgac
gtgcacgacatcggcaagaacctggtcgacatcatcttgagcaacaacggctacgaagtg
gtcaacatcggcatcaagcagccaatcgccaccatcctcgaagtcgccgaggacaagagc
gccgacgtggtcggcatgtcgggcctgctggtgaagtcgaccgtggtgatgaaggaaaac
ctcgaggagatgaacacccggggagtcgccgaaaagttcccggtgctgctcggcggcgcg
gcgttgacgcgcagctatgtcgaaaacgacctggccgagatctaccagggcgaagtgcat
tacgcgcgagacgctttcgagggcctgaagttgatggacaccatcatgagcgccaagcgc
ggcgaggcgcccgacgaaaacagcccggaagccattaaggcgcgtgagaaagaagccgaa
cgtaaggcccgccaccagcgatccaaacgcattgccgcacagcgcaaagccgccgaagaa
ccagtcgaggtgcccgaacgctccgatgtcgcggccgacatcgaggtcccggcgccgccg
ttctggggttcgcggatcgtcaagggcctggcggtggccgactacaccggtctgctcgat
gagcgcgcattgtttttgggccagtggggtttacgcggccagcgcggcggtgagggtccg
tcctacgaagatctcgtcgagaccgagggccggccgcggctgcggtactggttggaccgg
ctgtccaccgacggcatcttggcgcacgccgccgtggtgtacggctatttcccggcggtg
tccgagggcaacgacatcgtggtgctcaccgagcccaagcccgacgccccggtgcgctac
cggtttcacttcccgcgccagcagcgcggtcggtttttgtgcattgccgatttaatccgc
tcgcgggagctggccgccgagcgtggcgaggttgacgtgctgccgttccagctggtgacc
atgggtcagccgatcgcggatttcgccaacgagctgttcgcgtccaacgcctaccgcgac
tacctggaggtgcacggtatcggcgtgcagctcaccgaggcgctggccgagtactggcac
cggcggatccgtgaggagctcaagttctccggggatcgggcgatggcggccgaggatccg
gaggcgaaagaagactatttcaagctcggctaccgcggtgctcgctttgccttcggctac
ggcgcatgcccggatctggaggaccgcgccaagatgatggcgctgctggagcccgaacgc
atcggtgtgacgttatccgaggaattacagctgcatcccgaacagtcgaccgacgcgttc
gtcctgcaccatccggaagccaagtacttcaacgtttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (7)   
   Pfam (7)   
All databases (32)   

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