KEGG   Myotis davidii (David's myotis): 102770795
Entry
102770795         CDS       T02992                                 
Symbol
IGF1R
Name
(RefSeq) insulin like growth factor 1 receptor
  KO
K05087  insulin-like growth factor 1 receptor [EC:2.7.10.1]
Organism
myd  Myotis davidii (David's myotis)
Pathway
myd01521  EGFR tyrosine kinase inhibitor resistance
myd01522  Endocrine resistance
myd04010  MAPK signaling pathway
myd04014  Ras signaling pathway
myd04015  Rap1 signaling pathway
myd04066  HIF-1 signaling pathway
myd04068  FoxO signaling pathway
myd04114  Oocyte meiosis
myd04140  Autophagy - animal
myd04144  Endocytosis
myd04150  mTOR signaling pathway
myd04151  PI3K-Akt signaling pathway
myd04152  AMPK signaling pathway
myd04211  Longevity regulating pathway
myd04213  Longevity regulating pathway - multiple species
myd04510  Focal adhesion
myd04520  Adherens junction
myd04550  Signaling pathways regulating pluripotency of stem cells
myd04730  Long-term depression
myd04913  Ovarian steroidogenesis
myd04914  Progesterone-mediated oocyte maturation
myd05200  Pathways in cancer
myd05202  Transcriptional misregulation in cancer
myd05205  Proteoglycans in cancer
myd05214  Glioma
myd05215  Prostate cancer
myd05218  Melanoma
myd05224  Breast cancer
myd05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:myd00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102770795 (IGF1R)
   04014 Ras signaling pathway
    102770795 (IGF1R)
   04015 Rap1 signaling pathway
    102770795 (IGF1R)
   04066 HIF-1 signaling pathway
    102770795 (IGF1R)
   04068 FoxO signaling pathway
    102770795 (IGF1R)
   04151 PI3K-Akt signaling pathway
    102770795 (IGF1R)
   04152 AMPK signaling pathway
    102770795 (IGF1R)
   04150 mTOR signaling pathway
    102770795 (IGF1R)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102770795 (IGF1R)
   04140 Autophagy - animal
    102770795 (IGF1R)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102770795 (IGF1R)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102770795 (IGF1R)
   04520 Adherens junction
    102770795 (IGF1R)
   04550 Signaling pathways regulating pluripotency of stem cells
    102770795 (IGF1R)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    102770795 (IGF1R)
   04914 Progesterone-mediated oocyte maturation
    102770795 (IGF1R)
  09156 Nervous system
   04730 Long-term depression
    102770795 (IGF1R)
  09149 Aging
   04211 Longevity regulating pathway
    102770795 (IGF1R)
   04213 Longevity regulating pathway - multiple species
    102770795 (IGF1R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102770795 (IGF1R)
   05202 Transcriptional misregulation in cancer
    102770795 (IGF1R)
   05205 Proteoglycans in cancer
    102770795 (IGF1R)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    102770795 (IGF1R)
   05214 Glioma
    102770795 (IGF1R)
   05218 Melanoma
    102770795 (IGF1R)
   05215 Prostate cancer
    102770795 (IGF1R)
   05224 Breast cancer
    102770795 (IGF1R)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102770795 (IGF1R)
   01522 Endocrine resistance
    102770795 (IGF1R)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:myd01001]
    102770795 (IGF1R)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:myd04090]
    102770795 (IGF1R)
Enzymes [BR:myd01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102770795 (IGF1R)
Protein kinases [BR:myd01001]
 Receptor tyrosine kinases (RTK)
  INSR family [OT]
   102770795 (IGF1R)
CD molecules [BR:myd04090]
 Proteins
  102770795 (IGF1R)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain Furin-like Pkinase fn3 Insulin_TMD Kinase-like
Other DBs
NCBI-GeneID: 102770795
NCBI-ProteinID: XP_015424597
Position
Un
AA seq 1192 aa
MKSPLGGGSLASLWALLLLAAALAFWPTSGEICGPGIDIRNDFQQLKRLENCTVIEGYLH
ILLISKGDDYRSYRFPKLTVITEYLLLFRVAGLESIGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLRNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYVVGNKSPKECGD
VCPGALEGKSTCDRTTINNEYNYRCWTQDHCQKTCPSACGKRACTENNECCHPECLGGCT
APDDEAACVACKHYYHEGVCVTDCPPNTYRFEGWRCVDRDFCATIPNADSFELEGFVIHD
GECMQECPSGFIRNDSLSMYCIPCEGPCPKICEEDKGTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYIKIRHSHALVSLSFFKSLRQILGEDQLEGPYKN
VTEYDGQDACGSNSWNMVDVDLPANKDMEPGILLHGLKPWTQYAIYVKAVTLTMVDNDHI
RGAKSDILYLRTNASVPSIPLDVISASNSSSQLIVKWNPPSLPNGNLSYYIVRWQQQPQD
AYLYQHNYCSKDKLPVRKYTEGVFDIEEVTENPKTESCNTPKGPCCACPKTEAEKQAEKE
EAEYRKVFENFLHNSIFVPRPDRKRRDVGQISNTTLSGRSRNSTVTDPFNSTDSDDRETD
YPFFESRVDKKERTVISNLKPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPADGADDI
PGPITWEVKPDNTIFLKWPEPENPNGLILTYEIKYGSQVEDQRECVSRQDYRKHGGAKLQ
KLTPGNYTARIQATSLSGNGSWTEPVFFYVQDKAAYDSHAHLVIALPIAIVLTVLGLALT
LYIIHRKRNRMGNGVLYASVNPEYFSAADGKLSSLRGGAGPAAFGRVAHLGEEEVCMTWR
YSVFGNTSLHKKNQRWIFDLQRVSSPPLCLPPSLPPSQVRLLGVVSQGQPTLVIMELMPR
GDLKSYLRSLRPEIENHPVLSPPTLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA
EDLTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWE
IATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMQVCWHFNPKMRPSFLDIIG
SIKDELEPGFIEVSFYYSDENKPPDTEELDLDPDQLECVPLDXSASCSYRGI
NT seq 3579 nt   +upstreamnt  +downstreamnt
atgaagtcgcccctcggaggagggtccctggcctcgctgtgggcgctcctgcttctggcc
gccgcgctcgccttctggccgacgagcggagaaatctgcggccccggcatcgacatccgc
aacgacttccagcagctgaagcgcctggagaactgcacggtgatcgagggctacctgcac
atcctgctcatctccaagggcgacgactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctcctgttccgcgtggccggcctggagagcatcggcgacctgttc
cccaacctcacggtcatccgcggctggaagctcttctacaactacgcgctggtcatcttc
gagatgaccaacctcaaggacatcggcctgcgcaacctgcgtaacatcacccgcggcgcc
atccgcatcgagaagaacgccgacctctgctacctgtccaccgtggactggtccctcatc
ctcgacgccgtgtccaacaactacgtggtggggaacaagtcccccaaggagtgcggcgac
gtgtgcccgggggccctggaggggaagtccacctgcgaccggaccaccatcaacaacgag
tacaactaccgctgctggacccaggaccactgccagaaaacctgcccgagcgcgtgcggg
aagcgggcgtgcacggagaacaacgagtgctgccaccccgagtgcctgggcggctgcacg
gcccccgacgacgaggcggcctgcgtggcctgcaagcactactaccacgagggcgtctgc
gtgaccgactgtccccccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaccatccccaacgccgacagcttcgagctggagggcttcgtcatccacgac
ggcgagtgcatgcaggagtgcccctccggcttcatccgcaacgacagcctgagcatgtac
tgcatcccctgcgaaggaccgtgccccaaaatctgtgaggaagacaaggggacaaagacc
atcgactcggtgacctcggctcagatgctccagggctgcaccatcttcaagggcaacctg
ctcattaacatccgcaggggcaataacatcgcctcggaactggagaacttcatggggctc
atcgaggtggtcacgggctacatcaagatccgccactcccatgcgctggtctccctgtcc
ttcttcaagagcctccgccagatcctcggcgaggaccagctggaggggccctacaagaac
gtcaccgagtacgacggccaggacgcctgcggctccaacagctggaacatggtggacgtg
gacctgcccgccaacaaggacatggagcccggcatcctgctgcacggcctgaagccctgg
acgcagtacgccatctacgtgaaggccgtgacgctgaccatggtggacaacgaccacatc
cgcggggccaagagcgacatcctctacctccgcaccaacgcctcagtgccttccatcccc
ctggatgtcatctcggcctccaactcgtcctcccagctgatcgtcaagtggaacccgccc
tccctgcccaacggcaacctgagctactacatcgtgcgctggcagcagcagccgcaggac
gcctacctgtaccagcacaactactgctccaaagacaagctccccgtccgcaagtacaca
gagggcgtcttcgacatcgaggaggtgacggagaaccccaagaccgagtcgtgcaacacc
cccaaggggccctgctgcgcgtgtcccaaaaccgaggccgagaagcaggcggagaaggag
gaggccgagtaccgcaaagtctttgagaacttcctgcacaactccatcttcgtgcccagg
cccgacaggaaacgcagggacgtgggccagatctccaacaccaccctctccggccggagc
aggaacagcacggtgacggaccccttcaacagcacggactcggacgacagggagacggac
taccctttcttcgagagcagggtggacaagaaggagaggaccgtcatctccaacctgaag
cccttcaccctctaccgcatcgacatccacagctgcaaccacgaggccgagaagctgggc
tgcagcgcctccaacttcgtctttgcgagaaccatgcctgcagacggagcggatgacatt
cccgggccgataacctgggaggtgaagcctgacaacaccatcttcttaaagtggccggaa
ccggagaatcccaacggtctgattctcacgtatgagataaaatacgggtcgcaggtcgag
gaccagcgggagtgcgtgtcgcggcaggactaccggaagcacggaggggccaagctgcag
aagctcaccccggggaactacacggcccgcatccaggccacctctctgtcggggaacggg
tcctggacagagcccgtgttcttctacgtccaggacaaagcagcgtatgacagtcacgcc
cacctggtcatcgcgctgcccatcgccatcgtgctgaccgtcctggggctggccctcacg
ctgtacatcatccacaggaagcgtaatcggatggggaacggagtgctgtacgcgtctgtg
aaccccgagtatttcagcgcggccgacggtaagctcagctccctgcgtgggggcgccggt
ccggccgctttcgggagggtggctcacctcggggaggaagaggtctgcatgacttggagg
tactctgtcttcggtaacacttctttacataaaaaaaaccaaaggtggatcttcgactta
cagcgtgtctccagtcctcctctctgtctccctccctccctccctccctcccaggtgcgt
ttgctgggagtggtgtcccagggccagccaaccctggtcatcatggagctcatgccccgc
ggagacctcaagagttacctcaggtctctgagaccggaaatcgagaaccaccccgtcctc
tcgccgccgaccctcagcaagatgatccagatggcaggggagattgcggatggcatggcg
tacctcaacgccaacaagttcgtccacagggacctggctgcccggaactgcatggtggct
gaggatttgaccgtcaagatcggagacttcggcatgactcgcgacatctacgagaccgac
tattaccggaagggcgggaaggggctgctgcctgtgcgctggatgtcccccgagtccctc
aaggacggcgtgttcaccacccactctgatgtctggtccttcggcgtcgtgctctgggag
atcgccacgctggccgagcagccctaccagggcctgtccaacgagcaggttctgcgcttc
gtcatggagggcggccttctggacaagcccgacaactgccctgacatgctgttcgagctc
atgcaggtgtgctggcacttcaaccccaagatgcggccttcgttcctggacatcatcggc
agcatcaaggacgagctggagcccggcttcatcgaggtgtccttctactacagcgacgag
aacaagccgcccgacaccgaggagctggacctggaccccgaccaactggagtgcgtgccc
ctggaccnctcggcctcctgctcctatagggggatctag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (29)   
   KEGG PATHWAY (29)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (48)   

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